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Umeå University
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Image: Mattias Pettersson

Beatrice Melins group

Research group Brain tumors and especially gliomas are tumors that are not easily cured. The most malignant form glioblastoma have very poor survival.

The etiology of brain tumors is not well known, apart from some genetic factors and ionising radiation. Our group tries to understand the underlying causes of glioma and find biomarkers to detect glioma early.Our overall aim is to gain a deeper understanding of the underlying pattern for the glioma architecture subtypes.

We use both cohort and collected case series from several different studies, such as (U-CAN   and  Northern Sweden Health and disease study

Head of research

Beatrice Melin Professor, senior consultant (attending) physician
E-mail
Email
Phone
+46 90 786 61 42

Overview

Participating departments and units at Umeå University

Department of Radiation Sciences, The Biobank Research Unit

Research area

Cancer
Antidepressants and survival in glioma: a registry-based retrospective cohort study
Neuro-Oncology Practice, Oxford University Press 2024, Vol. 11, (2) : 125-131
Edström, Sonja; Numan Hellquist, Barbro; Sandström, Maria; et al.
Altered plasma metabolite levels can be detected years before a glioma diagnosis
JCI Insight, American Society For Clinical Investigation 2023, Vol. 8, (19)
Löding, Sebastian; Andersson, Ulrika; Kaaks, Rudolf; et al.
Assessment of the EarlyCDT-Lung test as an early biomarker of lung cancer in ever-smokers: A retrospective nested case-control study in two prospective cohorts
International Journal of Cancer, John Wiley & Sons 2023, Vol. 152, (9) : 2002-2010
Wu, Wendy Yi-Ying; Haider, Zahra; Feng, Xiaoshuang; et al.
Common germline risk variants impact somatic alterations and clinical features across cancers
Cancer Research, American Association for Cancer Research 2023, Vol. 83, (1) : 20-27
Namba, Shinichi; Saito, Yuki; Kogure, Yasunori; et al.
Defunctioning loop ileostomy in anterior resection for rectal cancer and subsequent renal failure: nationwide population-based study
BJS Open, Oxford University Press 2023, Vol. 7, (3)
Rutegård, Martin; Häggström, Jenny; Back, Erik; et al.
Extended genetic analysis and tumor characteristics in over 4600 women with suspected hereditary breast and ovarian cancer
BMC Cancer, BioMed Central (BMC) 2023, Vol. 23, (1)
Öfverholm, Anna; Törngren, Therese; Rosén, Anna; et al.
Genetic drivers in the natural history of chronic lymphocytic leukemia development as early as 16 years before diagnosis
Blood, Elsevier 2023, Vol. 142, (16) : 1399-1403
Kolijn, P. Martijn; Späth, Florentin; Khouja, Mouhamad; et al.
Extensive study of brain tumor

An Umeå researcher is co-founder of an international team, which has found genetic factors behind glioma.

Knowledge of brain tumour metabolism can improve treatment

Metabolites expression varies greatly between subgroups of malignant brain tumors, cancer researchers show.

Latest update: 2024-01-04