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Image: Mattias Pettersson

Ellen Bushell Lab

Research group The group studies parasite-host interactions that govern malaria infection and disease.

The Ellen Bushell Lab is interested in the role of malaria parasite exported proteins in host-parasite interactions.

The malaria parasite invades and grows within red blood cells, which is the cause of malaria disease. The disease progression for any one malaria infection is determined by the interaction between the parasite and its host. Exported parasite proteins are at the coalface of these interactions.

The overall goal with the research in our lab is to better understand the molecular mechanisms through which parasite exported proteins interacts with its host. We do so by primarily using the rodent malaria parasite Plasmodium berghei in vivo infection model.

We use high-throughput phenotyping methods that combine pooled transfections and barcode sequencing technology to phenotype pools of ~100 of gene knock-out mutants in parallel (Gomes & Bushell et al. 2015, Bushell, Gomes and Sanderson et al. 2018). 

Head of research

Ellen Bushell
Research fellow
E-mail
Email

Overview

Participating departments and units at Umeå University

Department of Molecular Biology

Research area

Infection biology
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Takahiro Ishizaki from Japan is postdoctoral fellow in the Ellen Bushell group at MIMS.

International Malaria Day – outstanding research is ongoing at Umeå University

Dr Ellen Bushell and Professor Oliver Billker are prominent malaria researchers with exciting goals in mind.

Four questions to researcher Ellen Bushell - new Swedish Young Academy member

Ellen tells us about how one becomes a member of the Swedish Young Academy and how she plans to use her time.

Latest update: 2023-06-21