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Image: Mattias Pettersson

Johan Trygg - Chemometrics Lab

Research group Advanced data analytics in life science is becoming a core element in modern data driven life science research. Our research focus on data from high-throughput molecular techniques to develop computational models to understand, simulate and predict behaviour of complex biological systems.

We focus on chemometrics as an overall framework that includes Design of experiments (DOE), multivariate data analysis, AI/machine learning and bioengineering tools, all this in collaboration with leading academic institutions and industry partners. Our vision is the prevention and efficient and affordable treatment of diseases worldwide. 

Chemometrics has been part of our DNA for more than 50 years when Svante Wold and Rolf Carlson led a movement that has transformed the pharmaceutical industry and modern drug development and manufacturing. In addition, we focus on “omics” disciplines, particularly phenotypic profiling such as metabolomics. Such methodologies have consistently demonstrated improved biological interpretation, identification of biomarkers and understanding mechanisms in disease, ranging from large scale biology studies to smaller clinical studies.  

Taking a systems biology approach, we target the integration of biological information across multiple phenotypic and “omics” platforms. Here, we are continuously developing multivariate tools and strategies to analyse and integrate omics data for quality control and enhancing the interpretation of biological data. This includes time series dynamic modeling of biological events and in silico cell painting of virtual fluorescent channels as part of our computational workflow. Here, domain expertise are critical elements for success. 

Head of research

Overview

Participating departments and units at Umeå University

Department of Chemistry

Research area

Infection biology
Associate Professor Elin Chorell - member of the scientific committee pictured here during a discussion session with one of the presenters.
The world metabolomics community gathers in the North

Metabolomics is a growing field within life science - 120 scientists from all over the world gathered in Umeå.

Platform for data analytics aims to reach national status

CASP receives SEK 1,8 million to support life scientists in data analytics.

Enabling 100-times faster fluorescent imaging of 3D cancer spheroids

Umeå researcher and the company Sartorius in Umeå combine deep learning with two imaging techniques.

Latest update: 2022-12-20