Anna Rosén

Associate professor and consultant in Clinical genetics,

PhD in Epidemiology and Public Health.

PI for the DIRECT-study.

Contact

anna.rosen@umu.se

+46 72 453 48 09

Works as

Physician at Department of Diagnostics and Intervention Section: Oncology

Byggnad 5B, plan 0, målpunkt P/PA, Regionalt Cancercentrum Norr, (RCC) Norrlands universitetssjukhus, 901 85 Umeå Umeå universitet, 901 85 Umeå

Physician at Department of Clinical Sciences Section: Professional Development

Norrlands universitetssjukhus, Umeå universitet, Klinisk vetenskap Umeå universitet, Klinisk vetenskap, 901 85 Umeå

I am leading the multicenter clinical RCT "Direct letters to relatives at risk of hereditary cancer –a randomised controlled trial of healthcare-assisted versus family-mediated risk disclosure at cancer genetics clinics in Sweden (DIRECT-study)" evaluating if the offer of sending direct letters to at-risk relatives is superior to standard care alone.

I have a fulltime employment as a senior consultant at Regional cancer center North. I received a FORTE grant as a junior researcher for the years 2019-2022 and during 2023-2028 I have a career support from the Swedish research council (Vetenskapsrådet). The DIRECT-project is also supported from Cancerfonden and the Regional agreement between Umeå University and Västerbotten County Council (Projektmedel centrala ALF samt basenhets-ALF).

“Choosing the main character”: healthcare professionals’ attitudes towards counselling patients about risk disclosure to relatives in the era of mainstream cancer genetic testing

Familial Cancer, Springer Netherlands 2026, Vol. 25, (1)

Öfverholm, Anna; Liljedahl, Matilda; Elmberger, Agnes; et al.

Direct letters to relatives at risk of hereditary cancer: a randomised trial on healthcare-assisted versus family-mediated risk disclosure

European Journal of Human Genetics, Springer Nature 2025, Vol. 33 : 1359-1367

Ehrencrona, Hans; Öfverholm, Anna; Hawranek, Carolina; et al.

Characterisation of heritable TP53-related cancer syndrome in Sweden: a nationwide study of genotype-phenotype correlations in 90 families

European Journal of Human Genetics, Springer Nature 2025, Vol. 33, (4) : 513-522

Omran, Meis; Liu, Yaxuan; Sun Zhang, Alexander; et al.

Genomic findings with familial implications: agenda setting in light of mainstreaming

Open Research Europe, F1000 Research Ltd 2025, Vol. 5

Phillips, Amicia; Van Steijvoort, Eva; Siermann, Maria; et al.

Cohort profile: the Northern Sweden health and disease study (NSHDS)

International Journal of Epidemiology, Oxford University Press 2025, Vol. 54, (1)

Späth, Florentin; Wennberg, Patrik; Johansson, Robert; et al.

Who has the responsibility to inform relatives at risk of hereditary cancer?: a population-based survey in Sweden

BMJ Open, BMJ Publishing Group Ltd 2024, Vol. 14, (11)

Grill, Kalle; Phillips, Amicia; Numan Hellquist, Barbro; et al.

How hereditary cancer risk disclosure to relatives is handled in practice: patient perspectives from a Swedish cancer genetics clinic

Patient Education and Counseling, Elsevier 2024, Vol. 126

Hawranek, Carolina; Rosén, Anna; Hajdarevic, Senada

Patients’ perceptions and practices of informing relatives: a qualitative study within a randomised trial on healthcare-assisted risk disclosure

European Journal of Human Genetics, Springer Nature 2024, Vol. 32 : 448-455

Nääs, Charlotta; von Salomé, Jenny; Rosén, Anna

Public attitudes challenge clinical practice on genetic risk disclosure in favour of healthcare-provided direct dissemination to relatives

European Journal of Human Genetics, Springer Nature 2024, Vol. 32, (1) : 6-7

Rosén, Anna; Krajc, Mateja; Ehrencrona, Hans; et al.

Diagnostic yield and clinical impact of germline sequencing in children with CNS and extracranial solid tumors: a nationwide, prospective Swedish study

The Lancet Regional Health: Europe, Elsevier 2024, Vol. 39

Tesi, Bianca; Robinson, Kristina Lagerstedt; Abel, Frida; et al.

