Research group STEM CELL AND BIOMATERIAL STRATEGIES FOR TISSUE REGENERATION
My research focuses on tissue regeneration using integrated in vitro, in vivo, and translational approaches, with a primary emphasis on oral and craniofacial tissues while also addressing broader regenerative applications. We aim to overcome key challenges such as limited vascularization, insufficient innervation, inflammation, and infection that restrict successful tissue repair.
By combining human stem cells with physiologically relevant tissue models and experimental regeneration systems, we recreate essential features of native tissue environments to study regenerative mechanisms and host–microbe interactions relevant to the oral microflora.
A central direction is the development of advanced tissue models and bioprinted systems to study regeneration of hard and mineralized tissues, together with stem cell–based approaches that improve cell survival, differentiation, and the performance of engineered tissue-like constructs. In parallel, we design biomaterial-based tissue-like constructs, with or without cells, to promote regeneration by enhancing angiogenesis and functional integration while modulating inflammation and controlling microbial challenges in the oral environment.
