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Svenska
Kristoffer Brännström
Contact
E-mail
kristoffer.brannstrom@umu.se
Phone
Works at
Affiliation
Affiliated as other position at
Department of Medical Biochemistry and Biophysics
Location
KB. A5, Campus, Umeå
Umeå universitet, 901 87 Umeå
Publications
Publications
Research
Research
2020
A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes
Journal of Bacteriology
, American Society for Microbiology 2020, Vol. 202, (11)
Hansen, Sabine; Hall, Michael; Grundström, Christin; et al.
2020
Apolipoprotein E impairs amyloid-β fibril elongation and maturation
The FEBS Journal
, Wiley-Blackwell 2020, Vol. 287, (6) : 1208-1219
Islam, Tohidul; Gharibyan, Anna L.; Golchin, Solmaz A.; et al.
2020
Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization
Journal of the American Chemical Society
, Vol. 142, (6) : 2876-2888
Jamroskovic, Jan; Doimo, Mara; Chand, Karam; et al.
2019
Pyridine-Fused 2-Pyridones via Povarov and A
3
Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding
Journal of Organic Chemistry
, American Chemical Society (ACS) 2019, Vol. 84, (7) : 3887-3903
Singh, Pardeep; Adolfsson, Dan E.; Ådén, Jörgen; et al.
2018
Scanning electron microscopy as a tool for evaluating morphology of amyloid structures formed on surface plasmon resonance chips
Data in Brief
, Elsevier 2018, Vol. 19 : 1166-1170
Brännström, Kristoffer; Gharibyan, Anna L.; Islam, Tohidul; et al.
2018
The Properties of Amyloid-β Fibrils Are Determined by their Path of Formation
Journal of Molecular Biology
, Elsevier 2018, Vol. 430, (13) : 1940-1949
Brännström, Kristoffer; Islam, Tohidul; Gharibyan, Anna L.; et al.
2018
Structure-based design of inhibitors targeting PrfA, the master virulence regulator of
Listeria monocytogenes
Journal of Medicinal Chemistry
, American Chemical Society (ACS) 2018, Vol. 61, (9) : 4165-4175
Kulén, Martina; Lindgren, Marie; Hansen, Sabine; et al.
2018
Transthyretin Interferes with Aβ Amyloid Formation by Redirecting Oligomeric Nuclei into Non-Amyloid Aggregates
Journal of Molecular Biology
, Elsevier 2018, Vol. 430, (17) : 2722-2733
Nilsson, Lina; Pamrén, Annelie; Islam, Tohidul; et al.
2018
Amyloid-beta 1-40 is associated with alterations in NG2+ pericyte population ex vivo and in vitro
Aging Cell
, John Wiley & Sons 2018, Vol. 17, (3)
Schultz, Nina; Brännström, Kristoffer; Byman, Elin; et al.
2018
Interspecies variation between fish and human transthyretins in their binding of thyroid-disrupting chemicals
Environmental Science and Technology
, American Chemical Society (ACS) 2018, Vol. 52, (20) : 11865-11874
Zhang, Jin; Grundström, Christin; Brännström, Kristoffer; et al.
2017
The role of histidines in amyloid β fibril assembly
FEBS Letters
, Vol. 591, (8) : 1167-1175
Brännström, Kristoffer; Islam, Tohidul; Sandblad, Linda; et al.
2017
Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence
Cell Host and Microbe
, CELL PRESS 2017, Vol. 21, (3) : 376-389
Bugaytsova, Jeanna A.; Björnham, Oscar; Chernov, Yevgen A.; et al.
2016
Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer
PLOS ONE
, Public Library Science 2016, Vol. 11, (4)
Iakovleva, Irina; Begum, Afshan; Brännström, Kristoffer; et al.
2016
Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori
Cell Host and Microbe
, Vol. 19, (1) : 55-66
Moonens, Kristof; Gideonsson, Pär; Subedi, Suresh; et al.
