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English
Lotta Edvinsson
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lotta.edvinsson@umu.se
Verksam som
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Övrig/annan befattning
vid
Institutionen för diagnostik och intervention
Plats
5A, Målpunkt H62, Norrlands universitetssjukhus
Umeå universitet, 901 85 Umeå
Publikationer
Publikationer
2017
Exploring non-covalent interactions between drug-like molecules and the protein acetylcholinesterase
Umeå: Umeå universitet 2017
Berg, Lotta
2016
Structure of a prereaction complex between the nerve agent sarin, its biological target acetylcholinesterase, and the antidote HI-6
Proceedings of the National Academy of Sciences of the United States of America
, Vol. 113, (20) : 5514-5519
Allgardsson, Anders; Berg, Lotta; Akfur, Christine; et al.
2016
The Nature of Activated Non-classical Hydrogen Bonds: A Case Study on Acetylcholinesterase-Ligand Complexes
Chemistry - A European Journal
, Wiley-VCH Verlagsgesellschaft 2016, Vol. 22, (8) : 2672-2681
Berg, Lotta; Mishra, Brijesh Kumar; Andersson, C. David; et al.
2015
Benefits of statistical molecular design, covariance analysis, and reference models in QSAR: a case study on acetylcholinesterase
Journal of Computer-Aided Molecular Design
, Vol. 29, (3) : 199-215
Andersson, C. David; Hillgren, J. Mikael; Lindgren, Cecilia; et al.
2015
Hydroxyethylene isosteres introduced in type II collagen fragments substantially alter the structure and dynamics of class II MHC A(q)/glycopeptide complexes
Organic and biomolecular chemistry
, Vol. 13, (22) : 6203-6216
Lindgren, Cecilia; Andersson, Ida E.; Berg, Lotta; et al.
2013
Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors
Journal of Medicinal Chemistry
, American Chemical Society (ACS) 2013, Vol. 56, (19) : 7615-7624
Andersson, C. David; Forsgren, Nina; Akfur, Christine; et al.
2012
Similar but Different: Thermodynamic and Structural Characterization of a Pair of Enantiomers Binding to Acetylcholinesterase
Angewandte Chemie International Edition
, Vol. 51, (51) : 12716-12720
Berg, Lotta; Niemiec, Moritz S.; Qian, Weixing; et al.
2011
Targeting Acetylcholinesterase: Identification of Chemical Leads by High Throughput Screening, Structure Determination and Molecular Modeling
PLOS ONE
, San Francisco: Public Library of Science 2011, Vol. 6, (11)
Berg, Lotta; Andersson, C. David; Artursson, Elisabet; et al.
2011
Postprocessing of docked protein-ligand complexes using implicit solvation models
Journal of chemical information and modeling
, Vol. 51, (2) : 267-282
Lindström, Anton; Edvinsson, Lotta; Johansson, Andreas; et al.
2010
Oxazole-modified glycopeptides that target arthritis-associated class II MHC A
q
and DR4 proteins
Organic and biomolecular chemistry
, RSC Publishing 2010, Vol. 8, (13) : 2931-2940
Andersson, Ida E.; Batsalova, Tsvetelina; Dzhambazov, Balik; et al.
Design of Reactive Drugs: Structure and Mechanism of Novel Nerve Agent Antidotes
Lindgren, Cecilia; Forsgren, Nina; Akfur, Christine; et al.
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