Lars-Owe Koskinen

Professor of Neurosurgery

0000-0003-3528-8502

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Works as

Professor at Department of Clinical Sciences Section: Neurosciences

Norrlands universitetssjukhus, Umeå universitet, Klinisk vetenskap Umeå universitet, Klinisk vetenskap, 901 85 Umeå

An optimized ensemble search approach for classification of higher-level gait disorder using brain magnetic resonance images

Computers in Biology and Medicine, Elsevier 2025, Vol. 184

Mogensen, Klara; Guarrasi, Valerio; Larsson, Jenny; et al.

Complications following endoscopic transsphenoidal surgery for pituitary adenoma: special focus on intrasellar pressure

Acta Neurochirurgica, Springer Nature 2025, Vol. 167

Simander, Gabriel; Eriksson, Per Olof; Viirola, Sara; et al.

Cerebral arterial stiffness is linked to white matter hyperintensities and perivascular spaces in older adults: a 4D flow MRI study

Journal of Cerebral Blood Flow and Metabolism, Sage Publications 2024, Vol. 44, (8) : 1343-1351

Björnfot, Cecilia; Eklund, Anders; Larsson, Jenny; et al.

Classification and characterization of traumatic brain injuries in the northern region of sweden

Journal of Clinical Medicine, MDPI 2024, Vol. 13, (1)

Magnusson, Beatrice M.; Koskinen, Lars-Owe D.

Serum neurofilament light as a predictor of outcome in subarachnoid haemorrhage

Acta Neurochirurgica, Springer 2023, Vol. 165, (10) : 2793-2800

Johansson, Conny; Aineskog, Helena; Koskinen, Lars-Owe D.; et al.

Prognostic models for global functional outcome and post-concussion symptoms following mild traumatic brain injury: a collaborative european neurotrauma effectiveness research in traumatic brain injury (CENTER-TBI) study

Journal of Neurotrauma, Mary Ann Liebert 2023, Vol. 40, (15-16) : 1651-1670

Mikolić, Ana; Steyerberg, Ewout W.; Polinder, Suzanne; et al.

Computed tomography lesions and their association with global outcome in young people with mild traumatic brain injury

Journal of Neurotrauma, Mary Ann Liebert 2023, Vol. 40, (11-12) : 1243-1254

Riemann, Lennart; Mikolic, Ana; Maas, Andrew; et al.

Modern handläggning minimerar följder av traumatisk hjärnskada: behandlingsriktlinjer har tydligt reducerat mortaliteten: [Treatment of traumatic brain injury in the acute setting - an overview]

Läkartidningen, Läkartidningen Förlag 2023, Vol. 120, (4-5)

Rostami, Elham; Ginstman, Fredrik; Ljungqvist, Johan; et al.

Intrasellar pressure is related to endocrine disturbances in patients with pituitary tumors

World Neurosurgery, Elsevier 2023, Vol. 175 : e344-e351

Simander, Gabriel; Dahlqvist, Per; Oja, Louise; et al.

Comparative effectiveness of decompressive craniectomy versus craniotomy for traumatic acute subdural hematoma (CENTER-TBI): an observational cohort study

eClinicalMedicine, Elsevier 2023, Vol. 63

van Essen, Thomas A; van Erp, Inge A M; Lingsma, Hester F; et al.

Serum S100B correlates with health-related quality of life and functional outcome in patients at 1 year after aneurysmal subarachnoid haemorrhage

Acta Neurochirurgica, Springer Nature 2022, Vol. 164, (8) : 2209-2218

Aineskog, Helena; Johansson, Conny; Nilsson, Robert; et al.

Measurement invariance of six language versions of the post-traumatic stress disorder checklist for DSM-5 in civilians after traumatic brain injury

Scientific Reports, Springer Nature 2022, Vol. 12, (1)

Bockhop, Fabian; Zeldovich, Marina; Cunitz, Katrin; et al.

Extended Coagulation Profiling in Isolated Traumatic Brain Injury: A CENTER-TBI Analysis

Neurocritical Care, Springer 2022, Vol. 36, (3) : 927-941

Böhm, Julia K.; Schaeben, Victoria; Schäfer, Nadine; et al.

Can We Cluster ICU Treatment Strategies for Traumatic Brain Injury by Hospital Treatment Preferences?

Neurocritical Care, Springer 2022, Vol. 36, (3) : 846-856

Ceyisakar, Iris E.; Huijben, Jilske A.; Maas, Andrew I. R.; et al.

Effect of frailty on 6-month outcome after traumatic brain injury: a multicentre cohort study with external validation

Lancet Neurology, Elsevier 2022, Vol. 21, (2) : 153-162

Galimberti, Stefania; Graziano, Francesca; Maas, Andrew I. R.; et al.

Rehabilitation and outcomes after complicated vs uncomplicated mild TBI: results from the CENTER-TBI study

BMC Health Services Research, BioMed Central (BMC) 2022, Vol. 22, (1)

Howe, Emilie Isager; Zeldovich, Marina; Andelic, Nada; et al.

