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Staff photo Constantin Urban

Constantin Urban

I explore innate immune responses against microbial pathogens. Our team aims to exploit new immunological insight to develop new diagnostic tools and antimicrobial therapies.

Works at

Professor at Department of Clinical Microbiology Units: Immunology, Section of Infection and Immunology
Universitetssjukhuset by 6M, Department of Clinical Microbiology, Immunology, Plan 4 Umeå universitet, 901 85 Umeå

I am a Professor in immunology at the Department of Clinical Microbiology. I lead a dedicated research team studying the innate immune system, such as granulocytic neutrophils, mast cells and dendritic cells. Using a variety of immunological, biochemical and imaging techniques, we aim to elucidate how these innate immune cells recognize and combat microbial pathogens, namely viruses, bacteria and fungal organisms. In doing so, our ultimate goal is to apply fundamental knowledge gained from studies of immune mechanisms to identify new strategies for more accurate diagnostic tools and for improved antimicrobial therapies.

The foundation of independent research was formed by my PhD thesis work on cell wall proteins of the human fungal pathogen Candida albicans (University of Stuttgart, Germany) and a postdoctoral fellowship conducted at the Max Planck Institute for Infection Biology (Berlin, Germany), where I studied innate immune responses to microbial pathogens.

In 2009, I was recruited as a group leader to the then newly formed Laboratory for Molecular Infection Medicine Sweden (MIMS) located at the Department of Molecular Biology and in 2012 I started a tenure-track position funded by the Medical Faculty as a preclinical researcher in a clinical environment at the Department of Clinical Microbiology.

