Postdoctoral Position in the Arnberg/Gerold labs
The research groups “Virus-host interactions“ and “Virus Interaction Proteomics” at the Department of Clinical Microbiology, Umeå University, are recruiting a research associate (postdoc) on a 2 year position in virology to pursue a project aiming at elucidating and characterizing host receptors for gastroenteric adenoviruses.
Our groups focus on the study of host attachment factors and receptors for human pathogenic viruses. We use state of the art interaction proteomics methods in conjunction with virology and cell biology techniques to characterize cell surface proteins and glycans bound by viruses.
You will be responsible for carrying out research as part of a collaborative project involving the Arnberg (www.mims.umu.se/groups/niklas-arnberg) and Gerold (www.umu.se/en/staff/gisa-gerold) research groups. The project aims at identifying and characterizing attachment factors and receptors for the short fiber knob component of the adenovirus 41 capsid. Specifically, ligand based receptor capture protocols and co-immunoprecipitation methods will be used. You will further validate and characterize identified host factors by RNA interference, CRISPR/Cas9 technology, surface plasmon resonance and pharmacological perturbation in conjunction with cell culture assays. Gastroenteric adenoviruses are a major public health concern and currently no therapy or vaccine exists to treat or prevent infection.
You will work closely with other postdoctoral researchers in the Arnberg lab to purify adenovirus 41 short fiber knob interacting host proteins. The samples will be used for mass spectrometry based receptor candidate identification by state of the art label free quantification. The design and optimization of these methods as well as data analysis will be done in collaboration with the Gerold lab.
In the first place applicants who have completed a doctoral degree no more than three years before the application deadline are considered. If there are special reasons, an earlier doctoral degree could be considered. Special reasons refer to leave due to illness, parental leave or clinical service, trust assignments within trade union organizations or other similar circumstances”
We are an international team based at the Department of Clinical Microbiology at Umea University, Sweden. Our group has access to state-of-the-art equipment and techniques for cell culture work and mass spectrometry based proteomics. We offer an international, stimulating and collaborative research environment, in which your scientific career development is fostered.
Full time position, two years - start according to agreement.
The application should contain
The application is made electronically (via the system Varbi) - last day to apply is April 15, 2019.
For questions, please contact:
Niklas Arnberg, E-mail: email@example.com
Gisa Gerold, E-mail: firstname.lastname@example.org
Welcome with your application!
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