Main Field of Study and progress level:
Chemistry: Second cycle, in-depth level of the course cannot be classified
Grading scale: Pass with distinction, Pass, Fail
Responsible department: Department of Chemistry
Contents
The goal of the course is to give basic knowledge in the area of medicinal chemistry. This includes knowledge in interactions between low molecular weight compounds and proteins, DNA, and RNA, and methods for identification, design, synthesis, and evaluation of drug candidates. The laboratory part of the course includes design, synthesis and evaluation of biologically active compounds.
After completion of the course the students shall be familiar with the processes involved in the development of a drug, have a detailed understanding of the concept of ligand-receptor interaction, possess basic knowledge in methods for medicinal and combinatorial chemistry, have a broad overview of drug uptake, metabolism, and secretion, and by oneself be able to retrieve chemical, biological, and medical information from databases, and have practical skills in design, synthesis, and evaluation of biologically active compounds.
Required Knowledge
Bioorganic Chemistry (15 credits 5KE010 ) and Biochemistry (15 credits 5KE057) or the equivalent. The course can not be combined with Theoretical Medicinal Chemistry 7,5 credits, Medicinal Chemistry 7,5 credits or Applied Medicinal Chemistry 7,5 credits
English proficiency equivalent to IELTS Academic Training minimum score 5.0 with no individual score below 4.5 (Tests taken before January 2005 not admissible or TOEFL minimum score 500 on paper based test and not below 4.0 on the TWE, Alternatively 173 on computer based test with iBT61 is also required as well as basic entrance requirements for higher studies in Swedish language proficiency if the course in taught in Swedish.
Literature
Valid from:
2007 week 27
Patrick Graham L. An introduction to medicinal chemistry 3. ed. : Oxford : Oxford University Press : 2005 : 741 s. : ISBN: 0-19-927500-9 (hft.) Search the University Library catalogue
