Publikationer

Publikationer 2023 till och med april

1. Hollowell T, Sewe MO, Rocklöv J, Obor D, Odhiambo F, Ahlm C. Public health determinants of child malaria mortality: a surveillance study within Siaya County, Western Kenya. Malar J. 2023 Feb 23;22(1):65. doi: 10.1186/s12936-023-04502-9. PMID: 36823600; PMCID: PMC9948786.

2. Wilkman L, Ahlm C, Evander M, Lwande OW. (2023). Mosquito-borne viruses causing human disease in Fennoscandia-Past, current, and future perspectives. Frontiers of Medicine (Lausanne). Mar 27;10:1152070. doi: 10.3389/fmed.2023.1152070.

3. Tükenmez, H.*; Singh, P.; Sarkar, S.; Çakır, M.; Oliveira, A. H; Lindgren, C.; Vaitkevicius, K.; Bonde, Mari.; Sauer-Eriksson, A. E.; Almqvist, F.*; Johansson, J.* A highly substituted ring fused 2-pyridone targeting PrfA and the efflux regulator BrtA in Listeria monocytogenes. mBio, 2023, Accepted.

4. Sarkar, S.; Mayer Bridwell, A.; Good, J.; McKee, S.; Valenta, J.; Harrison, G.; Flentie, K.; Henry, F.; Wixe, T.; Demirel, P.; Vagolu, S.; Tønjum, T.; Stallings, C. L.*; Almqvist, F.* Design, synthesis, and evaluation of novel ∆2-thiazolino 2-pyridone derivatives that potentiate isoniazid activity in an isoniazid-resistant Mycobacterium tuberculosis mutant. Manuscript Submitted to J. Med. Chem. (minor revision).

5. Hainzl, T.; Bonde, M.; Almqvist, F.; Johansson, J.; Sauer-Eriksson, A. E. Structural determinants of activation and DNA recognition by the global transcription factor CodY. Manuscript Submitted to Nucleic Acids Research. (Resubmitted after minor revision).

6. Harrison, G.A.; Cho, K.; Wang, E.R.; Sarkar, S.; Almqvist, F.; Patti, G. J.; Stallings C. L.; Inducing vulnerability to InhA inhibition restores isoniazid susceptibility in drug resistant Mycobacterium tuberculosis. Manuscript Submitted.

7. Doran, M., Dahlberg T. , Baker J., Andersson M., & Bullitt E. (2023) Three structural solutions for bacterial adhesion pilus stability and superelasticity In print Structure

8. Nilsson, D. , Jonsmoen, UL., Malyshev, D.,  Öberg, R., Wiklund R., & Andersson, M., (2023) Physico-chemical characterization of single bacteria and spores using optical tweezers In print Research in Microbiology

9. Patkowski, J., Dahlberg, T., Amin, H., Gahlot, D., Vijayrajratnam, S., Vogel, J.,  Francis, M.,  Baker, J.. Andersson, M., & Costa, T., (2023) The F-pilus biomechanical adaptability accelerates conjugative dissemination of antimicrobial resistance and biofilm formation In print Nature Communications

10. Alakpa, E. V, Bahrd, A., Wiklund, K., Andersson, M., Novikov, L. N., Ljungberg, C., & Kelk, P. (2023). Bioprinted Schwann and Mesenchymal Stem Cell Co-Cultures for Enhanced Spatial Control of Neurite Outgrowth. Gels, 9(3), 172. https://doi.org/10.3390/gels9030172

11. Valijam, S., Salehi, A., & Andersson, M. (2023). Design of a low-voltage dielectrophoresis lab-on-the chip to separate tumor and blood cells. Microfluidics and Nanofluidics, 27(3), 22. https://doi.org/10.1007/s10404-023-02632-9

12. Malyshev, D., Jones, I. A., McKracken, M., Öberg, R., Harper, G. M., Joshi, L. T., & Andersson, M. (2023). Hypervirulent R20291 Clostridioides difficile spores show disinfection resilience to sodium hypochlorite despite structural changes. BMC Microbiology, 23(1), 59. https://doi.org/10.1186/s12866-023-02787-z

13. Lidström T, Cumming J, Gaur R, Frängsmyr L, Pateras IS, Mickert MJ, Franklin O, Forsell MNE, Arnberg N, Dongre M, Patthey C, Öhlund D. (2023). Extracellular Galectin 4 Drives Immune Evasion and Promotes T-cell Apoptosis in Pancreatic Cancer. Cancer Immunol Res. 11(1):72-92. doi: 10.1158/2326-6066.CIR-21-1088.

14. Breidenstein, A., ter Beek, J., and Berntsson, R. P.-A. # (2023). Structural and functional characterization of TraI from pKM101 reveals basis for DNA processing. Life Science Alliance, 6(4), e202201775 DOI: 10.26508/lsa.202201775

15. Sun,  W-S., Lassinantti, L., Järvå, M., Schmitt, A., ter Beek, J., and. Berntsson, R. P.-A.# (2023) Structural foundation for the role of enterococcal PrgB in conjugation, biofilm formation and virulence. eLife, accepted

16. Russell AJC, Sanderson T, Bushell E, Talman AM, Anar B, Girling G, Hunziker M, Kent RS, Martin JS, Metcalf T, Montandon R, Pandey V, Pardo M, Roberts AB, Sayers C, Schwach F, Choudhary JS, Rayner JC, Voet T, Modrzynska KK, Waters AP, Lawniczak MKN, Billker O (2023) Regulators of male and female sexual development are critical for the transmission of a malaria parasite. Cell Host Microbe 31(2).

17. IM Marreiros, S Marques, A Parreira , V Mastrodomenico, BC Mounce, CT arris, BF Kafsack, O Billker, V Zuzarte-Luís, MM Mota. (2023) A non-canonical sensing pathway mediates Plasmodium adaptation to amino acid deficiency Communications Biology. 6 (1), 205.

18. T Chookajorn, O Billker (2023) Sideways: road to gene-by-gene functional screening in malaria parasites. Trends in Parasitology.

19. Aurass P, Kim S, Pinedo V, Cava F and Ralph R. Isberg. Identification of genes required for long term survival of L. pneumophila in water. mSphere. 2023 Mar 29:e0045422

20. Daitch AK, et al, Cava F, Gabelli SB, Goley ED. EstG is a novel esterase required for cell envelope integrity in Caulobacter. Curr Biol. 2023 Jan 23;33(2):228-240.e7.

21. Sit B, Srisuknimit V, Bueno E, Zingl FG, Hullahalli K, Cava F#, Waldor MK. Undecaprenyl phosphate translocases confer conditional microbial fitness. Nature. 2023 Jan;613(7945):721-8.

22. Longjun Pu, Lina Zhao, Qiongxuan Lu, Changchun Chen (2023). Hypoxia induces food leaving in C. elegans. microPublication Biology. DOI: 10.17912/micropub.biology.000776.

23. Erttmann, S.F. and N.O. Gekara. Protocol for isolation of microbiota-derived membrane vesicles from mouse blood and colon. STAR Protocols 4, 102046, March 17, 2023.

24. Mutsaers M, C Springer Engdahl, L Wilkman, C Ahlm, M Evander, OW Lwande (2023). Vector competence of Anopheles stephensi for o’nyong-nyong virus – A risk for global virus spread. Parasites & Vectors. Accepted 2023-03-02.

25. Mittler E, Serris A, Esterman ES, Florez C, Polanco LC, O’Brien CM, Slough MM, Tynell J, Gröning R, Sun Y, Abelson DM, Wec AZ, Haslwanter D, Keller M, Ye C, Bakken RR, Jangra RK, Dye JM, Ahlm C, Rappazzo G, Ulrich RG, Zeitlin L, Geoghegan JC, Bradfute SB, Sidoli S, Forsell MNE, Strandin T, Rey FA, Herbert AS, Walker LM, Chandran K, Guardado-Calvo P. Structural and mechanistic basis of neutralization by a pan-hantavirus protective antibody. Sci Transl Med, (Accepted 230424, not yet on pubmed).

26. Vikström L, Fjällström P, Gwon YD, Sheward DJ, Byström JW, Evander M, Bladh O, Widerström M, Molnar C, Rasmussen G, Bennet L, Åberg M, Björk J, Tevell S, Thålin C, Blom K, Klingström J, Murrell Ben, Ahlm C, Normark J, Johansson AF, Forsell MNE. Vaccine-induced correlate of protection against fatal COVID-19 in older and frail adults during waves of neutralization-resistant variants of concern: an observational study. Lancet Regional Health Europe (Accepted 20230413, not yet on pubmed).

27. Chernyshev M, Sakharkar M, ConnorRI, Dugan HL, Sheward DJ, Rappazzo G, Stålmarck A, Forsell MNE, Wright PF, Corcoran M, Murrell B, Walker LM and Karlsson Hedestam GB. mRNA-1273 vaccination of SARS-CoV-2-infected individuals expands a broad range of clonally diverse affinity-matured B cell lineages. Nat Commun. 2023 Apr 19;14(1):2249. doi: 10.1038/s41467-023-37972-1.PMID: 37076511.

28. Cable J, Graham BS, Koup RA, Seder RA, Karikó K, Pardi N, Barouch DH, Sharma B, Rauch S, Nachbagauer R, Forsell MNE, Schotsaert M, Ellebedy AH, Loré K, Irvine DJ, Pilkington E, Tahtinen S, Thompson EA, Feraoun Y, King NP, Saunders K, Alter G, Moin SM, Sliepen K, Hedestam GBK, Wardemann H, Pulendran B, Doria-Rose NA, He WT, Juno JA, Ataca S, Wheatley AK, McLellan JS, Walker LM, Lederhofer J, Lindesmith LC, Wille H, Hotez PJ, Bekker LG. Progress in vaccine development for infectious diseases-a Keystone Symposia report. Ann N Y Acad Sci. 2023 Apr 5. doi: 10.1111/nyas.14975. Epub ahead of print. PMID: 37020354.

29. Byström JW, Vikström L, Rosendal E, Gröning R, Gwon YD, Nilsson E, Sharma A, Espaillat A, Hanke L, McInerney G, Puhar A, Cava F, Karlsson Hedestam GB, Thunberg T, Monsen T, Elgh F, Evander M, Johansson AF, Överby AK, Ahlm C, Normark J, Forsell MN. At-home sampling to meet geographical challenges for serological assessment of SARS-CoV-2 exposure in a rural region of northern Sweden, March to May 2021: a retrospective cohort study. Euro Surveill. 2023 Mar;28(13):2200432. doi: 10.2807/1560-7917.ES.2023.28.13.2200432. PMID: 36995373; PMCID: PMC10064644.

30. Pateras, I.S., Williams, C., Gianniou, D.D., Margetis, A.T., Avgeris, M., Rousakis, P., Legaki, A.I., Mirtschink, P., Zhang, W., Panoutsopoulou, K., et al. (2023). Short term starvation potentiates the efficacy of chemotherapy in triple negative breast cancer via metabolic reprogramming. J Transl Med 21, 169. 10.1186/s12967-023-03935-9

31. MS1. Luke Clifton, Hanna Wacklin-Knecht, , Jörgen Åden, Ameeq Ul Mushtaq, Tobias Sparrman and Gerhard Gröbner: “Creation of distinctive Bax-lipid complexes at mitochondrial membrane surfaces drives pore formation to initiate apoptosis.” Science Advances (2023) under revision. As preprint https://biorxiv.org/cgi/content/short/2022.11.01.514672v1

32. Oliveira AH, Tiensuu T, Guerreiro DN, Tükenmez H, Dessaux C, García-del Portillo F, O’Byrne C and Johansson J# (2023) The virulence and infectivity of Listeria monocytogenes are not substantially altered by elevated SigB activity Infect & Immun, Accepted #Corresponding author

33. Tran BM, Linnik DS, Punter CM, Śmigiel WM, Mantovanelli L, Iyer A, O'Byrne C, Abee T, Johansson J, Poolman B. (2023) Super-resolving microscopy reveals the localizations and movement dynamics of stressosome proteins in Listeria monocytogenes. Commun Biol. 6(1):51.

34. Sun, T.A., Lind, P.A. (2023) Distribution of mutation rates challenges evolutionary predictability. Microbiology (Accepted) Pre-print at bioRxiv 10.1101/2022.12.12.518962

35. Stael, S., Sabljić, I., Audenaert, D., Andersson, T., Tsiatsiani, L., Kumpf, R.P., Vidal-Albalat, A., Lindgren, C., Vercammen, D., Jacques, S., Nguyen, L., Njo, M.F., Fernández-Fernández, A.D., Beunens, T., Timmerman, E., Gevaert, K., Ståhlberg, J., Bozhkov, P., Linusson, A., Beeckman, T., Van Breusegem, F., (2023) Structure-function analysis of a calcium-independent metacaspase reveals a novel proteolytic pathway for lateral root emergence, Proc. Natl. Acad. Sci. U.S.A., In press.

36.   Rullo, M., La Spada, G., Miniero, D.V., Gottinger, A., Catto, M., Delre, P., Mastromarino, M., Latronico, T., Marchese, S., Mangiatordi, G.F., Binda, C., Linusson, A., Liuzzi, G.M., Pisani, L., (2023) Bioisosteric replacement based on 1,2,4-oxadiazoles in the discovery of 1H-indazole-bearing neuroprotective MAO B inhibitors. Eur. J. Med. Chem. In press.

37. Vidal-Albalat, A., Kindahl, T., Rajeshwari, R., Lindgren, C., Forsgren, N., Kitur, S., Sela Tengo, L., Ekström, F., Kamau, L., Linusson, A. (2023) Structure-Activity Relationships Reveal Beneficial Selectivity Profiles of Inhibitors Targeting Acetylcholinesterase of Disease-Transmitting Mosquitoes. J. Med. Chem. In press.

38. Pulkkinen LIA, Barrass SV, Lindgren M, Pace H, Överby AK, Anastasia M, Bally M, Lundmark R, Butcher SJ. Simultaneous membrane and RNA binding by Tick-Borne Encephalitis Virus capsid protein. PLOS pathogens, Feb 14;19(2):e1011125. doi: 10.1371/journal.ppat.1011125. Online ahead of print. PMID: 36787339 (2023) Co-corresponding senior author.

39. Larsson E, Morén B, McMahon KA, Parton RG, Lundmark R; Dynamin2 functions as an accessory protein to reduce the rate of caveola internalization. J Cell Biol. Apr 3;222(4):e202205122. doi: 10.1083/jcb.202205122. Epub 2023 Feb 2.PMID: 36729022 (2023)

40. Maccaferri, N., Gabbani, A., Pineider F., Kaihara, T., Tapani, T., and Vavassori, P. (2023). Magnetoplasmonics in confined geometries: current challenges and future opportunities. Applied Physics Letters 122, 120502. 10.1063/5.0136941.

41. Zhao, Y. Iarossi, M., Maccaferri, N., Deleye, L., Melle, G., Huang, J.-A., Iachetta, G., D’Amora, M., Tantussi, F., and De Angelis, F. (2023). Hyperbolic metamaterial nanoparticles random array for thermoplasmonics in the II and III near-infrared windows. Applied Physics Letters 122, 052201. 10.1063/5.0132172.

42. YaFang Mei, Qian Zhang, Maria Hammond, Jie Song, Zongwei Fang, Hongxing Zhao Marene Landgren. Analysis of the SARS-CoV-2 spike protein revealed that blocked receptor-binding domain antigenicity decreases the production of neutralizing antibodies in vivo   BioRxiv (2023). doi: https://doi.org/10.1101/2023.02.23.529497

43. Björsell T, Sundh J, Lange A, Ahlm C, Forsell MNE, Tevell S, Blomberg A, Edin A, Normark J, Cajander J. Risk factors for impaired respiratory function post COVID-19: a prospective cohort study of non-hospitalized and hospitalized patients, Journal of Internal Medicine, February 2023; 00:1–15.

44. Ahmad I, Edin A, Granvik C, Kumm Persson L, Tevell S, Månsson E, Magnuson A, Marklund I, Persson I-L, Kauppi A, Ahlm C, Forsell M.N.E, Sundh J, Lange A, Cajander S, Normark J. High prevalence of persistent symptoms and reduced health-related quality of life 6 months after COVID-19, Frontiers in Public Health February 2023, 2;11:1104267

45. Elena Yunda, Mareike Gutensohn, Madeleine Ramstedt, Erik Björn* (2023) Methylmercury formation in biofilms of Geobacter sulfurreducens, Frontiers in Microbiology, 14, 1079000 (10 p.) (https://doi.org/10.3389/fmicb.2023.1079000 )

46. Madeleine Ramstedt*, Andrey Shchukarev (2o23) XPS spectra from nucleobases, DNA and RNA, accepted for publication in Surface Science Spectra

47. Puértolas-Balint F. & Schroeder B.O. (2023). Intestinal α-defensins play a minor role in modulating the small-intestinal microbiota composition as compared to diet. Accepted in Microbiology Spectrum.

48. Naama M., Telpaz S., Awad A., Ben-Simon S., Harshuk Shabso S., Modilevsky S., Rubin E., Sawaed J., Zelik L., Zigdon M., Fadida N., Turjeman S., Werbner M., Wongkuna S., Feeney R., Schroeder B.O., Nyska A., Nuriel-Ohayon M., Bel S. (2023). Autophagy controls mucus secretion from intestinal goblet cells by alleviating ER stress. Cell Host & Microbe 31(3):433-446.e4.

49. Birchenough G.M.B.#, Schroeder B.O.#, Sharba S., Arike L., Recktenwald C.V., Puértolas-Balint F., Subramani M.V., Hansson K.T., Yilmaz B., Lindén S.K., Bäckhed F., Hansson G.C. (2023). Muc2-Dependent Microbial Colonization of the Jejunal Mucus Layer is Diet Sensitive and Confers Resistance to Enteric Pathogen Infection. Cell Reports 42(2):112084. (#contributed equally)

50. Bastidas, R.J., Kędzior, M., Dolat, L., Sixt, B.S., Pruneda, J.N., and Valdivia, R.H. (2023). The acetylase activity of Cdu1 protects Chlamydia effectors from degradation to regulate bacterial exit from infected cells. bioRxiv, doi: 10.1101/2023.02.28.530337.