2016
Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity
PLOS ONE
, Public Library Science 2016, Vol. 11, (4)
Nilsson, Lina; Larsson, Andreas; Begum, Afshan; et al.
2016
Structure-based Virtual Screening Protocol for
in silico
Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin
Environmental Science and Technology
, Vol. 50, (21) : 11984-11993
Zhang, Jin; Begum, Afshan; Brännström, Kristoffer; et al.
2015
Enthalpic Forces Correlate with Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma
Journal of Medicinal Chemistry
, Vol. 58, (16) : 6507-6515
Iakovleva, Irina; Brännström, Kristoffer; Nilsson, Lina; et al.
2015
Diversity in Overall Activity Regulation of Ribonucleotide Reductase
Journal of Biological Chemistry
, Vol. 290, (28) : 17339-17348
Jonna, Venkateswara Rao; Crona, Mikael; Rofougaran, Reza; et al.
2015
Biochemical and redox characterization of the mediator complex and its associated transcription factor GeBPL, a GLABROUS1 enhancer binding protein
Biochemical Journal
, Vol. 468, (3) : 385-400
Shaikhali, Jehad; Davoine, Celine; Brännström, Kristoffer; et al.
2014
Interaction Studies of the Human and
Arabidopsis thaliana
Med25-ACID Proteins with the Herpes Simplex Virus VP16-and Plant-Specific Dreb2a Transcription Factors
PLOS ONE
, Vol. 9, (5) : e98575-
Aguilar, Ximena; Blomberg, Jeanette; Brännström, Kristoffer; et al.
2014
A Generic Method for Design of Oligomer-Specific Antibodies
PLOS ONE
, Vol. 9, (3) : e90857-
Brännström, Kristoffer; Lindhagen-Persson, Malin; Gharibyan, Anna L.; et al.
2014
The N-terminal Region of Amyloid β Controls the Aggregation Rate and Fibril Stability at Low pH Through a Gain of Function Mechanism
Journal of the American Chemical Society
, American Chemical Society (ACS) 2014, Vol. 136, (31) : 10956-10964
Brännström, Kristoffer; Öhman, Anders; Nilsson, Lina; et al.
2014
A Repetitive DNA Element Regulates Expression of the
Helicobacter pylori
Sialic Acid Binding Adhesin by a Rheostat-like Mechanism
PLoS Pathogens
, Vol. 10, (7)
Åberg, Anna; Gideonsson, Pär; Vallström, Anna; et al.
2013
Ca2+ enhances Aβ polymerization rate and fibrillar stability in a dynamic manner
Biochemical Journal
, Portland Press 2013, Vol. 450 : 189-197
Brännström, Kristoffer; Öhman, Anders; Lindhagen-Persson, Malin; et al.
2013
Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence
Open Biology
, The Royal Society Publishing 2013, Vol. 3, (10)
Mahdavi, Jafar; Royer, Pierre-Joseph; Sjölinder, Hong S.; et al.
2013
Reconstitution of the anti-apoptotic bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic bax protein
PLOS ONE
, PLoS ONE 2013, Vol. 8, (4)
Wallgren, Marcus; Lidman, Martin; Pedersen, Anders; et al.
2013
Structural topology and activation of an initial adenylate kinase-substrate complex
Biochemistry
, Vol. 52, (6) : 1055-1061
Ådén, Jörgen; Weise, Christoph; Brännström, Kristoffer; et al.
2012
Interactions between DNA, transcriptional regulator Dreb2a and the Med25 mediator subunit from Arabidopsis thaliana involve conformational changes
Nucleic Acids Research
, Oxford: Oxford University Press 2012, Vol. 40, (13) : 5938-5950
Blomberg, Jeanette; Aguilar, Ximena; Brännström, Kristoffer; et al.
