Kristoffer Brännström

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Affiliated as other position at Department of Medical Biochemistry and Biophysics

KB. A5, Campus, Umeå Umeå universitet, 901 87 Umeå

A Novel Growth-Based Selection Strategy Identifies New Constitutively Active Variants of the Major Virulence Regulator PrfA in Listeria monocytogenes

Journal of Bacteriology, American Society for Microbiology 2020, Vol. 202, (11)

Hansen, Sabine; Hall, Michael; Grundström, Christin; et al.

Apolipoprotein E impairs amyloid-β fibril elongation and maturation

The FEBS Journal, Wiley-Blackwell 2020, Vol. 287, (6) : 1208-1219

Islam, Tohidul; Gharibyan, Anna L.; Golchin, Solmaz A.; et al.

Quinazoline Ligands Induce Cancer Cell Death through Selective STAT3 Inhibition and G-Quadruplex Stabilization

Journal of the American Chemical Society, Vol. 142, (6) : 2876-2888

Jamroskovic, Jan; Doimo, Mara; Chand, Karam; et al.

Pyridine-Fused 2-Pyridones via Povarov and A³ Reactions: Rapid Generation of Highly Functionalized Tricyclic Heterocycles Capable of Amyloid Fibril Binding

Journal of Organic Chemistry, American Chemical Society (ACS) 2019, Vol. 84, (7) : 3887-3903

Singh, Pardeep; Adolfsson, Dan E.; Ådén, Jörgen; et al.

Scanning electron microscopy as a tool for evaluating morphology of amyloid structures formed on surface plasmon resonance chips

Data in Brief, Elsevier 2018, Vol. 19 : 1166-1170

Brännström, Kristoffer; Gharibyan, Anna L.; Islam, Tohidul; et al.

The Properties of Amyloid-β Fibrils Are Determined by their Path of Formation

Journal of Molecular Biology, Elsevier 2018, Vol. 430, (13) : 1940-1949

Brännström, Kristoffer; Islam, Tohidul; Gharibyan, Anna L.; et al.

Structure-based design of inhibitors targeting PrfA, the master virulence regulator of Listeria monocytogenes

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2018, Vol. 61, (9) : 4165-4175

Kulén, Martina; Lindgren, Marie; Hansen, Sabine; et al.

Transthyretin Interferes with Aβ Amyloid Formation by Redirecting Oligomeric Nuclei into Non-Amyloid Aggregates

Journal of Molecular Biology, Elsevier 2018, Vol. 430, (17) : 2722-2733

Nilsson, Lina; Pamrén, Annelie; Islam, Tohidul; et al.

Amyloid-beta 1-40 is associated with alterations in NG2+ pericyte population ex vivo and in vitro

Aging Cell, John Wiley & Sons 2018, Vol. 17, (3)

Schultz, Nina; Brännström, Kristoffer; Byman, Elin; et al.

Interspecies variation between fish and human transthyretins in their binding of thyroid-disrupting chemicals

Environmental Science and Technology, American Chemical Society (ACS) 2018, Vol. 52, (20) : 11865-11874

Zhang, Jin; Grundström, Christin; Brännström, Kristoffer; et al.

The role of histidines in amyloid β fibril assembly

FEBS Letters, Vol. 591, (8) : 1167-1175

Brännström, Kristoffer; Islam, Tohidul; Sandblad, Linda; et al.

Helicobacter pylori Adapts to Chronic Infection and Gastric Disease via pH-Responsive BabA-Mediated Adherence

Cell Host and Microbe, CELL PRESS 2017, Vol. 21, (3) : 376-389

Bugaytsova, Jeanna A.; Björnham, Oscar; Chernov, Yevgen A.; et al.

Tetrabromobisphenol A Is an Efficient Stabilizer of the Transthyretin Tetramer

PLOS ONE, Public Library Science 2016, Vol. 11, (4)

Iakovleva, Irina; Begum, Afshan; Brännström, Kristoffer; et al.

Structural Insights into Polymorphic ABO Glycan Binding by Helicobacter pylori

Cell Host and Microbe, Vol. 19, (1) : 55-66

Moonens, Kristof; Gideonsson, Pär; Subedi, Suresh; et al.