51. Farooq, Z., Sjödin, H., Semenza, J. C., Tozan, Y., Sewe, M. O., Wallin, J., & Rocklöv, J. (2023). European projections of West Nile virus transmission under climate change scenarios. One Health, 16, 100509. https://doi.org/10.1016/j.onehlt.2023.100509. (Impact Factor: 9.0; Citations: 0)

52. Behren, S., Yu, J., Pett, C., Schorlemer, M. Heine, V., Fischöder, T., Elling, L., Westerlind, U.* (2023). Fucose Binding Motifs on Mucin Core Glycopeptides Impact Bacterial Lectin Recognition. Angew. Chem. Int. Ed., e202302437, https://doi.org/10.1002/anie.202302437 IF=16.823

53. Behren, S., Schorlemer, M., Schmidt, G., Aktories, K., Westerlind, U.* (2023) Antibodies Directed Against GalNAc- and GlcNAc-O-Tyrosine Posttranslational Modifications – a New Tool for Glycoproteomic Detection, Chem. Eur. J., e202300392, https://doi.org/10.1002/chem.202300392 IF=5.020

54. Behren, S., Westerlind, U.* (2023). Novel approaches to design glycan-based antibacterial inhibitors. Eur. J. Org. Chem. 26, e2022007, https://doi.org/10.1002/ejoc.202200795. IF= 3.261

55. Wikner, J., and Vikstrom, K. (2023). Extensive prokaryotic maintenance respiration in the sea influenced by osmoregulation. Frontiers in Marine Science 10, 1070070. 10.3389/fmars.2023.1070070.

56. Wikner, J., Vikström, K., and Verma, A. (2023). Regulation of Marine Plankton Respiration: A test of models. Frontiers in Marine Science. 10.3389/fmars.2023.1134699.

57. Nam, K & Wolf-Watz, M.. (2023). Protein Dynamics: The Future is Bright and Complicated!  Journal of Structural Dynamics.. 10, 014301. Invited perspective article.

58. Dulko-Smith, B., Ojeda-May, P., Ådén, J.,  Wolf-Watz, Magnus; Nam, Kwangho. (2023).  Mechanistic basis for a connection between the catalytic step and slow opening dynamics of adenylate kinase. Journal of Chemical Information and Modeling. 63, 1556-1569.

59.   Wu, Y.W. (2023). Controlling cellular activities with light. Nat Methods 20,57-358. 10.1038/s41592-022-01745-3.

60. Filip Mihalic, Leandro Simonetti, Girolamo Giudice, Marie Rubin Sander, Richard Lindqvist, Marie Berit Akprioro Peters, Caroline Benz, Eszter Kassa, Dilip Badgujar, Raviteja Inturi, Muhammad Ali, Izabella Krystkowiak, Ahmed Sayadi, Eva Andersson, Hanna Aronsson, Ola Söderberg, Doreen Dobritzsch, Evangelia Petsalaki, Anna K Överby, Per Jemth, Norman E. Davey, Ylva Ivarsson. Large-scale phage-based screening reveals extensive pan-viral mimicry of host short linear motifs, Accepted for publication Nature Communication 2023 April 12 2022.06.19.496705; doi: https://doi.org/10.1101/2022.06.19.496705

61. Chotiwan N*, Rosendal E*, Willekens SMA*, Schexnaydre E, Nilsson E, Lindqvist R, Hahn M, Mihai IS, Morini F, Zhang J, Ebel GD, Carlson LA, Henriksson J, Ahlgren U, Marcellino D, Överby AK. Type I interferon shapes brain distribution and tropism of tick-borne flavivirus. Nature Communications 2023 Apr 10;14(1):2007. doi: 10.1038/s41467-023-37698-0. PMID: 37037810.

 

Publikationer 2022

1. Abdelrahim NA, Mohammed N, Evander M, Ahlm C, Fadl-Elmula IM. (2022).  Viral meningitis in Sudanese children: Differentiation, etiology and review of literature. Medicine (Baltimore) 101(46):e31588. doi: 10.1097/MD.0000000000031588.

2. Abdelrahim NA, Mohamed N, Evander M, Ahlm C, Fadl-Elmula IM. (2022). Human herpes virus type-6 is associated with central nervous system infections in children in Sudan. Afr J Lab Med 11(1):1718. doi: 10.4102/ajlm.v11i1.1718. PMID: 36263389;

3. Tuiskunen Bäck A, Rasmuson J, Thunberg T, Rankin G, Wigren Byström J, Andersson C, Sjödin A, Forsell M, Ahlm C. Clinical and genomic characterisation of a fatal Puumala orthohantavirus case with low levels of neutralising antibodies. Infect Dis (Lond). 2022 Oct;54(10):766-772. doi: 10.1080/23744235.2022.2076904. Epub 2022 Jun 17. PMID: 35713235; PMCID: PMC9908776.

4. Ahsan, U., Mushtaq, F., Saleem, S., Malik, A., Sarfaraz, H., Shahzad, M., Uhlin, B.E., and Ahmad, I.(2022). Emergence of high colistin resistance in carbapenem resistant Acinetobacter baumannii in Pakistan and its potential management through immunomodulatory effect of an extract from Saussurea lappa. Frontiers in Pharmacology 13. 10.3389/fphar.2022.986802.

5. Nye, T.M.; Tükenmez, H.; Singh, P.; Flores-Mireles, A.L.; Obernuefemann, C.L.; Pinkner, J.S.; Sarkar, S.; Bonde, M.; Lindgren, A.E.; Dodson, K.W.; and Johansson, J.; Almqvist, F.* Caperon, M.G.*; Hultgren, S.J.* Ring-fused 2-pyridones effective against multidrug-resistant Gram-positive pathogens and synergistic with standard-of-care antibiotics. Proc. Natl. Acad. Sci. USA. 2022;119(43): e2210912119

6. Malyshev, D., Dahlberg, T., Öberg, R., Landström, L., & Andersson, M. (2022). Reference Raman spectrum and mapping of Cryptosporidium parvum oocysts. Journal of Raman Spectroscopy, 53(7), 1293–1301. https://doi.org/10.1002/jrs.6361

7. Nilsson, D. P. G., Holmgren, M., Holmlund, P., Wåhlin, A., Eklund, A., Dahlberg, T., Wiklund, K., & Andersson, M. (2022). Patient-specific brain arteries molded as a flexible phantom model using 3D printed water-soluble resin. Scientific Reports, 12(1), 10172. https://doi.org/10.1038/s41598-022-14279-7

8. Malyshev, D., Robinson, N. F., Öberg, R., Dahlberg, T., & Andersson, M. (2022). Reactive oxygen species generated by infrared laser light in optical tweezers inhibits the germination of bacterial spores. Journal of Biophotonics, 15(8). https://doi.org/10.1002/jbio.202200081

9. Doran, M., Dahlberg, T., Baker, J., Andersson, M., & Bullitt, E. (2022). CS20 bridge the gap between class 1 and class 5 bacterial adhesion pili. Biophysical Journal, 121(3), 168a. https://doi.org/10.1016/j.bpj.2021.11.1893

10.   Pakharukova, N., Malmi, H., Tuittila, M., Dahlberg, T., Ghosal, D., Chang, Y.-W., Myint, S. L., Paavilainen, S., Knight, S. D., Lamminmäki, U., Uhlin, B. E., Andersson, M., Jensen, G., & Zavialov, A. V. (2022). Archaic chaperone–usher pili self-secrete into superelastic zigzag springs. Nature, 609(7926), 335–340. https://doi.org/10.1038/s41586-022-05095-0

11. Malyshev, D., Öberg, R., Landström, L., Andersson, P. O., Dahlberg, T., & Andersson, M. (2022). pH-induced changes in Raman, UV–vis absorbance, and fluorescence spectra of dipicolinic acid (DPA). Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 271, 120869. https://doi.org/10.1016/j.saa.2022.120869

12. Malyshev, D., Öberg, R., Dahlberg, T., Wiklund, K., Landström, L., Andersson, P. O., & Andersson, M. (2022). Laser induced degradation of bacterial spores during micro-Raman spectroscopy. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy, 265, 120381. https://doi.org/10.1016/j.saa.2021.120381

13. Dahlberg, T., Baker, J. L., Bullitt, E., & Andersson, M. (2022). Unveiling molecular interactions that stabilize bacterial adhesion pili. Biophysical Journal, 121(11), 2096–2106. https://doi.org/10.1016/j.bpj.2022.04.036

14. Orädd, F., Steffen, J.H., Gourdon, P., Andersson, M. Copper binding leads to increased dynamics in the regulatory N-terminal domain of full-length human copper transporter ATP7B. PLoS Computational Biology. 18(9):e1010074, (2022).

15. Salustros, N., Grønberg, C., Abeyrathna, N.S., Lyu, P., Orädd, F., Wang, K., Andersson, M., Meloni, G., Gourdon, P. Structural basis of ion-uptake in P1B-type ATPases. Nature Communications. 13(1):1-11, (2022).

16. Wiuf, A., Steffen, J.H., Becares, E.R., Grønberg, C., Mahato, D.R., Rasmussen, S.G.F., Andersson, M., Croll, T.,  Gotfryd, K., Gourdon, P. The two-domain elevator-type mechanism of zinc-transporting ZIP proteins. Science Advances. 8(28):eabn4331, (2022).

17. Li P., Nayeri, N., Górecki, K., Becares, E.R., Wang, K., Mahato, D.R., Andersson, M., Abeyrathna, S.S., Lindkvist‐Petersson, K., Meloni, G., Missel, J.W., Gourdon, P. PcoB is a defense outer membrane protein that facilitates cellular uptake of copper. Protein Science. 31(7):e4364, (2022).

18. Benkő M, Aoki K, Arnberg N, Davison AJ, Echavarría M, Hess M, Jones MS, Kaján GL, Kajon AE, Mittal SK, Podgorski II, San Martín C, Wadell G, Watanabe H, Harrach B, Ictv Report Consortium. (2022). ICTV Virus Taxonomy Profile: Adenoviridae 2022. J Gen Virol. 103(3):001721. doi: 10.1099/jgv.0.001721.

19. Persson BD, Nord S, Lindqvist R, Danskog K, Överby AK, Kohl A, Willison HJ, Lenman A, Arnberg N. (2022). BAF45b Is Required for Efficient Zika Virus Infection of HAP1 Cells. Viruses. Oct 6;13(10):2007. doi: 10.3390/v13102007.

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104. Staessen JA, Wendt R, Yu YL, Kalbitz S, Thijs L, Siwy J, Raad J, Metzger J, Neuhaus B, Papkalla A, von der Leyen H, Mebazaa A, Dudoignon E, Spasovski G, Milenkova M, Canevska-Taneska A, Psichogiou M, Rajzer MW, Fulawka L, Dzitkowska-Zabielska M, Weiss G, Feldt T, Stegemann M, Normark J, Zoufaly A, Schmiedel S, Seilmaier M, Rumpf B, Banasik M, Krajewska M, Catanese L, Rupprecht H, Czerwienska B, Peters B, Nilsson Å, Rothfuss K, Lübbert C, Mischak H, Beige J, the CRIT-Cov-U investigators. Predictive performance and clinical application of COV50, a urinary proteomic biomarker in early COVID-19 infection: a cohort study, Lancet digital health, 2022 Oct;4(10):e727-e737.

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Publikationer 2021

1. Maleki KT, Tauriainen J, García M, Kerkman PF, Christ W, Dias J, Wigren Byström J, Leeansyah E, Forsell MN, Ljunggren HG, Ahlm C, Björkström NK, Sandberg JK, Klingström J. (2021). MAIT cell activation is associated with disease severity markers in acute hantavirus infection. Cell Rep Med 2(3):100220.

2. Bortz RH 3rd, Florez C, Laudermilch E, Wirchnianski AS, Lasso G, Malonis RJ, Georgiev GI, Vergnolle O, Herrera NG, Morano NC, Campbell ST, Orner EP, Mengotto A, Dieterle ME, Fels JM, Haslwanter D, Jangra RK, Celikgil A, Kimmel D, Lee JH, Mariano MC, Nakouzi A, Quiroz J, Rivera J, Szymczak WA, Tong K, Barnhill J, Forsell MNE, Ahlm C, Stein DT, Pirofski LA, Goldstein DY, Garforth SJ, Almo SC, Daily JP, Prystowsky MB, Faix JD, Fox AS, Weiss LM, Lai JR, Chandran K. (2021). Single-Dilution COVID-19 Antibody Test with Qualitative and Quantitative Readouts. mSphere 6(2):e00224-21. doi: 10.1128/mSphere.00224-21.

3. Tükenmez, H. *; Sarkar, S.; Anoosheh, S.; Kruchanova, A.; Edström, I.; Harrison, G. A.; Stallings, C. L.; Almqvist, F.; Larsson, C. * Mycobacterium tuberculosis Rv3160c is a TetR-like transcriptional repressor that regulates expression of the putative oxygenase Rv3161c. Sci Rep. 2021, 11, 1523.

4. Cairns, A. G.; Sarkar, S.; Singh, P.; Larsson, A.*; and Almqvist, F.* An efficient and scalable synthesis of thiazolo ring fused 2-pyridones using flow chemistry. ARKIVOC, 2021, Volume 2020, part vii, 365-378.

5. Tyagi, M.; Adolfsson, D.E.; Singh, P.; Ådén, J.; Jayaweera, S.W.; Gharibyan, A.; Bharate, J.B.; Kiss, A.; Sarkar, S.; Olofsson, A.; Almqvist, F.* Tandem Ring Opening/Intramolecular [2 + 2] Cycloaddition Reaction for the Synthesis of Cyclobutane Fused Thiazolino-2-Pyridones. J. Org. Chem. 2021; 86(23):16582-16592. doi: 10.1021/acs.joc.1c01875.

6. Bharate, J.B.; Ådén, J.; Gharibyan, A.; Adolfsson, D.E.; Jayaweera, S.W; Singh, P.; Vielfort, K.; Tyagi, M; Bonde, M.; Bergström, S.; Olofsson, A.; Almqvist, F.* K2S2O8-mediated coupling of 6-amino-7-aminomethyl-thiazolino-pyridones with aldehydes to construct amyloid affecting pyrimidine-fused thiazolino-2-pyridones. Org. Biomol. Chem., 2021, 19(44), 9758-9772. doi: 10.1039/d1ob01580j.

7. Kelly, R.; Cairns, A.G.; Ådén, J.; Almqvist, F.; Bemelmans, A-P.; Brouillet, E.; Patton, T.; McKernan, D.P.; Dowd, E.* The Small Molecule Alpha-Synuclein Aggregator, FN075, Enhances Alpha-Synuclein Pathology in Subclinical AAV Rat Models. Biomolecules, 2021, 11(11):1685. doi: 10.3390/biom11111685.

8. Brosge, F.; Singh, P.; Almqvist, F.; Bolm, C.; Selected applications of Meldrum's acid–a tutorial. Org. Biomol. Chem., 2021,19(23), 5014-5027.

9. Reithuber, E.; Wixe, T.; Ludwig, K.C.; Müller, A.; Uvell, H.; Grein, F.; Lindgren, A.E.G.; Muschiol, S.; Nannapaneni, P.; Eriksson, A.; Schneider, T.; Normark, S.; Henriques-Normark, B. *; Almqvist, F. *; Mellroth, P.* THCz: Small molecules with antimicrobial activity that block cell wall lipid intermediates. Proc. Natl. Acad. Sci. USA. 2021;118(47):e2108244118. doi:10.1073/pnas.2108244118.

10. Näsström, T., Dahlberg, T., Malyshev, D., Ådén, J., Andersson, P. O., Andersson, M., & Karlsson, B. C. G. (2021). Synthetic NAC 71-82 Peptides Designed to Produce Fibrils with Different Protofilament Interface Contacts. International Journal of Molecular Sciences, 22(17), 9334. https://doi.org/10.3390/ijms22179334

11. Panadeiro, V., Rodriguez, A., Henry, J., Wlodkowic, D., & Andersson, M. (2021). A review of 28 free animal-tracking software applications: current features and limitations. Lab Animal, 50(9), 246–254. https://doi.org/10.1038/s41684-021-00811-1

12. Nilsson, D. P. G., Dahlberg, T., & Andersson, M. (2021). Step-by-step guide to 3D print motorized rotation mounts for optical applications. Applied Optics, 60(13), 3764. https://doi.org/10.1364/AO.422695

13. Baker, J. L., Dahlberg, T., Bullitt, E., & Andersson, M. (2021). Impact of an alpha helix and a cysteine–cysteine disulfide bond on the resistance of bacterial adhesion pili to stress. Proceedings of the National Academy of Sciences, 118(21), e2023595118. https://doi.org/10.1073/pnas.2023595118

14. Malyshev, D., Dahlberg, T., Wiklund, K., Andersson, P. O., Henriksson, S., & Andersson, M. (2021). Mode of Action of Disinfection Chemicals on the Bacterial Spore Structure and Their Raman Spectra. Analytical Chemistry, 93(6), 3146–3153. https://doi.org/10.1021/acs.analchem.0c04519

15. Dahlberg, T., & Andersson, M. (2021). Optical design for laser tweezers Raman spectroscopy setups for increased sensitivity and flexible spatial detection. Applied Optics, 60(16), 4519. https://doi.org/10.1364/AO.424595

16. Gronberg, C., Hu, Q., Mahato, D.R., Longhin, E., Salustros, N., Duellli, A., Lyu, P., Bågenholm, V., Eriksson, J., Rao, K.U., Henderson, D.I., Meloni, G., Andersson, M., Croll, T., Godaly, G., Wang, K., Gourdon, P. Structure and ion-release mechanism of PIB-4-type ATPases. Elife. 10:e73124, (2021).

17. Ygberg, S., Akkuratov, E.E., Howard, R.J., Taylan, F., Jans, D.C., Mahato, D.R., Katz, A., Kinoshita, P.F., Portal, B., Nennesmo, I., Lindskog, M., Karlish, S.J.D., Andersson, M., Lindstrand, A., Brismar, H., Aperia, A. A missense mutation converts the Na+,K+-ATPase into an ion channel and causes therapy-resistant epilepsy. Journal of Biological Chemistry. 297(6):101355, (2021).

18. Orädd, F., Ravishankar, H., Goodman, J., Rogne, P., Backman, L., Duelli, A., Pedersen, M.N., Levantino, M., Wolff, M., Wolf-Watz, M., Andersson, M. Tracking the ATP-binding response in adenylate kinase in real time. Science Advances. 7(47):eabi5514, (2021).

19. Orädd, F., Andersson, M. Tracking membrane protein dynamics in real time. Journal of Membrane Biology. 254:51-64, (2021).

