Vimal Parkash

Contact

Works as

Staff scientist at Department of Medical Biochemistry and Biophysics Section: Erik Johansson group

KB. A5, Campus, Umeå Umeå universitet, 901 87 Umeå

The POLγ Y951N patient mutation disrupts the switch between DNA synthesis and proofreading, triggering mitochondrial DNA instability

Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences (PNAS) 2025, Vol. 122, (16)

Forslund, Josefin M.E.; Nguyen, Tran V. H.; Parkash, Vimal; et al.

A sensor complements the steric gate when DNA polymerase ϵ discriminates ribonucleotides

Nucleic Acids Research, Oxford University Press 2023, Vol. 51, (20) : 11225-11238

Parkash, Vimal; Kulkarni, Yashraj; Bylund, Göran O.; et al.

Enhanced polymerase activity permits efficient synthesis by cancer-Associated DNA polymerase variants at low dNTP levels

Nucleic Acids Research, Oxford University Press 2022, Vol. 50, (14) : 8023-8040

Barbari, Stephanie R.; Beach, Annette K.; Markgren, Joel G.; et al.

Structural consequence of the most frequently recurring cancer-associated substitution in DNA polymerase epsilon

Nature Communications, Nature Publishing Group 2019, Vol. 10

Parkash, Vimal; Kulkarni, Yashraj; ter Beek, Josy; et al.

Structural evidence for an essential Fe–S cluster in the catalytic core domain of DNA polymerase ϵ

Nucleic Acids Research, Oxford University Press 2019, Vol. 47, (11) : 5712-5722

ter Beek, Josy; Parkash, Vimal; Bylund, Göran; et al.

View publications in DiVA

Research groups

Group member

Erik Johansson lab

Research projects

1 January 2022 until 31 December 2024

Kopiering av arvsmassan hos celler