The course deals with nuclear diagnostic methods to detect the transportation ond transformation of chemical substancesof biological and other systems and provide training to control and optimize advanced nuclear diagnostic equipment. The course covers techniques for production of radionucleides, pharmacological requirements, measurement of uptakeand excretion, radioimmunoassay, gamma and positron camera, emission computerized tomography. Applied internaldosimtery and radiation protection are also included. The course includes compulsory laboratory work.