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Gauti Jóhannesson

Wallenberg Molecular Medicine Fellows: Neuroscience

Glaucoma

Glaucoma is a chronic, progressive disease that results in damage to the optic nerve and vision loss. Glaucoma is a common disease affecting 2% of the population above 40 years of age and it causes great suffering and distress throughout the world as it is the main cause of irreversible blindness worldwide. Although vastly prevalent, there is no cure yet available for glaucoma and the only treatment option is lowering IOP to slow the neurodegenerative progress of the disease.

Our group focuses on understanding the pathophysiology of glaucoma through advanced imaging technology. In particular, our work uses advanced magnetic resonance imaging (MRI) with and without simultaneous positron emission tomography (PET-MRI) in order to investigate the role of blood flow and metabolic changes in glaucoma. We hope that this research will help us identify new glaucoma biomarkers and provide us with better understanding of the pathophysiology, ultimately leading to the development of new treatment options in the future.

Gauti Jóhannesson