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Staff photo Ji-Guo Yu

Ji-Guo Yu

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Affiliation
Associate professor at Department of Community Medicine and Rehabilitation Units: Sports Medicine
Location
Biologihuset hus B, plan 6, Umeå universitet, Avdelningen för Idrottsmedicin Umeå universitet, 901 87 Umeå

Research


Project name: Muscular and nerve signal substance adaptations in the triceps surae muscle of rabbit – Evaluations of a model leading to muscle overuse

Summary of the project: The effects of muscle overuse are not fully known. Muscle overuse is related to pain signaling and to some extent inflammatory reactions. One approach applied in the project is the use of surface electrical stimulation (SES) on rabbit skeletal muscle. SES on human skeletal muscle has been used both for healthy active populations as a supplement to conventional conditioning training and for rehabilitation of persons with muscle functional loss. Evidence has shown that electrical stimulation is especially effective in increasing muscle strength when the SES is combined with simultaneous voluntary activity. However, long term of SES on muscular and nerve signal substance adaptation has hardly been approached.

A rabbit model with a specially constructed apparatus (a kicking machine) was used for the study of muscle overuse. Rabbit triceps surae muscle was applied with SES for 2 hour every other day for 1, 3 and 6 weeks. Muscle biopsy was taken after the last session of SES and analyzed for muscular and neuropeptides alterations.

The overall aims of this project were:

  • To evaluate the morphological changes, with particular emphasis on the muscle fiber type patterns and the blood vessel.
  • To study the distribution patterns of the neuropeptide SP and the NK-1 receptor in the experimental situation in comparison with that of the controls.
  • To compare the situation concerning aspects (1) and (2) in the two muscles comprising the triceps surae: the soleus and gastrocnemius muscles.
  • To evaluate the effects on the experimental leg in comparison with the contralateral control leg (the contralateral triceps surae muscle).

Research founding: CIF, Chinese government scholarship and Umeå University medical faculty

Collaborators: Yafeng Song, Per Stål, Sture Forsgren (IMB, Section for anatomy)
Ronny Lorentzon (IME)

Frontiers in Physiology, FRONTIERS MEDIA SA 2020, Vol. 11
Lv, Yuanyuan; Zhao, Wenying; Yu, Laikang; et al.
Journal of Sports Medicine and Physical Fitness, Edizioni Minerva Medica 2020, Vol. 60, (7) : 1040-1048
Yu, Ji-Guo; Isaksson, Andreas; Rova, Anton; et al.
Journal of Sports Medicine and Physical Fitness, Edizioni Minerva Medica 2018, Vol. 58, (9) : 1185-1189
Bengtsson, Victor; Yu, Ji-Guo; Gilenstam, Kajsa
European Journal of Sport Science, Vol. 17, (2) : 249-256
Brännström, André; Yu, Ji-Guo; Jonsson, Per; et al.
International Journal of Exercise Science, Vol. 8, (3) : 287-296
Hallenstål, Tove; Sundqvist, Ida; Svensson, Michael; et al.
PLoS ONE, Vol. 9, (12) : e116455-
Song, Yafeng; Forsgren, Sture; Liu, Jing-Xia; et al.
PLoS ONE, Public Library Science 2014, Vol. 9, (9)
Yu, Ji-Guo; Bonnerud, Patrik; Eriksson, Anders; et al.
American Journal of Sports Science, Vol. 1, (2) : 12-17
Alm, Petter; Yu, Ji-Guo
Sport and Art, Vol. 1, (1) : 18-23
Brännström, André; Rova, Anton; Yu, Jiguo
Sport and Art, Vol. 1, (2) : 34-40
Sandgren, Evelina; Karlsson, Mia; Yu, Ji-Guo
BMC Musculoskeletal Disorders, BioMed Central 2013, Vol. 14
Song, Yafeng; Stål, Per; Yu, Jiguo; et al.
PLoS ONE, Vol. 8, (4)
Yu, Ji-Guo; Liu, Jing-Xia; Carlsson, Lena; et al.
Histochemistry and Cell Biology, Heidelberg: Springer Berlin/Heidelberg 2012, Vol. 138, (1) : 89-99
Malm, Christer; Yu, Ji-Guo
PLoS ONE, Public Library Science 2012, Vol. 7, (12) : e52230-
Song, Yafeng; Forsgren, Sture; Yu, Jiguo; et al.
Journal of Atherosclerosis and Thrombosis, Vol. 16, (1) : 21-29
Yu, Ji-Guo; Sewright, Kimberly; Hubal, Monica; et al.
Histochemistry and Cell Biology, Vol. 130, (1) : 91-103
Carlsson, Lena; Yu, Ji-Guo; Thornell, Lars-Eric
Neuromuscular Disorders, Elsevier 2007, Vol. 17, (1) : 61-68
Carlsson, Lena; Yu, Ji-Guo; Moza, Monica; et al.
J Histochem Cytochem, Vol. 53, (7) : 839-44
Yu, Ji-Guo; Russell, Brenda
Histochemistry and Cell Biology, Vol. 121, (3) : 219-227
Yu, Ji-Guo; Carlsson, Lena; Thornell, Lars-Eric
Histochemistry and Cell Biology, Springer-Verlag New York 2003, Vol. 119, (5) : 383-93
Yu, Ji-Guo; Fürst, Dieter O; Thornell, Lars-Eric
Histochemistry and Cell Biology, Springer 2002, Vol. 118, (1) : 29-34
Yu, Ji-Guo; Malm, Christer; Thornell, Lars-Eric
Histochemistry and Cell Biology, Springer 2002, Vol. 118, (2) : 171-9
Yu, Ji-Guo; Thornell, Lars-Eric
Chinese journal of sports medicine, Vol. 17, (02) : 158-161
Jianwei, Ju; Shizhang, Zhou; Tiquan, Zhu; et al.
Chinese Journal of Sports Medicine, Vol. 16, (2) : 145-147
Yu, Ji-Guo; Che, Baoren
Yantai Teachers University Journal, Vol. 12, (2) : 138-141
Yu, Ji-Guo; Che, Baoren
Journal of Physical Education, Vol. 4, (2) : 20-22
Yu, Ji-Guo; Che, Baoren
Shandong Sports Science & Technology, Vol. 15, (3) : 45-47
Yu, JiGuo; Che, Baoren
Journal of Shanghai Physical Education Institute, Vol. 19, (S1) : 102-104
Baoren, Che; Ji-Guo, Yu
Shandong Sports Science & Technology, Vol. 18, (1) : 5-8
Yu, JiGuo; Che, Baoren
Journal of Shandong Physical Education Institute, Vol. 11, (1) : 31-35
Yu, Ji-Guo; Sun, Gaofeng; Zhang, Benqiang
Sport Science, Vol. 14, (6) : 67-72
Yu, Ji-Guo; Xu, Haowen
YANTAI TEACHERS COLLEGE JOURNAL, Vol. 10, (2) : 129-133
Yu, Ji-Guo; Zhu, Tiquan; Zhou, Shizhang
Yantai Teachers University Journal, Vol. 9, (1) : 56-59
Yu, Ji-Guo