Umeå University is one of Sweden’s largest higher education institutions with over 37,000 students and about 4,700 employees. The University offers a diversity of high-quality education and world-leading research in several fields. Notably, the groundbreaking discovery of the CRISPR-Cas9 gene-editing tool, which was awarded the Nobel Prize in Chemistry, was made here. At Umeå University, everything is close. Our cohesive campuses make it easy to meet, work together and exchange knowledge, which promotes a dynamic and open culture.
The ongoing societal transformation and large green investments in northern Sweden create enormous opportunities and complex challenges. For Umeå University, conducting research about – and in the middle of – a society in transition is key. We also take pride in delivering education to enable regions to expand quickly and sustainably. In fact, the future is made here.
The Department of Molecular Biology seeks a postdoctor in molecular medicine. The appointment is a full-time, temporary position for two years in accordance with the terms of contract for fixed-term employment as a postdoctoral researcher. The position is expected to start 1 May. 2026, or upon agreement. Last day to apply is 18 February, 2026.
Description of the project
Hypoxia inhibits appetite, yet the underlying mechanisms remain poorly understood. Our recent findings implicate GPCR signaling as a potential regulator of hypoxia-induced suppression of food intake. This project seeks to define how GPCR signaling contributes to anorexic responses under hypoxic conditions, using C. elegans as the primary model. By combining genetic, physiological, and behavioral approaches, the study will dissect how hypoxic cues are detected and translated into changes in feeding behavior, providing mechanistic insight into how oxygen availability modulates appetite.
Work responsibilities
The candidate is expected to independently plan and execute experimental studies, including the generation of mutant and transgenic strains, the establishment and optimization of behavioral assays under controlled oxygen conditions, image‑based analyses, and quantitative data processing and interpretation. The role also includes active participation in manuscript preparation and the supervision of students.
Eligibility
The candidate shall have a PhD, or a foreign qualification deemed to be the equivalent of a doctorate in biology, genetics, biochemistry or a closely related field. This eligibility requirement must be met no later than the time at which the appointment decision is made. The ideal candidate shall have demonstrated expertise in genetics, neurobiology, biochemistry, or relevant areas. Priority will be given to highly motivated applicants who have work with C. elegans.
As an employee with us, you contribute to fostering an inclusive culture and a positive work environment. This involves communicating effectively across differences, demonstrating a collaborative spirit and the ability to work well with others. You maintain openness and a welcoming attitude, showing respect, compassion, and empathy. You engage with and support colleagues from diverse backgrounds and perspectives and promote a healthy work-life balance for both you and others.
Additional useful qualifications
This project involves extensive genome editing in C. elegans. Prior experience with microinjection is therefore highly desirable.
Application
The application must include:
· A brief description of your research interests and a statement describing why you are interested in the position.
· CV
· List of publications
· Degree certificate from doctoral studies and other relevant degrees
· Contact details of two reference persons
The application must be written in Swedish or English. The application must be made via our e-recruitment system Varbi and be received latest 18 February 2026.
More about us
More information about the group's research can be found on our website Changchun Chen lab
Umeå University wants to offer an equal environment where open dialogue between people with different backgrounds and perspectives lay the foundation for learning, creativity and development. We welcome people with different backgrounds and experiences to apply for the current employment.
We kindly decline offers of recruitment and advertising help.
