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Staff photo Christopher Fowler

Christopher Fowler

N-Acylethanolamines (NAE) are a family of lipids found in the body. Our research concerns whether NAE turnover is dysfunctional in illness, and whether it can be targeted for drug development

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hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

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Affiliation

N-Acylethanolamines (NAE) are a family of lipids in the body that can act as a defense mechanism to combat inflammation and other pathological events. My research seeks answers to two main questions: 1) is the "NAE defense" system substandard in chronic inflammatory disease states such that it contributes to disease development, and 2) can the effects of NAE molecules be optimally enhanced by blocking multiple pathways for their degradation. We are also interested in how the signalling mediated by NAEs and related lipids is involved in cancer development. The overall goal of the research is to identify novel targets for drug development.

2019
Cancer Investigation, Vol. 37, (8) : 327-338
Alhouayek, Mireille; Boldrup, Linda; Fowler, Christopher J
2019
British Journal of Pharmacology, Vol. 176, (10) : 1470-1480
Alhouayek, Mireille; Rankin, Linda; Gouveia-Figueira, Sandra C.; et al.
2019
Scientific Reports, Nature Publishing Group 2019, Vol. 9
Alhouayek, Mireille; Sorti, René; Gilthorpe, Jonathan D.; et al.
2019
Journal of Medicinal Chemistry, American Chemical Society (ACS) 2019, Vol. 62, (7) : 3336-3353
Chen, Zhen; Mori, Wakana; Deng, Xiaoyun; et al.
2019
Journal of enzyme inhibition and medicinal chemistry (Print), Taylor & Francis 2019, Vol. 34, (1) : 562-576
Deplano, Alessandro; Cipriano, Mariateresa; Moraca, Federica; et al.
2019
Acta Dermato-Venereologica, Acta Dermato-Venereologica 2019, Vol. 99, (11) : 1051-1052
Gouveia-Figueira, Sandra C.; Danielsson, Karin; Fowler, Christopher J
2019
British Journal of Pain, Vol. 13, (4) : 214-225
Rankin, Linda; Fowler, Christopher John; Stålnacke, Britt-Marie; et al.
2019
Prostaglandins & other lipid mediators, Elsevier 2019, Vol. 142 : 59-67
Szeremeta, Janis; Karlsson, Jessica; Alhouayek, Mireille; et al.
2018
British Journal of Pharmacology, WILEY 2018, Vol. 175, (6) : 877-890
Alhouayek, Mireille; Gouveia-Figueira, Sandra; Hammarström, Marie-Louise; et al.
2018
Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (6) : 2278-2291
Cheng, Ran; Mori, Wakana; Ma, Longle; et al.
2018
Scandinavian Journal of Pain, Walter de Gruyter 2018, Vol. 18, (3) : 533-544
Rankin, Linda; Stålnacke, Britt-Marie; Fowler, Christopher J; et al.
2017
Chemical Senses, OXFORD UNIV PRESS 2017, Vol. 42, (2) : E28-E28
Claeson, Anna-Sara; Gouveia-Figueira, Sandra; Fowler, Christopher J.; et al.
2017
Prostaglandins, Leukotrienes and Essential Fatty Acids, Vol. 121 : 60-67
Claeson, Anna-Sara; Gouveia-Figueira, Sandra; Häggström, Jenny; et al.
2017
European Journal of Medicinal Chemistry, Elsevier 2017, Vol. 136 : 523-542
Deplano, Alessandro; Morgillo, Carmine Marco; Demurtas, Monica; et al.
2017
Pharmacology Research & Perspectives, JOHN WILEY & SONS LTD 2017, Vol. 5, (2)
Gabrielsson, Linda; Gouveia-Figueira, Sandra; Häggström, Jenny; et al.
2017
Prostaglandins, Leukotrienes and Essential Fatty Acids, Vol. 120 : 15-24
Gouveia-Figueira, Sandra; Goldin, Kristina; Hashemian, Sanaz A.; et al.
2017
Innate Immunity, Vol. 23, (8) : 687-696
Hashemian, Sanaz; Alhouayek, Mireille; Fowler, Christopher J.
2017
