Linda Boldrup

Fil Dr i Patologi. Bedriver forskning kring biomarkörer för skivepitelcancer i huvud- och halsområdet.

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Anknuten som övrig/annan befattning till Institutionen för medicinsk biovetenskap Enhet: Patologi

By 6M, vån 2, Sjukhusområdet Umeå universitet, 901 85 Umeå

Fil mag examen i molekylärbiologi vid Umeå universitet. Därefter forskarstudier på institutionen för Medicinsk biovetenskap, Umeå universitet. Disputerade våren 2008 i ämnet Patologi. Sedan fortsatt forskning kring molekylära mekanismer och biomarkörer för skivepitelcancer i huvud- och halsområdet.

Low potential of circulating interleukin 1 receptor antagonist as a prediction marker for squamous cell carcinoma of the head and neck

Journal of Oral Pathology & Medicine, John Wiley & Sons 2021, Vol. 50, (8) : 785-794

Boldrup, Linda; Coates, Philip; Gu, Xiaolian; et al.

High Levels of Low-Density Lipoproteins Correlate with Improved Survival in Patients with Squamous Cell Carcinoma of the Head and Neck

Biomedicines, MDPI 2021, Vol. 9, (5)

Wilms, Torben; Boldrup, Linda; Gu, Xiaolian; et al.

Downregulation of TAP1 in Tumor-Free Tongue Contralateral to Squamous Cell Carcinoma of the Oral Tongue, an Indicator of Better Survival.

International Journal of Molecular Sciences, MDPI 2020, Vol. 21, (17)

Attaran, Nima; Gu, Xiaolian; Coates, Philip J; et al.

Levels of MUC1 in tumours and serum of patients with different sub-types of squamous cell carcinoma of the head and neck

Oncology Letters, Spandidos Publications 2020, Vol. 20, (2) : 1709-1718

Boldrup, Linda; Coates, Philip; Gu, Xiaolian; et al.

Keratin 36, a specific marker of tongue filiform papillae, is downregulated in squamous cell carcinoma of the mobile tongue

Molecular and clinical oncology, Spandidos Publications 2020, Vol. 12, (5) : 421-428

Brychtova, Veronika; Coates, Philip J.; Hrabal, Vaclav; et al.

Transfer-RNA-Derived Fragments Are Potential Prognostic Factors in Patients with Squamous Cell Carcinoma of the Head and Neck

Genes, MDPI 2020, Vol. 11, (11)

Gu, Xiaolian; Wang, Lixiao; Coates, Philip J.; et al.

Comparison of Quality of Life among Patients with Oro-Hypopharyngeal Cancer after Tonsillectomy and Panscopy Using Transoral Robotic Surgery: A Pilot Study

Case Reports in Oncology, S. Karger 2020, Vol. 13, (3) : 1295-1303

Salehi, Amir M.; Norberg-Spaak, Lena; Wilms, Torben; et al.

PD-L1 in squamous cell carcinoma of the oral tongue shows gender-specific association with prognosis

Oral Diseases, John Wiley & Sons 2020, Vol. 26, (7) : 1414-1423

Wilms, Torben; Gu, Xiaolian; Boldrup, Linda; et al.

Altered mRNA Expression of Genes Involved in Endocannabinoid Signalling in Squamous Cell Carcinoma of the Oral Tongue

Cancer Investigation, Vol. 37, (8) : 327-338

Alhouayek, Mireille; Boldrup, Linda; Fowler, Christopher J

High immune cytolytic activity in tumor-free tongue tissue confers better prognosis in patients with squamous cell carcinoma of the oral tongue

The journal of pathology. Clinical research, John Wiley & Sons 2019, Vol. 5, (4) : 240-247

Gu, Xiaolian; Boldrup, Linda; Coates, Philip J.; et al.

Copy number variation: A prognostic marker for young patients with squamous cell carcinoma of the oral tongue

Journal of Oral Pathology & Medicine, John Wiley & Sons 2019, Vol. 48, (1) : 24-30

Gu, Xiaolian; Coates, Philip J.; Boldrup, Linda; et al.

AP001056.1, A Prognosis-Related Enhancer RNA in Squamous Cell Carcinoma of the Head and Neck

Cancers, MDPI 2019, Vol. 11, (3)

Gu, Xiaolian; Wang, Lixiao; Boldrup, Linda; et al.