Modifications of the 7-Hydroxyl Group of the Transthyretin Ligand Luteolin Provide Mechanistic Insights into Its Binding Properties and High Plasma Specificity

PLOS ONE, Public Library Science 2016, Vol. 11, (4)

Nilsson, Lina; Larsson, Andreas; Begum, Afshan; et al.

Structure-based Virtual Screening Protocol for in silico Identification of Potential Thyroid Disrupting Chemicals Targeting Transthyretin

Environmental Science and Technology, Vol. 50, (21) : 11984-11993

Zhang, Jin; Begum, Afshan; Brännström, Kristoffer; et al.

Enthalpic Forces Correlate with Selectivity of Transthyretin-Stabilizing Ligands in Human Plasma

Journal of Medicinal Chemistry, Vol. 58, (16) : 6507-6515

Iakovleva, Irina; Brännström, Kristoffer; Nilsson, Lina; et al.

Diversity in Overall Activity Regulation of Ribonucleotide Reductase

Journal of Biological Chemistry, Vol. 290, (28) : 17339-17348

Jonna, Venkateswara Rao; Crona, Mikael; Rofougaran, Reza; et al.

Biochemical and redox characterization of the mediator complex and its associated transcription factor GeBPL, a GLABROUS1 enhancer binding protein

Biochemical Journal, Vol. 468, (3) : 385-400

Shaikhali, Jehad; Davoine, Celine; Brännström, Kristoffer; et al.

Interaction Studies of the Human and Arabidopsis thaliana Med25-ACID Proteins with the Herpes Simplex Virus VP16-and Plant-Specific Dreb2a Transcription Factors

PLOS ONE, Vol. 9, (5) : e98575-

Aguilar, Ximena; Blomberg, Jeanette; Brännström, Kristoffer; et al.

A Generic Method for Design of Oligomer-Specific Antibodies

PLOS ONE, Vol. 9, (3) : e90857-

Brännström, Kristoffer; Lindhagen-Persson, Malin; Gharibyan, Anna L.; et al.

The N-terminal Region of Amyloid β Controls the Aggregation Rate and Fibril Stability at Low pH Through a Gain of Function Mechanism

Journal of the American Chemical Society, American Chemical Society (ACS) 2014, Vol. 136, (31) : 10956-10964

Brännström, Kristoffer; Öhman, Anders; Nilsson, Lina; et al.

A Repetitive DNA Element Regulates Expression of the Helicobacter pylori Sialic Acid Binding Adhesin by a Rheostat-like Mechanism

PLoS Pathogens, Vol. 10, (7)

Åberg, Anna; Gideonsson, Pär; Vallström, Anna; et al.

Ca2+ enhances Aβ polymerization rate and fibrillar stability in a dynamic manner

Biochemical Journal, Portland Press 2013, Vol. 450 : 189-197

Brännström, Kristoffer; Öhman, Anders; Lindhagen-Persson, Malin; et al.

Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence

Open Biology, The Royal Society Publishing 2013, Vol. 3, (10)

Mahdavi, Jafar; Royer, Pierre-Joseph; Sjölinder, Hong S.; et al.

Reconstitution of the anti-apoptotic bcl-2 protein into lipid membranes and biophysical evidence for its detergent-driven association with the pro-apoptotic bax protein

PLOS ONE, PLoS ONE 2013, Vol. 8, (4)

Wallgren, Marcus; Lidman, Martin; Pedersen, Anders; et al.

Structural topology and activation of an initial adenylate kinase-substrate complex

Biochemistry, Vol. 52, (6) : 1055-1061

Ådén, Jörgen; Weise, Christoph; Brännström, Kristoffer; et al.

Interactions between DNA, transcriptional regulator Dreb2a and the Med25 mediator subunit from Arabidopsis thaliana involve conformational changes

Nucleic Acids Research, Oxford: Oxford University Press 2012, Vol. 40, (13) : 5938-5950

Blomberg, Jeanette; Aguilar, Ximena; Brännström, Kristoffer; et al.

