Thomas Sandström

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Professor, senior consultant (attending) physician at Department of Public Health and Clinical Medicine Units: Section of Medicine, Pulmonary Medicine

By 10, lungmedicin, Norrlands Universitetssjukhus

A multi-omics approach to delineate sputum microbiome-associated asthma inflammatory phenotypes

European Respiratory Journal, European Respiratory Society 2022, Vol. 59, (1)

Abdel-Aziz, Mahmoud I.; Vijverberg, Susanne J.H.; Neerincx, Anne H.; et al.

Determinants of severe asthma: a long-term cohort study in northern Sweden

Journal of Asthma and Allergy, Dove press 2022, Vol. 15 : 1429-1439

Backman, Helena; Stridsman, Caroline; Hedman, Linnea; et al.

Cold air exposure at -15 °C induces more airway symptoms and epithelial stress during heavy exercise than rest without aggravated airway constriction

European Journal of Applied Physiology, Springer 2022, Vol. 122, (12) : 2533-2544

Eriksson, Linda; Sköndal, Åsa; Tufvesson, Ellen; et al.

TUBE project: Transport-derived ultrafines and the brain effects

International Journal of Environmental Research and Public Health, MDPI 2022, Vol. 19, (1)

Martikainen, Maria-Viola; Aakko-Saksa, Päivi; Broek, Lenie van den; et al.

Plasma proteins elevated in severe asthma despite oral steroid use and unrelated to Type-2 inflammation

European Respiratory Journal, European Respiratory Society 2022, Vol. 59, (2)

Sparreman Mikus, Maria; Kolmert, Johan; Andersson, Lars I.; et al.

An experimental exposure study revealing composite airway effects of physical exercise in a subzero environment

International Journal of Circumpolar Health, Taylor & Francis 2021, Vol. 80, (1)

Eriksson, Linda; Schagatay, Filip; Tufvesson, Ellen; et al.

Acute Exposure to Diesel Exhaust Increases Muscle Sympathetic Nerve Activity in Humans

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Wiley-Blackwell Publishing Inc. 2021, Vol. 10, (10)

Rankin, Gregory D.; Kabéle, Mikael; Brown, Rachael; et al.

Acute cardiovascular effects of controlled exposure to dilute Petrodiesel and biodiesel exhaust in healthy volunteers: a crossover study

Particle and Fibre Toxicology, BioMed Central 2021, Vol. 18, (1)

Unosson, Jon; Kabele, Mikael; Boman, Christoffer; et al.

Airway Elastin is increased in severe asthma and relates to proximal wall area: histological and computed tomography findings from the U-BIOPRED severe asthma study

Clinical and Experimental Allergy, John Wiley & Sons 2021, Vol. 51, (2) : 296-304

Wilson, Susan J.; Ward, Jonathan A.; Pickett, Helen M.; et al.

FEV₁ decline in relation to blood eosinophils and neutrophils in a population-based asthma cohort

The World Allergy Organization journal, Elsevier 2020, Vol. 13, (3)

Backman, Helena; Lindberg, Anne; Hedman, Linnea; et al.

NORDSTAR: paving the way for a new era in asthma research

European Respiratory Journal, European Respiratory Society 2020, Vol. 55, (4)

Geale, Kirk; Darabi, Hatef; Lindh, Maria; et al.

Do Plasticizers within the Indoor Environment Increase Airway Allergen Responsiveness?

American Journal of Respiratory and Critical Care Medicine, American Thoracic Society 2020, Vol. 202, (5) : 639-640

Mudway, Ian S.; Sandström, Thomas

Brake dust exposure exacerbates inflammation and transiently compromises phagocytosis in macrophages

Metallomics, Royal Society of Chemistry 2020, Vol. 12, (3) : 371-386

Selley, Liza; Schuster, Linda; Marbach, Helene; et al.

Severe asthma: A population study perspective

Clinical and Experimental Allergy, John Wiley & Sons 2019, Vol. 49, (6) : 819-828

Backman, Helena; Jansson, Sven-Arne; Stridsman, Caroline; et al.

American Journal of Respiratory and Critical Care Medicine, AMER THORACIC SOC 2019, Vol. 200, (5) : 523-524

Bosson, Jenny A.; Mudway, Ian S.; Sandström, Thomas

Identification and prospective stability of electronic nose (eNose)-derived inflammatory phenotypes in patients with severe asthma

Journal of Allergy and Clinical Immunology, Elsevier 2019, Vol. 143, (5) : 1811-1820.e7

Brinkman, Paul; Wagener, Ariane H.; Hekking, Pieter-Paul; et al.

