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Syllabus:

Advanced Organic Chemistry, 15 Credits

The course is discontinued from 2021-08-09

Swedish name: Avancerad organisk kemi

This syllabus is valid: 2014-08-25 and until further notice

Course code: 5KE131

Credit points: 15

Education level: Second cycle

Main Field of Study and progress level: Chemistry: Second cycle, has only first-cycle course/s as entry requirements

Grading scale: TH teknisk betygsskala

Responsible department: Department of Chemistry

Revised by: Faculty Board of Science and Technology, 2021-08-09

Contents

The course builds on previous learning and provides in-depth knowledge in organic chemistry. The course is laboratory-oriented and the laboratory work aims to provide knowledge of advanced synthesis methodology, such as the handling of reactive intermediates in an inert atmosphere. The student shall, independently and with the help of the chemical literature, plan and practically conduct multi-step syntheses. Modern spectroscopic structure determination methods are used, in order to be able to evaluate the results of the syntheses.  Lectures complement the course literature within fields such as asymmetric synthesis, organometallic chemistry, retrosynthesis and spectroscopic methods.

Expected learning outcomes

After completing the course, student shall be able to:
*  independently plan and conduct advanced syntheses
*  use modern spectroscopic methods for structure determination
*  apply knowledge regarding organic reaction mechanisms in order to investigate the emergance of products and by-products
*  use organometallic coupling reactions to solve synthesis problems and
*  conduct basic retrosynthetic analyses.

Required Knowledge

Bioorganic Chemistry (5KE010/011, 15 credits), or equivalent knowledge. English A/5 or the equivalent.

Form of instruction

The teaching takes the form of lectures, lessons and laboratory experiments.
The course literature is obtained through self-tuition which is complemented with lectures within several fields, for example, asymmetric synthesis, organometallic chemistry, retrosynthesis and spectroscopic methods. The theoretical part of the course also includes a number of seminars where the multi-stage synthesis to polyfunctional target molecules is discussed. During the mandatory laboratory experiment period,  syntheses are conducted according to traditional methods where, for example, reactive reagents are handled in an inert atmosphere. In addition to this, modern methods that are yet to be described in textbooks are also used. For this reason, the syntheses are continuously replaced. A number of syntheses are also conducted in collaboration with research groups within and outside the University, which provides a link with modern research within organic chemistry. Following the laboratory experiment period, the students present their results at a mandatory seminar. The course concludes with a written exam.

Examination modes

The knowledge of the student is expressed partly in the form of verbal debriefings of the laboratory experiments, and partly through written tests at the end of the course.
Grades for the course are not allocated until both examinations and laboratory courses have been completed.
For the laboratory projects, the following grades are awarded: Fail (U), or Pass (G). For the written examination, and the whole course, the grades Fail (U), Pass (G) or Pass with distinction (VG) are awarded. To pass the whole course, all examinations and obligatory elements must have been passed. Students who fail their examination have the right to take it again.
A student who has taken two examinations for a course or a part of a course, without passing either examination, has the right to have another examiner appointed, if there are no specific reasons for not doing so (Chapter 6, Section 22, HEA). Requests for a different examiner are to be made to the Head of the Department of Chemistry.
Those who pass an examination may not take the same examination again with the aim of achieving a higher grade.
Credit transfers
Accreditation requests are always examined individually (see the University's Rules and Regulations and the Accreditation Regulations).

Literature

The literature list is not available through the web. Please contact the faculty.