Souvik Sarkar

Contact

Works as

Other position at Department of Chemistry

KB.C4, Linnaeus väg 10, C4-39-07 Umeå universitet, 901 87 Umeå

Publications Publications

Metabolic rewiring of isoniazid sensitivity in Mycobacterium tuberculosis

Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences (PNAS) 2025, Vol. 122, (36)

Wang, Erin R.; Cho, Kevin; Harrison, Gregory A.; et al.

Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug-resistant Mycobacterium tuberculosis

mBio, American Society for Microbiology 2024, Vol. 15, (3)

Harrison, Gregory A.; Wang, Erin R.; Cho, Kevin; et al.

Synthesis of three-dimensional ring fused heterocycles by a selective [4 + 2] cycloaddition between bicyclic thiazolo 2-pyridones and arynes

Journal of Organic Chemistry, American Chemical Society (ACS) 2024, Vol. 89, (1) : 731-739

Sarkar, Souvik; Singh, Pardeep; Edin, Simon; et al.

Design, synthesis, and evaluation of novel Δ²-thiazolino 2-pyridone derivatives that potentiate isoniazid activity in an isoniazid-resistant mycobacterium tuberculosis mutant

Journal of Medicinal Chemistry, American Chemical Society (ACS) 2023, Vol. 66, (16) : 11056-11077

Sarkar, Souvik; Mayer Bridwell, Anne E.; Good, James A. D.; et al.

A highly substituted ring-fused 2-pyridone compound targeting PrfA and the efflux regulator BrtA in listeria monocytogenes

mBio, American Society for Microbiology 2023, Vol. 14, (3)

Tükenmez, Hasan; Singh, Pardeep; Sarkar, Souvik; et al.

Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics

Proceedings of the National Academy of Sciences of the United States of America, PNAS 2022, Vol. 119, (43)

Nye, Taylor M.; Tükenmez, Hasan; Singh, Pardeep; et al.

An efficient and scalable synthesis of thiazolo ring fused 2-pyridones using flow chemistry

ARKIVOC, Arkat 2021, Vol. 2020, (7) : 365-378

Cairns, Andrew G.; Sarkar, Souvik; Singh, Pardeep; et al.

Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones

Journal of Organic Chemistry, American Chemical Society (ACS) 2021, Vol. 86, (23) : 16582-16592

Tyagi, Mohit; Adolfsson, Dan E.; Singh, Pardeep; et al.

Mycobacterium tuberculosis Rv3160c is a TetR-like transcriptional repressor that regulates expression of the putative oxygenase Rv3161c

Scientific Reports, Springer Nature 2021, Vol. 11, (1)

Tükenmez, Hasan; Sarkar, Souvik; Anoosheh, Saber; et al.

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