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Umeå University
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Staff photo Carl-Johan Boraxbekk

Carl-Johan Boraxbekk

Professor of Cognitive Neuroscience of Aging

Research qualifications: Docent

Contact

E-mail
carl-johan.boraxbekk@umu.se
Phone
+46 90 786 62 12

Works as

Affiliation
Professor at Department of Diagnostics and Intervention
Location
5A, Målpunkt H62, Norrlands universitetssjukhus Umeå universitet, 901 85 Umeå
Affiliation
Affiliated as other position at Department of Medical and Translational Biology Section: Group Lars Nyberg
Location
hus H, Johan Bures väg 12, Biologihuset Umeå universitet, 901 87 Umeå

The vision I have for my research group is to identify and to optimize sustainable interventional strategies for improved or maintained brain health throughout the lifespan. The mission is to conduct interdisciplinary population-based cognitive neuroscience research that provides unique insights into the neuro-cognitive mechanisms of brain and cognitive aging, with a particular emphasis on novel interventions for neuro-enhancement.

Associations between inflammation and striatal dopamine D2-receptor availability in aging
Journal of Neuroinflammation, BioMed Central (BMC) 2025, Vol. 22, (1)
Crine, Vanessa; Papenberg, Goran; Johansson, Jarkko; et al.
Negotiating a physically active life in tune with ageing: a grounded theory study of older persons’ experiences of participating in high-intensity interval training
BMC Geriatrics, BioMed Central (BMC) 2025, Vol. 25, (1)
Fridberg, Helena; Wiklund, Maria; Snellman, Fredrik; et al.
Greater cognitive-motor interference among patients after anterior cruciate ligament reconstruction compared with controls
American Journal of Sports Medicine, Sage Publications 2025, Vol. 53, (5) : 1041-1049
Strong, Andrew; Boraxbekk, Carl-Johan; Markström, Jonas L.
"Recovery activities are needed every step of the way": exploring the process of long-term recovery in people previously diagnosed with exhaustion disorder
BMC Psychology, BioMed Central (BMC) 2024, Vol. 12, (1)
Aronsson, Ingela; Neely, Anna Stigsdotter; Boraxbekk, Carl-Johan; et al.
Effects of controlled supramaximal high-intensity interval training on muscle capacities and physical functions for older adults: analysis of secondary outcomes from the Umeå HIT study-a randomised controlled trial
Age and Ageing, Oxford University Press 2024, Vol. 53, (10)
Frykholm, Erik; Hedlund, Mattias; Becker, Clemens; et al.
Applicability of a supramaximal high-intensity interval training program for older adults previously not engaged in regular exercise: analyses of secondary outcomes from the Umeå HIT Study
Psychology of Sport And Exercise, Elsevier 2024, Vol. 73
Frykholm, Erik; Simonsson, Emma; Levik Sandström, Sofi; et al.
Effects and mechanisms of supramaximal high-intensity interval training on extrapulmonary manifestations in people with and without chronic obstructive pulmonary disease (COPD-HIIT): study protocol for a multi-centre, randomized controlled trial
Trials, BioMed Central (BMC) 2024, Vol. 25, (1)
Jakobsson, Johan; Burtin, Chris; Hedlund, Mattias; et al.
Brain change trajectories in healthy adults correlate with Alzheimer’s related genetic variation and memory decline across life
Nature Communications, Nature Publishing Group 2024, Vol. 15, (1)
Roe, James M.; Vidal-Piñeiro, Didac; Sørensen, Øystein; et al.
