The focus of our research is the evolution of protein function and structure. We’re interested in how evolutionary analyses can be combined with experimental research to reconstruct functional evolution of proteins, and to generate testable hypotheses about unknown aspects of protein function.
Ongoing projects in the group:
Evolution and function of ABCF translation and antibiotic resistance factors in eukaryotes and bacteria
Functional diversity of small alarmone (ppGpp) synthetases in bacteria and bacteriophages
Analysis of ribosome profiling data to elucidate the in vivo role of yeast translation factors
Prediction and verification of novel toxin-antitoxin systems
Development of bioinformatics tools for comparative evolutionary sequence analysis