Mingde Wang

Vetenskaplig meritering: Docent

Kontakt

mingde.wang@umu.se

090-785 33 23

Verksam vid

Anknuten som övrig/annan befattning till Institutionen för klinisk vetenskap Enhet: Obstetrik och gynekologi

by 5B, 5 tr, NUS Umeå universitet, Kinisk vetenskap, Obstetrik och gynekologi, 90185 Umeå

Publikationer Publikationer

GABA-A receptor modulating steroids in acute and chronic stress; relevance for cognition and dementia?

Neurobiology of stress, Elsevier 2020, Vol. 12

Bengtsson, Sara; Bäckström, Torbjörn; Brinton, R.; et al.

The author's reply: Blood allopregnanolone levels in women with polycystic ovary syndrome

Clinical Endocrinology, Vol. 85, (1) : 152-154

Turkmen, Sahruh; Bixo, Marie; Hedström, Helena; et al.

Women with polycystic ovary syndrome have elevated serum concentrations of and altered GABA _A receptor sensitivity to allopregnanolone

Clinical Endocrinology, John Wiley & Sons 2015, Vol. 83, (5) : 643-650

Hedström, Helena; Bäckström, Torbjörn; Bixo, Marie; et al.

Brief but Chronic Increase in Allopregnanolone Cause Accelerated ADPathology Differently in Two Mouse Models

Current Alzheimer Research, Bentham Science Publishers 2013, Vol. 10, (1) : 38-47

Bengtsson, Sara; Johansson, Maja; Bäckström, Torbjörn; et al.

Brief but Chronic Increase in Allopregnanolone Cause Accelerated AD Pathology Differently in Two Mouse Models

Current Alzheimer Research, Bentham Science Publishers 2013, Vol. 10, (1) : 38-47

Bengtsson, Sara K.; Johansson, Maja; Bäckström, Torbjörn; et al.

Neurosteroids and brain aging

Minerva Ginecologica, Edizioni Minerva Medica 2013, Vol. 65, (6) : 587-605

Wang, Mingde

Chronic Allopregnanolone Treatment Accelerates Alzheimer's Disease Development in A beta PP(Swe)PSEN1(Delta E9) Mice

Journal of Alzheimer's Disease, Vol. 31, (1) : 71-84

Bengtsson, Sara K.; Johansson, Maja; Bäckström, Torbjörn; et al.

Neurosteroids and GABA-A receptor function

Frontiers in Neuroendocrine science, Vol. 2, (44) : 1-23

Wang, Mingde

Agonist function of the recombinant alpha 4 beta 3 delta GABAA receptor is dependent on the human and rat variants of the alpha 4-subunit

Clinical and experimental pharmacology & physiology, Blackwell Publishing 2010, Vol. 37, (7) : 662-669

Wang, Ming-De; Rahman, Mozibur; Johansson, Inga-Maj; et al.

The effect of the neuroactive steroid 5β-pregnane-3β, 20(R)-diol on the time course of GABA evoked currents is different to that of pregnenolone sulphate

European Journal of Pharmacology, Vol. 605, (1-3) : 78-86

Strömberg, Jessica; Lundgren, Per; Taube, Magdalena; et al.

A comparison of the pharmacological properties of recombinant human and rat α₁β₂γ_2L GABA_A receptors in Xenopus oocytes

Clinical and experimental pharmacology & physiology, Vol. 35, (9) : 1002-1011

Rahman, Mozibur; Borra, Vijaya B; Isaksson, Monica; et al.

Neurosteroids 3beta, 20 (R/S)-pregnandiols decrease offset rate of the GABA-site activation at the recombinant GABA(A) receptor.

Eur J Pharmacol, Vol. 586, (1-3) : 67-73

Wang, Ming-De; Borra, Vijaya Bhaskar; Strömberg, Jessica; et al.

3Beta-hydroxysteroids and pregnenolone sulfate inhibit recombinant rat GABA(A) receptor through different channel property.

European Journal of Pharmacology, Vol. 557, (2-3) : 124-131

Wang, Ming-De; Rahman, Mozibur; Zhu, Di; et al.

Neuroactive steroid effects on cognitive functions with a focus on the serotonin and GABA systems.

Brain Research Reviews, Vol. 51, (2) : 212-239

Birzniece, Vita; Bäckström, Torbjörn; Johansson, Inga-Maj; et al.

GABA-site antagonism and pentobarbital actions do not depend on the α-subunit type in the recombinant rat GABA-A receptor

Acta Physiologica, Vol. 187, (4) : 479-488

Mozibur, Rahman; Zhu, Di; Lindblad, Charlotte; et al.