2012
Characterization of SPINK9, a KLK5-specific inhibitor expressed in palmo-plantar epidermis
Biological chemistry (Print)
, Walter de Gruyter 2012, Vol. 393, (5) : 369-377
Brännström, Kristoffer; Öhman, Anders; von Pawel-Rammingen, Ulrich; et al.
2012
The C-terminal repeating units of CsgB direct bacterial functional amyloid nucleation
Journal of Molecular Biology
, Elsevier 2012, Vol. 422, (3) : 376-389
Hammer, Neal D; McGuffie, Bryan A; Zhou, Yizhou; et al.
2012
Promiscuous cross-seeding between bacterial amyloids promotes interspecies biofilms
Journal of Biological Chemistry
, ROCKVILLE PIKE, BETHESDA, MD: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 2012, Vol. 287, (42) : 35092-35103
Zhou, Yizhou; Smith, Daniel; Leong, Bryan J; et al.
2011
Aβ peptide fibrillar architectures controlled by conformational constraints of the monomer
PLOS ONE
, San Francisco, CA: Public Library of Science 2011, Vol. 6, (9) : e25157-
Brännström, Kristoffer; Öhman, Anders; Olofsson, Anders
2011
The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 108, (20) : 8245-8250
Elfving, Nils; Davoine, Céline; Benlloch, Reyes; et al.
2011
Structural basis of signal-sequence recognition by the signal recognition particle
Nature Structural & Molecular Biology
, Vol. 18, (3) : 389-391
Hainzl, Tobias; Huang, Shenghua; Meriläinen, Gitte; et al.
2011
Clicked tacrine conjugates as acetylcholinesterase and β-amyloid directed compounds
Organic and biomolecular chemistry
, The Royal Society of Chemistry 2011, Vol. 9, (4) : 1140-1147
Ouberai, Myriam; Brännström, Kristoffer; Vestling, Monika; et al.
2010
Amyloid-β oligomer specificity mediated by the IgM isotype: implications for a specific protective mechanism exerted by endogenous auto-antibodies
PLOS ONE
, Public Library of Science 2010, Vol. 5, (11) : e13928-
Lindhagen-Persson, Malin; Brännström, Kristoffer; Vestling, Monika; et al.
2009
The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling.
Infection and Immunity
, Vol. 77, (3) : 1144-1154
Brännström, Kristoffer; Sellin, Mikael E; Holmfeldt, Per; et al.
2007
Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on sigma54.
Journal of Biological Chemistry
, Vol. 282, (25) : 18046-56
Szalewska-Palasz, Agnieszka; Johansson, Linda U M; Bernardo, Lisandro M D; et al.
2006
Aneugenic activity of Op18/stathmin is potentiated by the somatic Q18-->e mutation in leukemic cells.
Mol Biol Cell
, Vol. 17, (7) : 2921-2930
Holmfeldt, Per; Brännström, Kristoffer; Stenmark, Sonja; et al.
Design of oligomer-specific antibodies
Brännström, Kristoffer; Lindhagen Persson, Malin; Gharabyan, A; et al.
pH regulated
H. pylori
adherence: implications for persistent infection and disease
Bugaytsova, Jeanna; Björnhamn, Oscar; Henriksson, Sara; et al.
Acid Responsive
Helicobacter pylori
Adherence: Implications for Chronic Infection and Disease
Bugaytsova, Jeanna; Chernov, Yevgen A; Gideonsson, Pär; et al.
Clinical isolates of
Helicobacter pylori
demonstrates alternative BabA-mediated adherence to human gastric mucosa
Henriksson, Sara; Mendez, Melissa; Bugaytsova, Jeanna; et al.
The
Helicobacter pylori
sialic acid binding adhesin SabA is regulated via a network of two-component systems
Åberg, Anna; Gideonsson, Pär; Brännström, Kristoffer; et al.
View publications in DiVA
Research groups
Group member
Thomas Borén lab
Research projects
17 January 2007 until 31 December 2008
Molecular dissection of divergent members of a new class of regulators of microtubule dynamics
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