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Computational Analytics Support Platform (CASP)

Research infrastructure CASP is a data analytics platform at Umeå University that supports life science researchers in the analysis of their experimental data, using advanced data-driven tools and strategies.

The Computational Analytics Support Platform description

Our mission is to help life science researchers understand complex chemical and biological systems. This is achieved via the application and development of advanced computer-based modelling tools. CASP’s focus is on the analysis of non-gene related data from a wide array of technologies including downstream ‘omics’, spectroscopy and imaging. Our approach has multiple applications in areas including health, medicine, pharmaceuticals, agriculture and the food science industries. CASP is also an Umeå node and representative of NBIS (National Bioinformatics Infrastructure Sweden).

What we do

At present, huge amounts of data are generated not only in genomics, but also by other modern high-throughput technologies such as ‘omics’ and sensor technologies. The ability to analyze and draw valid conclusions from complex data has become a bottleneck for many life science researchers.

CASP’s aim is to overcome this by becoming the bridge between data and life sciences. We provide researchers with modern data analytics tools within multivariate data analysis, statistics, AI/deep learning, machine learning, bioinformatics and design of experiments, for the analysis of non-gene related data, such as ‘omics’, spectroscopy and imaging data. Ultimately, we hope to provide the missing link that enables projects to go from data to completion. 

How we can help your project

Our main mission is to support researchers deliver high-quality results, by converting complex data into meaningful biological/chemical interpretations relating to their specific scientific question.

Our uniqueness arises from our expertise – we not only understand mathematics, statistics and modelling, but we have wide domain knowledge arising from active engagement in numerous projects in the ‘omics’ area and beyond. Therefore, we are able to ‘jump in’ to your project from day one and provide support every step of the way. This can mean starting from experimental design, quality control of generated data, basic and more in-depth analysis, through to interpretation of results, experimental validation and publishing.

Support and services we provide

We offer different kinds of support for all types of data and research questions:

  • Packaged and customer-specific data analytics services
  • Expanded data analytics support for high-throughput experimental platforms
  • Data science support within interdisciplinary collaborative projects

Our services:

  • Study design
    • Design of Experiments (DOE) / Statistical experimental design
    • Randomized control trial (RCT) studies
  • Data preprocessing, normalization, standardization and scaling
  • Multivariate data analysis
    • Principal Components Analysis (PCA)
    • Partial Least Squares regression analysis (PLS)
    • Orthogonal Partial Least Squares Discriminant Analysis (OPLS-DA)
  • Clustering analysis
    • Heatmaps and k-means clustering
  • Univariate analysis
    • Fold change analysis, T-test analysis, ANOVA, Correlation analysis, Volcano plots
  • Additional services
    • Multiblock data analysis (O2PLS/OnPLS)
    • Classification and feature selection
    • Enrichment analysis
    • AI/deep learning
    • Machine learning
    • Hybrid modelling
    • Biological interpretation of data – pathway analysis
    • Support with manuscript writing

Staff

Johan Trygg, Director

Johan Trygg, Director

Professor at the Department of Chemistry

UmU profile

Kate Bennett, Platform Manager

Kate Bennett, Platform Manager

Research coordinator at the Department of Chemistry

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Izabella Surowiec, Senior Researcher

Izabella Surowiec, Senior Researcher

Senior research engineer at the Department of Chemistry

UmU profile

Hans Stenlund, Senior Data Scientist

Hans Stenlund, Senior Data Scientist

Senior research engineer at the Department of Plant Physiology

UmU profile

David Nilsson, Senior Data Scientist

David Nilsson, Senior Data Scientist

Senior research engineer at Department of Chemistry

UmU profile

Joakim Bygdell, System Developer (NBIS)

Joakim Bygdell

System Developer (NBIS)

NBIS profile

Allison Churcher – Bioinformatician (NBIS)

Allison Churcher

Bioinformatician (NBIS)

NBIS profile

Nina Norgren - Bioinformatician (NBIS)

Nina Norgren

Bioinformatician (NBIS)

NBIS profile

Jeanette Tångrot – Bioinformatician (NBIS)

Jeanette Tångrot

Bioinformatician (NBIS)

NBIS profile

Contact

Kate Bennett 

Platform Manager

katie.bennett@umu.se

UmU profile

Contact request form

Please fill in the contact request form found in the link above and our Platform Manager will be happy to answer any questions you may have.

Our friendly team look forward to supporting you in your projects!