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Cryo-EM sample preparation and data collection course

The purpose of the course is to prepare and train cryoEM facility users in sample preparation methods, introduce users to the image data acquisition workflow, expand knowledge about cryo-EM methods among researchers and show that everyone can learn how to use cryo-EM for structural biology.

Course description 

The course is open for facility users or potential facility users, such as PhD students, postdocs, and researchers within the life sciences who are curious and will profit from cryo-EM skills. We welcome local and international applications. To attend, the course participants should be familiar with electron microscopy and structural biology. 

This course is supported by SciLifeLab, CryoNET and Umeå University and organized by the Umeå Centre for Electron Microscopy (UCEM). 

Course content

This course will cover practical aspects of cryo-EM sample preparation and data acquisition. 
 
The following topics will be covered: 

  • Overview of cryo-EM methods
  • Microscope design and electron optics 
  • Sample preparation 
  • Data collection for single particle analysis (SPA)
  • Introduction to SPA image processing 

The course consists of lectures, cryo lab work, demonstrations and practical exercises for all participants, hands-on experiences of microscopy operation and discussions. A detailed schedule will be provided to accepted participants. 

Course aim and literature

The aim of the course is for the participants to increase their knowledge about cryogenic electron microscopy methods, data collection and analysis, and acquire practical skills in sample preparation for cryo-EM. 

Course literature includes handouts and online resources.

Entry requirements 

Priority will be given to researchers involved in a project where the use of cryo-EM is needed, which are to be briefly described upon application. 
The course is suitable for researchers in the life sciences, with a masters or PhD degree, including graduate students, postdocs and staff scientists.   
A maximum of 18 participants will be admitted. Please provide a clear description of your research project and motivation for attending the course.  

Registration 

Application should be submitted before November 1st, 2026.

Registration form

Course:  Cryo-EM sample preparation and data collection course  

Dates:  1-3 December 2026

Place: Glasburen, KBC Building

(*) = this field is required

 

Lunch is not included in the course. However, coffee breaks will be provided throughout the course.

Please let us know about any dietary preferences or allergies we should be aware of.

Dietary requirements
Do you have any allergies ? *

** The information you submit here will be processed by Umeå University to administer and manage your registration. Read more about the processing of personal data at Umeå University (https://www.umu.se/processing-of-personal-data/).

Location 

Glasburen, KBC - Link to MAZEMAP
UCEM and Chemical Biological Centre (KBC) Building 
Umeå University 
Linnaeus väg 6 

Teachers and course instructors

  • Linda Sandblad
  • Ieva Ragaisyte
  • Lorene Gonnin
  • Tanvir Shaikh
  • Erin Schexnaydre
  • Additional teachers t.b.a 

Examination  

Participation in all parts of the course, lectures, lab, microscopy demonstrations and evaluation are mandatory. Upon completion, SciLifeLab and Umeå University will provide a course certificate and a recommendation for 1 ECTS. 

Contact

Ieva Ragaisyte

Staff Scientist

E-mail: ieva.ragaisyte@umu.se

Lorene Gonnin

Staff Scientist

E-mail: lorene.gonnin@umu.se

Latest update: 2026-09-10