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Annasara Lenman

Research qualifications: Docent

Contact

E-mail
Location
Virologi, Universitetssjukhuset by 6 Umeå universitet, 901 85 Umeå
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Works at

Affiliation
Staff scientist at Department of Clinical Microbiology Section: Section of Virology
Affiliation
Associate professor at Department of Clinical Microbiology Section: Section of Virology

Viruses that infect our respiratory tract are a leading cause of severe illness, mortality and place a heavy burden on healthcare. Unfortunately, we still lack medicines for many of these viruses.

   I am an associate professor in virology and head of a research group that investigates the various mechanisms that affect the severity of illness and recovery during viral infections. A better understanding of how viruses cause illness enables identification of targets for development of new treatments against respiratory viruses. We are also striving to identify mechanisms that are common for several different respiratory viruses so that a single treatment can be effective against many viruses.

   For our studies on respiratory viruses, we use a 3D-lung model composed of various cells typically found in the human lung. This model is based on cells that have been isolated from several different donors. By comparing how effectively the virus infects lung models from different donors, we attempt to identify host factors that explain why people have varying susceptibility to viral infections, with the goal of being able to tailor treatments for sensitive individuals.

mBio, American Society for Microbiology 2022, Vol. 13, (3)
Rosendal, Ebba; Mihai, Ionut Sebastian; Becker, Miriam; et al.
European Urology, Elsevier 2022, Vol. 81, (3) : 285-293
Welén, Karin; Rosendal, Ebba; Gisslén, Magnus; et al.
Viruses, MDPI 2021, Vol. 13, (6)
Arnberg, Niklas; Lenman, Annasara
Cells, MDPI 2021, Vol. 10, (7)
Kirui, Jared; Abidine, Yara; Lenman, Annasara; et al.
Viruses, MDPI 2021, Vol. 13, (10)
Persson, B. David; Nord, Stefan; Lindquist, Richard; et al.
Science Advances, American Association for the Advancement of Science 2021, Vol. 7, (2)
Rafie, Karim; Lenman, Annasara; Fuchs, J.; et al.
Viruses, MDPI 2021, Vol. 13, (2)
Rajan, Anandi; Palm, Elin; Trulsson, Fredrik; et al.
iScience, Elsevier 2021, Vol. 24, (12)
Zapatero-Belinchón, Francisco J.; Moeller, Rebecca; Lasswitz, Lisa; et al.
Journal of Neuroinflammation, BioMed Central (BMC) 2020, Vol. 17, (1)
Lindquist, Richard; Rosendal, Ebba; Weber, Elvira; et al.
Journal of Biological Chemistry, Elsevier 2020, Vol. 295, (50) : 16931-16948
Palor, Machaela; Stejskal, Lenka; Mandal, Piya; et al.
Journal of Virology, American Society for Microbiology 2020, Vol. 94, (14)
Persson, David; Lenman, Annasara; Frängsmyr, Lars; et al.
Proceedings of the National Academy of Sciences of the United States of America, Vol. 115, (18) : E4264-E4273
Lenman, Annasara; Liaci, A. Manuel; Liu, Yan; et al.
Umeå University medical dissertations, 1798
Lenman, Annasara
PLoS Pathogens, Vol. 11, (2)
Lenman, Annasara; Liaci, A. Manuel; Liu, Yan; et al.
Journal of Virology, Washington: The American Society For Microbiology 2011, Vol. 85, (24) : 13420-13431
Lenman, Annasara; Mueller, Steffen; Nygren, Mari I; et al.
Journal of Virology, Vol. 83, (8) : 3816-3825
Jonsson, Mari; Lenman, Annasara E; Frängsmyr, Lars; et al.
Lenman, Annasara; Liaci, A. Manuel; Frängsmyr, Lars; et al.

Research groups

Head of research
Annasara Lenman lab