SciLifeLab Umeå and KBC warmly welcome you to participate in the lunch seminar on Wednesday, 27 May:
Presenter:
Rubén Casanova-Sáez, Manager of the C-trap Facility, Department of Plant Physiology, Umeå Plant Science Centre, Umeå University
Description:
The C-Trap facility at KBC provides access to a dual-trap C-Trap Dymo 300 system, an integrated platform that combines optical tweezers, multichannel microfluidics, and fluorescence microscopy. This unique setup enables simultaneous manipulation, visualization, and force measurement of biomolecules with sub-nanometer spatial precision and sub-millisecond temporal resolution. Based on highly focused laser beams, optical tweezers can trap and control microscopic particles, allowing precise application and detection of forces in the picoNewton range at the single-molecule level.
The facility supports real-time investigations of biomolecular interactions under near-physiological conditions, including DNA–protein and RNA–protein binding, protein folding, and conformational dynamics. Integration with confocal fluorescence microscopy enables direct observation of molecular events such as binding, translocation, and structural changes, while the microfluidics system allows rapid exchange of reagents and environmental conditions during experiments. This correlative approach provides simultaneous access to mechanical and biochemical information within a single experiment, overcoming limitations of traditional bulk assays that average out heterogeneous or transient behaviors.
In this seminar, I will introduce the C-Trap instrument and its capabilities, outline the support available to facility users, and present selected examples of research enabled by the C-Trap.
Learn more about the C-Trap Facility at UMU: https://www.umu.se/en/research/infrastructure/c-trap-facility/
Location:
The seminar will be held at Glasburen, in the KBC-building, Linnaeus väg 6, 90736 Umeå (link to Mazemap).
Registration:
Register to book your free lunch by May 25 at 10:00, or drop in on the day to hear the talk with no lunch: Register here.
Online participation (no registration is required):
https://umu.zoom.us/j/61307079123
Meeting ID: 613 0707 9123
More information about the SciLifeLab Umeå/KBC Infrastructure seminar series and the schedule is here.
Organisers: SciLifeLab Umeå and KBC
