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Weixing Qian
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weixing.qian@umu.se
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090-786 88 54
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KB.C4, Linnaeus väg 10
Umeå universitet, 901 87 Umeå
Publikationer
Publikationer
2022
Structural Modifications and Biological Evaluations of Rift Valley Fever Virus Inhibitors Identified from Chemical Library Screening
ACS Omega
, American Chemical Society (ACS) 2022, Vol. 7, (8) : 6854-6868
Islam, Koushikul; Carlsson, Marcus; Enquist, Per-Anders; et al.
2021
Identification of a novel compound that simultaneously impairs the ubiquitin-proteasome system and autophagy
Autophagy
Giovannucci, Tatiana A.; Salomons, Florian A.; Stoy, Henriette; et al.
2020
Pentavalent Sialic Acid Conjugates Block Coxsackievirus A24 Variant and Human Adenovirus Type 37-Viruses That Cause Highly Contagious Eye Infections
ACS Chemical Biology
, American Chemical Society (ACS) 2020, Vol. 15, (10) : 2683-2691
Johansson, Emil; Caraballo, Remi; Mistry, Nitesh; et al.
2020
Optimization of Tetrahydroindazoles as Inhibitors of Human Dihydroorotate Dehydrogenase and Evaluation of Their Activity and In Vitro Metabolic Stability
Journal of Medicinal Chemistry
, American Chemical Society (ACS) 2020, Vol. 63, (8) : 3915-3934
Popova, Gergana; Ladds, Marcus J. G. W.; Johansson, Lars; et al.
2019
Interaction between VPS35 and RABG3f is necessary as a checkpoint to control fusion of late compartments with the vacuole
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 116, (42) : 21291-21301
Rodriguez-Furlan, Cecilia; Domozych, David; Qian, Weixing; et al.
2018
Screening for Inhibitors of Acetaldehyde Dehydrogenase (AdhE) from Enterohemorrhagic Escherichia coli (EHEC)
SLAS Discovery
, Sage Publications 2018, Vol. 23, (8) : 815-822
Zetterström, Caroline E.; Uusitalo, Pia; Qian, Weixing; et al.
2015
Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase
Journal of Computer-Aided Molecular Design
, Vol. 29, (3) : 199-215
Andersson, C. David; Hillgren, J. Mikael; Lindgren, Cecilia; et al.
2015
Structure-activity relationships for lipoprotein lipase agonists that lower plasma triglycerides
in vivo
European Journal of Medicinal Chemistry
, Elsevier 2015, Vol. 103 : 191-209
Caraballo, Remi; Larsson, Mikael; Nilsson, Stefan K.; et al.
2015
Triazole linker-based trivalent sialic acid inhibitors of adenovirus type 37 infection of human corneal epithelial cells
Organic and biomolecular chemistry
, Vol. 13, (35) : 9194-9205
Caraballo, Rémi; Saleeb, Michael; Bauer, Johannes; et al.
2013
Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors
Journal of Medicinal Chemistry
, American Chemical Society (ACS) 2013, Vol. 56, (19) : 7615-7624
Andersson, C. David; Forsgren, Nina; Akfur, Christine; et al.
2012
Similar but Different: Thermodynamic and Structural Characterization of a Pair of Enantiomers Binding to Acetylcholinesterase
Angewandte Chemie International Edition
, Vol. 51, (51) : 12716-12720
Berg, Lotta; Niemiec, Moritz S.; Qian, Weixing; et al.
2011
A Potent Trivalent Sialic Acid Inhibitor of Adenovirus Type 37 Infection of Human Corneal Cells
Angewandte Chemie International Edition
, Wiley 2011, Vol. 50, (29) : 6519-6521
Spjut, Sara; Qian, Weixing; Bauer, Johannes; et al.
2010
Synthesis and application of a 2-[(4-fluorophenyl)sulfonyl]ethoxy carbonyl (Fsec) protected glycosyl donor in carbohydrate chemistry
Molecules
, Vol. 15, (8) : 5708-5720
Spjut, Sara; Qian, Weixing; Elofsson, Mikael
2009
Design, synthesis, and evaluation of N-acyl modified sialic acids as inhibitors of adenoviruses causing epidemic keratoconjunctivitis
Journal of Medicinal Chemistry
, Vol. 52, (12) : 3666-3678
Johansson, Susanne; Nilsson, Emma; Qian, Weixing; et al.
2009
Synthesis and application of N-[1-(4-(4-fluorophenyl)-2,6-dioxocyclohexylidene)ethyl] (Fde)-protected amino acids for optimization of solid-phase peptide synthesis using gel-phase (19)F NMR spectroscopy.
Journal of Peptide Science
, European Peptide Society and John Wiley & Sons, Ltd. 2009, Vol. 15, (4) : 264-71
Pudelko, Maciej; Qian, Weixing; Elofsson, Mikael
Design, synthesis and evaluation of N-acyl modified sialic acids as inhibitors of EKC-causing adenoviruses
Johansson, Susanne; Nilsson, Emma; Qian, Weixing; et al.
Design of Reactive Drugs: Structure and Mechanism of Novel Nerve Agent Antidotes
Lindgren, Cecilia; Forsgren, Nina; Akfur, Christine; et al.
Synthesis and evaluation of tri- and tetravalent sialic acid inhibitors of EKC-causing adenoviruses
Spjut, Sara; Qian, Weixing; Bauer, Johannes; et al.
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