20. Jakobsson J, Cotgreave I, Furberg M, Arnberg N, Svensson M. (2021). Potential Physiological and Cellular Mechanisms of Exercise That Decrease the Risk of Severe Complications and Mortality Following SARS-CoV-2 Infection. Sports (Basel). 9(9):121. doi: 10.3390/sports9090121.

21. Ballmann MZ, Raus S, Engelhart R, Kaján GL, Beqqali A, Hadoke PWF, van der Zalm C, Papp T, John L, Khan S, Boedhoe S, Danskog K, Frängsmyr L, Custers J, Bakker WAM, van der Schaar HM, Arnberg N, Lemckert AAC, Havenga M, Baker AH. (2021). Human AdV-20-42-42, a Promising Novel Adenoviral Vector for Gene Therapy and Vaccine Product Development. J Virol. 95(22):e0038721. doi: 10.1128/JVI.00387-21.

22. Arnberg N, Lenman A. (2021). Special Issue "Adenovirus Pathogenesis". Viruses. 10;13(6):1112. doi: 10.3390/v13061112.

23. Persson BD, John L, Rafie K, Strebl M, Frängsmyr L, Ballmann MZ, Mindler K, Havenga M, Lemckert A, Stehle T, Carlson LA, Arnberg N.  (2021). Human species D adenovirus hexon capsid protein mediates cell entry through a direct interaction with CD46. Proc Natl Acad Sci U S A. 118(3):e2020732118. doi: 10.1073/pnas.2020732118.

24. Alqabandi, M., de Franceschi, N., Maity, S., Miguet, N., Bally, M., Roos, W.H., Weissenhorn, W., Bassereau, P., and Mangenot, S. (2021). The ESCRT-III isoforms CHMP2A and CHMP2B display different effects on membranes upon polymerization. Bmc Biol 19. ARTN 66. 10.1186/s12915-021-00983-9.

25. Bally, M., Block, S., Hook, F., Larson, G., Parveen, N., and Rydell, G.E. (2021). Physicochemical tools for studying virus interactions with targeted cell membranes in a molecular and spatiotemporally resolved context. Anal Bioanal Chem 413, 7157-7178. 10.1007/s00216-021-03510-5.

26. Bernasconi, V., Norling, K., Gribonika, I., Ong, L.C., Burazerovic, S., Parveen, N., Schon, K., Stensson, A., Bally, M., Larson, G., et al. (2021). A vaccine combination of lipid nanoparticles and a cholera toxin adjuvant derivative greatly improves lung protection against influenza virus infection. Mucosal Immunol 14, 523-536. 10.1038/s41385-020-0334-2.

27. Trybala, E., Peerboom, N., Adamiak, B., Krzyzowska, M., Liljeqvist, J.A., Bally, M., and Bergstrom, T. (2021). Herpes Simplex Virus Type 2 Mucin-Like Glycoprotein mgG Promotes Virus Release from the Surface of Infected Cells. Viruses-Basel 13. ARTN 887. 10.3390/v13050887.

28. Lassinantti, L., Camacho, M.I., Erickson, R.J.B., Willett, J.L.E., De Lay, N.R., ter Beek, J., Dunny, G.M., Christie, P.J., and Berntsson, R.P.-A. # (2021). Enterococcal PrgU Provides Additional Regulation of Pheromone-Inducible Conjugative Plasmids. MSphere 6, e00264-21.

29. Tibúrcio M, Hitz E, Niederwieser I, Kelly G, Davies H, Doerig C, Billker O, Voss TS, Treeck M. (2021) A 39-Amino-Acid C-Terminal Truncation of GDV1 Disrupts Sexual Commitment in Plasmodium falciparum. mSphere 6(3) PMID: 34011691

30. Knöckel J, Dundas K, Yang ASP, Galaway F, Metcalf T, Gemert GV, Sauerwein RW, Rayner JC, Billker O, Wright GJ. (2021) Systematic Identification of Plasmodium falciparum Sporozoite Membrane Protein Interactions Reveals an Essential Role for the p24 Complex in Host Infection. Mol Cell Proteomics 20. PMID: 33515807

31. Miguel-Blanco C, Murithi JM, Benavente ED, Angrisano F, Sala KA, van Schalkwyk DA, Vanaerschot M, Schwach F, Fuchter MJ, Billker O, Sutherland CJ, Campino SG, Clark TG, Blagborough AM, Fidock DA, Herreros E, Gamo FJ, Baum J, Delves MJ (2021). The antimalarial efficacy and mechanism of resistance of the novel chemotype DDD01034957. Sci Rep. 2021;11(1):1888.

32. Chiappino-Pepe A, Pandey V, Billker O. (2021) Genome reconstructions of metabolism of Plasmodium RBC and liver stages. Curr Opin Microbiol. 2021;63:259-266.

33. Rafie, K., Lenman, A., Fuchs, J., Rajan, A., Arnberg, N., and Carlson, L.A. (2021). The structure of enteric human adenovirus 41-A leading cause of diarrhea in children. Science Advances 7.

34. Carroll, L.M., Buehler, A.J., Gaballa, A., Siler, J.D., Cummings, K.J., Cheng, R.A., and Wiedmann, M. (2021). Monitoring the Microevolution of Salmonella enterica in Healthy Dairy Cattle Populations at the Individual Farm Level Using Whole-Genome Sequencing. Front Microbiol 12, 763669. 10.3389/fmicb.2021.763669.

35. Carroll, L.M., Pierneef, R., Mathole, M., and Matle, I. (2021). Genomic Characterization of Endemic and Ecdemic Non-typhoidal Salmonella enterica Lineages Circulating Among Animals and Animal Products in South Africa. Front Microbiol 12, 748611. 10.3389/fmicb.2021.748611.

36. Carroll, L.M., Cheng, R.A., Wiedmann, M., and Kovac, J. (2021). Keeping up with the Bacillus cereus group: taxonomy through the genomics era and beyond. Crit Rev Food Sci Nutr, 1-26. 10.1080/10408398.2021.1916735.

37. Cohn, A.R., Orsi, R.H., Carroll, L.M., Chen, R., Wiedmann, M., and Cheng, R.A. (2021). Characterization of Basal Transcriptomes Identifies Potential Metabolic and Virulence-Associated Adaptations Among Diverse Nontyphoidal Salmonella enterica Serovars. Front Microbiol 12, 730411. 10.3389/fmicb.2021.730411.

38. Kipper, D., Orsi, R.H., Carroll, L.M., Mascitti, A.K., Streck, A.F., Fonseca, A.S.K., Ikuta, N., Tondo, E.C., Wiedmann, M., and Lunge, V.R. (2021). Recent Evolution and Genomic Profile of Salmonella enterica Serovar Heidelberg Isolates from Poultry Flocks in Brazil. Appl Environ Microbiol 87, e0103621. 10.1128/AEM.01036-21.

39. Ma, Y., Chen, J., Fong, K., Nadya, S., Allen, K., Laing, C., Ziebell, K., Topp, E., Carroll, L.M., Wiedmann, M., et al. (2021). Antibiotic Resistance in Shiga Toxigenic Escherichia coli Isolates from Surface Waters and Sediments in a Mixed Use Urban Agricultural Landscape. Antibiotics (Basel) 10. 10.3390/antibiotics10030237.

40. Dai Y, Pinedo V, Tang AY, Cava F, Geisinger E. A New Class of Cell Wall-Recycling l,d-Carboxypeptidase Determines β-Lactam Susceptibility and Morphogenesis in Acinetobacter baumannii. mBio. 2021 Dec 21;12(6):e0278621.

41. Simpson BW, Nieckarz M, Pinedo V, McLean AB, Cava F, Trent MS. Acinetobacter baumannii Can Survive with an Outer Membrane Lacking Lipooligosaccharide Due to Structural Support from Elongasome Peptidoglycan Synthesis. mBio. 2021 Dec 21;12(6):e0309921.

42. Le NH, Pinedo V, Lopez J, Cava F, Feldman MF. Killing of Gram-negative and Gram-positive bacteria by a bifunctional cell wall-targeting T6SS effector. PNAS. 2021 Oct 5;118(40):e2106555118.

43. Williams MA, et al, Cava F, Brown PJB. Unipolar Peptidoglycan Synthesis in the Rhizobiales Requires an Essential Class A Penicillin-Binding Protein.   mBio. 2021 Oct 26;12(5):e0234621.

44. Campbell C, et al, Cava F, Clair G, and O'Gara J. Accumulation of Succinyl Coenzyme A Perturbs the Methicillin-Resistant Staphylococcus aureus (MRSA) Succinylome and Is Associated with Increased Susceptibility to Beta-Lactam Antibiotics. mBio 2021. Jun 29;12(3):e0053021

45. Aliashkevich A, Howell M, Brown PJB, Cava F#. A Microbial racemization of a plant-specific amino acid affects peptidoglycan structure, morphogenesis and fitness in Rhizobiales. Environmental Microbiology. 2021 Apr 8.

46. Murphy S, Murtha A, Zhao Z, Alvarez L, Diebold P, Shin JH, VanNieuwenhze M, Cava F, Doerr T. Class A Penicillin-Binding Protein-mediated cell wall synthesis promotes structural integrity during peptidoglycan endopeptidase insufficiency. mBio 2021 Apr 6;12(2):e03596-20.

47. Wang J, Alvarez L, Bulgheresi S, Cava F and den Blaauwen T. PBP4 Is Likely Involved in Cell Division of the Longitudinally Dividing Bacterium Candidatus Thiosymbion Oneisti. Antibiotics (Basel). 2021 Mar 9;10(3):274.

48. Rivera SL, Espaillat A, Aditham AK, Shieh P, Muriel-Mundo C, Kim J, Cava F#, Siegrist MS#. Bacterial Peptidoglycan Stapling with Functionalized D-Amino Acids. Cell Chemical Biology. 2021 Feb 18;28(2):213-220.e4.

49. del Peso Santos T, Alvarez L, Sit B, Irazoki O, Blake J, Warner BR, Warr AR, Bala A, Benes V, Waldor MK, Fredrick K, Cava F#. BipA exerts temperature-dependent control of biofilm-associated colony morphology in Vibrio cholerae. Elife. 2021 Feb 12;10:e60607.

50. Espaillat A, Carrasco-López C, Bernardo-Garcia N, Rojas-Altuve A, Klett J, Morreale A, Hermoso JA, Cava F#. Binding of non-canonical peptidoglycan controls Vibrio cholerae broad spectrum racemase activity. 2021 Comput Struct Biotechnol J. 2021 Jan 26;19:1119-1126.

51. Aliashkevich A and Cava F#. L,D-transpeptidases: the great unknown among the peptidoglycan crosslinkers. The FEBS Journal 2021 Jun 10. doi: 10.1111/febs.16066

52. Alvarez L, Hernandez SB and Cava F#. The cell wall of Vibrio cholerae. Annual Reviews in Microbiology 2021 Oct 8;75:151-174.

53. Gilmore MC, Ritzl-Rinkenberger B, Cava F#. An updated toolkit for exploring bacterial cell wall structure and dynamics. Fac Rev. 2021 Feb 10;10:14.

54. Hernández SB, Cava F#. New approaches and techniques for bacterial cell wall analysis. Current Opinion in Microbiology. 2021. Feb 22;60:88-95.

55. Sundin C., Saleeb M., Spjut S., Qin L., and Elofsson M. (2021) Identification of small molecules blocking the Pseudomonas aeruginosa type III secretion system protein PcrV. Biomolecules 11, 55.

56. El-Schich Z., Zhang Y., Göransson T., Dizeyi N., Persson J. L., Johansson E., Caraballo R., Elofsson M., Shinde  S., Sellergren B., and Gjörloff Wingren B. (2021) Sialic acid as a biomarker studied in breast cancer cell lines in vitro using fluorescent molecularly imprinted polymers. Applied Sciences 11, 3256.

57. Johansson E., Caraballo R., and Elofsson M. (2021) Synthesis of 4-O-alkylated N-acetylneuraminic acid derivatives. Journal of Organic Chemistry 86, 9145-9154.

58. Johansson E., Caraballo R., Hurdiss D. L., Mistry N., Andersson C. D., Thompson R. F., Ranson N. A., Zocher G., Stehle T., Arnberg N., Elofsson M. (2021) Exploring the effect of structure-based scaffold hopping on the inhibition of coxsackievirus A24v transduction by pentavalent N-acetylneuraminic acid conjugates. International Journal of Molecular Sciences 22, 8414, 1-17.

59. Gwon YD, I Nagaev, SA Nematollahi Mahani, L Mincheva-Nilsson, M Evander (2021). Cytokine profiling of human trophoblast cell lines after infection with pathogenic and live-attenuated Rift Valley fever virus. Viruses 13, 2265. 10.3390/v13112265

60.  Meheretu Y, Å Granberg, G Berhane, H Khalil, OW Lwande, M Mitiku, K Welegerima, J Goüy de Bellocq, J Bryja, H Abreha, H Leirs, F Ecke, M Evander (2021). Prevalence of orthohantavirus-reactive antibodies in humans and peri-domestic rodents in Northern Ethiopia. Viruses 13, 1054. 10.3390/v13061054.

61. Fonseca-Rodriguez O, Fors Connolly AM, Katsoularis I, Lindmark K, Farrington P. Avoiding bias in self-controlled case series studies of COVID-19. Statistics in Medicine, 2021. DOI: 10.1002/sim.9179.

62. Katsoularis I, Fonseca-Rodriguez O, Farrington P, Lindmark K, Fors Connolly AM*. Risk of acute myocardial infarction and ischaemic stroke following COVID-19 in Sweden: A self-controlled cases and matched cohort study. Lancet (2021) 398:599-607. DOI: 10.1016/S0140-6736(21)00896-5.

63. Gustafsson P, San Sebastián M, Fonseca-Rodríguez O, Fors Connolly AM. Inequitable impact of infection: Social gradients in severe COVID-19 outcomes among all confirmed SARS-CoV-2 cases during the first pandemic wave in Sweden. J Epidemiol Community Health (2021) 0:1-7. DOI: 10.1136/jech-2021-216778.

64. Fonseca-Rodriguez O, Gustafsson P, San Sebastían M, Fors Connolly AM. Spatial clustering and contextual factors associated with hospitalization and deaths due to COVID-19 in Sweden: a geospatial nationwide ecological study. BMJ Global Health (2021) 6:e006247. DOI: 10.1136/bmjgh-2021-006247

65. Holm K, Lundgren MN, Kjeldsen-Kragh J, Ljungquist O, Böttiger B, Wikén C, Öberg J, Fernström N, Rosendal E, Överby AK, Wigren Byström J, Forsell M, Landin-Olsson M, Rasmussen M. Convalescence plasma treatment of COVID-19: results from a prematurely terminated randomized controlled open-label study in Southern Sweden. BMC Res Notes. 2021 Dec 4;14(1):440. doi: 10.1186/s13104-021-05847-7. PMID: 34863304; PMCID: PMC8642769.

66. Carrasco A, Sjölander I, Van Acker A, Dernstedt A, Fehrm J, Forsell M, Friberg D, Mjösberg J, Rao A. The Tonsil Lymphocyte Landscape in Pediatric Tonsil Hyperplasia and Obstructive Sleep Apnea. Front Immunol. 2021 Oct 22;12:674080. doi: 10.3389/fimmu.2021.674080. PMID: 34745084; PMCID: PMC8570126.

67. Cagigi A, Yu M, Österberg B, Svensson J, Falck-Jones S, Vangeti S, Åhlberg E, Azizmohammadi L, Warnqvist A, Falck-Jones R, Gubisch PC, Ödemis M, Ghafoor F, Eisele M, Lenart K, Bell M, Johansson N, Albert J, Sälde J, Pettie DD, Murphy MP, Carter L, King NP, Ols S, Normark J, Ahlm C, Forsell MN, Färnert A, Loré K, Smed-Sörensen A. Airway antibodies emerge according to COVID-19 severity and wane rapidly but reappear after SARS-CoV-2 vaccination. JCI Insight. 2021 Nov 22;6(22):e151463. doi: 10.1172/jci.insight.151463. PMID: 34665783; PMCID: PMC8663786.

68.  Kerkman PF, Dernstedt A, Tadala L, Mittler E, Dannborg M, Sundling C, Maleki KT, Tauriainen J, Tuiskunen-Bäck A, Wigren Byström J, Ocaya P, Thunberg T, Jangra RK, Román-Sosa G, Guardado-Calvo P, Rey FA, Klingström J, Chandran K, Puhar A, Ahlm C, Forsell MN. Generation of plasma cells and CD27- IgD- B cells during hantavirus infection is associated with distinct pathological findings. Clin Transl Immunology. 2021 Jul 12;10(7):e1313. doi: 10.1002/cti2.1313. PMID: 34277007; PMCID: PMC8275445.

69. Normark J, Vikström L, Gwon YD, Persson IL, Edin A, Björsell T, Dernstedt A, Christ W, Tevell S, Evander M, Klingström J, Ahlm C, Forsell M. Heterologous ChAdOx1 nCoV-19 and mRNA-1273 Vaccination. N Engl J Med. 2021 Sep 9;385(11):1049-1051. doi: 10.1056/NEJMc2110716. Epub 2021 Jul 14. PMID: 34260850; PMCID: PMC8314734.

70. Lagerqvist N, Maleki KT, Verner-Carlsson J, Olausson M, Dillner J, WigrenByström J, Monsen T, Forsell M, Eriksson J, Bogdanovic G, Muschiol S, Ljunggren J, Repo J, Kjerstadius T, Muradrasoli S, Brytting M, Szekely Björndal Å, Åkerlund T, Nilsson C, Klingström J. Evaluation of 11 SARS-CoV-2 antibody tests by   using samples from patients with defined IgG antibody titers. Sci Rep. 2021 Apr 7;11(1):7614. doi: 10.1038/s41598-021-87289-6. PMID: 33828214; PMCID: PMC8027209.

71. Dernstedt A, Leidig J, Holm A, Kerkman PF, Mjösberg J, Ahlm C, Henriksson J, Hultdin M, Forsell MNE. Regulation of Decay Accelerating Factor Primes Human Germinal Center B Cells for Phagocytosis. Front Immunol. 2021 Jan 5;11:599647. doi: 10.3389/fimmu.2020.599647. PMID: 33469456; PMCID: PMC7813799.

