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Postdoctoral Position: Single cell analysis of malaria parasite development

Institutionen för molekylärbiologi

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before

2019-09-30

  • Type of employment Temporary position longer than 6 months
  • Extent 100%
  • Place Umeå

The Department of Molecular Biology

The department provides a vibrant interfaculty research environment and there is access to a wide range of state-of-the-art imaging, metabolomics, genomics and screening facilities. You will join a research team that is part of the Laboratory for Molecular Infection Medicine Sweden (MIMS), which is internationally well-connected through the European Molecular Biology Laboratory (EMBL) Nordic Partnership for Molecular Medicine.

Project description and work tasks

We are an interdisciplinary team of experimentalists, analysts and modellers, who work together closely to address important questions of malaria parasite development and transmission. We are now looking for an experimental geneticist to develop large scale approaches for phenotyping mutants by single cell transcriptomics, using perturb-seq or CROPseq approaches. Using single cell RNAseq (e.g. Reid et al., eLife, 2018), you will carry out an in-depth analysis of developmental mutants. Using their unique transcriptional signatures you will study genetic networks and mechanisms of parasite development during transmission that can be targeted by new intervention strategies.

The project forms part of a major effort funded by the European Research Council and the Knut and Alice Wallenberg Foundation (KAW) to systematically identify parasite gene functions in malaria transmission.

The position is full time for two years and is placed at the Department of Molecular Biology, Umeå University, Sweden. The position is expected to start in November 2019 or as otherwise agreed. 

Qualifications

Candidates should hold a PhD degree in experimental genetics. You should be experienced in a number of genetic and genomic approaches and you should have worked previously with genome-scale datasets from transcriptomic or proteomic experiments. You should have evidence of a strong relevant research output, as evidenced by first authorship, on publications presenting ground-breaking new research findings or new molecular biology tools. To be eligible you should have completed your PhD degree a maximum of three years before the end of the application period, unless special circumstances exist.

Candidates must be fluent in spoken and written English. Since the project will be of collaborative nature, candidates need to be able to work productively also in a team and therefore have a good ability to co-operate. Excellent communication skills are required for interacting effectively with colleagues and peers, including colleagues from complementary research fields. Good initiative ability is a requirement.

Knowledge of molecular parasitology and rodent models would be an advantage. Evidence of productive work in an interdisciplinary environment would be an advantage. Awareness of single cell technologies would be desirable.

Application

The application should include:

  • A personal cover letter explaining why you are interested in the position, how you can contribute to the project and in which direction you may want to develop it (no more than 2 A4 pages).
  • A curriculum vitae that documents academic education and past and previous employments.
  • Your publication list.
  • A copy of the PhD certificate and other relevant degree certificates.
  • A copy of doctoral thesis
  • Names and contact details with e-mail addresses of two or three academic references.
  • Other relevant documentation you wish to include in support of your application.

The application should be written in English (preferably) or Swedish. You apply through our recruitment system. Log in to the system and apply via the button at the bottom of the webpage. The deadline for application is September 30, 2019.

We look forward to your application!

More about us

More information about The Department of Molecular Biology please visit www.umu.se/en/department-of-molecular-biology/. For additional information, visit our lab page billkerlab.org, or contact Oliver Billker (oliver.billker@umu.se).

Admission

November 2019 or as agreed

Contact

Oliver Billker

oliver.billker@umu.se

Registration number

AN 2.2.1-1062-19

Salary

Monthly salary

Union representative

SACO

090-786 53 65

SEKO

090-786 52 96

ST

090-786 54 31

Apply

before

2019-09-30

Umeå University wants to offer an equal environment where open dialogue between people with different backgrounds and perspectives lay the foundation for learning, creativity and development. We welcome people with different backgrounds and experiences to apply for the current employment. We kindly decline offers of recruitment and advertising help.