Effect and feasibility of non-linear periodized resistance training in people with COPD: study protocol for a randomized controlled trial

Trials, BioMed Central 2019, Vol. 20, (1)

Frykholm, Erik; Klijn, Peter; Saey, Didier; et al.

Wood smoke effects on epithelial cell lines and human airway cells

European Respiratory Journal, European Respiratory Society Journals 2019, Vol. 54

Hansson, Alva; Rankin, Gregory; Uski, Oskari; et al.

Epithelial IL-6 trans-signaling defines a new asthma phenotype with increased airway inflammation

Journal of Allergy and Clinical Immunology, Elsevier 2019, Vol. 143, (2) : 577-590

Jevnikar, Zala; Ostling, Jorgen; Calven, Jenny; et al.

Contribution of airway eosinophils in airway wall remodeling in asthma: Role of MMP-10 and MET

Allergy. European Journal of Allergy and Clinical Immunology, John Wiley & Sons 2019, Vol. 74, (6) : 1102-1112

Kuo, Chih-Hsi S.; Pavlidis, Stelios; Zhu, Jie; et al.

Small airways effects of exposure to wood smoke

European Respiratory Journal, Sheffield: European Respiratory Society Journals 2019, Vol. 54

Muala, Ala; Österdahl, Rebecka; Sehlstedt, Maria; et al.

Epithelial dysregulation in obese severe asthmatics with gastro-oesophageal reflux

European Respiratory Journal, Vol. 53, (6)

Perotin, Jeanne-Marie; Schofield, James P. R.; Wilson, Susan J.; et al.

Subtypes of eosinophilic asthma with discrete gene pathway phenotypes

European Respiratory Journal, European Respiratory Society Journals 2019, Vol. 54

Perotin-Collard, Jeanne-Marie; Schofield, James Pr; Nicholas, Ben; et al.

Exposure to wood smoke induced activation of lymphocyte subtypes in peripheral blood

European Respiratory Journal, Sheffield: European Respiratory Society Journals 2019, Vol. 54

Pourazar, Jamshid; Sehlstedt, Maria; Rankin, Gregory; et al.

Stratification of asthma phenotypes by airway proteomic signatures

Journal of Allergy and Clinical Immunology, Elsevier 2019, Vol. 144, (1) : 70-82

Schofield, James P. R.; Burg, Dominic; Nicholas, Ben; et al.

Wood smoke exposure induces the activation of bronchoalveolar lavage lymphocytes

European Respiratory Journal, European Respiratory Society Journals 2019, Vol. 54

Sehlstedt, Maria; Muala, Ala; Pourazar, Jamshid; et al.

Treatable traits in the European U-BIOPRED adult asthma cohorts

Allergy. European Journal of Allergy and Clinical Immunology, Wiley 2019, Vol. 74, (2) : 406-411

Simpson, Andrew J.; Hekking, Pieter-Paul; Shaw, Dominick E.; et al.

Qualitative identification and characterisation of self-reported symptoms arising in humans during experimental exposure to cold air

International Journal of Circumpolar Health, Taylor & Francis 2019, Vol. 78, (1)

Sjöström, Rita; Söderström, Lars; Klockmo, Carolina; et al.

Sputum proteomic signature of gastro-oesophageal reflux in patients with severe asthma

Respiratory Medicine, Saunders Elsevier 2019, Vol. 150 : 66-73

Tariq, K.; Schofield, J. P. R.; Nicholas, B. L.; et al.

IL-17-high asthma with features of a psoriasis immunophenotype

Journal of Allergy and Clinical Immunology, Elsevier 2019, Vol. 144, (5) : 1198-1213

Östling, Jörgen; van Geest, Marleen; Schofield, James P. R.; et al.

Measures of adherence in patients with severe asthma prescribed systemic steroids in the U-BIOPRED cohort

European Respiratory Journal, European Respiratory Society 2018, Vol. 52

Alahmadi, Fahad; Simpson, Andrew; Gomez, Christina; et al.

Eosinophilic inflammation and lung function decline in a long-term follow-up of a large population-based asthma cohort

European Respiratory Journal, European Respiratory Society 2018, Vol. 52

Backman, Helena; Hedman, Linnea; Stridsman, Caroline; et al.

Severe asthma among adults: Prevalence and clinical characteristics

European Respiratory Journal, European Respiratory Society 2018, Vol. 52

Backman, Helena; Jansson, Sven-Arne; Stridsman, Caroline; et al.

Lipid phenotyping of lung epithelial lining fluid in healthy human volunteers

Metabolomics, Springer-Verlag New York 2018, Vol. 14, (10)

Brandsma, Joost; Goss, Victoria M.; Yang, Xian; et al.