Lifestyle-related risk factors and their cumulative associations with hippocampal and total grey matter volume across the adult lifespan: a pooled analysis in the European Lifebrain consortium
Brain Research Bulletin, Elsevier 2023, Vol. 200
Binnewies, Julia; Nawijn, Laura; Brandmaier, Andreas M.; et al.
Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults
Human Brain Mapping, John Wiley & Sons 2023, Vol. 44, (11) : 4299-4309
Demnitz, Naiara; Gates, Anne T.; Mortensen, Erik L.; et al.
Characterising the covariance pattern between lifestyle factors and structural brain measures: a multivariable replication study of two independent ageing cohorts
Neurobiology of Aging, Elsevier 2023, Vol. 131 : 115-123
Demnitz, Naiara; Hulme, Oliver J.; Siebner, Hartwig R.; et al.
White matter lesion load determines exercise-induced dopaminergic plasticity and working memory gains in aging
Translational Psychiatry, Springer Nature 2023, Vol. 13, (1)
Farnsworth von Cederwald, Bryn; Johansson, Jarkko; Riklund, Katrine; et al.
No phenotypic or genotypic evidence for a link between sleep duration and brain atrophy
Nature Human Behaviour, Springer Nature 2023, Vol. 7, (11) : 2008-2022
Fjell, Anders M.; Sørensen, Øystein; Wang, Yunpeng; et al.
Is short sleep bad for the brain?: Brain structure and cognitive function in short sleepers
Journal of Neuroscience, Vol. 43, (28) : 5241-5250
Fjell, Anders M.; Sørensen, Øystein; Wang, Yunpeng; et al.
No moderating influence of education on the association between changes in hippocampus volume and memory performance in aging
Aging Brain, Elsevier 2023, Vol. 4
Lövdén, Martin; Pagin, Amos; Bartrés-Faz, David; et al.
Subjective cognitive complaints and its associations to response inhibition and neural activation in patients with stress-related exhaustion disorder
Stress, Taylor & Francis 2023, Vol. 26, (1)
Nelson, Andreas; Malmberg Gavelin, Hanna; Andersson, Micael; et al.
Individual differences in brain aging: heterogeneity in cortico-hippocampal but not caudate atrophy rates
Cerebral Cortex, Oxford University Press 2023, Vol. 33, (9) : 5075-5081
Nyberg, Lars; Andersson, Micael; Lundquist, Anders; et al.
Effects of acute physical activity on brain metabolites as measured by magnetic resonance spectroscopy (1H-MRS) in humans: a systematic review
Heliyon, Elsevier 2023, Vol. 9, (10)
Ryberg, Mathias; Boraxbekk, Carl-Johan; Kjaer, Michael; et al.
Age-independent transfer after successful associative mnemonic training
Journal of Cognitive Enhancement, Springer Nature 2023, Vol. 7, (3-4) : 159-172
Sandberg, Petra; Boraxbekk, Carl-Johan; Zogaj, Idriz; et al.
Effects of controlled supramaximal high-intensity interval training on cardiorespiratory fitness and global cognitive function in older adults: the Umeå hit study-a randomized controlled trial
The journals of gerontology. Series A, Biological sciences and medical sciences, Oxford University Press 2023, Vol. 78, (9) : 1581-1590
Simonsson, Emma; Levik Sandström, Sofi; Hedlund, Mattias; et al.
Emotion-induced brain activation across the menstrual cycle in individuals with premenstrual dysphoric disorder and associations to serum levels of progesterone-derived neurosteroids
Translational Psychiatry, Springer Nature 2023, Vol. 13, (1)
Stiernman, Louise; Dubol, Manon; Comasco, Erika; et al.
Right hemisphere brain lateralization for knee proprioception among right-limb dominant individuals
Frontiers in Human Neuroscience, Frontiers Media S.A. 2023, Vol. 17
Strong, Andrew; Grip, Helena; Arumugam, Ashokan; et al.
The effect of two multi-component behavior change interventions on cognitive functions
