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Umeå University
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Bethany van Guelpen

Research qualifications: Docent

Contact

E-mail
bethany.vanguelpen@umu.se
Phone
+46 90 785 28 09

Works at

Affiliation
Associate professor, consultant (attending) physician at Department of Diagnostics and Intervention Section: Oncology
Location
27C, Målpunkt QC11, NUS, Norrlands universitetssjukhus Umeå universitet, 901 85 Umeå
Dietary patterns, untargeted metabolite profiles and their association with colorectal cancer risk
Scientific Reports, Springer Nature 2024, Vol. 14, (1)
Bodén, Stina; Zheng, Rui; Ribbenstedt, Anton; et al.
Association between pre-diagnostic circulating lipid metabolites and colorectal cancer risk: a nested case–control study in the European Prospective Investigation into Cancer and Nutrition (EPIC)
EBioMedicine, Elsevier 2024, Vol. 101
Harewood, Rhea; Rothwell, Joseph A.; Bešević, Jelena; et al.
Body size and risk of colorectal cancer molecular defined subtypes and pathways: mendelian randomization analyses
EBioMedicine, Elsevier 2024, Vol. 101
Papadimitriou, Nikos; Qu, Conghui; Harrison, Tabitha A.; et al.
Allometric versus traditional body-shape indices and risk of colorectal cancer: a Mendelian randomization analysis
International Journal of Obesity
Rontogianni, Marina O.; Bouras, Emmanouil; Aglago, Elom Kouassivi; et al.
Genetic risk impacts the association of menopausal hormone therapy with colorectal cancer risk
British Journal of Cancer
Tian, Yu; Lin, Yi; Qu, Conghui; et al.
Dietary intake of total, heme and non-heme iron and the risk of colorectal cancer in a European prospective cohort study
British Journal of Cancer, Springer Nature 2023, Vol. 128 : 1529-1540
Aglago, Elom K.; Cross, Amanda J.; Riboli, Elio; et al.
A Genetic Locus within the FMN1/GREM1 Gene Region Interacts with Body Mass Index in Colorectal Cancer Risk
Cancer Research, American Association For Cancer Research (AACR) 2023, Vol. 83, (15) : 2572-2583
Aglago, Elom K.; Kim, Andre; Lin, Yi; et al.
Plasma concentrations of gut hormones acyl ghrelin and peptide YY and subsequent risk of colorectal cancer and molecular tumor subtypes
Cancer Prevention Research, American Association for Cancer Research 2023, Vol. 16, (2) : 75-87
Bodén, Stina; Harbs, Justin; Sundkvist, Anneli; et al.
Genome-wide interaction analysis of folate for colorectal cancer risk
American Journal of Clinical Nutrition, Elsevier 2023, Vol. 118, (5) : 881-891
Bouras, Emmanouil; Kim, Andre E.; Lin, Yi; et al.
Genome-wide interaction study with smoking for colorectal cancer risk identifies novel genetic loci related to tumor suppression, inflammation, and immune response
Cancer Epidemiology, Biomarkers and Prevention, American association for cancer research 2023, Vol. 32, (3) : 315-328
Carreras-Torres, Robert; Kim, Andre E.; Lin, Yi; et al.
Opposing roles by KRAS and BRAF mutation on immune cell infiltration in colorectal cancer: possible implications for immunotherapy
British Journal of Cancer
Edin, Sofia; Gylling, Björn; Li, Xingru; et al.
Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries
Nature Genetics, Nature Publishing Group 2023, Vol. 55 : 89-99
Fernandez-Rozadilla, Ceres; Timofeeva, Maria; Chen, Zhishan; et al.
An epigenome-wide analysis of sex hormone levels and DNA methylation in male blood samples
Epigenetics, Taylor & Francis Group 2023, Vol. 18, (1)
Harbs, Justin; Rinaldi, Sabina; Keski-Rahkonen, Pekka; et al.
Prediagnostic serum calcium concentrations and risk of colorectal cancer development in 2 large European prospective cohorts
American Journal of Clinical Nutrition, Elsevier 2023, Vol. 117, (1) : 33-45
Karavasiloglou, Nena; Hughes, David J.; Murphy, Neil; et al.
Prediagnostic prescription antibiotics use and survival in patients with colorectal cancer: a swedish national register-based study
Cancer Epidemiology, Biomarkers and Prevention, American Association For Cancer Research (AACR) 2023, Vol. 32, (10) : 1391-1401
Lu, Sai San Moon; Rutegård, Martin; Ahmed, Maghfoor; et al.
Prospective and Mendelian randomization analyses on the association of circulating fatty acid binding protein 4 (FABP-4) and risk of colorectal cancer
BMC Medicine, BioMed Central (BMC) 2023, Vol. 21, (1)
Nimptsch, Katharina; Aleksandrova, Krasimira; Pham, Thu Thi; et al.
Association of pre-diagnostic physical exercise and peri-diagnostic body composition with mortality in non-metastatic colorectal cancer
