The course deals with the following subjects: Evolution, structure, dynamics, stability, folding and degradation of proteins. Relationships between structure and catalytic properties of enzymes as studied by site-directed mutagenesis. Translocation of proteins through membranes to various organelles. Membrane proteins, membrane transport and cellular signals, receptors. Cytoskeletal and contractile proteins. Immunoglobulins and other proteins of the immune system. DNA-binding proteins and viruses. Compulsory laboratory experiments and computer analysis are included in the course.