Laura Alvarez

Contact

laura.alvarez@umu.se

+46 90 785 25 25

Works at

Staff scientist at Department of Molecular Biology Section: Research group Felipe Cava

6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå

A distinctive family of L,D-transpeptidases catalyzing L-Ala-mDAP crosslinks in Alpha- and Betaproteobacteria

Nature Communications, Springer Nature 2024, Vol. 15, (1)

Espaillat, Akbar; Alvarez, Laura; Torrens, Gabriel; et al.

EstG is a novel esterase required for cell envelope integrity in Caulobacter

Current Biology, Cell Press 2023, Vol. 33, (2) : 228-240.e7

Daitch, Allison K.; Orsburn, Benjamin C.; Chen, Zan; et al.

D-amino acids signal a stress-dependent run-away response in Vibrio cholerae

Nature Microbiology, Springer Nature 2023, Vol. 8, (8) : 1549-1560

Irazoki, Oihane; ter Beek, Josy; Alvarez, Laura; et al.

Hydroxyl Radical Overproduction in the Envelope: An Achilles' Heel in Peptidoglycan Synthesis

Microbiology Spectrum, American Society for Microbiology 2022, Vol. 10, (1)

Giacomucci, Sean; Alvarez, Laura; Rodrigues, Christopher D.A.; et al.

Lytic transglycosylases mitigate periplasmic crowding by degrading soluble cell wall turnover products

eLIFE, eLife Sciences Publications Ltd 2022, Vol. 11

Weaver, Anna; Alvarez, Laura; Rosch, Kelly; et al.

Cell Wall Biology of Vibrio cholerae

Annual Review of Microbiology, ANNUAL REVIEWS 2021, Vol. 75 : 151-174

Alvarez, Laura; Hernandez, Sara B.; Cava, Felipe

BipA exerts temperature-dependent translational control of biofilm-associated colony morphology in Vibrio cholerae

eLIFE, eLife Sciences Publications Ltd. 2021, Vol. 10

del Peso Santos, Teresa; Alvarez, Laura; Sit, Brandon; et al.

Class a penicillin-binding protein-mediated cell wall synthesis promotes structural integrity during peptidoglycan endopeptidase insufficiency in vibrio cholerae

mBio, American Society for Microbiology 2021, Vol. 12, (2)

Murphy, Shannon G.; Murtha, Andrew N.; Zhao, Ziyi; et al.

Pbp4 is likely involved in cell division of the longitudinally dividing bacterium candidatus thiosymbion oneisti

Antibiotics, MDPI 2021, Vol. 10, (3) : 1-17

Wang, Jinglan; Alvarez, Laura; Bulgheresi, Silvia; et al.

Analysis of Gram-negative Bacteria Peptidoglycan by Ultra-performance Liquid Chromatography

Bio-protocol, Bio-protocol 2020, Vol. 10, (19)

Alvarez, Laura; Cordier, Baptiste; van Teeffelen, Sven; et al.

Impaired Alanine Transport or Exposure to D-Cycloserine Increases the Susceptibility of MRSA to beta-lactam Antibiotics

Journal of Infectious Diseases, OXFORD UNIV PRESS INC 2020, Vol. 221, (6) : 1006-1016

Gallagher, Laura A.; Shears, Rebecca K.; Fingleton, Claire; et al.

Structural basis of peptidoglycan endopeptidase regulation

Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2020, Vol. 117, (21) : 11692-11702

Shin, Jung-Ho; Sulpizio, Alan G.; Kelley, Aaron; et al.

Class-A penicillin binding proteins do not contribute to cell shape but repair cell-wall defects

eLIFE, eLife Sciences Publications 2020, Vol. 9

Vigouroux, Antoine; Cordier, Baptiste; Aristov, Andrey; et al.

The conserved transcriptional regulator CdnL is required for metabolic homeostasis and morphogenesis in Caulobacter

PLOS Genetics, Public Library of Science (PLOS) 2020, Vol. 16, (1)

Woldemeskel, Selamawit Abi; Daitch, Allison K.; Alvarez, Laura; et al.

A new family of nitrate/nitrite transporters involved in denitrification

International Microbiology, Springer-Verlag New York 2019, Vol. 22, (1) : 19-28

Alvarez, Laura; Sanchez-Hevia, Dione; Sanchez, Mercedes; et al.

Fluorogenic D-amino acids enable real-time monitoring of peptidoglycan biosynthesis and high-throughput transpeptidation assays

Nature Chemistry, Nature Publishing Group 2019, Vol. 11, (4) : 335-341

Hsu, Yen-Pang; Hall, Edward; Booher, Garrett; et al.

