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Umeå universitet
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Huvudmenyn dold.
Personalbild Martin Cohn

Martin Cohn

Kontakt

E-post
martin.cohn@umu.se
Telefon
090-786 56 10

Verksam som

Anknytning
Universitetslektor vid Institutionen för molekylärbiologi
Plats
6K och 6L, Sjukhusområdet Umeå universitet, 901 87 Umeå
PP2A licenses the FANCD2/FANCI complex for chromosome loading
Cell Reports, Cell Press 2024, Vol. 43, (11)
Yang, Di; Bai, Fengxiang; Lopez Martinez, David; et al.
Phosphorylation by ATR triggers FANCD2 chromatin loading and activates the Fanconi anemia pathway
Cell Reports, Cell Press 2023, Vol. 42, (7)
Kupculak, Marian; Bai, Fengxiang; Luo, Qiang; et al.
Purification of DNA repair protein complexes from mammalian cells
STAR protocols, Elsevier 2021, Vol. 2, (1)
Liang, Chih-Chao; Cohn, Martin A.
WRNIP1 is recruited to DNA interstrand crosslinks and promotes repair
Cell Reports, Elsevier 2020, Vol. 32, (7)
Socha, Anna; Yang, Di; Bulsiewicz, Alicja; et al.
UBR5 interacts with the replication fork and protects DNA replication from DNA polymerase η toxicity.
Nucleic Acids Research, Oxford University Press 2019, Vol. 47, (21) : 11268-11283
Cipolla, Lina; Bertoletti, Federica; Maffia, Antonio; et al.
Phosphorylation of FANCD2 inhibits the FANCD2/FANCI complex and suppresses the Fanconi anemia pathway in the absence of DNA damage
Cell Reports, Elsevier 2019, Vol. 27, (10) : 2990-3005.e5.
Lopez-Martinez, David; Kupculak, Marian; Yang, Di; et al.
Identification of UHRF2 as a novel DNA interstrand crosslink sensor protein
PLOS Genetics, Public Library of Science (PLoS) 2018, Vol. 14, (10)
Motnenko, Anna; Liang, Chih-Chao; Yang, Di; et al.
Phosphorylation regulates human polη stability and damage bypass throughout the cell cycle
Nucleic Acids Research, Oxford University Press 2017, Vol. 45, (16) : 9441-9454
Bertoletti, Federica; Cea, Valentina; Liang, Chih-Chao; et al.
The FANCD2–FANCI complex is recruited to DNA interstrand crosslinks before monoubiquitination of FANCD2
Nature Communications, Nature Publishing Group 2016, Vol. 7, (1)
Liang, Chih-Chao; Li, Zhuolun; Lopez-Martinez, David; et al.
Cellular response to DNA interstrand crosslinks: the Fanconi anemia pathway
Cellular and Molecular Life Sciences (CMLS), Springer 2016, Vol. 73, (16) : 3097-3114
Lopez-Martinez, David; Liang, Chih-Chao; Cohn, Martin A.
UHRF1 is a sensor for DNA interstrand crosslinks
Oncotarget, Impact Journals 2015, Vol. 7, (1) : 3-4
Liang, Chih-Chao; Cohn, Martin A.
UHRF1 Is a sensor for DNA interstrand crosslinks and recruits FANCD2 to initiate the Fanconi Anemia pathway
Cell Reports, Elsevier 2015, Vol. 10, (12) : 1947-1957
Liang, Chih-Chao; Zhan, Bao; Yoshikawa, Yasunaga; et al.
The Fanconi anemia pathway maintains genome stability by coordinating replication and transcription
Molecular Cell, Elsevier 2015, Vol. 60, (3) : 351-361
Schwab, Rebekka A.; Nieminuszczy, Jadwiga; Shah, Fenil; et al.
DNA interstrand cross-link repair requires replication-fork convergence
Nature Structural & Molecular Biology, Nature Publishing Group 2015, Vol. 22 : 242-247
Zhang, Jieqiong; Dewar, James M.; Budzowska, Magda; et al.
The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation
Journal of Biological Chemistry, Elsevier 2012, Vol. 287, (35) : 29429-29441
Moretti, Julien; Chastagner, Patricia; Liang, Chih-Chao; et al.
WDR20 regulates activity of the USP12·UAF1 deubiquitinating enzyme complex
Journal of Biological Chemistry, Elsevier 2010, Vol. 285, (15) : 11252-11257