International Journal of Colorectal Disease, Springer Nature 2023, Vol. 38, (1)
Renman, David; van Guelpen, Bethany; Anderson, Fredrick; et al.
Circulating amino acid levels and colorectal cancer risk in the European Prospective Investigation into Cancer and Nutrition and UK Biobank cohorts
BMC Medicine, BioMed Central (BMC) 2023, Vol. 21, (1)
Rothwell, Joseph A.; Bešević, Jelena; Dimou, Niki; et al.
Validation of a genetic-enhanced risk prediction model for colorectal cancer in a large community-based cohort
Cancer Epidemiology, Biomarkers and Prevention, American association for cancer research 2023, Vol. 32, (3) : 353-362
Su, Yu-Ru; Sakoda, Lori C.; Jeon, Jihyoun; et al.
Metabolically (un)healthy obesity and risk of obesity-related cancers: a pooled study
Journal of the National Cancer Institute, Oxford University Press 2023, Vol. 115, (4) : 456-467
Sun, Ming; Fritz, Josef; Häggström, Christel; et al.
CTH G1208T and MTHFR A1298C polymorphisms are associated with a higher risk of a first myocardial infarction with fatal outcome among women
Drug Metabolism and Personalized Therapy, De Gruyter Open 2023, Vol. 38, (1) : 57-63
Söderström, Elisabet; Andersson, Jonas; Söderberg, Stefan; et al.
Combining Asian and European genome-wide association studies of colorectal cancer improves risk prediction across racial and ethnic populations
Nature Communications, Springer Nature 2023, Vol. 14, (1)
Thomas, Minta; Su, Yu-Ru; Rosenthal, Elisabeth A.; et al.
Prognostic role of detailed colorectal location and tumor molecular features: analyses of 13,101 colorectal cancer patients including 2994 early-onset cases
Journal of gastroenterology, Springer 2023, Vol. 58 : 229-245
Ugai, Tomotaka; Akimoto, Naohiko; Haruki, Koichiro; et al.
Molecular characteristics of early-onset colorectal cancer according to detailed anatomical locations: comparison with later-onset cases
American Journal of Gastroenterology, Wolters Kluwer 2023, Vol. 118, (4) : 712-726
Ugai, Tomotaka; Haruki, Koichiro; Harrison, Tabitha A.; et al.
Untargeted plasma metabolomics and risk of colorectal cancer: an analysis nested within a large-scale prospective cohort
Cancer & Metabolism, BioMed Central (BMC) 2023, Vol. 11, (1)
Vidman, Linda; Zheng, Rui; Bodén, Stina; et al.
Observational and genetic associations between cardiorespiratory fitness and cancer: a UK Biobank and international consortia study
British Journal of Cancer
Watts, Eleanor L.; Gonzales, Tomas I.; Strain, Tessa; et al.
Dietary fatty acids and endometrial cancer risk within the European Prospective Investigation into Cancer and Nutrition
BMC Cancer, BioMed Central (BMC) 2023, Vol. 23, (1)
Yammine, S.G.; Huybrechts, I.; Biessy, C.; et al.
Circulating Sex Hormone Levels and Colon Cancer Risk in Men: A Nested Case–Control Study and Meta-Analysis
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research 2022, Vol. 31, (4) : 793-803
Harbs, Justin; Rinaldi, Sabina; Gicquiau, Audrey; et al.
Diabetes mellitus in relation to colorectal tumor molecular subtypes: a pooled analysis of more than 9000 cases
International Journal of Cancer, John Wiley & Sons 2022, Vol. 151, (3) : 348-360
Harlid, Sophia; van Guelpen, Bethany; Qu, Conghui; et al.
Cancer worry distribution and willingness to undergo colonoscopy at three levels of hypothetical cancer risk - a population-based survey in Sweden
Cancers, MDPI 2022, Vol. 14, (4)
Hawranek, Carolina; Maxon, Johan; Andersson, Andreas; et al.
Beyond GWAS of Colorectal Cancer: Putative Causal Variant for the 10q24.2 Region
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research 2022, Vol. 31, (5) : 1077-1089
Jordahl, Kristina M.; Shcherbina, Anna; Harlid, Sophia; et al.
Genome-wide association study identifies tumor anatomical site-specific risk variants for colorectal cancer survival
Scientific Reports, Nature Publishing Group 2022, Vol. 12, (1)
Labadie, Julia D.; Savas, Sevtap; Harrison, Tabitha A.; et al.
Antibiotics Use and Subsequent Risk of Colorectal Cancer: A Swedish Nationwide Population-Based Study
Journal of the National Cancer Institute, Oxford University Press 2022, Vol. 114, (1) : 38-46
Lu, Sai San Moon; Mohammed, Zahraa; Häggström, Christel; et al.
Associations between Glycemic Traits and Colorectal Cancer: A Mendelian Randomization Analysis
Journal of the National Cancer Institute, Oxford University Press (OUP) 2022, Vol. 114, (5) : 740-752
Murphy, Neil; Song, Mingyang; Papadimitriou, Nikos; et al.
