Postdoctoral fellowship in experimental biomedical research at the Department of Integrative Medical Biology

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Description of the position:
A Postdoctoral fellowship is now available at the laboratory of experimental ophthalmology research at the Department of Integrative Medical Biology, Umeå University.

We are looking for an enterprising postdoc, with great bench-experience from experimental biomedical research, to perform studies on the pathophysiology of different conditions affecting epithelium and connective tissues, with emphasis on the cornea of the eye. Our research team focuses on mechanistic aspects of wound healing in epithelium and connective tissue, and of collagen scar formation, more particularly the role of the collagen producing cells (the keratocytes). We aim at unravelling intra- and intercellular signalling pathways that may be targets for future drugs interfering with corneal wound healing and scar forming processes. The role of classical neuronal signal substances, such as substance P and acetylcholine, produced locally by non-neuronal cells, is a major focus of the project, as is the functional role of fibroblasts of different phenotypes in processes such as fibrosis, apoptosis, angiogenesis, and excessive collagen production.

The role of the new postdoc in the project would be to lead the experimental corneal research studies under the supervision of the PI/professor and a lab manager, as well as to support junior staff in adjoining projects (preferably studies on similar tissues within the musculoskeletal system). The fellowship will include a lot of challenging bench-work, but also require independent work on project design and advanced data analysis. The research is performed in collaboration with clinical researchers at the Dept. of Clinical Science, Ophthalmology, at the University Hospital of Umeå, as well as with researchers at the Shandong Eye Institute, Quingdao, China, and the University of British Columbia, Vancouver, Canada. The national Swedish Research Council (VR) and several private research foundations support the research.

Qualifications:
To receive the fellowship the applicant must have a doctoral degree (PhD), not more than three years old, and possess knowledge in molecular biology/biomedicine and bioengineering. Ample experience of molecular/biochemical laboratory techniques, in particular qPCR, Western blot, and EIA/ELISA, is required as well as experience from work on human primary cell cultures, primarily from connective tissue. Experience from work on animal models and/or flow cytometry (FACS) is considered as a strength, as is experience from work on connective tissues, and on fibrogenic as well as stem cells. It is presupposed that the candidate masters scientific English and have good general communication skills in English (written and verbal). The applicant must be able to work both independently and as part of a team. The candidate’s collaborative skills and suitability for the project are especially considered in the assessment of the candidate's qualifications.

Application for the position should include:

  1. A short cover letter (not more than 1 page) to include a brief summary of your research experience and interests, and a short statement telling why you are interested in this fellowship.
  2. Curriculum Vitae including: copies of appropriate certificates, list of scientific publications, list of technical expertise, education, and names and contact information for at least two reference persons.

For questions: Contact Ludvig Backman, E-mail: ludvig.backman@umu.se.

The fellowship is for two years. Starting date 1st of December 2017 or according to agreement.

We kindly decline offers of recruitment and advertising help.            

Other information:
Union information is available from SACO +46 (0)90-786 53 65, SEKO civil +46 (0)90-786 52 96 and ST +46 (0)90-786 54 31.

Applications that are submitted electronically should be in Word or PDF format

Your complete application, marked with reference number FS 2.1.6-1509-17, should be sent to medel@diarie.umu.se (state the reference number as subject) to arrive October 27th, 2017 at the latest.

We look forward to receiving your application!


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