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Svenska
Kristina Lejon
Contact
E-mail
kristina.lejon@umu.se
Phone
+46 90 785 35 76
Works at
Affiliation
Professor at
Department of Clinical Microbiology
Units: Immunology
Location
By 6M, Plan 4, Universitetssjukhuset
Umeå universitet, 901 85 Umeå
Affiliation
Affiliated as professor at
Faculty of Medicine, Dean's Office
Location
Förvaltningshuset, Plan 7
Umeå universitet, 901 87 Umeå
Publications
Publications
Research
Research
2021
Anti-CD74 IgA autoantibodies in radiographic axial spondyloarthritis: a longitudinal Swedish study
Rheumatology
, Oxford University Press 2021, Vol. 60, (9) : 4085-4093
Do, Lan; Granåsen, Gabriel; Hellman, Urban; et al.
2021
DECREASED LEVELS OF T FOLLICULAR HELPER (CD4+CXCR5+) CELLS AND CD27+CD38+ AND CD27+CD38- B CELLS IN ANKYLOSING SPONDYLITIS PATIENTS CORRELATE WITH MARKER OF INFLAMMATION
Annals of the Rheumatic Diseases
, BMJ Publishing Group Ltd 2021, Vol. 80, (Suppl 1) : 13-14
Forsblad-D'elia, H.; Hellman, Urban; Kumar, A.; et al.
2021
Dysregulated microRNA expression in rheumatoid arthritis families-a comparison between rheumatoid arthritis patients, their first-degree relatives, and healthy controls
Clinical Rheumatology
, Springer 2021, Vol. 40, (6) : 2387-2394
Renman, Emma; Brink, Mikael; Ärlestig, Lisbeth; et al.
2021
Atherosclerosis in rheumatoid arthritis: associations between anti-cytomegalovirus IgG antibodies, CD4+CD28null T-cells, CD8+CD28null T-cells and intima-media thickness
Clinical and Experimental Rheumatology
, Vol. 39, (3) : 578-586
Wahlin, Bengt; Fasth, Andreas; Karp, Kjell; et al.
2020
Protein profiling in individuals before onset of anca-associated vasculitis
Annals of the Rheumatic Diseases
, BMJ Publishing Group Ltd 2020, Vol. 79 : 372-372
Berglin, Ewa; Esberg, Anders; Dahlqvist, J.; et al.
2020
Increased Proportion of TH17, TH22 and TC17 Cells and the Correlation to IL-22 and Clinical Parameters in Patients with Ankylosing Spondylitis from Northern Sweden
Arthritis & Rheumatology
, John Wiley & Sons 2020, Vol. 72
Lejon, Kristina; Hellman, Urban; Do, Lan; et al.
2019
Protein profiling and network enrichment analysis in individuals before and after the onset of rheumatoid arthritis
Arthritis Research & Therapy
, BioMed Central 2019, Vol. 21, (1)
Brink, Mikael; Lundquist, Anders; Alexeyenko, Andrey; et al.
2019
Protein Profiling and Network Enrichment Analysis in Individuals Before and After the Onset of Rheumatoid Arthritis
Arthritis & Rheumatology
, John Wiley & Sons 2019, Vol. 71
Brink, Mikael; Lundquist, Anders; Alexeyenko, Andrey; et al.
2019
Innate lymphoid cells are present in gingivitis and periodontitis
Journal of Periodontology
, Wiley-Blackwell 2019, Vol. 90, (2) : 200-207
Kindstedt, Elin; Holm, Cecilia Koskinen; Palmqvist, Py; et al.
2017
Elevated Systemic Glutamic Acid Level in the Non-Obese Diabetic Mouse is Idd Linked and Induces Beta Cell Apoptosis
Immunology
, Vol. 150, (2) : 162-171
Banday, Viqar Showkat; Lejon, Kristina
2017
Contribution of both B cell intrinsic alterations as well as non-hematopoietic derived factors in the enhanced immune response of the NOD mouse
Scandinavian Journal of Immunology
, WILEY 2017, Vol. 86, (4) : 252-252
Banday, Viqar Showkat; Thyagarajan, Radha; Lejon, Kristina
2017
Contribution of both B-cell intrinsic alterations as well as non-hematopoietic-derived factors in the enhanced immune response of the NOD mouse
Autoimmunity
, TAYLOR & FRANCIS LTD 2017, Vol. 50, (6) : 363-369
Banday, Viqar Showkat; Thyagarajan, Radha; Lejon, Kristina
2017
Immunsystemets fina balansgång
Sticket : informationsblad från Barndiabetesfonden
, Linköping: Bandiabetesfonden 2017, Vol. 24, (3) : 4-4
Lejon, Kristina
2017
Cd8+cd28- t-lymphocytes are associated with subclinical atherosclerosis in patients with rheumatoid arthritis
Annals of the Rheumatic Diseases
, BMJ PUBLISHING GROUP 2017, Vol. 76 : 250-250
Wahlin, Bengt; Fasth, A. E.; Karp, Kjell; et al.
