Regenerative Endodontics and Oral Infection Biology
Research group
Our research focuses on developing biologically based therapies to preserve natural teeth and understanding how key pathogens and microbial communities influence health and disease. We investigate regenerative endodontics, host–microbe interactions, and the role of the oral and root canal microbiomes in oral infections and their potential impact on systemic health.
Regenerative endodontics – new approaches to tooth preservation
We develop and evaluate biologically based therapies for teeth with damaged or infected dental pulp. A particular focus is regenerative endodontics, which aims to stimulate the body's natural healing mechanisms and promote further root development in young patients. Through clinical studies, we investigate long-term treatment outcomes and explore new strategies, including probiotics, to improve treatment success.
Oral microbiome and host–microbe interactions
We investigate the root canal and oral microbiomes to understand how microorganisms contribute to infection, inflammation, and healing. Using microbiological and molecular approaches, we study microbial communities, their biological properties, and interactions with host tissues. Our goal is to identify factors associated with disease progression and treatment outcomes, providing a foundation for more targeted therapies.
Oral infections and systemic health
Another important area of our research explores the potential links between oral infections and systemic diseases, particularly cardiovascular diseases and infective endocarditis. We investigate how oral microorganisms may contribute to infections beyond the oral cavity and the potential role of endodontic infections. Through clinical and microbiological studies, we aim to improve our understanding of these associations and support better preventive strategies.