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The DIRECT-study

Understanding Communication and Care Challenges in Hereditary Cancer

Research project Identification of inherited patogenic variants in cancer-predisposing genes in a patient opens the opportunity of predictive testing to genetic relatives at risk. The randomized controlled DIRECT study compared two methods of information transfer and found no difference between them.

We found that offering healthcare-assisted disclosure did not increase the number of relatives seeking genetic counselling. Now the next phase of the DIRECT-study begins. Here we will further explore the long-term effects of a hereditary cancer risk on family communication and quality of life.

Head of project

Anna Rosen
Assoc. prof., sr. consultant (attending) physician, physician
E-mail
Email

Project overview

Project period:

2019-09-02 – 2028-12-31

Participating departments and units at Umeå University

Clinicum Betula, Department of Clinical Sciences, Department of Diagnostics and Intervention, Department of Historical, Philosophical and Religious Studies, Department of Nursing

Research area

Cancer, Philosophy and philosophy of science

External funding

Forte, Swedish Cancer Society, Region Västerbotten, Swedish Research Council, Cancerforskningsfonden Norrland

External funding

Anna Rosén, Institutionen för strålningsvetenskaper
DIRECT IN MEDIA

Read about what the press, media and other organisations write about our research.

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OFFICIAL STUDY DOCUMENTS

The DIRECT study has been ethically approved and registered in clinical trial databases.

Latest update: 2025-11-19