Neurosteroid modulation of recombinant rat alpha5beta2gamma2L and alpha1beta2gamma2L GABA(A) receptors in Xenopus oocyte.

Eur J Pharmacol, Vol. 547, (1-3) : 37-44

Rahman, Mozibur; Lindblad, Charlotte; Johansson, Inga-Maj; et al.

Pregnenolone sulfate and zinc inhibit recombinant rat GABAA receptor through different channel property

Acta Physiologica, Vol. 188, (3/4) : 153-163

Wang, Ming-De; Rahman, Mozibur; Zhu, Di; et al.

Isoallopregnanolone; an antagonist to the anaesthetic effect of allopregnanolone in male rats

European Journal of Pharmacology, Amsterdam: North-Holland 2005, Vol. 512, (1) : 15-21

Bäckström, Torbjörn; Wahlström, Göran; Wahlström, Kerstin; et al.

Protons inhibit Cl- conductance by direct or allosteric interaction with the GABA-binding site in the rat recombinant alpha(1)beta(2)gamma(2L) and alpha(1)beta(2) GABA(A) receptor

European Journal of Pharmacology, Amsterdam: Elsevier 2005, Vol. 528, (1-3) : 1-6

Wang, Ming-De; Rahman, Mozibur; Zhu, Di

Selective antagonism of 5alpha-reduced neurosteroid effects at GABA(A) receptors

Molecular Pharmacology, Vol. 65, (5) : 1191-1197

Mennerick, Steven; He, Yejun; Jiang, Xin; et al.

Pathogenesis in menstrual cycle-linked CNS disorders.

Annals of the New York Academy of Sciences, Vol. 1007 : 42-53

Bäckström, Torbjörn; Andersson, Agneta; Andreén, Lotta; et al.

The role of hormones and hormonal treatments in premenstrual syndrome

CNS Drugs, Vol. 17, (5) : 325-342

Bäckström, Torbjörn; Andreen, Lotta; Birzniece, Vita; et al.

Allopregnanolone-stimulated GABA-mediated chloride ion flux is inhibited by 3beta-hydroxy-5alpha-pregnane-20-one (isoallopregnanolone)

Brain Research, Vol. 982, (1) : 45-53

Lundgren, Per; Strömberg, Jessica; Bäckström, Torbjörn; et al.

Ovarian hormone effects on 5-hydroxytryptamine (2A) and 5-hydroxytryptamine (2C) receptor mRNA expression in the ventral hippocampus and frontal cortex of female rats.

Neuroscience Letters, Vol. 319, (3) : 157-161

Birzniece, Vita; Johansson, I-M; Wang, MD; et al.

3beta-hydroxypregnane steroids are pregnenolone sulfate-like GABA(A) receptor antagonists

Journal of Neuroscience, Vol. 22, (9) : 3366-3375

Wang, Mingde; He, Yejun; Eisenman, Lawrence N; et al.

Serotonin 5-HT(1A) receptor mRNA expression in dorsal hippocampus and raphe nuclei after gonadal hormone manipulation in female rats.

Neuroendocrinology, Vol. 74, (2) : 135-142

Birzniece, Vita; Johansson, I-M; Wang, MD; et al.

Chronic allopregnanolone elevation cause altered plaque production in Swe/PS1 mice

Bengtsson, Sara; Lundgren, Per; Gouissem, Samira; et al.

Does chronic endogenous exposure to neuroactive steroids change receptor sensitivity to allopregnanolone in humans?

Hedström, Helena; Bäckström, Torbjörn; Bixo, Marie; et al.

Allopregnanolone, a GABA-A receptor agonist, decreases gonadotropin levels in healthy fertile women but not in women with polycystic ovary syndrome

Hedström, Helena; Bäckström, Torbjörn; Wang, Mingde; et al.

Functional difference between recombinant human and rat α1β2γ2L GABAA receptors

Rahman, Mozibur; Isaksson, Monica; Johansson, Inga-Maj; et al.

The neuroactive steroid 5beta-pregnane-3beta, 20(R)-diol alters the kinetic properties of the GABA-A receptor differently from pregnenolone-sulfate

Strömberg, Jessica; Lundgren, Per; Taube, Magdalena; et al.

S100A9-driven amyloid-neuroinflammatory cascade in traumatic brain injury as a risk factor for Alzheimer’s disease

Wang, Chao; Iashchishyn, Igor; Nyström, Sofie; et al.

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