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Staff photo Denise Rawcliffe

Denise Rawcliffe

My research project is centered around the protein POF (Painting of Fourth). POF specifically binds to the fourth chromosome of the fruitfly (Drosophila melanogaster).  

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Postdoctoral fellow at Department of Molecular Biology Units: Research group Jan Larsson, Postdocs Dept of Molecular Biology
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The fruit fly (Drosophila melanogaster) is an organism that is well-known for its use as a model for genetics studies. D. melanogaster has four autosomal chromosomes but also an X and a Y chromosome. Among the autosomal chromosomes, the fourth chromosome is the smallest. This chromosome contains very few genes and consists mostly of heterochromatin.  My research project is centered around the protein POF (Painting of Fourth). POF specifically binds to the fourth chromosome. The aim of the project is to identify proteins that interact with POF. By identifying binding partners of POF we can understand more of the mechanism behind the specific binding of POF to the fourth chromosome.

2018
Umeå University medical dissertations, 1978
Rawcliffe, Denise F. R.
2018
Molecular Genetics & Genomic Medicine, John Wiley & Sons 2018, Vol. 6, (6) : 887-897
Rawcliffe, Denise F. R.; Österman, Lennart; Nordin, Angelica; et al.
2016
PLoS ONE, Public library science 2016, Vol. 11, (10)
Rawcliffe, Denise F. R.; Österman, Lennart; Lindsten, Hans; et al.

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