72. Fei, K., Yan, H., Zeng, X., Huang, S., Tang, W., *Francis, M.S., *Chen, S., and *Hu, Y. (2021). LcrQ coordinates with the YopD-LcrH complex to repress lcrF expression and control type III secretion by Yersinia pseudotuberculosis. mBio. 12(3), e0145721. 10.1128/mBio.01457-21. *shared last author

73. Negeri, A.A., Mamo, H., Gurung, J.M., Firoj Mahmud, A.K.M., Fällman, M., Seyoum, E.T., Desta, A.F., and Francis, M.S. (2021). Antimicrobial resistance profiling and molecular epidemiological analysis of extended spectrum β-lactamases produced by extraintestinal invasive Escherichia coli isolates from Ethiopia: the presence of international high-risk clones ST131 and ST410 revealed. Frontiers in Microbiology. 12, 706846. 10.3389/fmicb.2021.706846.

74. Fei, K., Chao, H.J., Hu, Y., *Francis, M.S., and *Chen, S. (2021). CpxR regulates the Rcs phosphorelay system in controlling the Ysc-Yop type III secretion system in Yersinia pseudotuberculosis. Microbiology-SGM. 167(1). 10.1099/mic.0.000998. (* shared last and corresponding authors)

75. Martin, O.C.B., Bergonzini, A., Lopez Chiloeches, M., Paparouna, E., Butter, D., Theodorou, S.D.P., Haykal, M.M., Boutet-Robinet, E., Tebaldi, T., Wakeham, A., et al. (2021). Influence of the microenvironment on modulation of the host response by typhoid toxin. Cell Rep 35, 108931. 10.1016/j.celrep.2021.108931

76. Mathiasen, S.L., Gall-Mas, L., Pateras, I.S., Theodorou, S.D.P., Namini, M.R.J., Hansen, M.B., Martin, O.C.B., Vadivel, C.K., Ntostoglou, K., Butter, D., et al. (2021). Bacterial genotoxins induce T cell senescence. Cell Reports 35. ARTN 109220. 10.1016/j.celrep.2021.109220.

77. Chiloeches, M.L., Bergonzini, A., Frisan, T., and Martin, O.C.B. (2021b). Characterization of macrophage infiltration and polarization by double fluorescence immunostaining in mouse colonic mucosa. STAR Protoc 2, 100833. 10.1016/j.xpro.2021.100833

78. Boutet-Robinet, E., Haykal, M.M., Hashim, S., Frisan, T., and Martin, O.C.B. (2021). Detection of DNA damage by alkaline comet assay in mouse colonic mucosa. STAR Protoc 2, 100872. 10.1016/j.xpro.2021.100872

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164. Obanda, V., Otieno, V.A., Kingori, E.M., Ndeereh, D., Lwande, O.W. and Chiyo, P.I. (2021). Identifying Edaphic Factors and Normalized Difference Vegetation Index Metrics Driving Wildlife Mortality from Anthrax in Kenya’s Wildlife Areas. Frontiers in Ecology and Evolution, 9, p.939.

165. Blanco-Penedo, I., Obanda, V., Kingori, E., Agwanda, B., Ahlm, C. and Lwande, O.W. (2021). Seroepidemiology of Crimean-Congo Hemorrhagic Fever Virus (CCHFV) in cattle across three livestock Pastoral regions in Kenya. Dairy, 2(3), pp.425-434.

166. Näslund, J., Ahlm, C., Islam, K., Evander, M., Bucht, G. and Lwande, O.W. (2021). Emerging mosquito-borne viruses linked to Aedes aegypti and Aedes albopictus: global status and preventive strategies. Vector-Borne and Zoonotic Diseases, 21(10), pp.731-746.

167. Obanda, V., Agwanda, B., Blanco-Penedo, I., Mwangi, I.A., King'ori, E., Omondi, G.P., Ahlm, C., Evander, M. and Lwande, O.W. (2021). Livestock presence influences the seroprevalence of Crimean Congo hemorrhagic fever virus on sympatric wildlife in Kenya. Vector-Borne and Zoonotic Diseases, 21(10), pp.809-816.

168. Jürgens, K., and Wikner, J. (2021). Microbial community and processes. In In Climate Change in the Baltic Sea: 2021 Fact Sheet, J. Haldin, P. Kääriä, H.E.M. Meier, and J. Pålsson, eds. (Helsinki Commission), pp. p. 38.

169. Ojeda-May, P., Mushtaq, A.U., Rogne , P,. Verma, A., Ovchinnikov, V., Grundström, C., Dulko-Smith, B., Sauer, U.H., Wolf-Watz, M*., & Nam K, (2021).  Dynamic Connection between Enzymatic Catalysis and Collective Protein Motions.  Biochemistry, 60, 2246-2258. * = shared corresponding author

170. Phoeurk C., Mushtaq A.U., Rogne P., & Wolf-Watz M.  (2021).  Milligram scale expression, refolding, and purification of Bombyx mori cocoonase using a recombinant E. coli system. Protein Expression and Purification, 186, 105919. DOI: 10.1016

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176. Carnero Corrales, M.A., Zinken, S., Konstantinidis, G., Rafehi, M., Abdelrahman, A., Wu, Y.W., Janning, P., Muller, C.E., Laraia, L., and Waldmann, H. (2021). Thermal proteome profiling identifies the membrane-bound purinergic receptor P2X4 as a target of the autophagy inhibitor indophagolin. Cell Chem Biol 28, 1750-1757 e1755. 10.1016/j.chembiol.2021.02.017.

177. Welén K, Rosendal E, Gisslén M, Lenman A, Freyhult E, Fonseca-Rodríguez O, Bremell D, Stranne J, Balkhed ÅÖ, Niward K, Repo J, Robinsson D, Henningsson AJ, Styrke J, Angelin M, Lindquist E, Allard A, Becker M, Rudolfsson S, Buckland R, Carlsson CT, Bjartell A, Nilsson AC, Ahlm C, Connolly AF**, Överby AK**, Josefsson A**. A Phase 2 Trial of the Effect of Antiandrogen Therapy on COVID-19 Outcome: No Evidence of Benefit, Supported by Epidemiology and In Vitro Data. European Urology 2021 Dec 15:S0302-2838(21)02224-7. doi: 10.1016/j.eururo.2021.12.013. Online ahead of print. (** contributed equally)IF: 20,096

178. Kruse T, Benz C, Garvanska DH, Lindqvist R, Mihalic F, Coscia F, Inturi R, Sayadi A, Simonetti L, Nilsson E, Ali M, Kliche J, Moliner Morro A, Mund A, Andersson E, McInerney G, Mann M, Jemth P, Davey NE, Överby AK*, Nilsson J*, Ivarsson Y*. Large scale discovery of coronavirus-host factor protein interaction motifs reveals SARS-CoV-2 specific mechanisms and vulnerabilities. Nat Commun. 2021 Nov 19;12(1):6761. doi: 10.1038/s41467-021-26498-z. PMID: 34799561 (* Equal contributor and corresponding authors)

179. Welén K, Överby AK, Ahlm C, Freyhult E, Robinsson D, Henningsson AJ, Stranne J, Bremell D, Angelin M, Lindquist E, Buckland R, Carlsson CT, Pauksens K, Bill-Axelsson A, Akre O, Ryden C, Wagenius M, Bjartell A, Nilsson AC, Styrke J, Repo J, Balkhed ÅÖ, Niward K, Gisslén M, Josefsson A. COVIDENZA - A prospective, multicenter, randomized PHASE II clinical trial of enzalutamide treatment to decrease the morbidity in patients with Corona virus disease 2019 (COVID-19): a structured summary of a study protocol for a randomised controlled trial. Trials. 2021 Mar 16;22(1):209. doi: 10.1186/s13063-021-05137-4.

180. Reimer L, Betzer C, Kofoed RH, Volbracht C, Fog K, Kurhade C, Nilsson E, Överby AK, Jensen PH. PKR kinase directly regulates tau expression and Alzheimer’s Disease-related tau phosphorylation. Brain Pathology, 2021, 31 (1), 103-119 doi: 10.1111/bpa.12883. Online ahead of print. IF:6.624

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185. Zapatero-Belinchón, F.J., Moeller, R., Lasswitz, L., van Ham, M., Becker, M., Brogden, G., Rosendal, E., Bi, W., Carriquí-Madroñal, B., Islam, K., Lenman, A., Gunesch, A.P., Kirui, J., Pietschmann, T., Överby, A.K., Jänsch, L., Gerold, G. (2021) Fluvastatin mitigates SARS-CoV-2 infection in human lung cells. iScience. 24(12):103469. 10.1016/j.isci.2021.103469. 8. Zapatero-Belinchón, F.J., Carriquí-Madroñal, B., Gerold, G. (2021) Proximity labeling approaches to study protein complexes during virus infection. Adv Virus Res. 109:63-104. 10.1016/bs.aivir.2021.02.001.

186. Krüger, N., Rocha, C., Runft, S., Krüger, J., Färber, I., Armando, F., Leitzen, E., Brogden, G., Gerold, G., Pöhlmann, S., Hoffmann, M., Baumgärtner, W. (2021) The Upper Respiratory Tract of Felids Is Highly Susceptible to SARS-CoV-2 Infection. Int J Mol Sci. 22(19):10636. 10.3390/ijms221910636.

187. Kirui, J., Abidine, Y., Lenman, A., Islam, K., Gwon, Y.D., Lasswitz, L., Evander, M., Bally, M., Gerold, G. (2021) The Phosphatidylserine Receptor TIM-1 Enhances Authentic Chikungunya Virus Cell Entry. Cells. 10(7):1828. 10.3390/cells10071828.

188. Ricke-Hoch, M., Stelling, E., Lasswitz, L., Gunesch, A.P., Kasten, M., Zapatero-Belinchón, F.J., Brogden, G., Gerold, G., Pietschmann, T., Montiel, V., Balligand, J.L., Facciotti, F., Hirsch, E., Gausepohl, T., Elbahesh, H., Rimmelzwaan, G.F., Höfer, A., Kühnel, M.P., Jonigk, D., Eigendorf, J., Tegtbur, U., Mink, L., Scherr, M., Illig, T., Schambach, A., Pfeffer, T.J., Hilfiker, A., Haverich, A., Hilfiker-Kleiner, D. (2021) Impaired immune response mediated by prostaglandin E2 promotes severe COVID-19 disease. PLoS One. 16(8):e0255335. 10.1371/journal.pone.0255335.

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Publikationer 2020

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Publikationer 2019

saknas

 

Publikationer 2018

Abbara A, Rawson TM, Karah N, El-Amin W, Hatcher J, Tajaldin B, Dar O, Dewachi O, Abu Sitta G, Uhlin BE, Sparrow A (2018) Antimicrobial resistance in the context of the Syrian conflict: Drivers before and after the onset of conflict and key recommendations. Int J Infect Dis 73: 1-6

Abbara A, Rawson TM, Karah N, El-Amin W, Hatcher J, Tajaldin B, Dar O, Dewachi O, Abu Sitta G, Uhlin BE, Sparrow A (2018) A summary and appraisal of existing evidence of antimicrobial resistance in the Syrian conflict. Int J Infect Dis 75: 26-33

Alam A, Golovliov I, Javed E, Sjöstedt A (2018) ClpB mutants of Francisella tularensis subspecies holarctica and tularensis are defective for type VI secretion and intracellular replication. Sci Rep 8: 11324

Aliashkevich A, Alvarez L, Cava F (2018) New Insights Into the Mechanisms and Biological Roles of D-Amino Acids in Complex Eco-Systems. Front Microbiol 9: 683

Alvarez L, Aliashkevich A, de Pedro MA, Cava F (2018) Bacterial secretion of D-arginine controls environmental microbial biodiversity. Isme J 12: 438-450

Askarian F, Lapek JD, Jr., Dongre M, Tsai CM, Kumaraswamy M, Kousha A, Valderrama JA, Ludviksen JA, Cavanagh JP, Uchiyama S, Mollnes TE, Gonzalez DJ, Wai SN, Nizet V, Johannessen M (2018) Staphylococcus aureus Membrane-Derived Vesicles Promote Bacterial Virulence and Confer Protective Immunity in Murine Infection Models. Front Microbiol 9: 262

Azpiazu PM, Schou M, Eriksson A, Elmore C, Almqvist F, Varrone A (2018) Testing The Feasibility of a Dihidro Thiazolo Ring-fused 2-pyridone Derivative As a Possible PET Ligand to Target Alpha-synuclein in Neurogenerative Disorders. Eur J Nucl Med Mol Imaging 45: S646-S647

Bacal J, Moriel-Carretero M, Pardo B, Barthe A, Sharma S, Chabes A, Lengronne A, Pasero P (2018) Mrc1 and Rad9 cooperate to regulate initiation and elongation of DNA replication in response to DNA damage. Embo Journal 37: 18

Baggen J, Hurdiss DL, Zocher G, Mistry N, Robert RW, Slager JJ, Guo HB, van Vliet ALW, Wahedi M, Benschop K, Duizer E, de Haan CAM, de Vries E, Casasnovas JM, de Groot RJ, Arnberg N, Stehle T, Ranson NA, Thibaut HJ, van Kuppeveld FJM (2018). Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus. Proceedings of the National Academy of Sciences of the United States of America 115: 397-402

Bamyaci S, Ekestubbe S, Nordfelth R, Erttmann SF, Edgren T, Forsberg Å (2018) YopN Is Required for Efficient Effector Translocation and Virulence in Yersinia pseudotuberculosis. Infect Immun 86

Bergström S, Normark J (2018) Microbiological features distinguishing Lyme disease and relapsing fever spirochetes. Wien Klin Wochen 130: 484-490

Birdsell DN, Ozsurekci Y, Rawat A, Aycan AE, Mitchell CL, Sahl JW, Johansson A, Colman RE, Schupp JM, Ceyhan M, Keim PS, Wagner DM (2018) Coinfections identified from metagenomic analysis of cervical lymph nodes from tularemia patients. BMC Infect Dis 18: 319

Bjarnsholt T, Buhlin K, Dufrene YF, Gomelsky M, Moroni A, Ramstedt M, Rumbaugh KP, Schulte T, Sun L, Akerlund B, Romling U (2018) Biofilm formation - what we can learn from recent developments. Journal of Internal Medicine 284: 332-345

Bowman LR, Rocklöv J, Kroeger A, Olliaro P, Skewes R (2018) A comparison of Zika and dengue outbreaks using national surveillance data in the Dominican Republic. Plos Neglect Trop Dis 12: 13

Brännström K, Gharibyan AL, Islam T, Iakovleva I, Nilsson L, Lee CC, Sandblad L, Pamren A, Olofsson A (2018) Scanning electron microscopy as a tool for evaluating morphology of amyloid structures formed on surface plasmon resonance chips. Data in Brief 19: 1166-1170

Brännström K, Islam T, Gharibyan AL, Lakovleva I, Nilsson L, Lee CC, Sandblad L, Pamren A, Olofsson A (2018) The Properties of Amyloid-beta Fibrils Are Determined by their Path of Formation. Journal of Molecular Biology 430: 1940-1949

Brodiazhenko T, Johansson MJO, Takada H, Nissan T, Hauryliuk V, Murina V (2018) Elimination of Ribosome Inactivating Factors Improves the Efficiency of Bacillus subtilis and Saccharomyces cerevisiae Cell-Free Translation Systems. Frontiers in Microbiology 9: 8

Broglia L, Materne S, Lecrivain AL, Hahnke K, Le Rhun A, Charpentier E (2018) RNase Y-mediated regulation of the streptococcal pyrogenic exotoxin B. Rna Biology 15: 1336-1347

Bueno E, Sit B, Waldor MK, Cava F (2018) Anaerobic nitrate reduction divergently governs population expansion of the enteropathogen Vibrio cholerae. Nat Microbiol 3: 1346-1353

Bystrom JW, Naslund J, Trulsson F, Evander M, Lwande OW, Ahlm C, Bucht G (2018) Quantification and kinetics of viral RNA transcripts produced in Orthohantavirus infected cells. Virology Journal 15: 18

Cairns AG, Vazquez-Romero A, Moein MM, Aden J, Elmore CS, Takano A, Arakawa R, Varrone A, Almqvist F, Schou M (2018) Increased Brain Exposure of an Alpha-Synuclein Fibrillization Modulator by Utilization of an Activated Ester Prodrug Strategy. ACS Chem Neurosci 9: 2542-2547

Carcamo JRP, Morell ML, Vazquez CA, Vatansever S, Upadhyay AS, Överby AK, Cordo SM, Garcia CC (2018) The interplay between viperin antiviral activity, lipid droplets and Junin mammarenavirus multiplication. Virology 514: 216-229

Chahlafi Z, Alvarez L, Cava F, Berenguer J (2018) The role of conserved proteins DrpA and DrpB in nitrate respiration of Thermus thermophilus. Environmental Microbiology 20: 3851-3861

Charpentier E (2018) Spotlight on... Emmanuelle Charpentier. FEMS Microbiol Lett 365: fnx271

Codemo M, Muschiol S, Iovino F, Nannapaneni P, Plant L, Wai SN, Henriques-Normark B (2018) Immunomodulatory Effects of Pneumococcal Extracellular Vesicles on Cellular and Humoral Host Defenses. MBio 9: e00559-18

Coquel F, Silva MJ, Techer H, Zadorozhny K, Sharma S, Nieminuszczy J, Mettling C, Dardillac E, Barthe A, Schmitz AL, Promonet A, Cribier A, Sarrazin A, Niedzwiedz W, Lopez B, Costanzo V, Krejci L, Chabes A, Benkirane M, Lin YL et al. (2018) SAMHD1 acts at stalled replication forks to prevent interferon induction. Nature 557: 57-+

Crawford AC, Lehtovirta-Morley LE, Alamir O, Niemiec MJ, Alawfi B, Alsarraf M, Skrahina V, Costa ACBP, Anderson A, Yellagunda S, Ballou ER, Hube B, Urban CF, Wilson D (2018) Biphasic zinc compartmentalisation in a human fungal pathogen. Plos Pathogens 14

Crowe-McAuliffe C, Graf M, Huter P, Takada H, Abdelshahid M, Novacek J, Murina V, Atkinson GC, Hauryliuk V, Wilson DN (2018) Structural basis for antibiotic resistance mediated by the Bacillus subtilis ABCF ATPase VmlR. Proceedings of the National Academy of Sciences of the United States of America 115: 8978-8983

Dahlberg T, Stangner T, Zhang HQ, Wiklund K, Lundberg P, Edman L, Andersson M (2018) 3D printed water-soluble scaffolds for rapid production of PDMS micro-fluidic flow chambers. Scientific Reports 8

