Research projects

Head of research

Title

Date sorteringsordning

Thelander, Lars

Regulation of deoxyribonucleotide synthesis during DNA replication and repair in eukaryotes

02/26/2007

Publications

Author

Title

Year sorteringsordning

Fulltext

Domkin, Vladimir
Chabes, Andrei

Phosphines are ribonucleotide reductase reductants that act via C-terminal cysteines similar to thioredoxins and glutaredoxins
Scientific Reports, 4: 5539-

2014

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Björnberg, O
Vodnala, Munender
Domkin, Vladimir; et al.

Ribosylurea accumulates in yeast urc4 mutants
Nucleosides, Nucleotides & Nucleic Acids, 29(4-6): 433-437

2010

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Popović-Bijelić, Ana
Voevodskaya, Nina
Domkin, Vladimir; et al.

Metal binding and activity of ribonucleotide reductase protein R2 mutants: conditions for formation of the mixed manganese-iron cofactor
Biochemistry, 48(27): 6532-6539

2009

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Håkansson, Pelle
Dahl, Lina
Chilkova, Olga; et al.

The Schizosaccharomyces pombe replication inhibitor Spd1 regulates ribonucleotide reductase activity and dNTPs by binding to the large Cdc22 subunit.
Journal of Biological Chemistry, 281(3): 1778-1783

2006

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Voevodskaya, N
Narvaez, A-J
Domkin, Vladimir; et al.

Chlamydial ribonucleotide reductase: tyrosyl radical function in catalysis replaced by the FeIII-FeIV cluster.
Proceedings of the National Academy of Sciences of the United States of America, 103(26): 9850-4

2006

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Chabes, Andrei
Georgieva, Bilyana
Domkin, Vladimir; et al.

Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase.
Cell, 112(3): 391-401

2003

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Domkin, Vladimir
Thelander, Lars
Chabes, Andrei

Yeast DNA damage-inducible Rnr3 has a very low catalytic activity strongly stimulated after the formation of a cross-talking Rnr1/Rnr3 complex.
Journal of Biological Chemistry, 277(21): 18574-8

2002

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Chabes, Andrei
Domkin, Vladimir
Larsson, Göran; et al.

Yeast ribonucleotide reductase has a heterodimeric iron-radical-containing subunit
Proceedings of the National Academy of Sciences of the United States of America, 97(6): 2474-2479

2000

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Zhao, X
Georgieva, B
Chabes, Andrei; et al.

Mutational and structural analyses of the ribonucleotide reductase inhibitor Sml1 define its Rnr1 interaction domain whose inactivation allows suppression of mec1 and rad53 lethality.
Mol Cell Biol, 20(23): 9076-83

2000

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