2016
Increased expression of TACI on NOD B cells results in germinal centre reaction anomalies, enhanced plasma cell differentiation and immunoglobulin production
Immunology
, Vol. 149, (3) : 297-305
Banday, Viqar Showkat; Thyagarajan, Radha; Sundström, Mia; et al.
2016
Cytotoxic immune responses in the lungs correlate to disease severity in patients with hantavirus infection
European Journal of Clinical Microbiology and Infectious Diseases
, Vol. 35, (4) : 713-721
Rasmuson, Johan; Pourazar, Jamshid; Mohamed, Nahla; et al.
2015
Lack of non-hematopoietic SIRPα signaling disturbs the splenic marginal zone architecture resulting in accumulation and displacement of marginal zone B cells
Biochemical and Biophysical Research Communications - BBRC
, Vol. 460, (3) : 645-650
Kolan, Shrikant; Boman, Andreas; Matozaki, Takashi; et al.
2015
Non-Hematopoietic and Hematopoietic SIRPα Signaling Differently Regulates Murine B Cell Maturation in Bone Marrow and Spleen
PLoS One
, plos one 2015, Vol. 10, (7)
Kolan, Shrikant; Lejon, Kristina; Koskinen Holm, Cecilia; et al.
2015
Contribution of autoallergy to the pathogenesis in the NOD mice
Autoimmunity
, Vol. 48, (5) : 298-304
Thyagarajan, Radha; Banday, Viqar; Ding, Zhoujie; et al.
2014
B Regulatory Cells are Functionally Impaired in Patients with Rheumatoid Arthritis and in Their First-Degree Relatives Compared with Controls
Scandinavian Journal of Immunology
, Vol. 79, (6) : 450-450
Brink, Mikael; Ärlestig, Lisbeth; Rantapää-Dahlqvist, Solbritt; et al.
2014
B Cells and IgE in Type 1 Diabetes
Scandinavian Journal of Immunology
, Vol. 79, (6) : 452-452
Thyagarajan, Radha; Lejon, Kristina
2013
B-Regulatory-, CD19(+)CD20(+) CD24(high)CD38(high) -Cells Are Functionally Impaired In Patients With Rheumatoid Arthritis and Healthy First Degree Relatives Compared With Controls
Arthritis and Rheumatism
, Wiley-Blackwell 2013, Vol. 65, (Special issue, Supplement 10) : S393-S394, Meeting Abstract: 917
Brink, Mikael; Lejon, Kristina; Ärlestig, Lisbeth; et al.
2013
Två bitar i det stora pusslet
Sticket
, Linköping: Barndiabetesfonden 2013, Vol. 2 : 4-
Lejon, Kristina
2013
Välkomna till 2013 års Forskningens dag!
Cancerforskning på nya vägar: en bok från Forskningens dag 2013, Medicinska fakulteten vid Umeå universitet
, Umeå: Umeå universitet 2013 : 7-14
Stigbrand, Torgny; Lejon, Kristina
2012
Altered metabolic signature in Pre-Diabetic NOD Mice
PLOS ONE
, Public Library of Science 2012, Vol. 7, (4) : e35445-
Madsen, Rasmus; Banday, Viqar Showkat; Moritz, Thomas; et al.
2010
Up-regulation of cytokines and chemokines predates the onset of rheumatoid arthritis
Arthritis and Rheumatism
, Vol. 62, (2) : 383-391
Kokkonen, Heidi; Söderström, Ingegerd; Rocklöv, Joacim; et al.
2010
The prolonged and enhanced immune response in the non-obese diabetic mouse is dependent on genes in the Idd1/24, Idd12 and Idd18 regions
Journal of Autoimmunity
, Vol. 35, (4) : 375-382
Sundström, Mia; Lejon, Kristina
2009
Enhanced capture of extramembranous IgM and IgG on B cells in the NOD mouse: implications for immune complex trapping
International Immunology
, Vol. 21, (5) : 533-541
Ekici, Rifat; Sundström, Mia; Thay, Bernard; et al.
2007
The NOD allele of the Idd5 locus on chromosome 1 mediates a non-cell-autonomous defect in negative selection of T cells.
Journal of Autoimmunity
, Vol. 28, (4) : 216-223
Motta, Vinicius; Lejon, Kristina; Holmberg, Dan
2007
Idd-linked genetic regulation of TACIhigh expressing B cells in NOD mice
Journal of Autoimmunity
, Vol. 29, (2-3) : 116-124
Sundström, Mia; Lejon, Kristina
2006
EDAR mutation in autosomal dominant hypohidrotic ectodermal dysplasia in two Swedish families
BMC Medical Genetics
, BioMed Central 2006, Vol. 7 : 80-
Lind, Lisbet K; Stecksén-Blicks, Christina; Lejon, Kristina; et al.
2005
Expression of the NK-1 receptor on islet cells and invading immune cells in the non-obese diabetic mouse
Journal of Autoimmunity
, Elsevier 2005, Vol. 24, (4) : 269-279
Persson-Sjögren, Solveig; Lejon, Kristina; Holmberg, Dan; et al.