Jornal Brasileiro de Nefrologia, FapUNIFESP (SciELO) 2021, Vol. 43, (3) : 431-433
Poloni, José Antonio Tesser; Garcia, Clotilde Druck; Rotta, Liane Nanci; et al.
Frontiers in Immunology, Frontiers Media S.A. 2021, Vol. 12
Shankar, Madhu; Uwamahoro, Nathalie; Backman, Emelie; et al.
Frontiers in Chemistry, Frontiers Media S.A. 2021, Vol. 9
Shchukarev, Andrey; Backman, Emelie; Watts, Samuel; et al.
Current Opinion in Microbiology, Elsevier 2020, Vol. 58 : 106-115
Urban, Constantin F.; Backman, Emelie
Frontiers in Microbiology, Vol. 10
Hosseinzadeh, Ava; Stylianou, Marios; Lopes, Jose Pedro; et al.
Bio-protocol, Bio-Protocol 2019, Vol. 9, (15)
Lopes, Jose Pedro; Urban, Constantin F.
Frontiers in Cellular and Infection Microbiology, Frontiers Media S.A. 2019, Vol. 9
Lopes, José Pedro; Stylianou, Marios; Backman, Emelie; et al.
British Journal of Cancer, Nature Publishing Group 2019, Vol. 120, (2) : 207-217
Singel, Kelly L.; Grzankowski, Kassondra S.; Khan, A. N. M. Nazmul H.; et al.
Seminars in Cell and Developmental Biology, Elsevier 2019, Vol. 89 : 47-57
Urban, Constantin F.; Nett, Jeniel E
PLoS Pathogens, PUBLIC LIBRARY SCIENCE 2018, Vol. 14, (5)
Crawford, Aaron C.; Lehtovirta-Morley, Laura E.; Alamir, Omran; et al.
Inflammation: fundamental mechanisms, World Scientific 2018 : 205-275
Fuchs, Tobias A.; Hakkim, Abdul; Urban, Constantin F.
mBio, American Society for Microbiology 2018, Vol. 9, (6)
Lopes, Jose Pedro; Stylianou, Marios; Backman, Emelie; et al.
Frontiers in Immunology, Frontiers Media S.A. 2018, Vol. 9
Thunström Salzer, Anna; Niemiec, Maria Joanna; Hosseinzadeh, Ava; et al.
Medical Imaging 2017: Digital Pathology
Ginley, Brandon; Emmons, Tiffany; Sasankan, Prabhu; et al.
Scientific Reports, Nature Publishing Group 2017, Vol. 7, (1)
Ginley, Brandon G; Emmons, Tiffany; Lutnick, Brendon; et al.
BMC Genomics, Vol. 18
Niemiec, Maria Joanna; Grumaz, Christian; Ermert, David; et al.
Journal of Leukocyte Biology, Vol. 100, (5) : 1105-1112
Hosseinzadeh, Ava; Thompson, Paul R.; Segal, Brahm H.; et al.
Microbes and infection, Vol. 17, (5) : 327-336
Gillenius, Erik; Urban, Constantin F
Scientific Reports, Nature Publishing Group 2015, Vol. 5
Lopes, Jose Pedro; Stylianou, Marios; Nilsson, Gunnar; et al.
Metallomics, Vol. 7, (6) : 996-1010
Niemiec, Maria Joanna; De Samber, B.; Garrevoet, J.; et al.
Journal of Biomolecular Screening, Vol. 20, (2) : 285-91
Stylianou, Marios; Uvell, Hanna; Lopes, Jose Pedro; et al.
Scandinavian Journal of Immunology, Vol. 79, (6) : 432-432
Bjornsdottir, Halla; Christenson, Karin; Forsman, Huamei; et al.
Infection and Immunity, Vol. 82, (5) : 1766-1777
Röhm, Marc; Grimm, Melissa J.; D'Auria, Anthony C.; et al.
Antimicrobial Agents and Chemotherapy, Vol. 58, (2) : 1055-1062
Stylianou, Marios; Kulesskiy, Evgeny; Lopes, José Pedro; et al.
Frontiers in Immunology, Vol. 4
Almyroudis, Nikolaos G.; Grimm, Melissa J.; Davidson, Bruce A.; et al.
Journal of Leukocyte Biology, Bethesda: Federation of American societies for experimental biology 2013, Vol. 94, (2) : 223-236
Ermert, David; Niemiec, Maria Joanna; Röhm, Marc; et al.
Journal of Immunology, Vol. 190, (8) : 4175-4184
Grimm, Melissa J; Vethanayagam, R Robert; Almyroudis, Nikolaos G; et al.
PLOS ONE, Vol. 8, (10)
Hosseinzadeh, Ava; Urban, Constantin F.
Molecular Microbiology, Vol. 87, (1) : 132-151
Röhm, Marc; Lindemann, E.; Hiller, E.; et al.
PLoS Pathogens, Vol. 9, (9)
Seper, Andrea; Hosseinzadeh, Ava; Gorkiewicz, Gregor; et al.
Infection and Immunity, Vol. 81, (1) : 11-22
Thorslund, Sara E; Ermert, David; Fahlgren, Anna; et al.
Shock, Philadelphia: Lippincott Williams & Wilkins 2012, Vol. 37, (S1) : 56-56
Achouiti, A.; Vogl, T.; Urban, Constantin; et al.
PLoS Pathogens, San Fransisco: Public Library of Science 2012, Vol. 8, (10) : e1002987-
Achouiti, Ahmed; Vogl, Thomas; Urban, Constantin F; et al.
Frontiers in Immunology, Frontiers Media S.A 2012, Vol. 3
Hosseinzadeh, Ava; Messer, Philipp K; Urban, Constantin F
Mycoses, Vol. 55, (Supplement 4) : 24-24
Urban, Constantin F.; Reichenbach, J.; Bianchi, M.; et al.
Journal of Allergy and Clinical Immunology, Vol. 127, (5) : 1243-1252 e.7
Bianchi, Matteo; Niemiec, Maria J; Siler, Ulrich; et al.
Journal of Allergy and Clinical Immunology, St. Louis: C.V. Mosby 2011, Vol. 128, (3) : 687-688
Bianchi, Matteo; Niemiec, Maria J.; Siler, Ulrich; et al.
PLOS ONE, San Francisco: Public Library of Science 2011, Vol. 6, (12) : e28149-
Vethanayagam, R. Robert; Almyroudis, Nikolaos G.; Grimm, Melissa J.; et al.
Journal of innate immunity, Karger 2009, Vol. 1, (3) : 181-193
Ermert, David; Urban, Constantin F; Laube, Britta; et al.
Host-Pathogen Interactions: Methods and Protocols, Humana Press 2009 : 293-312
Ermert, David; Zychlinsky, Arturo; Urban, Constantin
PLoS Pathogens, Public Library of Science 2009, Vol. 5, (10)
Urban, Constantin F; Ermert, David; Schmid, Monika; et al.
Nature Medicine, Nature Publishing Group 2007, Vol. 13, (4) : 403-404
Urban, Constantin; Zychlinsky, Arturo
Current Drug Targets, Vol. 7, (4) : 505-512
Sohn, Kai; Schwenk, Jochen; Urban, Constantin; et al.
Cellular Microbiology, Blackwell Publishing 2006, Vol. 8, (11) : 1687-1696
Urban, Constantin F; Lourido, Sebastian; Zychlinsky, Arturo
Cellular Microbiology, Wiley-Blackwell 2006, Vol. 8, (4) : 668-676
Urban, Constantin F; Reichard, Ulrike; Brinkmann, Volker; et al.
Eukaryotic Cell, American Society for Microbiology 2005, Vol. 4, (12) : 2160-2169
Sohn, K; Roehm, M; Urban, Constantin; et al.

Research groups

Head of research
Constantin Urban Lab