The experience of receiving a letter from a cancer genetics clinic about risk for hereditary cancer

European Journal of Human Genetics, Springer Nature 2024, Vol. 32, (5) : 539-544

Öfverholm, Anna; Karlsson, Per; Rosén, Anna

Direct letters to relatives at risk of hereditary cancer: study protocol for a multi-center randomized controlled trial of healthcare-assisted versus family-mediated risk disclosure at Swedish cancer genetics clinics (DIRECT-study)

Trials, BioMed Central (BMC) 2023, Vol. 24, (1)

Hawranek, Carolina; Ehrencrona, Hans; Öfverholm, Anna; et al.

Extended genetic analysis and tumor characteristics in over 4600 women with suspected hereditary breast and ovarian cancer

BMC Cancer, BioMed Central (BMC) 2023, Vol. 23, (1)

Öfverholm, Anna; Törngren, Therese; Rosén, Anna; et al.

Cancer worry distribution and willingness to undergo colonoscopy at three levels of hypothetical cancer risk - a population-based survey in Sweden

Cancers, MDPI 2022, Vol. 14, (4)

Hawranek, Carolina; Maxon, Johan; Andersson, Andreas; et al.

Whole-Body MRI Surveillance: Baseline Findings in the Swedish Multicentre Hereditary TP53-Related Cancer Syndrome Study (SWEP53)

Cancers, MDPI 2022, Vol. 14, (2)

Omran, Meis; Tham, Emma; Brandberg, Yvonne; et al.

Oral glucose tolerance testing as a complement to fasting plasma glucose in screening for type 2 diabetes: population-based cross-sectional analyses of 146 000 health examinations in Västerbotten, Sweden

BMJ Open, BMJ Publishing Group Ltd 2022, Vol. 12, (6)

Rosén, Anna; Otten, Julia; Stomby, Andreas; et al.

Healthcare professionals' responsibility for informing relatives at risk of hereditary disease

Journal of Medical Ethics, BMJ Publishing Group Ltd 2021, Vol. 47, (12)

Grill, Kalle; Rosén, Anna

A focus group study of perceptions of genetic risk disclosure in members of the public in sweden: "I’ll phone the five closest ones, but what happens to the other ten?"

Journal of Personalized Medicine, MDPI 2021, Vol. 11, (11)

Hawranek, Carolina; Hajdarevic, Senada; Rosén, Anna

Public support for healthcare-mediated disclosure of hereditary cancer risk information: Results from a population-based survey in Sweden

Hereditary Cancer in Clinical Practice, Springer Nature 2020, Vol. 18

Andersson, Andreas; Hawranek, Carolina; Öfverholm, Anna; et al.

Cancer worry and willingness to undergo colonoscopy at different risk levels: results from a population-based survey in Sweden

European Journal of Human Genetics, Springer Nature 2020, Vol. 28 : 786-786

Hawranek, Carolina; Maxon, J.; Andersson, Andreas; et al.

Prophylactic Mastectomy: Postoperative Skin Flap Thickness Evaluated by MRT, Ultrasound and Clinical Examination

Annals of Surgical Oncology, Springer Nature 2020, Vol. 27 : 2221-2228

Wiberg, Rebecca; Andersson, Magnus N.; Svensson, Johan; et al.

The BRCA1 exon 13 duplication: clinical characteristics of 22 families in Northern Sweden

Familial Cancer, Springer 2019, Vol. 18, (1) : 37-42

Edwinsdotter Ardnor, Christina; Rosén, Anna; Ljuslinder, Ingrid; et al.

Novel variants in Nordic patients referred for genetic testing of telomere-related disorders

European Journal of Human Genetics, Nature Publishing Group 2018, Vol. 26, (6) : 858-867

Norberg, Anna; Rosén, Anna; Raaschou-Jensen, Klas; et al.

Role of HLA-DQ Genotyping in Celiac Disease

Journal of Pediatric Gastroenterology and Nutrition - JPGN, Vol. 62, (3) : E30-E31

Sandström, Olof; Rosén, Anna; Ivarsson, Anneli

High adherence to a gluten-free diet in adolescents with screening-detected celiac disease

Journal of Pediatric Gastroenterology and Nutrition - JPGN, Lippincott Williams & Wilkins 2015, Vol. 60, (1) : 54-59

Webb, Charlotta; Myléus, Anna; Norström, Fredrik; et al.

