Skip to content
printicon
Staff photo Sjoerd Wanrooij

Sjoerd Wanrooij

Molecular mechanism of DNA repair and replication in human mitochondria

Contact

E-mail

Works at

Affiliation
Location
KB. A6, Campus, Umeå Umeå universitet, 901 87 Umeå

Human mitochondrial DNA (mtDNA) encodes for genes that are essential for proper energy production. Loss of mtDNA function results in a broad range of genetic human disorders, and it is increasingly recognized as a significant factor in common disorders such as neurodegeneration. Our group investigates detailed molecular mechanisms of mitochondrial DNA replication and repair in order to better understand the underlying causes of such disease states.

2019
Angewandte Chemie International Edition, Vol. 58, (5) : 1417-1421
Moodie, Lindon W. K.; Hubert, Madlen; Zhou, Xin; et al.
2018
Nucleic Acids Research, Oxford University Press 2018, Vol. 46, (18) : 9471-9483
Al-Behadili, Ali; Uhler, Jay P.; Berglund, Anna-Karin; et al.
2018
PLoS Genetics, Public library science 2018, Vol. 14, (3)
Forslund, Josefin M. E.; Pfeiffer, Annika; Stojkovič, Gorazd; et al.
2018
Bioessays, Wiley-Blackwell 2018, Vol. 40, (9)
Pohjoismäki, Jaakko L. O.; Forslund, Josefin; Goffart, Steffi; et al.
2017
PLoS ONE, PUBLIC LIBRARY SCIENCE 2017, Vol. 12, (9)
Boldinova, Elizaveta O.; Stojkovic, Gorazd; Khairullin, Rafil; et al.
2017
International Journal of Molecular Sciences, MDPI AG 2017, Vol. 18, (7)
Boldinova, Elizaveta O.; Wanrooij, Paulina H.; Shilkin, Evgeniy S.; et al.
2017
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2017, Vol. 114, (43) : 11398-11403
Torregrosa-Muñumer, Rubén; Forslund, Josefin M. E.; Goffart, Steffi; et al.
2017
Proceedings of the National Academy of Sciences of the United States of America, National Academy of Sciences 2017, Vol. 114, (47) : 12466-12471
Wanrooij, Paulina H.; Engqvist, Martin K. M.; Forslund, Josefin M. E.; et al.
2016
Scientific Reports, Vol. 6
Stojkovic, Gorazd; Makarova, Alena V.; Wanrooij, Paulina H.; et al.
2015
Biochimica et Biophysica Acta. Molecular Cell Research, Vol. 1853, (10) : 2580-2591
Al-Furoukh, Natalie; Ianni, Alessandro; Nolte, Hendrik; et al.
2014
PLOS Genetics, Vol. 10, (12) : e1004832-
Miralles Fusté, Javier; Shi, Yonghong; Wanrooij, Sjoerd; et al.

Research groups

Head of research
Sjoerd Wanrooij