Integrated Biomedical Sciences Seminar: Conor O'Byrne

Slowly but surely wins the race: trade-offs in the evolution of Listeria monocytogenes

Talare: Conor O'Byrne, University of Galway, Ireland

Conor O'Byrne lab webbplats

Värd: Jörgen Johansson, Institutionen för molekylärbiologi

Om föreläsningen:

Listeria monocytogenes is facultative intracellular pathogen that displays remarkable adaptability to harsh environmental conditions, including low pH and low temperatures and low water activity. In part this resistance to environmental stress stems from the SigB-regulated general stress response (GSR). The SigB regulon comprises around 300 genes whose functions contribute to critical homeostatic and protective functions. While the GSR plays a pivotal role in surviving under harsh conditions we have found that there is a significant cost to deploying it and in several conditions we see the emergence of mutations that negatively affect the GSR. In this seminar I will present these data and discuss the implications for the evolution of this pathogen.

Hitta hit: Föreläsningssalen 5B P6 Stora hörsalen ligger i sjukhusets lokaler. Mazemap-länken för hörsalen är https://link.mazemap.com/rGiySLeg

Integrated Biomedical Science Seminars är en bred, öppen seminarieserie inom life science.