A translational research unit associated with the Oncology Clinic at the University Hospital of Northern Sweden. Both basic scientists and clinicians are working in close collaboration, thereby creating a translational and highly stimulating environment.
The Oncology Research Laboratory at Umeå University is a translational research unit associated with the Oncology Clinic at the University Hospital of Northern Sweden.
Both basic scientists and clinicians are working in close collaboration, thereby creating a translational and highly stimulating environment. The laboratory is focusing on both basic and applied aspects of tumor biology. It is a well-equipped state-of-the-art cell and molecular biology laboratory with access to the university's animal facility including modern small animal imaging equipment for MRI, PET/CT, luminescence, and ultrasound.
Researchers at the laboratory discovered and pioneered work on the human tumor suppressor LRIG1 [for review, see ref. 1] and also recently contributed to the demonstration of the potential of using thrombocytes for the analysis of nucleic acid tumor biomarkers [e.g., ref. 2]. Researchers at the laboratory are also studying the molecular epidemiology of human cancer and other diseases [Regionalt Cancercentrum Norr].
Lindquist D, Kvarnbrink S, Henriksson R, Hedman H. LRIG and cancer prognosis. Acta Oncol. 2014 Sep;53(9):1135-42. doi: 10.3109/0284186X.2014.953258. Epub 2014 Sep 2. Review.
Nilsson RJ, Balaj L, Hulleman E, van Rijn S, Pegtel DM, Walraven M, Widmark A, Gerritsen WR, Verheul HM, Vandertop WP, Noske DP, Skog J, Würdinger T. Blood platelets contain tumor-derived RNA biomarkers. Blood. 2011 Sep 29;118(13):3680-3. doi: 10.1182/blood-2011-03-344408. Epub 2011 Aug 10.