Speakers
Professor Derk-Jan Dijk, PhD.
Professor of Sleep and Physiology, Director of the Surrey Sleep Research Centre, University of Surrey, UK.
Professor Anne Skeldon, PhD.
Professor of Mathematics, Head of School, School of Mathematics & Physics, University of Surrey, UK.
Sleep is among the most valued behaviours of humans and circadian rhythmicity is a fundamental characteristic of nearly all living systems. Insufficient sleep and disrupted circadian rhythmicity are risk factors for a wide range of negative health outcomes. Understanding the physiological mechanisms and environmental factors that regulate sleep and circadian rhythms will help to reduce the negative impact of aspects of industrialised societies, such as shiftwork and artificial light, on health. For a thorough and quantitative understanding of sleep-circadian regulation and the development of countermeasures, both human data and mathematical models are required.
Human Data: Derk-Jan Dijk will present an overview of the physiology of circadian rhythmicity and sleep regulation, the impact of environmental factors, molecular biomarkers for circadian rhythmicity and insufficient sleep and novel technologies for the longitudinal and contactless monitoring of sleep and circadian rhythms.
Mathematical Models: Anne Skeldon will give an overview of how translating laboratory results into mathematical equations helps us understand sleep in society, and with sometimes surprising results. She will show how combining data from wearable technologies with mathematical modelling suggests factors determining sleep phenotypes, and brings the opportunity for improved sleep and circadian health through a ‘digital-twin’ approach.
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