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Jonas Barandun

As a structural biologist, I am fascinated by how evolution has shaped important molecular mechanisms and how pathogens use these for infection. I am a SciLifeLab National Fellow.


Works at

Affiliated as research fellow at Molecular Infection Medicine Sweden (MIMS) Section: Research groups
6L, Institutionen för molekylärbiologi Institutionen för molekylärbiologi, 90187 Umeå
Affiliated as other position at Department of Molecular Biology Section: Group Jonas Barandun
6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

In my research group, we are using a combination of in vivo assays, biochemistry and cryo-electron microscopy to study macromolecular complexes of specialized pathogenic organisms. We would like to understand the molecular basis of essential pathways in pathogens and uncover unique structural determinants that could serve as novel targets for antibiotics.


Scientific publications

Read more about my reserach:

The Barandun lab

Barandun lab, MIMS

Barandun lab, Integrated Structural Biology (ISB)



Molecular biology and evolution, Oxford University Press 2024, Vol. 41, (1)
Schierholz, Léon; Brown, Charlotte R.; Helena-Bueno, Karla; et al.
PLoS biology, Public Library of Science (PLoS) 2024, Vol. 22, (2)
Sharma, Himanshu; Jespersen, Nathan; Ehrenbolger, Kai; et al.
BMC Genomics, BioMed Central (BMC) 2024, Vol. 25, (1)
Svedberg, Dennis; Winiger, Rahel R.; Berg, Alexandra; et al.
Nature Chemical Biology, Nature Publishing Group 2023, Vol. 19 : 440-450
Meier, Gianmarco; Thavarasah, Sujani; Ehrenbolger, Kai; et al.
Nature Communications, Nature Publishing Group 2022, Vol. 13, (1)
Jespersen, Nathan; Ehrenbolger, Kai; Winiger, Rahel; et al.
Microsporidia: current advances in biology, Cham: Springer 2022 : 1-42
Jespersen, Nathan; Monrroy, Leonardo; Barandun, Jonas
eLIFE, eLife Sciences Publications, Ltd 2022, Vol. 11
Nadeem, Aftab; Berg, Alexandra; Pace, Hudson; et al.
PLoS biology, Public Library of Science 2020, Vol. 18, (10)
Ehrenbolger, Kai; Jespersen, Nathan; Sharma, Himanshu; et al.
Nature Microbiology, Nature Publishing Group 2019, Vol. 4, (11) : 1798-1804
Barandun, Jonas; Hunziker, Mirjam; Vossbrinck, Charles R.; et al.

Research groups

Head of research
Jonas Barandun Lab