Searching for new targets and treatments in the battle against squamous cell carcinoma of the head and neck, with specific focus on tumours of the tongue

Current Topics in Medicinal Chemistry, Bentham Science Publishers 2018, Vol. 18, (3) : 214-218

Sgaramella, Nicola; Gu, Xiaolian; Boldrup, Linda; et al.

Ethnicity based variation in expression of E-cadherin in patients with squamous cell carcinoma of the oral tongue

Oncology Letters, Spandidos Publications 2018, Vol. 16, (5) : 6603-6607

Sgaramella, Nicola; Wilms, Torben; Boldrup, Linda; et al.

Gene expression changes in tumor free tongue tissue adjacent to tongue squamous cell carcinoma

OncoTarget, Vol. 8, (12) : 19389-19402

Boldrup, Linda; Gu, Xiaolian; Coates, Philip J.; et al.

Evidence that circulating proteins are more promising than miRNAs for identification of patients with squamous cell carcinoma of the tongue

OncoTarget, IMPACT JOURNALS LLC 2017, Vol. 8, (61) : 103437-103448

Boldrup, Linda; Troiano, Giuseppe; Gu, Xiaolian; et al.

Patients with high c-MYC-expressing squamous cell carcinomas of the tongue show better survival than those with low- and medium-expressing tumours

Journal of Oral Pathology & Medicine, John Wiley & Sons 2017, Vol. 46, (10) : 967-971

Strindlund, Klas; Troiano, Giuseppe; Sgaramella, Nicola; et al.

Expression of the long non-coding RNA HOTAIR as a prognostic factor in squamous cell carcinoma of the head and neck: a systematic review and meta-analysis

OncoTarget, Impact Journals LLC 2017, Vol. 8, (42) : 73029-73036

Troiano, Giuseppe; Caponio, Vito Carlo Alberto; Boldrup, Linda; et al.

Epigenetic regulation of OAS2 shows disease-specific DNA methylation profiles at individual CpG sites

Scientific Reports, Vol. 6

Gu, Xiaolian; Boldrup, Linda; Coates, Philip J; et al.

High expression of podoplanin in squamous cell carcinoma of the tongue occurs predominantly in patients ≤ 40 years but does not correlate with tumour spread

The Journal of Pathology: Clinical Research, John Wiley & Sons 2016, Vol. 2, (1) : 3-8

Sgaramella, Nicola; Lindell Jonsson, Eva; Boldrup, Linda; et al.

Circulating miRNAs from blood, plasma or serum as promising clinical biomarkers in oral squamous cell carcinoma: A systematic review of current findings

Oral Oncology, Vol. 63 : 30-37

Troiano, Giuseppe; Boldrup, Linda; Ardito, Fatima; et al.

Downregulation of miRNA-424: a sign of field cancerisation in clinically normal tongue adjacent to squamous cell carcinoma

British Journal of Cancer, Nature Publishing Group 2015, Vol. 112, (11) : 1760-1765

Boldrup, Linda; Coates, P J; Laurell, G; et al.

Wilms' tumor gene 1 regulates p63 and promotes cell proliferation in squamous cell carcinoma of the head and neck

BMC Cancer, Vol. 15

Li, Xingru; Ottosson, Sofia; Wang, Sihan; et al.

Autoantibodies and decreased expression of the transcription factor ELF-3 together with increased chemokine pathways support an autoimmune phenotype and altered differentiation in lichen planus located in oral mucosa

Journal of the European Academy of Dermatology and Venereology, Wiley-Blackwell 2013, Vol. 27, (11) : 1410-1416

Danielsson, Karin; Boldrup, Linda; Rentoft, Matilda; et al.

Reply to increased levels of COX-2 and oral lichen planus by P.D. Pigatto, F. Spaderi, G.P. Bombeccari, G. Guzzi by Danielsson et al

Journal of the European Academy of Dermatology and Venereology, Wiley-Blackwell 2013, Vol. 27, (3) : 395-396

Danielsson, Karin; Ebrahimi, Majid; Wahlin, Ylva-Britt; et al.

p63 transcriptionally regulates BNC1, a Pol I and Pol II transcription factor that regulates ribosomal biogenesis and epithelial differentiation

European Journal of Cancer, Elsevier 2012, Vol. 48, (9) : 1401-1406

Boldrup, Linda; Coates, Philip J; Laurell, Göran; et al.