Correlation of Cerebral and Subcutaneous Glycerol in Severe Traumatic Brain Injury and Association with Tissue Damage

Neurocritical Care, Springer 2022, Vol. 36 : 993-1001

Hägglund, Linda; Olivecrona, Magnus; Koskinen, Lars-Owe D.

Serum Levels of Myo-inositol Predicts Clinical Outcome 1 Year After Aneurysmal Subarachnoid Hemorrhage

Neurosurgery, Lippincott Williams & Wilkins 2022, Vol. 91, (5) : 790-798

Johansson, Conny; Koskinen, Lars-Owe D.; Sjöberg, Rickard L.; et al.

A genome-wide association study of outcome from traumatic brain injury

EBioMedicine, Elsevier 2022, Vol. 77

Kals, Mart; Kunzmann, Kevin; Parodi, Livia; et al.

A prospective observational cohort study of traumatic brain injury in the northern region of Sweden

Brain Injury, Taylor & Francis 2022, Vol. 36, (2) : 191-198

Magnusson, Beatrice M.; Isaksson, Emil; Koskinen, Lars-Owe D.

Discrepancy between disability and reported well-being after traumatic brain injury

Journal of Neurology, Neurosurgery and Psychiatry, BMJ Publishing Group Ltd 2022, Vol. 93, (7) : 785-96

Retel Helmrich, Isabel Rosalie Arianne; van Klaveren, David; Andelic, Nada; et al.

High arterial oxygen levels and supplemental oxygen administration in traumatic brain injury: insights from CENTER-TBI and OzENTER-TBI.

Intensive Care Medicine, Springer 2022, Vol. 48, (12) : 1709-1725

Rezoagli, Emanuele; Petrosino, Matteo; Rebora, Paola; et al.

Concomitant spine trauma in patients with traumatic brain injury: Patient characteristics and outcomes

Frontiers in Neurology, Frontiers Media S.A. 2022, Vol. 13

Riemann, Lennart; Alhalabi, Obada T; Unterberg, Andreas W; et al.

Intrasellar pressure in patients with pituitary adenoma – relation to tumour size and growth pattern

BMC Neurology, BioMed Central 2022, Vol. 22, (1)

Simander, Gabriel; Eriksson, Per Olof; Lindvall, Peter; et al.

Vibrational spectroscopy for the triage of traumatic brain injury computed tomography priority and hospital admissions

Journal of Neurotrauma, Mary Ann Liebert 2022, Vol. 39, (11-12) : 773-783

Theakstone, Ashton G.; Brennan, Paul M.; Ashton, Katherine; et al.

Serum metabolome associated with severity of acute traumatic brain injury

Nature Communications, Nature Research 2022, Vol. 13, (1)

Thomas, Ilias; Dickens, Alex M.; Posti, Jussi P.; et al.

Health care utilization and outcomes in older adults after Traumatic Brain Injury: a CENTER-TBI study

Injury, Elsevier 2022, Vol. 53, (8) : 2774-2782

van der Vlegel, Marjolein; Mikolić, Ana; Lee Hee, Quentin; et al.

Surgery versus conservative treatment for traumatic acute subdural haematoma: a prospective, multicentre, observational, comparative effectiveness study

Lancet Neurology, Elsevier 2022, Vol. 21, (7) : 620-631

van Essen, Thomas A.; Lingsma, Hester F.; Pisică, Dana; et al.

Neurocognitive correlates of probable posttraumatic stress disorder following traumatic brain injury

Brain & spine, Elsevier 2022, Vol. 2

Van Praag, Dominique L. G.; Wouters, Kristien; Van Den Eede, Filip; et al.

Comparative effectiveness of intracranial hypertension management guided by ventricular versus intraparenchymal pressure monitoring: a CENTER-TBI study

Acta Neurochirurgica, Springer 2022, Vol. 164, (7) : 1693-1705

Volovici, Victor; Pisică, Dana; Gravesteijn, Benjamin Y.; et al.

Probabilistic prediction of increased intracranial pressure in patients with severe traumatic brain injury

Scientific Reports, Nature Publishing Group 2022, Vol. 12, (1)

Wijayatunga, Priyantha; Koskinen, Lars-Owe D.; Sundström, Nina

Tailoring multi-dimensional outcomes to level of functional recovery after traumatic brain injury

Journal of Neurotrauma, Mary Ann Liebert 2022, Vol. 39, (19-20) : 1363-1381

Wilson, Lindsay; Horton, Lindsay; Polinder, Suzanne; et al.

Clustering identifies endotypes of traumatic brain injury in an intensive care cohort: a CENTER-TBI study

Critical Care, BioMed Central (BMC) 2022, Vol. 26, (1)

Åkerlund, Cecilia A. I.; Holst, Anders; Stocchetti, Nino; et al.

Frequency of fatigue and its changes in the first 6 months after traumatic brain injury: results from the CENTER-TBI study

Journal of Neurology, Springer 2021, Vol. 268, (1) : 61-73

Andelic, Nada; Røe, Cecilie; Brunborg, Cathrine; et al.