Dongre M, Singh B, Aung KM, Larsson P, Miftakhova R, Persson K, Askarian F, Johannessen M, von Hofsten J, Persson JL, Erhardt M, Tuck S, Uhlin BE, Wai SN (2018) Flagella-mediated secretion of a novel. Commun Biol 1: 59

Dingeldein APG, Sparrman T, Gröbner G (2018) Oxidatively stressed mitochondria-mimicking membranes: A molecular insight into their organization during apoptosis. Biochimica Et Biophysica Acta-Biomembranes 1860: 2644-2654

Duffy MR, Alonso-Padilla J, John L, Chandra N, Khan S, Ballmann MZ, Lipiec A, Heemskerk E, Custers J, Arnberg N, Havenga M, Baker AH, Lemckert A (2018) Generation and characterization of a novel candidate gene therapy and vaccination vector based on human species D adenovirus type 56. Journal of General Virology 99: 135-147

Egondi T, Ettarh R, Kyobutungi C, Ng N, Rocklov J (2018) Exposure to Outdoor Particles (PM2.5) and Associated Child Morbidity and Mortality in Socially Deprived Neighborhoods of Nairobi, Kenya. Atmosphere 9: 12

Ekblad T, Verheugd P, Lindgren AE, Nyman T, Elofsson M, Schuler H (2018) Identification of Poly(ADP-Ribose) Polymerase Macrodomain Inhibitors Using an AlphaScreen Protocol. SLAS Discov 23: 353-362

Eneslatt K, Golovliov I, Ryden P, Sjöstedt A (2018) Vaccine-Mediated Mechanisms Controlling Replication of Francisella tularensis in Human Peripheral Blood Mononuclear Cells Using a Co-culture System. Front Cell Infect Microbiol 8: 27

Enevold J, Larsen C, Zakrisson J, Andersson M, Edman L (2018) Realizing Large-Area Arrays of Semiconducting Fullerene Nanostructures with Direct Laser Interference Patterning. Nano Lett 18: 540-545

Flahou B, Rossi M, Bakker J, Langermans JAM, Heuvelman E, Solnick JV, Martin ME, O'Rourke J, Ngoan LD, Hoa NX, Nakamura M, Överby AK, Matsui H, Ota H, Matsumoto T, Foss DL, Kopta LA, Omotosho O, Franciosini MP, Proietti PC et al. (2018) Evidence for a primate origin of zoonotic Helicobacter suis colonizing domesticated pigs. Isme J 12: 77-86

Goormaghtigh F, Fraikin N, Putrins M, Hallaert T, Hauryliuk V, Garcia-Pino A, Sjodin A, Kasvandik S, Udekwu K, Tenson T, Kaldalu N, Van Melderen L (2018) Reassessing the Role of Type II Toxin-Antitoxin Systems in Formation of Escherichia coli Type II Persister Cells. Mbio 9: 14

Goormaghtigh F, Fraikin N, Putrins M, Hauryliuk V, Garcia-Pino A, Udekwu K, Tenson T, Kaldalu N, Van Melderen L (2018) Reply to Holden and Errington, "Type II Toxin-Antitoxin Systems and Persister Cells". Mbio 9: 2

Gurung JM, Amer AAA, Francis MK, Costa TRD, Chen S, Zavialov AV, Francis MS (2018) Heterologous Complementation Studies With the YscX and YscY Protein Families Reveals a Specificity for Yersinia pseudotuberculosis Type III Secretion. Front Cell Infect Microbiol 8: 80

Gylfe A, Ribers A, Forsman O, Bucht G, Alenius GM, Wallberg-Jonsson S, Ahlm C, Evander M (2018) Mosquitoborne Sindbis Virus Infection and Long-Term Illness. Emerging Infectious Diseases 24: 1141-1142

Hakobyan S, Rzhepishevska O, Barbero DR, Ramstedt M (2018). Functionalization of zwitterionic polymer brushes, do they remain antifouling? Surf Interface Anal 50: 1001-1006

Hall M, Hasegawa Y, Yoshimura F, Persson K (2018) Structural and functional characterization of shaft, anchor, and tip proteins of the Mfa1 fimbria from the periodontal pathogen Porphyromonas gingivalis. Scientific Reports 8: 15

Hausmaninger T, Zhao G, Ma WG, Axner O (2018) Depletion of the vibrational ground state of CH4 in absorption spectroscopy at 3.4 mu m in N-2 and air in the 1-100Torr range. Journal of Quantitative Spectroscopy & Radiative Transfer 205: 59-70

Hille F, Richter H, Wong SP, Bratovic M, Ressel S, Charpentier E (2018) The Biology of CRISPR-Cas: Backward and Forward. Cell 172: 1239-1259

Hoffman T, Lindeborg M, Barboutis C, Erciyas-Yavuz K, Evander M, Fransson T, Figuerola J, Jaenson TGT, Kiat Y, Lindgren PE, Lundkvist A, Mohamed N, Moutailler S, Nystrom F, Olsen B, Salaneck E (2018) Alkhurma Hemorrhagic Fever Virus RNA in Hyalomma rufipes Ticks Infesting Migratory Birds, Europe and Asia Minor. Emerging Infectious Diseases 24: 879-882

Hussain-Alkhateeb L, Kroeger A, Olliaro P, Rocklov J, Sewe MO, Tejeda G, Benitez D, Gill B, Hakim SL, Gomes Carvalho R, Bowman L, Petzold M (2018) Early warning and response system (EWARS) for dengue outbreaks: Recent advancements towards widespread applications in critical settings. PLoS One 13: e0196811

Ianevski A, Zusinaite E, Kuivanen S, Strand M, Lysvand H, Teppor M, Kakkola L, Paavilainen H, Laajala M, Kallio-Kokko H, Valkonen M, Kantele A, Telling K, Lutsar I, Letjuka P, Metelitsa N, Oksenych V, Bjoras M, Nordbo SA, Dumpis U, Vitkauskiene C, Öhrmalm C, Bondeson K, Bergqvist A, Aittokallio T, Cox RJ, Evander M, Hukkanen V, Marjomaki V, Julkunen I, Vapalahtit O, Tenson T, Merits A, Kainov D. (2018). Novel activities of safe-in-human broad-spectrum antiviral agents. Antiviral Research 154: 174-182

Islam MK, Strand M, Saleeb M, Svensson R, Baranczewski P, Artursson P, Wadell G, Ahlm C, Elofsson M, Evander M (2018) Anti-Rift Valley fever virus activity in vitro, pre-clinical pharmacokinetics and oral bioavailability of benzavir-2, a broad-acting antiviral compound. Sci Rep 8: 1925

Jin CS, Barone A, Borén T, Teneberg S (2018) Helicobacter pylori-binding nonacid glycosphingolipids in the human stomach. Journal of Biological Chemistry 293: 17248-17266

Johansson AC, Rutkowski L, Filipsson A, Hausmaninger T, Zhao G, Axner O, Foltynowicz A (2018) Broadband calibration-free cavity-enhanced complex refractive index spectroscopy using a frequency comb. Optics Express 26: 20633-20648

Kajan GL, Lipiec A, Bartha D, Allard A, Arnberg N (2018) A multigene typing system for human adenoviruses reveals a new genotype in a collection of Swedish clinical isolates. PLoS One 13: e0209038

Karlberg T, Hornyak P, Pinto AF, Milanova S, Ebrahimi M, Lindberg M, Pullen N, Nordstrom A, Loverli E, Caraballo R, Wong EV, Nareoja K, Thorsell AG, Elofsson M, De la Cruz EM, Bjorkegren C, Schuler H (2018) 14-3-3 proteins activate Pseudomonas exotoxins-S and -T by chaperoning a hydrophobic surface. Nature Communications 9: 11

Knutsson S, Engdahl C, Kumari R, Forsgren N, Lindsren C, Kindahl T, Kitur S, Wachira L, Kamau L, Ekstrom F, Linusson A (2018) Noncovalent Inhibitors of Mosquito Acetylcholinesterase 1 with Resistance-Breaking Potency. J Med Chem 61: 10545-10557

Kong D, Megone W, Nguyen KDQ, Di Cio S, Ramstedt M, Gautrot JE (2018) Protein Nanosheet Mechanics Controls Cell Adhesion and Expansion on Low-Viscosity Liquids. Nano Lett 18: 1946-1951

Kong ZQ, Jia SD, Chabes AL, Appelblad P, Lundmark R, Moritz T, Chabes A (2018) Simultaneous determination of ribonucleoside and deoxyribonucleoside triphosphates in biological samples by hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry. Nucleic Acids Research 46: 8

Kouidmi I, Alvarez L, Collet JF, Cava F, Paradis-Bleau C (2018) The Chaperone Activities of DsbG and Spy Restore Peptidoglycan Biosynthesis in the elyC Mutant by Preventing Envelope Protein Aggregation. Journal of Bacteriology 200: e00245-18

Krzyzanowski A, Saleeb M, Elofsson M (2018) Synthesis of Indole-, Benzo b thiophene-, and Benzo b selenophene-Based Analogues of the Resveratrol Dimers Viniferifuran and (+/-)-Dehydroampelopsin B. Organic Letters 20: 6650-6654

Kudrin P, Dzhygyr I, Ishiguro K, Beljantseva J, Maksimova E, Oliveira SRA, Varik V, Payoe R, Konevega AL, Tenson T, Suzuki T, Hauryliuk V (2018) The ribosomal A-site finger is crucial for binding and activation of the stringent factor RelA. Nucleic Acids Research 46: 1973-1983

Kulen M, Lindgren M, Hansen S, Cairns AG, Grundström C, Begum A, van der Lingen I, Brännström K, Hall M, Sauer UH, Johansson J, Sauer-Eriksson AE, Almqvist F (2018) Structure-Based Design of Inhibitors Targeting PrfA, the Master Virulence Regulator of Listeria monocytogenes. J Med Chem 61: 4165-4175

Kumar A, Saleeb M, Werz D, Elofsson M (2018) Cyclopropylmethyl Protection of Phenols: Total Synthesis of the Resveratrol Dimers Anigopreissin A and Resveratrol-Piceatannol Hybrid. ChemistryOpen 7: 953-956

Kumar K, Cava F (2018) Integrating network analysis with chromatography: introducing a novel chemometry-chromatography based analytical procedure to classify the bacterial cell wall collection. Analytical Methods 10: 1172-1180

Kumar K, Cava F (2018) Principal coordinate analysis assisted chromatographic analysis of bacterial cell wall collection: A robust classification approach. Analytical Biochemistry 550: 8-14

Kurhade C, Schreier S, Lee YP, Zegenhagen L, Hjertqvist M, Dobler G, Kroger A, Överby AK (2018) Correlation of Severity of Human Tick-Borne Encephalitis Virus Disease and Pathogenicity in Mice. Emerging Infectious Diseases 24: 1709-1712

Labuhn M, Adams FF, Ng M, Knoess S, Schambach A, Charpentier EM, Schwarzer A, Mateo JL, Klusmann JH, Heckl D (2018) Refined sgRNA efficacy prediction improves large- and small-scale CRISPR-Cas9 applications. Nucleic Acids Res 46: 1375-1385

Lanz MC, Oberly S, Sanford EJ, Sharma S, Chabes A, Smolka MB (2018) Separable roles for Mec1/ATR in genome maintenance, DNA replication, and checkpoint signaling. Genes & Development 32: 822-835

Larsson M, Fraccalvieri D, Andersson CD, Bonati L, Linusson A, Andersson PL (2018) Identification of potential aryl hydrocarbon receptor ligands by virtual screening of industrial chemicals. Environ Sci Pollut Res 25: 2436-2449

Lasswitz L, Chandra N, Arnberg N, Gerold G (2018) Glycomics and Proteomics Approaches to Investigate Early Adenovirus-Host Cell Interactions. Journal of Molecular Biology 430: 1863-1882

Lecrivain AL, Le Rhun A, Renault TT, Ahmed-Begrich R, Hahnke K, Charpentier E (2018) In vivo 3 '-to-5 ' exoribonuclease targetomes of Streptococcus pyogenes. Proceedings of the National Academy of Sciences of the United States of America 115: 11814-11819

Lee W, Bell ML, Gasparrini A, Armstrong BG, Sera F, Hwang S, Lavigne E, Zanobetti A, Coelho DZS, Saldiva PHN, Osorio S, Tobias A, Zeka A, Goodman PG, Forsberg B, Rocklöv J, Hashizume M, Honda Y, Guo YLL, Seposo X et al. (2018) Mortality burden of diurnal temperature range and its temporal changes: A multi-country study. Environ Int 110: 123-130

Lekmeechai S, Su YC, Brant M, Alvarado-Kristensson M, Vallström A, Obi I, Arnqvist A, Riesbeck K (2018) Helicobacter pylori Outer Membrane Vesicles protect the pathogen from reactive oxygen species of the respiratory burst. Frontiers in Microbiology 9: 6

Lenman A, Liaci AM, Liu Y, Frangsmyr L, Frank M, Blaum BS, Chai WG, Podgorski, II, Harrach B, Benko M, Feizi T, Stehle T, Arnberg N (2018) Polysialic acid is a cellular receptor for human adenovirus 52. Proceedings of the National Academy of Sciences of the United States of America 115: E4264-E4273

Li SQ, Xu ZY, Xu JW, Zuo LY, Yu CH, Zheng P, Gan HY, Wang XZ, Li LT, Sharma S, Chabes A, Li D, Wang S, Zheng SH, Li JB, Chen XF, Sun YJ, Xu DY, Han JH, Chan KM et al. (2018) Rtt105 functions as a chaperone for replication protein A to preserve genome stability. Embo Journal 37: 16

Lindgren C, Tyagi M, Viljanen J, Toms J, Ge CR, Zhang N, Holmdahl R, Kihlberg J, Linusson A (2018) Dynamics Determine Signaling in a Multicomponent System Associated with Rheumatoid Arthritis. J Med Chem 61: 4774-4790

Lindqvist R, Kurhade C, Gilthorpe JD, Överby AK (2018) Cell-type- and region-specific restriction of neurotropic flavivirus infection by viperin. Journal of Neuroinflammation 15: 11

Lindqvist R, Överby AK (2018) The Role of Viperin in Antiflavivirus Responses. DNA Cell Biol 37: 725-730

Lindqvist R, Upadhyay A, Överby AK (2018) Tick-Borne Flaviviruses and the Type I Interferon Response. Viruses-Basel 10: 21

Lopes JP, Stylianou M, Backman E, Holmberg S, Jass J, Claesson R, Urban CF (2018) Evasion of Immune Surveillance in Low Oxygen Environments Enhances Candida albicans Virulence. MBio 9: e02120-18

Lund H, Pieber M, Parsa R, Han JM, Grommisch D, Ewing E, Kular L, Needhamsen M, Espinosa A, Nilsson E, Överby AK, Butovsky O, Jagodic M, Zhang XM, Harris RA (2018) Competitive repopulation of an empty microglial niche yields functionally distinct subsets of microglia-like cells. Nature Communications 9: 13

Lwande OW, Naslund J, Lundmark E, Ahlm K, Ahlm C, Bucht G, Evander M (2018) Experimental Infection and Transmission Competence of Sindbis Virus in Culex torrentium and Culex pipiens Mosquitoes from Northern Sweden. Vector-Borne Zoonotic Dis 19: 128-133

Manav MC, Beljantseva J, Bojer MS, Tenson T, Ingmer H, Hauryliuk V, Brodersen DE (2018) Structural basis for (p)ppGpp synthesis by the Staphylococcus aureus small alarmone synthetase RelP. Journal of Biological Chemistry 293: 3254-3264

Massad E, Amaku M, Coutinho FAB, Struchiner CJ, Burattini MN, Khan K, Liu-Helmersson J, Rocklöv J, Kraemer MUG, Wilder-Smith A (2018) Estimating the probability of dengue virus introduction and secondary autochthonous cases in Europe. Scientific Reports 8: 12

Matiko MK, Salekwa LP, Kasanga CJ, Kimera SI, Evander M, Nyangi WP (2018) Serological evidence of inter-epizootic/interepidemic circulation of Rift Valley fever virus in domestic cattle in Kyela and Morogoro, Tanzania. Plos Neglect Trop Dis 12: e0006931

Mojica SA, Eriksson AU, Davis RA, Bahnan W, Elofsson M, Gylfe Å (2018) Red Fluorescent Chlamydia trachomatis Applied to Live Cell Imaging and Screening for Antibacterial Agents. Frontiers in Microbiology 9: 13

Mosomtai G, Evander M, Mundia C, Sandstrom P, Ahlm C, Hassan OA, Lwande OW, Gachari MK, Landmann T, Sang R (2018) Datasets for mapping pastoralist movement patterns and risk zones of Rift Valley fever occurrence. Data in Brief 16: 762-770

Mostafavi E, Ghasemi A, Rohani M, Molaeipoor L, Esmaeili S, Mohammadi Z, Mahmoudi A, Aliabadian M, Johansson A (2018) Molecular Survey of Tularemia and Plague in Small Mammals From Iran. Frontiers in Cellular and Infection Microbiology 8:215

Murina V, Kasari M, Hauryliuk V, Atkinson GC (2018) Antibiotic resistance ABCF proteins reset the peptidyl transferase centre of the ribosome to counter translational arrest. Nucleic Acids Research 46: 3753-3763

Nakamura M, Överby AK, Takakashi S, Murayama SY, Matsui H (2018) Parietal cell damage by viable Helicobacter suis could be closely related to the formation of the gastric MALT lymphoma formation in C57BL/6 Infection Model. Helicobacter 23: 1

Nakao R, Myint SL, Wai SN, Uhlin BE (2018) Enhanced Biofilm Formation and Membrane Vesicle Release by Escherichia coli Expressing a Commonly Occurring Plasmid Gene, kil. Frontiers in Microbiology 9: 18

Nasstrom E, Jonsson P, Johansson A, Dongol S, Karkey A, Basnyat B, Thieu NTV, Van TT, Thwaites GE, Antti H, Baker S (2018) Diagnostic metabolite biomarkers of chronic typhoid carriage. Plos Neglect Trop Dis 12(1): e0006215

Nilsson L, Pamren A, Islam T, Brännström K, Gochin SA, Pettersson N, Iakovieva I, Sandblad L, Gharibyan AL, Olofsson A (2018) Transthyretin Interferes with A beta Amyloid Formation by Redirecting Oligomeric Nuclei into Non-Amyloid Aggregates. Journal of Molecular Biology 430: 2722-2733