BMC Public Health, BioMed Central (BMC) 2022, Vol. 22, (1)
Bojsen-Møller, Emil; Wang, Rui; Nilsson, Jonna; et al.
Dopamine d2/3-receptor availability and its association with autonomous motivation to exercise in older adults: an exploratory [11c]-raclopride study
Frontiers in Human Neuroscience, Frontiers Media S.A. 2022, Vol. 16
Simonsson, Emma; Jonasson Stiernman, Lars; Lundquist, Anders; et al.
Brain Response to a Knee Proprioception Task Among Persons With Anterior Cruciate Ligament Reconstruction and Controls
Frontiers in Human Neuroscience, Frontiers Media S.A. 2022, Vol. 16
Strong, Andrew; Grip, Helena; Boraxbekk, Carl-Johan; et al.
Brain aging differs with cognitive ability regardless of education
Scientific Reports, Nature Publishing Group 2022, Vol. 12, (1)
Walhovd, Kristine B.; Nyberg, Lars; Lindenberger, Ulman; et al.
Effekter av konditionsträning periodiserad utifrån menstruationscykeln hos idrottande kvinnor
FOU rapport, 2022:5
Wikström-Frisén, Lisbeth; Boraxbekk, Carl-Johan; Larsén, Karin
Right-left asymmetry in corticospinal tract microstructure and dexterity are uncoupled in late adulthood
NeuroImage, Elsevier 2021, Vol. 240
Demnitz, Naiara; Madsen, Kathrine Skak; Johnsen, Line K.; et al.
Multimodal Image Analysis of Apparent Brain Age Identifies Physical Fitness as Predictor of Brain Maintenance
Cerebral Cortex, Oxford University Press 2021, Vol. 31, (7) : 3393-3407
Dunås, Tora; Wåhlin, Anders; Nyberg, Lars; et al.
Individual finger movement control and association to brain activity in healthy participants
XXVIII Congress of the International Society Biomechanics (ISB), Digital, July 25-29, 2021
Grip, Helena; Johansson, Anna-Maria; Rönnqvist, Louise; et al.
Influence of visual feedback, hand dominance and sex on individuated finger movements
Experimental Brain Research, Springer 2021, Vol. 239, (6) : 1911-1928
Johansson, Anna-Maria; Grip, Helena; Rönnqvist, Louise; et al.
Do glia provide the link between low-grade systemic inflammation and normal cognitive ageing?: A 1H magnetic resonance spectroscopy study at 7 tesla
Journal of Neurochemistry, Wiley-Blackwell 2021, Vol. 159, (1) : 185-196
Lind, Anna; Boraxbekk, Carl-Johan; Petersen, Esben Thade; et al.
Subjective cognitive complaints in patients with stress-related exhaustion disorder: a cross sectional study
BMC Psychology, BioMed Central 2021, Vol. 9, (1)
Nelson, Andreas; Malmberg Gavelin, Hanna; Boraxbekk, Carl-Johan; et al.
Educational attainment does not influence brain aging
Proceedings of the National Academy of Sciences of the United States of America, Vol. 118, (18)
Nyberg, Lars; Magnussen, Fredrik; Lundquist, Anders; et al.
Ancient Mnemonic in New Format: Episodic Memory Training With the Method of Loci in a Smart Phone Application
The journals of gerontology. Series B, Psychological sciences and social sciences, Oxford University Press 2021, Vol. 76, (4) : 681-691
Sandberg, Petra; Boraxbekk, Carl-Johan; Zogaj, Idriz; et al.
The Effects of Working Memory Updating Training in Parkinson's Disease: A Feasibility and Single-Subject Study on Cognition, Movement and Functional Brain Response
Frontiers in Psychology, Frontiers Media S.A. 2021, Vol. 11
Walton, Lois; Eriksson Domellöf, Magdalena; Boraxbekk, Carl-Johan; et al.
Walking Time Is associated With Hippocampal Volume in Overweight and Obese Office Workers
Frontiers in Human Neuroscience, Frontiers Media S.A. 2020, Vol. 14
Bergman, Frida; Matsson-Frost, Tove; Jonasson, Lars S.; et al.
