The course deals with different methods and highlights key safety aspects of radiotherapy and provides a good basis forwork as a medical physicist in a radiotherapy department. The course covers methods of internal and external radiotherapy, intensity modulation, as well as combination treatmentwith surgery, chemotherapy or hyperthermia. Different calculation algorithms for treatment planning, the impact ofinhomogeneities, simulation and control systems as well as radiation biological aspects of radiation therapy with modelsfor fractional treatment are studied. Radiation protection aspects for both patients and staff is also included. The courseincludes mandatory laboratory work.