Odhiambo Sewe M, Bunker A, Ingole V, Egondi T, Oudin Astrom D, Hondula DM, Rocklöv J, Schumann B (2018) Estimated Effect of Temperature on Years of Life Lost: A Retrospective Time-Series Study of Low-, Middle-, and High-Income Regions. Environ Health Perspect 126: 017004

Omattage NS, Deng ZQ, Pinkner JS, Dodson KW, Almqvist F, Yuan P, Hultgren SJ (2018) Structural basis for usher activation and intramolecular subunit transfer in P pilus biogenesis in Escherichia coli. Nat Microbiol 3: 1362-1368

Orrego AH, Lopez-Gallego F, Espaillat A, Cava F, Guisan JM, Rocha-Martin J (2018) One‐step Synthesis of α‐Keto Acids from Racemic Amino Acids by A Versatile Immobilized Multienzyme Cell‐free System. ChemCatChem 10: 3002-3011

Panayiotou C, Lindqvist R, Kurhade C, Vonderstein K, Pasto J, Edlund K, Upadhyay AS, Överby AK (2018) Viperin Restricts Zika Virus and Tick-Borne Encephalitis Virus Replication by Targeting NS3 for Proteasomal Degradation. Journal of Virology 92: 13

Panda S, Gekara NO (2018) The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex. Nature Communications 9: 13

Paulsen MH, Karlsen EA, Ausbacher D, Anderssen T, Bayer A, Ochtrop P, Hedberg C, Haug T, Sollid JUE, Strom MB (2018) An amphipathic cyclic tetrapeptide scaffold containing halogenated (2,2)-amino acids with activity against multiresistant bacteria. Journal of Peptide Science 24: 11

Paulsson M, Che KF, Ahi J, Tham J, Sandblad L, Smith ME, Qvarfordt I, Su Y-C, Linden A, Riesbeck K (2018) Bacterial Outer Membrane Vesicles Induce Vitronectin Release Into the Bronchoalveolar Space Conferring Protection From Complement-Mediated Killing. Frontiers in Microbiology 9: 1559

Peng XP, Lim S, Li SB, Marjavaara L, Chabes A, Zhao XL (2018) Acute Smc5/6 depletion reveals its primary role in rDNA replication by restraining recombination at fork pausing sites. PLoS genetics 14: 20

Quereda JJ, Andersson C, Cossart P, Johansson J, Pizarro-Cerda J (2018) Role in virulence of phospholipases, listeriolysin O and listeriolysin S from epidemic Listeria monocytogenes using the chicken embryo infection model. Vet Res 49: 13

Rajan A, Persson BD, Frangsmyr L, Olofsson A, Sandblad L, Heino J, Takada Y, Mould AP, Schnapp LM, Gall J, Arnberg N (2018) Enteric Species F Human Adenoviruses use Laminin-Binding Integrins as Co-Receptors for Infection of Ht-29 Cells. Scientific Reports 8: 14

Ramstedt M (2018) Brushes and microorganisms. In Polymer och Biopolymer Brushes: Fundamentals and Applications in Materials Science and Biotechnology, Azzaroni O, Szleifer I (eds) pp 579-620. Hoboken NJ, USA: John Wiley & Sons Inc

Reutersward P, Bergström S, Orikiiriza J, Lindquist E, Svahn HA, Ayoglu B, Uhlen M, Wahlgren M, Normark J, Ribacke U, Nilsson P (2018) Levels of human proteins in plasma associated with acute paediatric malaria. Malar J 17: 19

Rodriguez A, Zhang HQ, Klaminder J, Brodin T, Andersson PL, Andersson M (2018) ToxTrac: A fast and robust software for tracking organisms. Methods in Ecology and Evolution 9: 460-464

Rogne P, Rosselin M, Grundstrom C, Hedberg C, Sauer UH, Wolf-Watz M (2018) Molecular mechanism of ATP versus GTP selectivity of adenylate kinase. Proceedings of the National Academy of Sciences of the United States of America 115: 3012-3017

Rusanganwa V, Gahutu JB, Nzabahimana I, Ngendakabaniga JMV, Hurtig AK, Evander M (2018) Clinical Referral Laboratories in Rwanda: The Status of Quality Improvement After 7 Years of the SLMTA Program. Am J Clin Pathol

Rzhepishevska O, Limanska N, Galkin M, Lacoma A, Lundquist M, Sokol D, Hakobyan S, Sjöstedt A, Prat C, Ramstedt M (2018) Characterization of clinically relevant model bacterial strains of Pseudomonas aeruginosa for anti-biofilm testing of materials. Acta Biomater 76: 99-107

Saleeb M, Mojica S, Eriksson AU, Andersson CD, Gylfe A, Elofsson M (2018) Natural product inspired library synthesis - Identification of 2,3-diarylbenzofuran and 2,3-dihydrobenzofuran based inhibitors of Chlamydia trachomatis. European Journal of Medicinal Chemistry 143: 1077-1089

Saleeb M, Sundin C, Aglar O, Pinto AF, Ebrahimi M, Forsberg Å, Schuler H, Elofsson M (2018) Structure-activity relationships for inhibitors of Pseudomonas aeruginosa exoenzyme S ADP-ribosyltransferase activity. European Journal of Medicinal Chemistry 143: 568-576

Sewe MO, Bunker A, Ingole V, Egondi T, Astrom DO, Hondula DM, Rocklov J, Schumann B (2018) Estimated Effect of Temperature on Years of Life Lost: A Retrospective Time-Series Study of Low-, Middle-, and High-Income Regions. Environ Health Perspect 126: 12

Sewe MO, Tozan Y, Ahlm C, Rocklöv J (2018) Author Correction: Using remote sensing environmental data to forecast malaria incidence at a rural district hospital in Western Kenya. Sci Rep 8: 5032

Shukla L, Moodie LWK, Kindahl T, Hedberg C (2018) Synthesis and Spectroscopic Properties of Fluorinated Coumarin Lysine Derivatives. J Org Chem 83: 4792-4799

Silander I, Hausmaninger T, Zelan M, Axner O (2018) Gas modulation refractometry for high-precision assessment of pressure under non-temperature-stabilized conditions. Journal of Vacuum Science & Technology A 36

Sjollema J, Zaat SAJ, Fontaine V, Ramstedt M, Luginbuehl R, Thevissen K, Li JY, van der Mei HC, Busscher HJ (2018) In vitro methods for the evaluation of antimicrobial surface designs. Acta Biomaterialia 70: 12-24

Skalman LN, Holst MR, Larsson E, Lundmark R (2018) Plasma membrane damage caused by listeriolysin O is not repaired through endocytosis of the membrane pore. Biol Open 7: 11

Soderholm N, Javadi A, Flores IS, Flardh K, Sandblad L (2018) Affinity to cellulose is a shared property among coiled-coil domains of intermediate filaments and prokaryotic intermediate filament-like proteins. Scientific Reports 8: 12

Spaulding C, Schreiber HL, Zheng WL, Dodson KW, Hazen JE, Conover M, Wang FB, Svenmarker P, Luna-Rico A, Francetic O, Andersson M, Hultgren S, Egelman EH (2018) Functional role of the type 1 pilus rod structure in mediating host-pathogen interactions. Elife 7

Stangner T, Dahlberg T, Svenmarker P, Zakrisson J, Wiklund K, Oddershede LB, Andersson M (2018) Cooke-Triplet tweezers: more compact, robust, and efficient optical tweezers. Optics Letters 43: 1990-1993

Surowiec I, Johansson E, Stenlund H, Rantapaa-Dahlqvist S, Bergström S, Normark J, Trygg J (2018) Quantification of run order effect on chromatography - mass spectrometry profiling data. J Chromatogr A 1568: 229-234

Taheri N, Mahmud A, Sandblad L, Fällman M, Wai SN, Fahlgren A (2018) Campylobacter jejuni bile exposure influences outer membrane vesicles protein content and bacterial interaction with epithelial cells. Scientific Reports 8: 14

Talagrand-Reboul E, Boyer PH, Bergström S, Vial L, Boulanger N (2018) Relapsing Fevers: Neglected Tick-Borne Diseases. Frontiers in Cellular and Infection Microbiology 8: 21

Thi Tuyet-Hanh T, Nhat Cam N, Thi Thanh Huong L, Khanh Long T, Mai Kien T, Thi Kim Hanh D, Huu Quyen N, Nu Quy Linh T, Rocklöv J, Quam M, Van Minh H (2018) Climate Variability and Dengue Hemorrhagic Fever in Hanoi, Viet Nam, During 2008 to 2015. Asia Pac J Public Health 30: 532-541

Thunström Salzer A, Niemiec MJ, Hosseinzadeh A, Stylianou M, Åström F, Röhm M, Ahlm C, Wahlin A, Ermert D, Urban CF (2018) Assessment of Neutrophil Chemotaxis Upon G-CSF Treatment of Healthy Stem Cell Donors and in Allogeneic Transplant Recipients. Front Immunol 9: 1968

Tsatsaronis JA, Franch-Arroyo S, Resch U, Charpentier E (2018) Extracellular Vesicle RNA: A Universal Mediator of Microbial Communication? Trends in Microbiology 26: 401-410

Urban CF, Nett JE (2018) Neutrophil extracellular traps in fungal infection. Semin Cell Dev Biol

van Mourik PM, de Jong J, Sharma S, Kavsek A, Chabes A, Chang M (2018) Upregulation of dNTP Levels After Telomerase Inactivation Influences Telomerase-Independent Telomere Maintenance Pathway Choice in Saccharomyces cerevisiae. G3-Genes Genomes Genet 8: 2551-2558

Vdovikova S, Gilfillan S, Wang SX, Dongre M, Wai SN, Hurtado A (2018) Modulation of gene transcription and epigenetics of colon carcinoma cells by bacterial membrane vesicles. Scientific Reports 8: 10

Veenaas C, Linusson A, Haglund P (2018) Retention-time prediction in comprehensive two-dimensional gas chromatography to aid identification of unknown contaminants. Anal Bioanal Chem 410: 7931-7941

Vonderstein K, Nilsson E, Hubel P, Skalman LN, Upadhyay A, Pasto J, Pichlmair A, Lundmark R, Överby AK (2018) Viperin Targets Flavivirus Virulence by Inducing Assembly of Noninfectious Capsid Particles. Journal of Virology 92: 15

Watts N, Amann M, Arnell N, Ayeb-Karlsson S, Belesova K, Berry H, Bouley T, Boykoff M, Byass P, Cai W, Campbell-Lendrum D, Chambers J, Daly M, Dasandi N, Davies M, Depoux A, Dominguez-Salas P, Drummond P, Ebi KL, Ekins P Montoya L F, Fischer H, Georgeson L, Grace D, Graham H, Hamilton I, Hartinger S, Hess J, Kelman I, Kiesewetter G, Kjellstrom T, Kniveton D, Lemke B, Liang L, Lott M, Lowe R, Sewe MO, Martinez-Urtaza J, Maslin M, McAllister L, Mikhaylov S, J, Milner J, Moradi-Lakeh M, Morrissey K, Murray K, Nilsson M, Neville T, Oreszczyn T, Owfi F, Pearman O, Pencheon D, Pye S, Robinson E, Rocklov J, Saxer O, Schutte S, Semenza J, C, Shumake-Guillemot J, Steinbach R, Tabatabaei M, Tomei J, Trinanes J, Wheeler N, Wilkinson P, Gong P, Montgomery H, Costello A (2018) The 2018 report of the Lancet Countdown on health and climate change: shaping the health of nations for centuries to come. Lancet 392: 2479-2514

Watts N, Amann M, Ayeb-Karlsson S, Belesova K, Bouley T, Boykoff M, Byass P, Cai W, Campbell-Lendrum D, Chambers J, Cox PM, Daly M, Dasandi N, Davies M, Depledge M, Depoux A, Dominguez-Salas P, Drummond P, Ekins P, Flahault A, Frumkin H, Georgeson L, Ghanei M, Grace D, Graham H, Grojsman R, Haines A, Hamilton I, Hartinger S, Johnson A, Kelman I, Kiesewetter G, Kniveton D, Liang L, Lott M, Lowe R, Mace G, Odhiambo Sewe M, Maslin M, Mikhaylov S, Milner J, Latifi A, M, Moradi-Lakeh M, Morrissey K, Murray K, Neville T, Nilsson M, Oreszczyn T,Owfi F, Pencheon D, Rabbaniha M, Robinson E, Rocklöv J, Schutte S, Shumake-Guillemot J, Steinbach R, Tabatabaei M, Wheeler N, Wilkinson P, Gong P, Montgomery H, Costello A. (2018) The Lancet Countdown on health and climate change: from 25 years of inaction to a global transformation for public health. Lancet 391: 581-630

Westerberg S, Hagbom M, Rajan A, Loitto V, Persson BD, Allard A, Nordgren J, Sharma S, Magnusson KE, Arnberg N, Svensson L (2018) Interaction of Human Enterochromaffin Cells with Human Enteric Adenovirus 41 Leads to Serotonin Release and Subsequent Activation of Enteric Glia Cells. Journal of Virology 92: 14

Wiklund K, Zhang HQ, Stangner T, Singh B, Bullitt E, Andersson M (2018) A drag force interpolation model for capsule-shaped cells in fluid flows near a surface. Microbiol-Sgm 164: 483-494

Wilder-Smith A, Tissera H, AbuBakar S, Kittayapong P, Logan J, Neumayr A, Rocklöv J, Byass P, Louis VR, Tozan Y, Massad E, Preet R (2018) Novel tools for the surveillance and control of dengue: findings by the dengueTools research consortium. Global Health Action 11: 11

Yadav AK, Espaillat A, Cava F (2018) Bacterial Strategies to Preserve Cell Wall Integrity Against Environmental Threats. Frontiers in Microbiology 9: 9

Yu CH, Gan HY, Serra-Cardona A, Zhang L, Gan SL, Sharma S, Johansson E, Chabes A, Xu RM, Zhang ZG (2018) A mechanism for preventing asymmetric histone segregation onto replicating DNA strands. Science 361: 1386-+

Zetterstrom CE, Uusitalo P, Qian WX, Hinch S, Caraballo R, Grundstrom C, Elofsson M (2018) Screening for Inhibitors of Acetaldehyde Dehydrogenase (AdhE) from Enterohemorrhagic Escherichia coli (EHEC). SLAS Discov 23: 815-822

Zhang J, Grundstrom C, Brännström K, Iakovleva I, Lindberg M, Olofsson A, Andersson PL, Sauer-Eriksson AE (2018) Interspecies Variation between Fish and Human Transthyretins in Their Binding of Thyroid-Disrupting Chemicals. Environmental Science & Technology 52: 11865-11874

Wiklund K, Zhang HQ, Stangner T, Singh B, Bullitt E, Andersson M (2018) A drag force interpolation model for capsule-shaped cells in fluid flows near a surface. Microbiol-Sgm 164: 483-494

Zhang Z, Aung KM, Uhlin BE, Wai SN (2018) Reversible senescence of human colon cancer cells after blockage of mitosis/cytokinesis caused by the CNF1 cyclomodulin from Escherichia coli. Scientific Reports 8: 11

Zhang HQ, Stangner T, Wiklund K, Andersson M (2018) Object plane detection and phase retrieval from single-shot holograms using multi-wavelength in-line holography. Applied Optics 57: 9855-9862

Zhao G, Hausmaninger T, Ma WG, Axner O (2018) Shot-noise-limited Doppler-broadened noise-immune cavity-enhanced optical heterodyne molecular spectrometry. Optics Letters 43: 715-718

Zheng WL, Spaulding CN, Schreiber HL, Dodson KW, Conover MS, Wang FB, Svenmarker P, Luna-Rico A, Francetic O, Andersson M, Hultgren SJ, Egelman EH (2018) Cryo-Em Structure of Type 1 Pilus. Biophysical Journal 114: 370A-370A

 

Publikationer 2017

Abraham NM, Liu L, Jutras BL, Yadav AK, Narasimhan S, Gopalakrishnan V, Ansari JM, Jefferson KK, Cava F, Jacobs-Wagner C, Fikrig E (2017) Pathogen-mediated manipulation of arthropod microbiota to promote infection. Proc Natl Acad Sci U S A 114: E781-E790

Affognon H, Mburu P, Hassan OA, Kingori S, Ahlm C, Sang R, Evander M (2017) Ethnic groups' knowledge, attitude and practices and Rift Valley fever exposure in Isiolo County of Kenya. PLoS Negl Trop Dis 11: e0005405

Andersson CD, Martinez N, Zeller D, Rondahl SH, Koza MM, Frick B, Ekstrom F, Peters J, Linusson A (2017) Changes in dynamics of alpha-chymotrypsin due to covalent inhibitors investigated by elastic incoherent neutron scattering. Phys Chem Chem Phys 19: 25369-25379

Avican U, Doruk T, Östberg Y, Fahlgren A, Forsberg Å (2017) The Tat Substrate SufI Is Critical for the Ability of Yersinia pseudotuberculosis To Cause Systemic Infection. Infect Immun 85

Bagnato P, Castagnino A, Cortese K, Bono M, Grasso S, Bellese G, Daniele T, Lundmark R, Defilippi P, Castagnola P, Tacchetti C (2017) Cooperative but distinct early co-signaling events originate from ERBB2 and ERBB1 receptors upon trastuzumab treatment in breast cancer cells. Oncotarget 8: 60109-60122

Basu B, Paul S, Kundu S, Byström E, Irgum K, Almqvist F (2017) Organic Polymeric Resins Embedded with Pd NPs: Newly Designed, Efficient and Chemoselective Catalyst for Reduction of Nitrobenzenes. Curr Organocatalysis 4: 48-61

Beljantseva J, Kudrin P, Andresen L, Shingler V, Atkinson GC, Tenson T, Hauryliuk V (2017) Negative allosteric regulation of Enterococcus faecalis small alarmone synthetase RelQ by single-stranded RNA. Proceedings of the National Academy of Sciences of the United States of America 114: 3726-3731

Beljantseva J, Kudrin P, Jimmy S, Ehn M, Pohl R, Varik V, Tozawa Y, Shingler V, Tenson T, Rejman D, Hauryliuk V (2017) Molecular mutagenesis of ppGpp: turning a RelA activator into an inhibitor. Scientific Reports 7: 10

Bitar A, De R, Melgar S, Aung KM, Rahman A, Qadri F, Wai SN, Shirin T, Hammarstrom ML (2017) Induction of immunomodulatory miR-146a and miR-155 in small intestinal epithelium of Vibrio cholerae infected patients at acute stage of cholera. PLoS One 12: e0173817