Mechanisms of Incorporation for D-Amino Acid Probes That Target Peptidoglycan Biosynthesis

ACS Chemical Biology, American Chemical Society (ACS) 2019, Vol. 14, (12) : 2745-2756

Kuru, Erkin; Radkov, Atanas; Meng, Xin; et al.

Endopeptidase Regulation as a Novel Function of the Zur-Dependent Zinc Starvation Response

mBio, American Society for Microbiology 2019, Vol. 10, (1)

Murphy, Shannon G.; Alvarez, Laura; Adams, Myfanwy C.; et al.

New Insights Into the Mechanisms and Biological Roles of D-Amino Acids in Complex Eco-Systems

Frontiers in Microbiology, Frontiers Media S.A. 2018, Vol. 9

Aliashkevich, Alena; Alvarez, Laura; Cava, Felipe

Bacterial secretion of D-arginine controls environmental microbial biodiversity

The ISME Journal, Nature Publishing Group 2018, Vol. 12, (2) : 438-450

Alvarez, Laura; Aliashkevich, Alena; de Pedro, Miguel A.; et al.

Bacterial Competition Assay Based on Extracellular D-amino Acid Production

Bio-protocol, BIO-PROTOCOL 2018, Vol. 8, (7)

Alvarez, Laura; Cava, Felipe

The role of conserved proteins DrpA and DrpB in nitrate respiration of Thermus thermophilus

Environmental Microbiology, John Wiley & Sons 2018, Vol. 20, (10) : 3851-3861

Chahlafi, Zahra; Alvarez, Laura; Cava, Felipe; et al.

The chaperone activities of dsbg and spy restore peptidoglycan biosynthesis in the elyC mutant by preventing envelope protein aggregation

Journal of Bacteriology, American Society for Microbiology 2018, Vol. 200, (19)

Kouidmi, Imène; Alvarez, Laura; Collet, Jean François; et al.

Hierarchical control of nitrite respiration by transcription factors encoded within mobile gene clusters of Thermus thermophilus

Genes, MDPI 2017, Vol. 8, (12)

Alvarez, Laura; Quintáns, Nieves G.; Blesa, Alba; et al.

rstB Regulates Expression of the Photobacterium damselae subsp damselae Major Virulence Factors Damselysin, Phobalysin P and Phobalysin C

Frontiers in Microbiology, FRONTIERS MEDIA SA 2017, Vol. 8

Terceti, Mateus S.; Rivas, Amable J.; Alvarez, Laura; et al.

Ultra-sensitive, high-resolution liquid chromatography methods for the high-throughput quantitative analysis of bacterial cell wall chemistry and structure

Bacterial cell wall homeostasis: methods and protocols /edited by Hee-Jeon Hong, New York: Humana Press 2016 : 11-27

Alvarez, Laura; Hernandez, Sara B; de Pedro, Miguel A; et al.

A cell wall damage response mediated by a sensor kinase/response regulator pair enables beta-lactam tolerance

Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, (2) : 404-409

Dörr, Tobias; Alvarez, Laura; Delgado, Fernanda; et al.

A D, D-carboxypeptidase is required for Vibrio cholerae halotolerance

Environmental Microbiology, Wiley-Blackwell 2015, Vol. 17, (2) : 527-540

Möll, Andrea; Dörr, Tobias; Alvarez, Laura; et al.

Peptidoglycan Remodeling by the Coordinated Action of Multispecific Enzymes

Microbial Drug Resistance, Vol. 20, (3) : 190-198

Alvarez, Laura; Espaillat, Akbar; Hermoso, Juan A.; et al.

A novel peptidoglycan binding protein crucial for PBP1A-mediated cell wall biogenesis in Vibrio cholerae

PLOS Genetics, Public library science 2014, Vol. 10, (6) : e1004433-

Dörr, Tobias; Lam, Hubert; Alvarez, Laura; et al.

Structural basis for the broad specificity of a new family of amino-acid racemases

Acta Crystallographica Section D: Biological Crystallography, Wiley-Blackwell 2014, Vol. 70 : 79-90

Espaillat, Akbar; Carrasco-Lopez, Cesar; Bernardo-Garcia, Noelia; et al.

Cell Separation in Vibrio cholerae Is Mediated by a Single Amidase Whose Action Is Modulated by Two Nonredundant Activators

Journal of Bacteriology, American Society for Microbiology 2014, Vol. 196, (22) : 3937-3948

Moell, Andrea; Doerr, Tobias; Alvarez, Laura; et al.

View publications in DiVA

Research groups

Group member

Felipe Cava lab

Published: 19 Feb, 2024

Discovery about bacterial cell walls can lead to new antibiotics