Evaluating a frontostriatal working-memory updating-training paradigm in Parkinson's disease: the iPARK trial, a double-blinded randomized controlled trial
BMC Neurology, Springer Nature 2020, Vol. 20, (1)
Domellöf, Magdalena Eriksson; Walton, Lois; Boraxbekk, Carl-Johan; et al.
Hopeful struggling for health: Experiences of participating in computerized cognitive training and aerobic training for persons with stress-related exhaustion disorder
Scandinavian Journal of Psychology, John Wiley & Sons 2020, Vol. 61, (3) : 361-368
Eskilsson, Therese; Fjellman-Wiklund, Anncristine; Ek Malmer, Elin; et al.
The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults
Experimental Gerontology, Elsevier 2020, Vol. 136
Gylling, Anne Theil; Eriksen, Christian Skou; Garde, Ellen; et al.
Stimulating aged brain with transcranial direct current stimulation: Opportunities and challenges
Psychiatry Research: Neuroimaging, Elsevier 2020, Vol. 306
Habich, Annegret; Fehér, Kristoffer D.; Antonenko, Daria; et al.
High long-term test-retest reliability for extrastriatal 11C-raclopride binding in healthy older adults
Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2020, Vol. 40, (9) : 1859-1868
Karalija, Nina; Jonasson, Lars S.; Johansson, Jarkko; et al.
Regional myo-inositol, creatine and choline levels are higher at older age and scale negatively with visuo-spatial working memory: a cross-sectional proton MR spectroscopy study at 7 tesla on normal ageing
Journal of Neuroscience, The Society for Neuroscience 2020, Vol. 40, (42) : 8149-8159
Lind, Anna; Boraxbekk, Carl-Johan; Petersen, Esben Thade; et al.
Mental fatigue in stress-related exhaustion disorder: structural brain correlates, clinical characteristics and relations with cognitive functioning
NeuroImage: Clinical, Elsevier 2020, Vol. 27
Malmberg Gavelin, Hanna; Stigsdotter Neely, Anna; Dunås, Tora; et al.
Biological and environmental predictors of heterogeneity in neurocognitive ageing: Evidence from Betula and other longitudinal studies
Ageing Research Reviews, Elsevier 2020, Vol. 64
Nyberg, Lars; Boraxbekk, Carl-Johan; Eriksson Sörman, Daniel; et al.
Maintenance of muscle strenght following a one-year resistance training program in older adults
Experimental Gerontology, Elsevier 2020, Vol. 139
Thiel Gylling, Anne; Bloch-Ibenfeldt, Mads; Skou Eriksen, Christian; et al.
Distinct effects of acute exercise and breaks in sitting on working memory and executive function in older adults: a three-arm, randomised cross-over trial to evaluate the effects of exercise with and without breaks in sitting on cognition
British Journal of Sports Medicine, BMJ Publishing Group Ltd 2020, Vol. 54, (13) : 776-781
Wheeler, Michael; Green, Daniel; Ellis, Kathryn; et al.
Copenhagen Consensus statement 2019: physical activity and ageing
British Journal of Sports Medicine, London: BMJ Publishing Group Ltd 2019, Vol. 53, (14) : 856-858
Bangsbo, Jens; Blackwell, Joanna; Boraxbekk, Carl-Johan; et al.
Relationships between Physical Activity, Sedentary Behaviour and Cognitive Functions in Office Workers
International Journal of Environmental Research and Public Health, MDPI 2019, Vol. 16, (23)
Bojsen-Moller, Emil; Boraxbekk, Carl-Johan; Ekblom, Orjan; et al.
Development and Feasibility of a Regulated, Supramaximal High-Intensity Training Program Adapted for Older Individuals
Frontiers in Physiology, Frontiers Media S.A. 2019, Vol. 10
Hedlund, Mattias; Lindelöf, Nina; Johansson, Bengt; et al.
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