Bjornham O, Andersson M (2017) Theory for nonlinear dynamic force spectroscopy. European Biophysics Journal with Biophysics Letters 46: 225-233

Björnsdottir H, Dahlstrand Rudin A, Klose FP, Elmwall J, Welin A, Stylianou M, Christenson K, Urban CF, Forsman H, Dahlgren C, Karlsson A, Bylund J (2017) Phenol-Soluble Modulin alpha Peptide Toxins from Aggressive Staphylococcus aureus Induce Rapid Formation of Neutrophil Extracellular Traps through a Reactive Oxygen Species-Independent Pathway. Front Immunol 8: 257

Brännström K, Islam T, Sandblad L, Olofsson A (2017) The role of histidines in amyloid beta fibril assembly. Febs Letters 591: 1167-1175

Bröms JE, Meyer L, Sjöstedt A (2017) A mutagenesis-based approach identifies amino acids in the N-terminal part of Francisella tularensis IglE that critically control Type VI system-mediated secretion. Virulence 8: 821-847

Bugaytsova JA, Bjornham O, Chernov YA, Gideonsson P, Henriksson S, Mendez M, Sjostrom R, Mahdavi J, Shevtsova A, Ilver D, Moonens K, Quintana-Hayashi MP, Moskalenko R, Aisenbrey C, Bylund G, Schmidt A, Åberg A, Brannstrom K, Koniger V, Vikstrom S Rakhimova L, Hofer A, Ogren J, Liu H, Goldman MD, Whitmire JM, Aden J, Younson J, Kelly C. G, Gilman RH, Chowdhury A, Mukhopadhyay AK, Nair GB,Papadakos KS, Martinez-Gonzalez B, Sgouras DN, Engstrand L, Unemo M, Danielsson D, Suerbaum S, Oscarson S, Morozova-Roche LA, Olofsson A, Gröbner G, Holgersson J, Esberg A, Strömberg N, Landström M, Eldridge AM, Chromy BA, Hansen LM, Solnick JV, Linden SK, Haas R, Dubois A, Merrell DS, Schedin S, Remaut H, Arnqvist A, Berg DE, Borén T.(2017) Helicobacter pylori adapts to chronic infection and gastric disease via pH-responsive BabA-mediated adherence. Cell Host & Microbe 21: 376-389

Bunker A, Sewe MO, Sie A, Rocklöv J, Sauerborn R (2017) Excess burden of non-communicable disease years of life lost from heat in rural Burkina Faso: a time series analysis of the years 2000-2010. BMJ open 7: e018068

Castanheira S, Cestero JJ, Rico-Perez G, Garcia P, Cava F, Ayala JA, Pucciarelli MG, Garcia-del Portillo F (2017) A Specialized Peptidoglycan Synthase Promotes Salmonella Cell Division inside Host Cells. Mbio 8: 13

Cava F (2017) Divergent functional roles of D-amino acids secreted by Vibrio cholerae. Int Microbiol 20: 149-150

Cava F (2017) Biology of Vibrio cholerae Editorial overview. Int Microbiol 20: 1

Daste F, Walrant A, Holst MR, Gadsby JR, Mason J, Lee JE, Brook D, Mettlen M, Larsson E, Lee SF, Lundmark R, Gallop JL (2017) Control of actin polymerization via the coincidence of phosphoinositides and high membrane curvature. J Cell Biol 216: 3745-3765

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Ferreira M, Rzhepishevska O, Grenho L, Malheiros D, Gonccalves L, Almeida AJ, Jordao L, Ribeiro IA, Ramstedt M, Gomes P, Bettencourt A (2017) Levofloxacin-loaded bone cement delivery system: Highly effective against intracellular bacteria and Staphylococcus aureus biofilms. Int J Pharm 532: 241-248

Forsell J, Bengtsson-Palme J, Angelin M, Johansson A, Evengard B, Granlund M (2017) The relation between Blastocystis and the intestinal microbiota in Swedish travellers. BMC Microbiology 17:231

Francis MS, Amer AA, Milton DL, Costa TR (2017) Site-Directed Mutagenesis and Its Application in Studying the Interactions of T3S Components. Methods Mol Biol 1531: 11-31

Gan HY, Yu CH, Devbhandari S, Sharma S, Han JH, Chabes A, Remus D, Zhang ZG (2017) Checkpoint Kinase Rad53 Couples Leading- and Lagging-Strand DNA Synthesis under Replication Stress. Molecular Cell 68: 446-+

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Gekara NO (2017) DNA damage-induced immune response: Micronuclei provide key platform. Journal of Cell Biology 216: 2999-3001

Ginley BG, Emmons T, Lutnick B, Urban CF, Segal BH, Sarder P (2017) Computational detection and quantification of human and mouse neutrophil extracellular traps in flow cytometry and confocal microscopy. Sci Rep 7: 17755

Good JAD, Kulen M, Silver J, Krishnan KS, Bahnan W, Nunez-Otero C, Nilsson I, Wede E, de Groot E, Gylfe A, Bergström S, Almqvist F (2017) Thiazolino 2-Pyridone Amide Isosteres As Inhibitors of Chlamydia trachomatis Infectivity. J Med Chem 60: 9393-9399

Gupta A, Reinartz I, Spilotros A, Jonna VR, Hofer A, Svergun DI, Schug A, Wolf-Watz M (2017) Global Disordering in Stereo-Specific Protein Association. Biophysical Journal 112: 33A-33A

Gylfe Å, Cajander S, Wahab T, Angelin M (2017) Melioidos: en viktig diagnos vid svår sjukdom efter utlandsresa. Läkartidningen 114

Hall M, Wagner R, Lam XT, Funk C, Persson K (2017) The HhoA protease from Synechocystis sp PCC 6803-Novel insights into structure and activity regulation. J Struct Biol 198: 147-153

Hansen LM, Gideonsson P, Canfield DR, Borén T, Solnick JV (2017) Dynamic Expression of the BabA Adhesin and Its BabB Paralog during Helicobacter pylori Infection in Rhesus Macaques. Infection and Immunity 85: 14

Hassan OA, Affognon H, Rocklöv J, Mburu P, Sang R, Ahlm C, Evander M (2017) The One Health approach to identify knowledge, attitudes and practices that affect community involvement in the control of Rift Valley fever outbreaks. Plos Neglect Trop Dis 11: e0005383

Hauryliuk V, Atkinson GC (2017) Small Alarmone Synthetases as novel bacterial RNA-binding proteins. Rna Biology 14: 1695-1699

Ho O, Rogne P, Edgren T, Wolf-Watz H, Login FH, Wolf-Watz M (2017) Characterization of the Ruler Protein Interaction Interface on the Substrate Specificity Switch Protein in the Yersinia Type III Secretion System. J Biol Chem 292: 3299-3311

Hoernke M, Mohan J, Larsson E, Blomberg J, Kahra D, Westenhoff S, Schwieger C, Lundmark R (2017) EHD2 restrains dynamics of caveolae by an ATP-dependent, membrane-bound, open conformation. Proc Natl Acad Sci U S A 114: E4360-E4369

Holst MR, Vidal-Quadras M, Larsson E, Song J, Hubert M, Blomberg J, Lundborg M, Landstrom M, Lundmark R (2017) Clathrin-Independent Endocytosis Suppresses Cancer Cell Blebbing and Invasion. Cell Rep 20: 1893-1905

Honn M, Lindgren H, Bharath GK, Sjöstedt A (2017) Lack of OxyR and KatG Results in Extreme Susceptibility of Francisella tularensis LVS to Oxidative Stress and Marked Attenuation In vivo. Front Cell Infect Microbiol 7: 14

Howell M, Aliashkevich A, Salisbury AK, Cava F, Bowman GR, Brown PJB (2017) Absence of the Polar Organizing Protein PopZ Results in Reduced and Asymmetric Cell Division in Agrobacterium tumefaciens. J Bacteriol 199

Hubert M, Larsson E, Lundmark R (2017) Caveolae dynamics is strongly influenced by the lipid composition of the plasma membrane. European Biophysics Journal with Biophysics Letters 46: S121-S121

Hurwitz JL, Jones BG, Charpentier E, Woodland DL (2017) Hypothesis: RNA and DNA Viral Sequence Integration into the Mammalian Host Genome Supports Long-Term B Cell and T Cell Adaptive Immunity. Viral Immunol 30: 628-632

Ignatov D, Johansson J (2017) RNA-mediated signal perception in pathogenic bacteria. Wiley Interdiscip Rev RNA 8

Ingole V, Kovats S, Schumann B, Hajat S, Rocklov J, Juvekar S, Armstrong B (2017) Socioenvironmental factors associated with heat and cold-related mortality in Vadu HDSS, western India: a population-based case-crossover study. Int J Biometeorol 61: 1797-1804

Jacobsson S, Larsson P, Johansson G, Norberg M, Wadell G, Hallmans G, Winso O, Söderberg S (2017) Leptin independently predicts development of sepsis and its outcome. J Inflamm-Lond 14: 10

Jain N, Aden J, Nagamatsu K, Evans ML, Li XY, McMichael B, Ivanova MI, Almqvist F, Buxbaum JN, Chapman MR (2017) Inhibition of curli assembly and Escherichia coli biofilm formation by the human systemic amyloid precursor transthyretin. Proceedings of the National Academy of Sciences of the United States of America 114: 12184-12189

Jers C, Ravikumar V, Lezyk M, Sultan A, Sjoling A, Wai SN, Mijakovic I (2017) The Global Acetylome of the Human Pathogen Vibrio cholerae V52 Reveals Lysine Acetylation of Major Transcriptional Regulators. Front Cell Infect Microbiol 7: 537

Jonsson AK, Lovborg H, Lohr W, Ekman B, Rocklöv J (2017) Increased Risk of Drug-Induced Hyponatremia during High Temperatures. Int J Environ Res Public Health 14: 827

Kable ME, Hansen LM, Styer CM, Deck SL, Rakhimova O, Shevtsova A, Eaton KA, Martin ME, Gideonsson P, Borén T, Solnick JV (2017) Host Determinants of Expression of the Helicobacter pylori BabA Adhesin. Scientific Reports 7: 12

Kajan GL, Kajon AE, Pinto AC, Bartha D, Arnberg N (2017) The complete genome sequence of human adenovirus 84, a highly recombinant new Human mastadenovirus D type with a unique fiber gene. Virus Res 242: 79-84

Karah N, Jolley KA, Hall RM, Uhlin BE (2017) Database for the ampC alleles in Acinetobacter baumannii. PLoS One 12: e0176695

Khalil H, Olsson G, Magnusson M, Evander M, Hornfeldt B, Ecke F (2017) Spatial prediction and validation of zoonotic hazard through micro-habitat properties: where does Puumala hantavirus hole - up? BMC Infect Dis 17: 523

Kindstedt E, Holm CK, Sulniute R, Martinez-Carrasco I, Lundmark R, Lundberg P (2017) CCL11, a novel mediator of inflammatory bone resorption. Sci Rep 7: 5334

Knutsson S, Kindahl T, Engdahl C, Nikjoo D, Forsgren N, Kitur S, Ekstrom F, Kamau L, Linusson A (2017) N-Aryl-N'-ethyleneaminothioureas effectively inhibit acetylcholinesterase 1 from disease-transmitting mosquitoes. European Journal of Medicinal Chemistry 134: 415-427

Kochenova OV, Bezalel-Buch R, Tran P, Makarova AV, Chabes A, Burgers PMJ, Shcherbakova PV (2017) Yeast DNA polymerase zeta maintains consistent activity and mutagenicity across a wide range of physiological dNTP concentrations. Nucleic Acids Research 45: 1200-1218

Koukalova A, Amaro M, Aydogan G, Gröbner G, Williamson PTF, Mikhalyov I, Hof M, Sachl R (2017) Lipid Driven Nanodomains in Giant Lipid Vesicles are Fluid and Disordered. Scientific Reports 7: 5460

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Krajewski SS, Isoz I, Johansson J (2017) Antibacterial and antivirulence effect of 6-N-hydroxylaminopurine in Listeria monocytogenes. Nucleic Acids Res 45: 1914-1924

Kudrin P, Varik V, Oliveira SRA, Beljantseva J, Santos TDP, Dzhygyr I, Rejman D, Cava F, Tenson T, Hauryliuk V (2017) Subinhibitory Concentrations of Bacteriostatic Antibiotics Induce relA-Dependent and relA-Independent Tolerance to beta-Lactams. Antimicrobial Agents and Chemotherapy 61: 17

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Kumar K, Espaillat A, Cava F (2017) PG-Metrics: A chemometric-based approach for classifying bacterial peptidoglycan data sets and uncovering their subjacent chemical variability. Plos One 12: 25

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Le Rhun A, Lecrivain AL, Reimegard J, Proux-Wera E, Broglia L, Della Beffa C, Charpentier E (2017) Identification of endoribonuclease specific cleavage positions reveals novel targets of RNase III in Streptococcus pyogenes. Nucleic Acids Res 45: 2329-2340

Lindgren C, Forsgren N, Akfur C, Berg L, Andersson D, Hillgren M, Qian WX, Worek F, Ekstrom F, Linusson A (2017) Development of antidotes against nerve agent inhibited acetylcholinesterase - the transformation of an inhibitor into a reactivator. Abstracts of Papers of the American Chemical Society 253

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Maciejewska B, Roszniowski B, Espaillat A, Kesik-Szeloch A, Majkowska-Skrobek G, Kropinski AM, Briers Y, Cava F, Lavigne R, Drulis-Kawa Z (2017) Klebsiella phages representing a novel clade of viruses with an unknown DNA modification and biotechnologically interesting enzymes. Applied Microbiology and Biotechnology 101: 673-684

Maciejewska B, Zrubek K, Espaillat A, Wisniewska M, Rembacz KP, Cava F, Dubin G, Drulis-Kawa Z (2017) Modular endolysin of Burkholderia AP3 phage has the largest lysozyme-like catalytic subunit discovered to date and no catalytic aspartate residue. Scientific Reports 7: 12

Maicher A, Gazy I, Sharma S, Marjavaara L, Grinberg G, Shemesh K, Chabes A, Kupiec M (2017) Rnr1, but not Rnr3, facilitates the sustained telomerase-dependent elongation of telomeres. PLoS genetics 13: 22

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Melo AA, Hegde BG, Shah C, Larsson E, Isas JM, Kunz S, Lundmark R, Langen R, Daumke O (2017) Structural insights into the activation mechanism of dynamin-like EHD ATPases. Proc Natl Acad Sci U S A 114: 5629-5634

Milhano N, Korslund L, Evander M, Ahlm C, Vainio K, Dudman SG, Andreassen A (2017) Circulation and diagnostics of Puumala virus in Norway: nephropatia epidemica incidence and rodent population dynamics. Apmis 125: 732-742

Mojica SA, Salin O, Bastidas RJ, Sunduru N, Hedenstrom M, Andersson CD, Nunez-Otero C, Engstrom P, Valdivia RH, Elofsson M, Gylfe A (2017) N-Acylated Derivatives of Sulfamethoxazole Block Chlamydia Fatty Acid Synthesis and Interact with FabF. Antimicrobial Agents and Chemotherapy 61: 14

Moodie LWK, Chammaa S, Kindahl T, Hedberg C (2017) Palladium-Mediated Approach to Coumarin-Functionalized Amino Acids. Organic Letters 19: 2797-2800

Morell ML, Carcamo JRP, Vazquez CA, Vatansever S, Upadhyay AS, Överby AK, Cordo SM, Garcia CC (2017) Viperin exerts antiviral function against Junin mammarenavirus at different subcellular localizations. Molecular Biology of the Cell 28: 2

Moreno-Guzman M, Garcia-Carmona L, Molinero-Fernandez A, Cava F, Lopez Gil MA, Escarpa A (2017) Bi-enzymatic biosensor for on-site, fast and reliable electrochemical detection of relevant D-amino acids in bacterial samples. Sensors and actuators B, Chemical 242: 95-101

Nakamura M, Överby AK, Tomohiro A, Flahou B, Haesebrouck F, Matsui H (2017) Characteristics of cultured non-Helicobacter pylori Helicobacter and its relation to human gastric diseases. Helicobacter 22: 1

Nasstrom E, Parry CM, Thieu NTV, Maude RR, de Jong HK, Fukushima M, Rzhepishevska O, Marks F, Panzner U, Im J, Jeon H, Park S, Chaudhury Z, Ghose A, Samad R, Van TT, Johansson A, Dondorp AM, Thwaites GE, Faiz A et al. (2017) Reproducible diagnostic metabolites in plasma from typhoid fever patients in Asia and Africa. Elife 6: e15651

Niemiec MJ, Grumaz C, Ermert D, Desel C, Shankar M, Lopes JP, Mills IG, Stevens P, Sohn K, Urban CF (2017) Dual transcriptome of the immediate neutrophil and Candida albicans interplay. BMC Genomics 18: 696

Nystrom K, Pettersson G, Wanrooij PH, Brunet S, Said J, Ortolani G, Waldenstrom J, Adamek L, Tang KW, Norberg P, Chabes A, Hellstrand K, Norder H, Lagging M (2017) Inosine triphosphate pyrophosphatase enhances the effect of ribavirin on hepatitis C virus cell culture infection. Journal of Hepatology 66: S321-S321

Orikiiriza J, Surowiec I, Lindquist E, Bonde M, Magambo J, Muhinda C, Bergström S, Trygg J, Normark J (2017) Lipid response patterns in acute phase paediatric Plasmodium falciparum malaria. Metabolomics 13: 41

Orikiiriza J, Nakawesi J, Kikaire B, Turitwenka D, Schlech W, Kambugu A, Lamorde M, Normark J, Hennessy M, Musiime V, Rujumba J, Ndeezi G, Tumwesigye NM, Doherty DG, Achan J (2017) Unmet needs persist in pediatric HIV programs: lessons from selected case studies in Uganda. Aids 31: 1196-1199

Pokrzywa M, Pawelek K, Kucia WE, Sarbak S, Chorell E, Almqvist F, Wittung-Stafshede P (2017) Effects of small-molecule amyloid modulators on a Drosophila model of Parkinson's disease. Plos One 12: 21

Putzova D, Panda S, Härtlova A, Stulik J, Gekara NO (2017) Subversion of innate immune responses by Francisella involves the disruption of TRAF3 and TRAF6 signalling complexes. Cellular Microbiology 19: 11

Qin LN, Vo DD, Nakhai A, Andersson CD, Elofsson M (2017) Diversity-Oriented Synthesis of Libraries Based on Benzofuran and 2,3-Dihydrobenzofuran Scaffolds. ACS Comb Sci 19: 370-376

Quam VGM, Rocklöv J, Quam MBM, Lucas RAI (2017) Assessing Greenhouse Gas Emissions and Health Co-Benefits: A Structured Review of Lifestyle-Related Climate Change Mitigation Strategies. Int J Environ Res Public Health 14

Reimer J, Knoss S, Labuhn M, Charpentier EM, Gohring G, Schlegelberger B, Klusmann JH, Heckl D (2017) CRISPR-Cas9-induced t(11;19)/MLL-ENL translocations initiate leukemia in human hematopoietic progenitor cells in vivo. Haematologica 102: 1558-1566

Renault TT, Abraham AO, Bergmiller T, Paradis G, Rainville S, Charpentier E, Guet CC, Tu Y, Namba K, Keener JP, Minamino T, Erhardt M (2017) Bacterial flagella grow through an injection-diffusion mechanism. eLife 6

Richter F, Fonfara I, Gelfert R, Nack J, Charpentier E, Moglich A (2017) Switchable Cas9. Current Opinion in Biotechnology 48: 119-126

Rodriguez A, Zhang HH, Wiklund K, Brodin T, Klaminder J, Andersson P, Andersson M (2017) Refining particle positions using circular symmetry. Plos One 12

Rodriguez A, Zhang HQ, Klaminder J, Brodin T, Andersson M (2017) ToxId: an efficient algorithm to solve occlusions when tracking multiple animals. Scientific Reports 7

Rutkowski L, Johansson AC, Zhao G, Hausmaninger T, Khodabakhsh A, Axner O, Foltynowicz A (2017) Sensitive and broadband measurement of dispersion in a cavity using a Fourier transform spectrometer with kHz resolution. Optics Express 25: 21711-21718

Sang R, Arum S, Chepkorir E, Mosomtai G, Tigoi C, Sigei F, Lwande OW, Landmann T, Affognon H, Ahlm C, Evander M (2017) Distribution and abundance of key vectors of Rift Valley fever and other arboviruses in two ecologically distinct counties in Kenya. Plos Neglect Trop Dis 11: e0005341.