Large-Scale Label-Free Quantitative Mapping of the Sputum Proteome

Journal of Proteome Research, American Chemical Society (ACS) 2018, Vol. 17, (6) : 2072-2091

Burg, Dominic; Schofield, James P. R.; Brandsma, Joost; et al.

Enhanced oxidative stress in smoking and ex-smoking severe asthma in the U-BIOPRED cohort

PLOS ONE, Public Library Science 2018, Vol. 13, (9)

Emma, Rosalia; Bansal, Aruna T.; Kolmert, Johan; et al.

Symptoms of moderate exercise in subzero temperatures - An experimental exposure study

European Respiratory Journal, European Respiratory Society 2018, Vol. 52

Eriksson, Linda; Schagatay, Filip; Sjöström, Rita; et al.

Energy expenditure in women and men with COPD

Clinical Nutrition ESPEN, Elsevier 2018, Vol. 28 : 171-178

Farooqi, Nighat; Carlsson, Maine; Håglin, Lena; et al.

Late Breaking Abstract - NORdic Database for aSThmA Research (NORDSTAR): Swedish and Finnish patients

European Respiratory Journal, European Respiratory Society 2018, Vol. 52

Geale, Kirk; Darabi, Hatef; Eklund, Oskar; et al.

Mass spectrometry profiling reveals altered plasma levels of monohydroxy fatty acids and related lipids in healthy humans after controlled exposure to biodiesel exhaust

Analytica Chimica Acta, Elsevier 2018, Vol. 1018 : 62-69

Gouveia-Figueira, Sandra C.; Karimpour, Masoumeh; Bosson, Jenny A.; et al.

Urban particulate matter stimulation of human dendritic cells enhances priming of naive CD8 T lymphocytes

Immunology, John Wiley & Sons 2018, Vol. 153, (4) : 502-512

Pfeffer, Paul E.; Ho, Tzer R.; Mann, Elizabeth H.; et al.

Nordic consensus statement on the systematic assessment and management of possible severe asthma in adults

European Clinical Respiratory Journal, Taylor & Francis 2018, Vol. 5

Porsbjerg, Celeste; Ulrik, Charlotte; Skjold, Tina; et al.

Topological data analysis (TDA) of U-BIOPRED paediatric peripheral blood gene expression identified asthma phenotypes characterised by alternative splicing of glucocorticoid receptor (GR) mRNA

European Respiratory Journal, European Respiratory Society 2018, Vol. 52

Schofield, James P. R.; Bigler, Jeanette; Boedigheimer, Michael; et al.

Sputum proteomics and airway cell transcripts of current and ex-smokers with severe asthma in U-BIOPRED: an exploratory analysis

European Respiratory Journal, EUROPEAN RESPIRATORY SOC JOURNALS LTD 2018, Vol. 51, (5)

Takahashi, Kentaro; Pavlidis, Stelios; Kwong, Francois Ng Kee; et al.

Periostin expression in the U-BIOPRED severe asthma bronchoscopy cohort

European Respiratory Journal, European Respiratory Society 2018, Vol. 52

Wilson, Susan Jane; Faruqi, Ali; Ward, Jonathan; et al.

Mass spectrometry profiling of oxylipins, endocannabinoids, and N-acylethanolamines in human lung lavage fluids reveals responsiveness of prostaglandin E2 and associated lipid metabolites to biodiesel exhaust exposure

Analytical and Bioanalytical Chemistry, SPRINGER HEIDELBERG 2017, Vol. 409, (11) : 2967-2980

Gouveia-Figueira, Sandra; Karimpour, Masoumeh; Bosson, Jenny A.; et al.

A transcriptome-driven analysis of epithelial brushings and bronchial biopsies to define asthma phenotypes in U-BIOPRED

American Journal of Respiratory and Critical Care Medicine, Vol. 194, (4) : 443-455

Kuo, Chih-Hsi Scott; Pavlidis, Stelios; Loza, Matthew; et al.

U-BIOPRED clinical adult asthma clusters linked to a subset of sputum omics

Journal of Allergy and Clinical Immunology, Vol. 139, (6) : 1797-1807

Lefaudeux, Diane; De Meulder, Bertrand; Loza, Matthew J; et al.

Characterization of secondary care for COPD in Sweden

European Clinical Respiratory Journal, Vol. 4

Sundh, Josefin; Janson, Christer; Johansson, Gunnar; et al.

Diesel exhaust augments allergen-induced lower airway inflammation in allergic individuals: a controlled human exposure study

Thorax, Vol. 71, (1) : 35-44

Carlsten, Chris; Blomberg, Anders; Pui, Mandy; et al.

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Research projects

1 January 2021 until 1 August 2028

COPD-HIIT