Subsite-based alterations in miR-21, miR-125b, and miR-203 in squamous cell carcinoma of the oral cavity and correlation to important target proteins.

Journal of Carcinogenesis, National Center for Biotechnology Information, USA 2012, Vol. 11 : 18-

Boldrup, Linda; Coates, Philip J; Wahlgren, Magnus; et al.

Increased levels of COX-2 in oral lichen planus supports an autoimmune cause of the disease

Journal of the European Academy of Dermatology and Venereology, Wiley-Blackwell 2012, Vol. 26, (11) : 1415-1419

Danielsson, Karin; Ebrahimi, Maijd; Wahlin, Ylva-Britt; et al.

Decreased expression of ELF-3 indicating disturbed differentiation in oral lichen planus

Oral Diseases, Wiley-Blackwell 2012, Vol. 18, (Special Issue, Suppl. 1) : 20-20

Danielsson, Karin; Wahlin, Ylva-Britt; Boldrup, Linda; et al.

Altered expression of miR-21, miR-125b, and miR-203 indicates a role for these microRNAs in oral lichen planus

Journal of Oral Pathology & Medicine, Vol. 41, (1) : 90-95

Danielsson, Karin; Wahlin, Ylva-Britt; Gu, Xiaolian; et al.

Changes in miRNA expression in sera and correlation to duration of disease in patients with multifocal mucosal lichen planus.

Journal of Oral Pathology & Medicine, Wiley 2012, Vol. 41, (1) : 86-89

Nylander, Elisabet; Ebrahimi, Majid; Wahlin, Ylva-Britt; et al.

Differences in p63 expression in SCCHN tumours of different sub-sites within the oral cavity

Oral Oncology, Elsevier 2011, Vol. 47, (9) : 861-865

Boldrup, Linda; Coates, Philip J; Laurell, Göran; et al.

DeltaNp63 isoforms differentially regulate gene expression in squamous cell carcinoma: identification of Cox-2 as a novel p63 target.

The Journal of pathology

Boldrup, Linda; Coates, Philip J; Gu, Xiaolian; et al.

p63 contributes to cell invasion and migration in squamous cell carcinoma of the head and neck

Cancer Letters, Vol. 263, (1) : 26-34

Gu, Xiaolian; Coates, Philip J; Boldrup, Linda; et al.

Expression of p53 isoforms in squamous cell carcinoma of the head and neck.

Eur J Cancer, Vol. 43, (3) : 617-23

Boldrup, Linda; Bourdon, Jean-Christophe; Coates, Philip J; et al.

DeltaNp63 isoforms regulate CD44 and keratins 4, 6, 14 and 19 in squamous cell carcinoma of head and neck.

J Pathol, Vol. 213, (4) : 384-91

Boldrup, Linda; Coates, Philip J; Gu, Xiaolian; et al.

Expression of novel p53 isoforms in oral lichen planus.

Oral Oncology, Vol. 44, (2) : 156-161

Ebrahimi, Majid; Boldrup, Linda; Coates, Philip J; et al.

Decreased expression of the p63 related proteins beta-catenin, E-cadherin and EGFR in oral lichen planus

Oral Oncology, Elsevier 2007, Vol. 44, (7) : 634-638

Ebrahimi, Majid; Boldrup, Linda; Wahlin, Ylva-Britt; et al.

TRAF4 is potently induced by TAp63 isoforms and localised according to differentiation in SCCHN

Cancer Biology & Therapy, Vol. 6, (12) : 1979-1983

Gu, Xiaolian; Coates, Philip; MacCallum, Stephanie; et al.

Expression of p63, COX-2, EGFR and beta-catenin in smokers and patients with squamous cell carcinoma of the head and neck reveal variations in non-neoplastic tissue and no obvious changes in smokers.

International Journal of Oncology, Vol. 27, (6) : 1661-1667

Boldrup, Linda; Coates, Philip J; Hedberg, Ylva; et al.

Function and importance of p63 in normal oral mucosa and squamous cell carcinoma of the head and neck.

Advances in Oto-Rhino-Laryngology, Vol. 62 : 49-57

Thurfjell, Niklas; Coates, Philip J; Boldrup, Linda; et al.

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