2004
Kompetens ingen efterfrågar
Kemivärlden Biotech
, Svenska Kemistsamfundet 2004, Vol. 10, (21)
Lejon, Kristina
2003
Diabetes protection and restoration of thymocyte apoptosis in NOD Idd6 congenic strains
Diabetes
, American Diabetes Association 2003, Vol. 52, (7) : 1677-1682
Bergman, Marie-Louise; Duarte, Nadia; Campino, Susana; et al.
2002
The CD8alpha
+
dendritic cell is responsible for inducing peripheral self-tolerance to tissue-associated antigens.
Journal of Experimental Medicine
, The Rockefeller University Press 2002, Vol. 196, (8) : 1099-1104
Belz, Gabrielle T; Behrens, Georg M N; Smith, Chris M; et al.
2001
CTLA-4-/- mice display T cell-apoptosis resistance resembling that ascribed to autoimmune-prone non-obese diabetic (NOD) mice
Journal of Autoimmunity
, Elsevier 2001, Vol. 16, (2) : 105-113
Bergman, Marie-Louise; Cilio, Corrado M; Penha-Gonçalves, Carlos; et al.
2001
Low rate of proliferation in immature thymocytes of the non-obese diabetic mouse maps to the Idd6 diabetes susceptibility region
Diabetologia
, Springer 2001, Vol. 44, (8) : 1054-1061
Bergman, Marie-Louise; Penha-Gonçalves, Carlos; Lejon, Kristina; et al.
2001
CD4
+
CD25
+
T cells facilitate the induction of T cell anergy
Journal of Immunology
, Rockville Pike, Bethesda, MD: The American Association of Immunologists, Inc. 2001, Vol. 167, (8) : 4271-4275
Ermann, Joerg; Szanya, Veronika; Ford, Gregory S.; et al.
2001
The identification and validation of common disease genes: relevance to the drug development process.
Current opinion in molecular therapeutics (Print)
, Vol. 3, (6) : 533-537
Holmberg, Mats; Lejon, Kristina
1999
Isolation of self antigen-reactive cells from inflamed islets of nonobese diabetic mice using CD4
high
expression as a marker
Journal of Immunology
, The American Association of Immunologists 1999, Vol. 163, (10) : 5708-5714
Lejon, Kristina; Garrison Fathman, C.
1998
How murine genetics can help to identify susceptibility genes in human disease
Diabetes Metabolism Reviews
, John Wiley & Sons 1998, Vol. 14, (2) : 190-191
Cilio, Corrado M.; Lejon, Kristina; Penha-Goncalves, Carlos; et al.
1998
Diabetes induction in C57BL/6 mice reconstituted with lymphocytes of nonobese diabetic C57BL/6 mouse embryo aggregation chimeras
Scandinavian Journal of Immunology
, Wiley-Blackwell 1998, Vol. 48, (6) : 571-576
Colucci, Francesco; Bergman, Marie-Louise; Lejon, Kristina; et al.
1996
Programmed cell death in the pathogenesis of murine IDDM: resistance to apoptosis induced in lymphocytes by cyclophosphamide
Journal of Autoimmunity
, Elsevier 1996, Vol. 9, (2) : 271-276
Colucci, Francesco; Cilio, Corrado M.; Lejon, Kristina; et al.
1996
Induction of diabetes in NOD‹–›C57BL/6 embryo aggregation chimeras by cyclophosphamide through preferential depletion of C57BL/6 lymphocytes
Journal of Autoimmunity
, Elsevier 1996, Vol. 9, (4) : 493-499
Colucci, Francesco; Lejon, Kristina; Cilio, Corrado M.; et al.
1996
Cellular and genetic components in the development of IDDM in NOD mice.
Umeå University medical dissertations
, 464
Lejon, Kristina
1996
Establishment and characterization of RAG-2 deficient non-obese diabetic mice
Scandinavian Journal of Immunology
, John Wiley & Sons 1996, Vol. 43, (5) : 525-530
Söderström, Ingegerd; Bergman, Marie-Louise; Colucci, F.; et al.
1995
Specific destruction of islet transplants in NOD‹–›C57BL/6 and NOD‹–›C3H/Tif embryo aggregation chimeras irrespective of allelic differences in beta-cell antigens
Journal of Autoimmunity
, Elsevier 1995, Vol. 8, (3) : 347-356
Leijon, Kristina; Hillörn, Valter; Bergqvist, Ingela; et al.
1995
Type 1 diabetes and the control of dexamethazone-induced apoptosis in mice maps to the same region on chromosome 6
Genomics
, Elsevier 1995, Vol. 28, (3) : 398-404
Penha-Gonçalves, Carlos; Leijon, Kristina; Persson, Linda; et al.
1994
Non-obese diabetic (NOD) mice display enhanced immune responses and prolonged survival of lymphoid cells
International Immunology
, Oxford: Oxford University Press 1994, Vol. 6, (2) : 339-345
Leijon, Kristina; Hammarström, Barbro; Holmberg, Dan
1993
Analysis of V
H
gene utilisation in the non-obese diabetic mouse
Autoimmunity
, Harwood Academic 1993, Vol. 15, (1) : 11-18
Leijon, Kristina; Freitas, A; Holmberg, Dan
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