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Staff photo Lars Thelander

Lars Thelander

Making the building blocks to the genome

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Affiliation
Affiliated as professor emeritus at Department of Medical Biochemistry and Biophysics
Location
KB. H6, Campus, Umeå Umeå universitet, 901 87 Umeå

The enzyme ribonucleotide reductase synthesize the building blocks to DNA. We want to understand how this synthesis is regulated in various organisms. We also study the nucleotide metabolism in Trypanosoms, a parasite that causes African sleeping sickness, with the goal to find new drug-targets.

2019
Journal of Biological Chemistry, American Society for Biochemistry and Molecular Biology 2019, Vol. 394, (44) : 15889-15897
Tran, Phong; Wanrooij, Paulina H.; Lorenzon, Paolo; et al.
2012
Journal of Biological Chemistry, Vol. 287, (21) : 17628-17636
Ranjbarian, Farahnaz; Vodnala, Munender; Vodnala, Sharvani Munender; et al.
2009
Biochemistry, Vol. 48, (27) : 6532-6539
Popović-Bijelić, Ana; Voevodskaya, Nina; Domkin, Vladimir; et al.
2008
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2008, Vol. 105, (46) : 17801-17806
Pontarin, Giovanna; Fijolek, Artur; Pizzo, Paola; et al.
2007
Journal of biological chemistry, Vol. 282, (16) : 11858-11865
Fijolek, Artur; Hofer, Anders; Thelander, Lars
2007
Journal of Biological Chemistry, Vol. 282, (23) : 16820-8
Pontarin, Giovanna; Ferraro, Paola; Håkansson, Pelle; et al.
2007
Nature. Genetics, Vol. 39, (6) : 703-4
Thelander, Lars
2006
Journal of Biological Chemistry, Vol. 281, (3) : 1778-1783
Håkansson, Pelle; Dahl, Lina; Chilkova, Olga; et al.
2006
Journal of Biological Chemistry, Vol. 281, (12) : 7834-7841
Håkansson, Pelle; Hofer, Anders; Thelander, Lars
2006
Journal of biological chemistry, Vol. 281, (36) : 26022-8
Narváez, Ana J; Voevodskaya, Nina; Thelander, Lars; et al.
2006
Proceedings of the National Academy of Sciences of the United States of America, Vol. 103, (26) : 9850-4
Voevodskaya, N; Narvaez, A-J; Domkin, Vladimir; et al.
2004
Journal of biological chemistry, Vol. 279, (11) : 10796-807
Chabes, Anna Lena; Björklund, Stefan; Thelander, Lars
2004
Journal of virology, Vol. 78, (8) : 4278-88
Lembo, David; Donalisio, Manuela; Hofer, Anders; et al.
2003
Cell, Vol. 112, (3) : 391-401
Chabes, Andrei; Georgieva, Bilyana; Domkin, Vladimir; et al.
2003
Cell Cycle, Vol. 2, (3) : 171-3
Chabes, Andrei; Thelander, Lars
2003
Proc. Natl. Acad. Sci. U S A., Vol. 100, (7) : 3925-3929
Chabes, Anna Lena; Pfleger, C.M.; Kirschner, M.W.; et al.
2003
European Journal of Biochemistry, Blackwell Publishing 2003, Vol. 270, (8) : 1791-1801
Kotova, Irina; Chabes, Anna Lena; Lobov, Sergei; et al.
2002
Journal of Biological Chemistry, Vol. 277, (21) : 18574-8
Domkin, Vladimir; Thelander, Lars; Chabes, Andrei
2002
Cell, Vol. 109, (5) : 563-73
Saitoh, Shigeaki; Chabes, Andrei; McDonald, W Hayes; et al.
2001
Journal of Biological Chemistry, Vol. 276, (44) : 40647-40651
Guittet, Olivier; Håkansson, Pelle; Voevodskaya, Nina; et al.
2001
Proceedings of the National Academy of Sciences of the U S A, Vol. 98, (11) : 6412-6
Hofer, Anders; Steverding, D; Chabes, Andrei; et al.
2001
European Journal of Biochemistry, Vol. 268, (16) : 4527-4536
Kotova, Irina; Chabes, Anna Lena; Segerman, Bo; et al.
2000
Proceedings of the National Academy of Sciences of the United States of America, Vol. 97, (6) : 2474-2479
Chabes, Andrei; Domkin, Vladimir; Larsson, Göran; et al.
2000
Journal of Virology, Vol. 74, (24) : 11557-65
Lembo, D; Gribaudo, G; Hofer, Anders; et al.
1999
Biochemistry, Vol. 38, (12) : 3610-4
Hayakawa, H; Hofer, Anders; Thelander, Lars; et al.
1998
Journal of Biological Chemistry, Vol. 273, (51) : 34098-104
Hofer, Anders; Ekanem, J T; Thelander, Lars
1998
Journal of Biological Chemistry, Vol. 273, (45) : 29816-21
Johansson, Erik; Hjortsberg, K; Thelander, Lars
1997
Proceedings of the National Academy of Sciences of the U S A, Vol. 94, (13) : 6959-64
Hofer, Anders; Schmidt, P P; Gräslund, Astrid; et al.
1996
Journal of Biological Chemistry, Vol. 271, (39) : 23698-704
Filatov, D; Björklund, Stefan; Johansson, Erik; et al.
1995
Journal of Biological Chemistry, Vol. 270, (50) : 30162-7
Johansson, Erik; Skogman, E; Thelander, Lars
1994
Advances in Experimental Medicine and Biology, Vol. 370 : 721-4
Johansson, Erik; Björklund, Stefan; Thelander, Lars
1993
Proceedings of the National Academy of Science U S A, Vol. 90, (23) : 11322-6
Björklund, Stefan; Hjortsberg, K; Johansson, Erik; et al.
1992
EMBO Journal, Vol. 11, (13) : 4953-4959
Björklund, Stefan; Skogman, E; Thelander, Lars
1990
Biochemistry, Vol. 29, (23) : 5452-5458
Björklund, Stefan; Skog, Sven; Tribukait, Bernard; et al.

Research groups

Head of research
Lars Thelander