Characterization of SPINK9, a KLK5-specific inhibitor expressed in palmo-plantar epidermis

Biological chemistry (Print), Walter de Gruyter 2012, Vol. 393, (5) : 369-377

Brännström, Kristoffer; Öhman, Anders; von Pawel-Rammingen, Ulrich; et al.

The C-terminal repeating units of CsgB direct bacterial functional amyloid nucleation

Journal of Molecular Biology, Elsevier 2012, Vol. 422, (3) : 376-389

Hammer, Neal D; McGuffie, Bryan A; Zhou, Yizhou; et al.

Promiscuous cross-seeding between bacterial amyloids promotes interspecies biofilms

Journal of Biological Chemistry, ROCKVILLE PIKE, BETHESDA, MD: AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC 2012, Vol. 287, (42) : 35092-35103

Zhou, Yizhou; Smith, Daniel; Leong, Bryan J; et al.

Aβ peptide fibrillar architectures controlled by conformational constraints of the monomer

PLOS ONE, San Francisco, CA: Public Library of Science 2011, Vol. 6, (9) : e25157-

Brännström, Kristoffer; Öhman, Anders; Olofsson, Anders

The Arabidopsis thaliana Med25 mediator subunit integrates environmental cues to control plant development

Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, (20) : 8245-8250

Elfving, Nils; Davoine, Céline; Benlloch, Reyes; et al.

Structural basis of signal-sequence recognition by the signal recognition particle

Nature Structural & Molecular Biology, Vol. 18, (3) : 389-391

Hainzl, Tobias; Huang, Shenghua; Meriläinen, Gitte; et al.

Clicked tacrine conjugates as acetylcholinesterase and β-amyloid directed compounds

Organic and biomolecular chemistry, The Royal Society of Chemistry 2011, Vol. 9, (4) : 1140-1147

Ouberai, Myriam; Brännström, Kristoffer; Vestling, Monika; et al.

Amyloid-β oligomer specificity mediated by the IgM isotype: implications for a specific protective mechanism exerted by endogenous auto-antibodies

PLOS ONE, Public Library of Science 2010, Vol. 5, (11) : e13928-

Lindhagen-Persson, Malin; Brännström, Kristoffer; Vestling, Monika; et al.

The Schistosoma mansoni protein Sm16/SmSLP/SmSPO-1 assembles into a nine-subunit oligomer with potential To inhibit Toll-like receptor signaling.

Infection and Immunity, Vol. 77, (3) : 1144-1154

Brännström, Kristoffer; Sellin, Mikael E; Holmfeldt, Per; et al.

Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on sigma54.

Journal of Biological Chemistry, Vol. 282, (25) : 18046-56

Szalewska-Palasz, Agnieszka; Johansson, Linda U M; Bernardo, Lisandro M D; et al.

Aneugenic activity of Op18/stathmin is potentiated by the somatic Q18-->e mutation in leukemic cells.

Mol Biol Cell, Vol. 17, (7) : 2921-2930

Holmfeldt, Per; Brännström, Kristoffer; Stenmark, Sonja; et al.

Design of oligomer-specific antibodies

Brännström, Kristoffer; Lindhagen Persson, Malin; Gharabyan, A; et al.

pH regulated H. pylori adherence: implications for persistent infection and disease

Bugaytsova, Jeanna; Björnhamn, Oscar; Henriksson, Sara; et al.

Acid Responsive Helicobacter pylori Adherence: Implications for Chronic Infection and Disease

Bugaytsova, Jeanna; Chernov, Yevgen A; Gideonsson, Pär; et al.

Clinical isolates of Helicobacter pylori demonstrates alternative BabA-mediated adherence to human gastric mucosa

Henriksson, Sara; Mendez, Melissa; Bugaytsova, Jeanna; et al.

The Helicobacter pylori sialic acid binding adhesin SabA is regulated via a network of two-component systems

Åberg, Anna; Gideonsson, Pär; Brännström, Kristoffer; et al.

View publications in DiVA

Research groups

Group member

Thomas Borén lab

Research projects

17 January 2007 until 31 December 2008

Molecular dissection of divergent members of a new class of regulators of microtubule dynamics