PLoS ONE, PUBLIC LIBRARY SCIENCE 2017, Vol. 12, (9)
Karlsson, Jessica; Gouveia-Figueira, Sandra; Alhouayek, Mireille; et al.
2017
Journal of enzyme inhibition and medicinal chemistry (Print), Vol. 32, (1) : 513-521
Sunduru, Naresh; Svensson, Mona; Cipriano, Mariateresa; et al.
2016
British Journal of Clinical Pharmacology, Vol. 82, (4) : 932-942
Gabrielsson, Linda; Mattsson, Sofia; Fowler, Christopher J.
2016
BMC Musculoskeletal Disorders, Vol. 17
Hellström, Fredrik; Gouveia-Figueira, Sandra; Nording, Malin L.; et al.
2015
European Neuropsychopharmacology, Vol. 25, (6) : 749-762
Fowler, Christopher J.
2015
Clinical Pharmacology and Therapeutics, Wiley-Blackwell 2015, Vol. 97, (6) : 587-596
Fowler, Christopher J
2015
Endocannabinoids, Springer International Publishing 2015 : 95-128
Fowler, Christopher J
2015
Prostaglandins & other lipid mediators, Elsevier 2015, Vol. 121, (Part B) : 227-233
Gouveia-Figueira, Sandra; Bosson, Jenny A.; Unosson, Jon; et al.
2015
PLoS ONE, Vol. 10, (9)
Gouveia-Figueira, Sandra; Karlsson, Jessica; Deplano, Alessandro; et al.
2015
PLoS ONE, Vol. 10, (4)
Gouveia-Figueira, Sandra; Nording, Malin L.; Gaida, Jamie E.; et al.
2015
PLoS ONE, Vol. 10, (11)
Karlsson, Jessica; Morgillo, Carmine M.; Deplano, Alessandro; et al.
2015
BMC Research Notes, BioMed Central 2015, Vol. 8
Lindgren, Lenita; Gouveia-Figueira, Sandra; Nording, Malin; et al.
2015
PLoS ONE, Vol. 10, (4)
Nicholson, James; Azim, Syed; Rebecchi, Mario J.; et al.
2014
PLoS ONE, Vol. 9, (1) : e87542-
Björklund, Emmelie; Larsson, Therese N. L.; Jacobsson, Stig O. P.; et al.
2014
BMC Research Notes, BioMed Central 2014, Vol. 7 : 441-447
Cipriano, Mariateresa; Gouveia-Figueira, Sandra; Persson, Emma; et al.
2014
TIPS - Trends in Pharmacological Sciences, Vol. 35, (2) : 51-52
Fowler, Christopher J.
2014
PLoS ONE, Public Library Science 2014, Vol. 9, (9)
Hammarsten, Peter; Winther, Johanna; Rudolfsson, Stina H; et al.
2014
Angewandte Chemie International Edition, Wiley-VCH Verlagsgesellschaft 2014, Vol. 53, (50) : 13765-13770
Hernández-Torres, Gloria; Cipriano, Mariateresa; Hedén, Erika; et al.
2014
The Prostate, Vol. 74, (11) : 1107-1117
Häggström, Jenny; Cipriano, Mariateresa; Plym Forshell, Linus; et al.
2014
PLoS ONE, PLOS 2014, Vol. 9, (7) : e103589-
Karlsson, Jessica; Fowler, Christopher
2014
Life Sciences, Elsevier 2014, Vol. 108, (2) : 116-121
Rojo, Maria Luisa; Cipriano, Mariateresa; Söderstrom, Ingegerd; et al.
2014
Journal of Pharmacology and Experimental Therapeutics, Vol. 351, (2) : 457-466
Wheal, Amanda J.; Cipriano, Mariateresa; Fowler, Christopher J.; et al.
2013
European Journal of Pharmacology, Elsevier 2013, Vol. 720, (1-3) : 383-390
Cipriano, Mariateresa; Björklund, Emmelie; Wilson, Alan A.; et al.
2013
PLoS ONE, Vol. 8, (6) : e65798-
Cipriano, Mariateresa; Häggström, Jenny; Hammarsten, Peter; et al.
2013
The FEBS Journal, Vol. 280, (9) : 1895-1904
Fowler, Christopher J.
2013
Journal of enzyme inhibition and medicinal chemistry (Print), Vol. 28, (1) : 172-182
Fowler, Christopher J.; Björklund, Emmelie; Lichtman, Aron H.; et al.
2013
Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids, Vol. 1831, (10) : 1579-1587
Fowler, Christopher J.; Josefsson, Andreas; Thors, Lina; et al.
2013
Journal of Medicinal Chemistry, American Chemical Society (ACS) 2013, Vol. 56, (21) : 8484-8496
Patel, Jayendra Z.; Parkkari, Teija; Laitinen, Tuomo; et al.
2013
Life Sciences, Elsevier 2013, Vol. 92, (13) : 757-762
Rojo, Maria Luisa; Söderström, Ingegerd; Olsson, Tommy; et al.

Research projects