Services of the X-ray Diffraction Facility (XRDF)

The services provided by the X-ray Diffraction Facility (XRDF) include:

• Screening of crystallization conditions using the nano-drop pipetting robot (mosquito®)
• Monitoring, evaluation and scoring of crystallization screens
• Optimization of initial screens
• Diffractions tests and iterative crystal optimization (diffraction quality and resolution)
• Full diffraction data collection incl. data processing and data analysis
• X-ray crystal structure determination, refinement and validation
• Deposition of coordinates with the Protein Data Bank (PDB) or the Cambridge Structural Database (CSD)
• Compound screens: co-crystallization with fragments and compounds (in collaboration with LCBU)
• Cryogenic preservation of crystals (vitrification) and storage in liquid nitrogen
• Powder data collection