Celiac disease can be predicted by high levels of anti-tissue transglutaminase antibodies in population-based screening

Journal of Pediatric Gastroenterology and Nutrition - JPGN, Lippincott Williams & Wilkins 2015, Vol. 60, (6) : 787-791

Webb, Charlotta; Norström, Fredrik; Myléus, Anna; et al.

Internalizing the threat of risk: a qualitative study about adolescents' experience living with screening-detected celiac disease 5 years after diagnosis

Health and Quality of Life Outcomes, BioMed Central 2014, Vol. 12

Nordyke, Katrina; Rosén, Anna; Emmelin, Maria; et al.

Improving coeliac disease risk prediction by testing non-HLA variants additional to HLA variants

Gut, Vol. 63, (3) : 415-422

Romanos, Jihane; Rosén, Anna; Kumar, Vinod; et al.

Usefulness of symptoms to screen for celiac disease

Pediatrics, Vol. 133, (2) : 211-218

Rosén, Anna; Sandström, Olof; Carlsson, Annelie; et al.

Body mass index is not a reliable tool in predicting celiac disease in children

BMC Pediatrics, BioMed Central 2014, Vol. 14 : 165-

van der Pals, Maria; Myléus, Anna; Norström, Fredrik; et al.

Prevalence of childhood celiac disease and changes in infant feeding

Pediatrics, Vol. 131, (3) : e687-e694

Ivarsson, Anneli; Myléus, Anna; Norström, Fredrik; et al.

BMC Public Health, BioMed Central 2013, Vol. 13

Nordyke, Katrina; Norström, Fredrik; Lindholm, Lars; et al.

Transglutaminase IgA antibodies in a celiac disease mass screening and the role of HLA-DQ genotyping and endomysial antibodies in a sequential testing

Journal of Pediatric Gastroenterology and Nutrition - JPGN, Lippincott Williams & Wilkins 2013, Vol. 57, (4) : 472-476

Sandström, Olof; Rosén, Anna; Lagerqvist, Carina; et al.

Mass screening for celiac disease in 12-year-olds: Finding them and then what?

Umeå University medical dissertations, 1520

Rosén, Anna

Mass screening for celiac disease from the perspective of newly diagnosed adolescents and their parents: A mixed-method study

BMC Public Health, BioMed Central 2011, Vol. 11 : 822-

Rosén, Anna; Emmelin, Maria; Carlsson, Annelie; et al.

Balancing health benefits and social sacrifices: a qualitative study of how screening-detected celiac disease impacts adolescents' quality of life

BMC Pediatrics, BioMed Central 2011, Vol. 11 : 32-

Rosén, Anna; Ivarsson, Anneli; Nordyke, Katrina; et al.

The preventCD study design: towards new strategies for the prevention of coeliac disease

European Journal of Gastroenterology and Hepathology, Vol. 22, (12) : 1424-1430

Hogen Esch, Caroline Elisabeth; Rosén, Anna; Auricchio, Renata; et al.

Celiac disease revealed in 3% of Swedish 12-year-olds born during an epidemic

Journal of Pediatric Gastroenterology and Nutrition - JPGN, New York: Raven P 2009, Vol. 49, (2) : 170-176

Myléus, Anna; Ivarsson, Anneli; Webb, Charlotta; et al.

Reduced prevalence of childhood celiac disease: an effect of changes in infant feeding?

Ivarsson, Anneli; Myléus, Anna; Norström, Fredrik; et al.

Symptoms do not predict celiac disease in a mass screening of Swedish 12-year-olds

Rosén, Anna; Sandström, Olof; Carlsson, Annelie; et al.

View publications in DiVA

Research projects

2 September 2019 until 31 December 2028

The DIRECT-study - Disclosure of genetic risk to prevent cancer

Involved in teaching at the Medical programme, Master in biomedicine, Master in nursing, and internal courses for health care professionals.

Topics;

prevention
public health
screening
clinical genetics
hereditary cancer genetics
ethics and genetics
research methodology
qualitative research methodology
epidemiology