Prediction model for intracranial hypertension demonstrates robust performance during external validation on the CENTER-TBI dataset

Intensive Care Medicine, Springer 2021, Vol. 47, (1) : 124-126

Carra, Giorgia; Güiza, Fabian; Depreitere, Bart; et al.

Management of arterial partial pressure of carbon dioxide in the first week after traumatic brain injury: results from the CENTER-TBI study

Intensive Care Medicine, Springer 2021, Vol. 47, (9) : 961-973

Citerio, Giuseppe; Robba, Chiara; Rebora, Paola; et al.

Outcome Prediction after Moderate and Severe Traumatic Brain Injury: External Validation of Two Established Prognostic Models in 1742 European Patients

Journal of Neurotrauma, Mary Ann Liebert 2021, Vol. 38, (10) : 1377-1388

Dijkland, Simone A.; Retel Helmrich, Isabel R. A.; Nieboer, Daan; et al.

Risk factors for developing subdural hematoma: a registry-based study in 1457 patients with shunted idiopathic normal pressure hydrocephalus

Journal of Neurosurgery, American Association of Neurological Surgeons 2021, Vol. 134, (2) : 668-677

Gasslander, Johan; Sundström, Nina; Eklund, Anders; et al.

Missing Data in Prediction Research: A Five-Step Approach for Multiple Imputation, Illustrated in the CENTER-TBI Study

Journal of Neurotrauma, Mary Ann Liebert 2021, Vol. 38, (13) : 1842-1857

Gravesteijn, Benjamin Yaël; Sewalt, Charlie Aletta; Venema, Esmee; et al.

Questionnaires vs Interviews for the Assessment of Global Functional Outcomes After Traumatic Brain Injury

JAMA Network Open, American Medical Association 2021, Vol. 4, (11)

Horton, Lindsay; Rhodes, Jonathan; Menon, David K.; et al.

Use and impact of high intensity treatments in patients with traumatic brain injury across Europe: a CENTER-TBI analysis

Critical Care, BioMed Central (BMC) 2021, Vol. 25, (1)

Huijben, Jilske A.; Dixit, Abhishek; Stocchetti, Nino; et al.

Prediction of Global Functional Outcome and Post-Concussive Symptoms after Mild Traumatic Brain Injury: External Validation of Prognostic Models in the Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) Study

Journal of Neurotrauma, Mary Ann Liebert 2021, Vol. 38, (2) : 196-209

Mikolić, Ana; Polinder, Suzanne; Steyerberg, Ewout W.; et al.

Differences between Men and Women in Treatment and Outcome after Traumatic Brain Injury

Journal of Neurotrauma, Mary Ann Liebert 2021, Vol. 38, (2) : 235-251

Mikolić, Ana; van Klaveren, David; Oude Groeniger, Joost; et al.

The Effect of Temperature Increases on Brain Tissue Oxygen Tension in Patients with Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Substudy

Therapeutic Hypothermia and Temperature Management, Mary Ann Liebert 2021, Vol. 11, (2) : 122-131

Rass, Verena; Huber, Lukas; Ianosi, Bogdan-Andrei; et al.

Persistent postconcussive symptoms in children and adolescents with mild traumatic brain injury receiving initial head computed tomography

Journal of Neurosurgery: Pediatrics, American Association of Neurological Surgeons 2021, Vol. 27, (5) : 538-547

Riemann, Lennart; Voormolen, Daphne C.; Rauen, Katrin; et al.

Primary versus early secondary referral to a specialized neurotrauma center in patients with moderate/severe traumatic brain injury: a CENTER TBI study

Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine, BioMed Central (BMC) 2021, Vol. 29, (1)

Sewalt, Charlie Aletta; Gravesteijn, Benjamin Yaël; Menon, David; et al.

Psychometric Characteristics of the Patient-Reported Outcome Measures Applied in the CENTER-TBI Study

Journal of Clinical Medicine, MDPI 2021, Vol. 10, (11)

Steinbuechel, Nicole von; Rauen, Katrin; Bockhop, Fabian; et al.

Refeeding syndrome: multimodal monitoring and clinical manifestation of an internal severe neurotrauma

Journal of clinical monitoring and computing, Springer 2021, Vol. 35 : 569-576

Sundström, Nina; Brorsson, Camilla; Karlsson, Marcus; et al.

Occurrence and timing of withdrawal of life-sustaining measures in traumatic brain injury patients: a CENTER-TBI study

Intensive Care Medicine, Springer Science+Business Media B.V. 2021, Vol. 47, (10) : 1115-1129

van Veen, Ernest; van der Jagt, Mathieu; Citerio, Giuseppe; et al.

Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study

Lancet Neurology, Elsevier 2021, Vol. 20, (8) : 627-638

Wiegers, Eveline Janine Anna; Lingsma, Hester Floor; Huijben, Jilske Antonia; et al.

View publications in DiVA

Research groups

Head of research

Lars-Owe Koskinen lab

Research projects

1 January 2014 until 31 December 2016

Microgravity physiologi and intracranial pressure for understanding spaceflight induced intracranial hypertension and vision alteration