Kee, Younghoon; Yang, Kailin; Cohn, Martin A.; et al.
Human ELG1 regulates the level of ubiquitinated proliferating cell nuclear antigen (PCNA) through its interactions with PCNA and USP1
Journal of Biological Chemistry, Elsevier 2010, Vol. 285, (14) : 10362-10369
Lee, Kyoo-young; Yang, Kailin; Cohn, Martin A.; et al.
UAF1 is a subunit of multiple deubiquitinating enzyme complexes
Journal of Biological Chemistry, Elsevier 2009, Vol. 284, (8) : 5343-5351
Cohn, Martin A.; Kee, Younghoon; Haas, Wilhelm; et al.
Chromatin recruitment of DNA repair proteins: lessons from the fanconi anemia and double-strand break repair pathways.
Molecular Cell, Elsevier 2008, Vol. 32, (3) : 306-312
Cohn, Martin A.; D’Andrea, Alan D.
A UAF1-containing multisubunit protein complex regulates the Fanconi anemia pathway
Molecular Cell, Elsevier 2007, Vol. 28, (5) : 786-797
Cohn, Martin A.; Kowal, Przemyslaw; Yang, Kailin; et al.
Regulation of monoubiquitinated PCNA by DUB autocleavage
Nature Cell Biology, Nature Publishing Group 2006, Vol. 8, (4) : 339-347
Huang, Tony T.; Nijman, Sebastian M.B.; Mirchandani, Kanchan D.; et al.
A human DNA polymerase eta complex containing Rad18, Rad6 and Rev1: proteomic analysis and targeting of the complex to the chromatin-bound fraction of cells undergoing replication fork arrest
Genes to Cells, Wiley-Blackwell 2006, Vol. 11, (7) : 731-744
Yuasa, Mayumi S.; Masutani, Chikahide; Hirano, Akihiko; et al.
Large-scale characterization of HeLa cell nuclear phosphoproteins
Proceedings of the National Academy of Sciences of the United States of America, Proceedings of the National Academy of Sciences (PNAS) 2004, Vol. 101, (33) : 12130-12135
Beausoleil, Sean A.; Jedrychowski, Mark; Schwartz, Daniel; et al.
The ability of Fos family members to produce phenotypic changes in epithelioid cells is not directly linked to their transactivation potentials
Oncogene, Nature Publishing Group 2002, Vol. 21 : 4843-4848
Andersen, Henriette; Mahmood, Shaukat; Tkach, Vadim; et al.
Possible co-regulation of genes associated with enhanced progression of mammary adenocarcinomas
Immunology Letters, Elsevier 2002, Vol. 82, (1-2) : 111-121
Neumark, E.; Cohn, Martin A.; Lukanidin, E.; et al.
Characterization of Sp1, AP-1, CBF and KRC binding sites and minisatellite DNA as functional elements of the metastasis-associated mts1/S100A4 gene intronic enhancer
Nucleic Acids Research, Oxford University Press 2001, Vol. 29, (16) : 3335-3346
Cohn, Martin A.; Hjelmsø, Iben; Wu, Lai-Chu; et al.
Tumor suppressor p53 protein is a new target for the metastasis-associated Mts1/S100A4 protein: functional consequences of their interaction
Journal of Biological Chemistry, Elsevier 2001, Vol. 276, (25) : 22699-22708
Grigorian, Mariam; Andresen, Susanne; Tulchinsky, Eugene; et al.
The κB and V(D)J recombination signal sequence binding protein KRC regulates transcription of the mouse metastasis-associated gene S100A4/mts1
Journal of Biological Chemistry, Elsevier 2000, Vol. 275, (2) : 913-920
Hjelmsoe, Iben; Allen, Carl E.; Cohn, Martin A.; et al.
Intermolecular cross-talk in tumor metastasis
NATO ASI Book series. Series A. Life sciences, 311
Skouteris, George G.; Nicolson, Garth L.
The differentiation antigen Ly-6E.1 is expressed in mouse metastatic tumor cell lines
FEBS Letters, John Wiley & Sons 1997, Vol. 403, (2) : 181-185
Cohn, Martin A.; Kramerov, Dmitri; Hulgaard, Egil F.; et al.
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Forskargrupper

Forskningsledare
Martin Cohns forskargrupp