Pre-diagnostic C-reactive protein concentrations, CRP genetic variation and mortality among individuals with colorectal cancer in Western European populations
BMC Cancer, BioMed Central (BMC) 2022, Vol. 22, (1)
Nimptsch, Katharina; Aleksandrova, Krasimira; Fedirko, Veronika; et al.
Metabolic signatures of healthy lifestyle patterns and colorectal cancer risk in a European cohort
Clinical Gastroenterology and Hepatology, Elsevier 2022, Vol. 20, (5) : e1061-e1082
Rothwell, Joseph A.; Murphy, Neil; Bešević, Jelena; et al.
Large-scale Integrated Analysis of Genetics and Metabolomic Data Reveals Potential Links Between Lipids and Colorectal Cancer Risk
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research 2022, Vol. 31, (6) : 1216-1226
Shu, Xiang; Chen, Zhishan; Long, Jirong; et al.
Genome-Wide Interaction Analysis of Genetic Variants With Menopausal Hormone Therapy for Colorectal Cancer Risk
Journal of the National Cancer Institute, Oxford University Press 2022, Vol. 114, (8) : 1135-1148
Tian, Yu; Kim, Andre E.; Bien, Stephanie A.; et al.
Development and validation of a lifestyle-based model for colorectal cancer risk prediction: the LiFeCRC score
BMC Medicine, BioMed Central 2021, Vol. 19, (1)
Aleksandrova, Krasimira; Reichmann, Robin; Kaaks, Rudolf; et al.
Smoking Behavior and Prognosis after Colorectal Cancer Diagnosis: A Pooled Analysis of 11 Studies
JNCI Cancer Spectrum, Oxford University Press 2021, Vol. 5, (5)
Alwers, Elizabeth; Carr, Prudence R.; Banbury, Barbara; et al.
Prevalent diabetes and risk of total, colorectal, prostate and breast cancers in an ageing population: meta-analysis of individual participant data from cohorts of the CHANCES consortium
British Journal of Cancer, Nature Publishing Group 2021, Vol. 124, (11) : 1882-1890
Amadou, Amina; Freisling, Heinz; Jenab, Mazda; et al.
Prediagnostic blood selenium status and mortality among patients with colorectal cancer in western european populations
Biomedicines, MDPI 2021, Vol. 9, (11)
Baker, Jacqueline Roshelli; Umesh, Sushma; Jenab, Mazda; et al.
Causal effects of lifetime smoking on breast and colorectal cancer risk: Mendelian randomization study
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research (AACR) 2021, Vol. 30, (5) : 953-964
Dimou, Niki; Yarmolinsky, James; Bouras, Emmanouil; et al.
Identifying Novel Susceptibility Genes for Colorectal Cancer Risk From a Transcriptome-Wide Association Study of 125,478 Subjects
Gastroenterology, Saunders Elsevier 2021, Vol. 160, (4) : 1164-1178
Guo, Xingyi; Lin, Weiqiang; Wen, Wanqing; et al.
Work-Related Stress Was Not Associated with Increased Cancer Risk in a Population-Based Cohort Setting
Cancer Epidemiology, Biomarkers and Prevention, American Association for Cancer Research 2021, Vol. 31, (1) : 51-57
Hadrévi, Jenny; Myte, Robin; Olsson, Tommy; et al.
Risk‐predictive and diagnostic biomarkers for colorectal cancer: a systematic review of studies using pre‐diagnostic blood samples collected in prospective cohorts and screening settings
Cancers, MDPI 2021, Vol. 13, (17)
Harlid, Sophia; Gunter, Marc J.; van Guelpen, Bethany
A two-tiered targeted proteomics approach to identify pre-diagnostic biomarkers of colorectal cancer risk
Scientific Reports, Springer Nature 2021, Vol. 11, (1)
Harlid, Sophia; Harbs, Justin; Myte, Robin; et al.
Genetic architectures of proximal and distal colorectal cancer are partly distinct
Gut, BMJ Publishing Group Ltd 2021, Vol. 70, (7) : 1325-1334
Huyghe, Jeroen R; Harrison, Tabitha A; Bien, Stephanie A; et al.
Metabolic signatures of greater body size and their associations with risk of colorectal and endometrial cancers in the European Prospective Investigation into Cancer and Nutrition
BMC Medicine, BioMed Central 2021, Vol. 19, (1)
Kliemann, Nathalie; Viallon, Vivian; Murphy, Neil; et al.
Endogenous Circulating Sex Hormone Concentrations and Colon Cancer Risk in Postmenopausal Women: A Prospective Study and Meta-Analysis
JNCI cancer spectrum, Oxford University Press 2021, Vol. 5, (6)
Mori, Nagisa; Keski-Rahkonen, Pekka; Gicquiau, Audrey; et al.
View publications in DiVA

Research groups

Head of research
Bethany van Guelpen Lab
Group member
Arktisk kost, hälsa och hållbarhet

Research projects

1 January 2022 until 31 December 2024
Etiology, risk prediction and early detection of colorectal cancer
1 January 2014 until 26 November 2030
The role of diet in diseases related to inflammation