Schmidt TT, Reyes G, Gries K, Ceylan CU, Sharma S, Meurer M, Knop M, Chabes A, Hombauer H (2017) Alterations in cellular metabolism triggered by URA7 or GLN3 inactivation cause imbalanced dNTP pools and increased mutagenesis. Proceedings of the National Academy of Sciences of the United States of America 114: E4442-E4451

Schmitt DM, Barnes R, Rogerson T, Haught A, Mazzella LK, Ford M, Gilson T, Birch JW, Sjöstedt A, Reed DS, Franks JM, Stolz DB, Denvir J, Fan J, Rekulapally S, Primerano DA, Horzempa J (2017) The Role and Mechanism of Erythrocyte Invasion by Francisella tularensis. Front Cell Infect Microbiol 7: 173

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Semenza JC, Trinanes J, Lohr W, Sudre B, Lofdahl M, Martinez-Urtaza J, Nichols GL, Rocklöv J (2017) Environmental Suitability of Vibrio Infections in a Warming Climate: An Early Warning System. Environ Health Perspect 125: 107004

Sewe MO, Tozan Y, Ahlm C, Rocklöv J (2017) Using remote sensing environmental data to forecast malaria incidence at a rural district hospital in Western Kenya. Sci Rep 7: 2589

Shchukarev A, Ramstedt M (2017) Cryo-XPS: probing intact interfaces in nature and life. Surf Interface Anal 49: 349-356

Singh B, Mortezaei N, Savarino SJ, Uhlin BE, Bullitt E, Andersson M (2017) Antibodies Damage the Resilience of Fimbriae, Causing Them To Be Stiff and Tangled. J Bacteriol 199: e00665-16

Sironen T, Sane J, Lokki ML, Meri S, Andersson LC, Hautala T, Kauma H, Vuorinen S, Rasmuson J, Evander M, Ahlm C, Vaheri A (2017) Fatal Puumala Hantavirus Disease: Involvement of Complement Activation and Vascular Leakage in the Pathobiology. Open Forum Infect Dis 4: ofx229

Skoog EC, Padra M, Åberg A, Gideonsson P, Obi I, Quintana-Hayashi MP, Arnqvist A, Linden SK (2017) BabA dependent binding of Helicobacter pylori to human gastric mucins cause aggregation that inhibits proliferation and is regulated via ArsS. Scientific Reports 7: 14

Stangner T, Zhang HQ, Dahlberg T, Wiklund K, Andersson M (2017) Step-by-step guide to reduce spatial coherence of laser light using a rotating ground glass diffuser. Applied Optics 56: 5427-5435

Storm RJ, Persson BD, Skalman LN, Frangsmyr L, Lindstrom M, Rankin G, Lundmark R, Domellof FP, Arnberg N (2017) Human Adenovirus Type 37 Uses alpha(V)beta(1) and alpha(3)beta(1) Integrins for Infection of Human Corneal Cells. Journal of Virology 91: 14

Sunduru N, Svensson M, Cipriano M, Marwaha S, Andersson CD, Svensson R, Fowler CJ, Elofsson M (2017) N-aryl 2-aryloxyacetamides as a new class of fatty acid amide hydrolase (FAAH) inhibitors. J Enzym Inhib Med Chem 32: 513-521

Surowiec I, Gouveia-Figueira S, Orikiiriza J, Lindquist E, Bonde M, Magambo J, Muhinda C, Bergström S, Normark J, Trygg J (2017) The oxylipin and endocannabidome responses in acute phase Plasmodium falciparum malaria in children. Malar J 16: 16

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Terceti MS, Rivas AJ, Alvarez L, Noia M, Cava F, Osorio CR (2017) rstB Regulates Expression of the Photobacterium damselae subsp damselae Major Virulence Factors Damselysin, Phobalysin P and Phobalysin C. Frontiers in Microbiology 8: 11

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Vidal-Quadras M, Holst MR, Francis MK, Larsson E, Hachimi M, Yau WL, Peranen J, Martin-Belmonte F, Lundmark R (2017) Endocytic turnover of Rab8 controls cell polarization. J Cell Sci 130: 1147-1157

Vo DD, Elofsson M (2017) Synthesis of 4-Formyl-2-arylbenzofuran Derivatives by PdCl(C3H5)dppb-Catalyzed Tandem Sonogashira Coupling-Cyclization under Microwave Irradiation - Application to the Synthesis of Viniferifuran Analogues. ChemistrySelect 2: 6245-6248

Wallet P, Benaoudia S, Mosnier A, Lagrange B, Martin A, Lindgren H, Golovliov I, Michal F, Basso P, Djebali S, Provost A, Allatif O, Meunier E, Broz P, Yamamoto M, Py BF, Faudry E, Sjöstedt A, Henry T (2017) IFN-gamma extends the immune functions of Guanylate Binding Proteins to inflammasome-independent antibacterial activities during Francisella novicida infection. PLoS Pathog 13: e1006630

Wanrooij PH, Engqvist MKM, Forslund JME, Navarrete C, Nilsson AK, Sedman J, Wanrooij S, Clausen AR, Chabes A (2017) Ribonucleotides incorporated by the yeast mitochondrial DNA polymerase are not repaired. Proceedings of the National Academy of Sciences of the United States of America 114: 12466-12471

Webster SJ, Brode S, Ellis L, Fitzmaurice TJ, Elder MJ, Gekara NO, Tourlomousis P, Bryant C, Clare S, Chee R, Gaston HJS, Goodall JC (2017) Detection of a microbial metabolite by STING regulates inflammasome activation in response to Chlamydia trachomatis infection. Plos Pathogens 13: 23

Wixe T, Almqvist F (2017) An improved synthesis of 3- 1-(trifluoromethy1)-3H-1,2-diazirin-3-yl aniline: A key intermediate in the synthesis of photoaffinity probes. Tetrahedron Letters 58: 3350-3352

Zhang HI, Stangner T, Wiklund K, Rodriguez A, Andersson M (2017) UmUTracker: A versatile MATLAB program for automated particle tracking of 2D light microscopy or 3D digital holography data. Computer Physics Communications 219: 390-399

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Publikationer 2016

saknas

 

Pubikationer 2015

Afset JE, Larssen KW, Bergh K, Larkeryd A, Sjodin A, Johansson A, Forsman M (2015) Phylogeographical pattern of Francisella tularensis in a nationwide outbreak of tularaemia in Norway, 2011. Eurosurveillance 20: 9-14

Andersson C, Gripenland J, Johansson J (2015) Using the chicken embryo to assess virulence of Listeria monocytogenes and to model other microbial infections. Nat Protoc 10: 1155-64

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Silander I, Hausmaninger T, Ma WG, Ehlers P, Axner O (2015) Doppler-broadened noise-immune cavity-enhanced optical heterodyne molecular spectrometry down to 4 x 10(-13) cm(-1) Hz(-1/2): implementation of a 50,000 finesse cavity. Optics Letters 40: 2004-2007

Simon S, Schell U, Heuer N, Hager D, Albers MF, Matthias J, Fahrnbauer F, Trauner D, Eichinger L, Hedberg C, Hilbi H (2015) Inter-kingdom Signaling by the Legionella Quorum Sensing Molecule LAI-1 Modulates Cell Migration through an IQGAP1-Cdc42-ARHGEF9-Dependent Pathway. Plos Pathogens 11: 30

Singh B, Mortezaei N, Uhlin BE, Savarino SJ, Bullitt E, Andersson M (2015) Antibody-mediated disruption of the mechanics of CS20 fimbriae of enterotoxigenic Escherichia coli. Scientific Reports 5: 13678

Singh P, Chorell E, Krishnan KS, Kindahl T, Aden J, Wittung-Stafshede P, Almqvist F (2015) Synthesis of Multiring Fused 2-Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of alpha-Synuclein Amyloid Formation. Organic Letters 17: 6194-6197

Sjöström AE, Sandblad L, Uhlin BE, Wai SN (2015) Membrane vesicle-mediated release of bacterial RNA. Scientific Reports 5: 10

Struchiner CJ, Rocklöv J, Wilder-Smith A, Massad E (2015) Increasing Dengue Incidence in Singapore over the Past 40 Years: Population Growth, Climate and Mobility. PLoS One 10: e0136286

Stylianou M, Uvell H, Lopes JP, Enquist P-A, Elofsson M, Urban CF (2015) Novel High-Throughput Screening Method for Identification of Fungal Dimorphism Blockers. Journal of Biomolecular Screening 20: 285-291

Sunduru N, Salin O, Gylfe A, Elofsson M (2015) Design, synthesis and evaluation of novel polypharmacological antichlamydial agents. European Journal of Medicinal Chemistry 101: 595-603

Surowiec I, Orikiiriza J, Karlsson E, Nelson M, Bonde M, Kyamanwa P, Karenzi B, Bergström S, Trygg J, Normark J (2015) Metabolic Signature Profiling as a Diagnostic and Prognostic Tool in Pediatric Plasmodium falciparum Malaria. Open Forum Infect Dis 2: 10

Trentin DS, Silva DB, Frasson AP, Rzhepishevska O, da Silva MV, Pulcini ED, James G, Soares GV, Tasca T, Ramstedt M, Giordani RB, Lopes NP, Macedo AJ (2015) Natural Green Coating Inhibits Adhesion of Clinically Important Bacteria. Scientific Reports 5: 10

Turkina MV, Olofsson A, Magnusson K-E, Arnqvist A, Vikström E (2015) Helicobacter pylori vesicles carrying CagA localize in the vicinity of cell-cell contacts and induce histone H1 binding to ATP in epithelial cells. Fems Microbiology Letters 362

van Teeseling MCF, Mesman RJ, Kuru E, Espaillat A, Cava F, Brun YV, VanNieuwenhze MS, Kartal B, van Niftrik L (2015) Anammox Planctomycetes have a peptidoglycan cell wall. Nature Communications 6: 6

Vanhove AS, Duperthuy M, Charriere GM, Le Roux F, Goudenege D, Gourbal B, Kieffer-Jaquinod S, Coute Y, Wai SN, Destoumieux-Garzon D (2015) Outer membrane vesicles are vehicles for the delivery of Vibrio tasmaniensis virulence factors to oyster immune cells. Environmental Microbiology 17: 1152-1165

Williams JS, Clausen AR, Lujan SA, Marjavaara L, Clark AB, Burgers PM, Chabes A, Kunkel TA (2015) Evidence that processing of ribonucleotides in DNA by topoisomerase 1 is leading-strand specific. Nature Structural & Molecular Biology 22: 291-U35

Williams LN, Marjavaara L, Knowels GM, Schultz EM, Fox EJ, Chabes A, Herr AJ (2015) dNTP pool levels modulate mutator phenotypes of error-prone DNA polymerase epsilon variants. Proceedings of the National Academy of Sciences of the United States of America 112: E2457-E2466

Wolf-Watz M, Kovermann M (2015) Dynamics of a Naturally Hidden State Restricts Adenylate Kinase Activity. Biophysical Journal 108: 30A-30A

Zakrisson J, Wiklund K, Axner O, Andersson M (2015) Tethered cells in fluid flows-beyond the Stokes' drag force approach. Physical Biology 12: 056006

Zakrisson J, Wiklund K, Servin M, Axner O, laCoursiere C, Andersson M (2015) Rigid multibody simulation of a helix-like structure: the dynamics of bacterial adhesion pili. European Biophysics Journal with Biophysics Letters 44: 291-300

Zakrisson J, Schedin S, Andersson M (2015) Cell shape identification using digital holographic microscopy. Applied Optics 54: 7442-7448

Zegenhagen L, Weber E, Kurade C, Nair S, Överby AK, Kroeger A (2015) Differential innate immune responses in various brain regions regulate antiviral response in the CNS during Tick-borne encephalitis virus infection. Cytokine 76: 91-91

Zwack EE, Snyder AG, Wynosky-Dolfi MA, Ruthel G, Philip NH, Marketon MM, Francis MS, Bliska JB, Brodsky IE (2015) Inflammasome Activation in Response to the Yersinia Type III Secretion System Requires Hyperinjection of Translocon Proteins YopB and YopD. Mbio 6: e02095-14

 

Publikationer 2014

Åberg A, Gideonsson P, Vallstrom A, Olofsson A, Ohman C, Rakhimova L, Borén T, Engstrand L, Brannstrom K, Arnqvist A (2014) A repetitive DNA element regulates expression of the Helicobacter pylori sialic acid binding adhesin by a rheostat-like mechanism. PLoS Pathog 10: e1004234

Ahlm C, Eliasson M, Vapalahti O, Evander M (2014) Seroprevalence of Sindbis virus and associated risk factors in northern Sweden. Epidemiol Infect 142: 1559-65

Alvarez L, Espaillat A, Hermoso JA, de Pedro MA, Cava F (2014) Peptidoglycan Remodeling by the Coordinated Action of Multispecific Enzymes. Microbial Drug Resistance 20: 190-198

Ariza-Miguel J, Johansson A, Fernandez-Natal MI, Martinez-Nistal C, Orduna A, Rodriguez-Ferri EF, Hernandez M, Rodriguez-Lazaro D (2014) Molecular Investigation of Tularemia Outbreaks, Spain, 1997-2008. Emerging Infectious Diseases 20: 754-761

Asghar N, Lindblom P, Melik W, Lindqvist R, Haglund M, Forsberg P, Överby AK, Andreassen A, Lindgren PE, Johansson M (2014) Tick-Borne Encephalitis Virus Sequenced Directly from Questing and Blood-Feeding Ticks Reveals Quasispecies Variance. Plos One 9: 8

Atkinson GC, Kuzmenko A, Chicherin I, Soosaar A, Tenson T, Carr M, Kamenski P, Hauryliuk V (2014) An evolutionary ratchet leading to loss of elongation factors in eukaryotes. BMC Evolutionary Biology 14: 9

Axner O, Ehlers P, Hausmaninger T, Silander I, Ma W (2014) Noise-immune cavity-enhanced analytical atomic spectrometry - NICE-AAS - A technique for detection of elements down to zeptogram amounts. Spectrochimica Acta Part B-Atomic Spectroscopy 100: 211-235

Bao XF, Gylfe A, Sturdevant GL, Gong Z, Xu S, Caldwell HD, Elofsson M, Fan HZ (2014) Benzylidene Acylhydrazides Inhibit Chlamydial Growth in a Type III Secretion- and Iron Chelation-Independent Manner. Journal of Bacteriology 196: 2989-3001

Barbero DR, Boulanger N, Ramstedt M, Yu JC (2014) Nano-Engineering of SWNT Networks for Enhanced Charge Transport at Ultralow Nanotube Loading. Adv Mater 26: 3111-3117

Barcena-Uribarri I, Thein M, Barbot M, Sans-Serramitjana E, Bonde M, Mentele R, Lottspeich F, Bergström S, Benz R (2014) Study of the Protein Complex, Pore Diameter, and Pore-forming Activity of the Borrelia burgdorferi P13 Porin. Journal of Biological Chemistry 289: 18614-18624

Bareclev C, Vaitkevicius K, Netterling S, Johansson J (2014) DExD-box RNA-helicases in Listeria monocytogenes are important for growth, ribosomal maturation, rRNA processing and virulence factor expression. RNA Biol 11: 1457-1466

Birdsell DN, Johansson A, Ohrman C, Kaufman E, Molins C, Pearson T, Gyuranecz M, Naumann A, Vogler AJ, Myrtennas K, Larsson P, Forsman M, Sjodin A, Gillece JD, Schupp J, Petersen JM, Keim P, Wagner DM (2014) Francisella tularensis subsp tularensis Group A.I, United States. Emerging Infectious Diseases 20: 861-865

Bobay BG, Thompson RJ, Milton DL, Cavanagh J (2014) Chemical shift assignments and secondary structure prediction of the phosphorelay protein VanU from Vibrio anguillarum. Biomolecular Nmr Assignments 8: 177-179

Borén T (2014) Helicobacter pylori; multitalented adaptation of binding properties. Anticancer Research 34: 5840-5841

Brännström K, Ohman A, Nilsson L, Pihl M, Sandblad L, Oloisson A (2014) The N-terminal Region of Amyloid beta Controls the Aggregation Rate and Fibril Stability at Low pH Through a Gain of Function Mechanism. Journal of the American Chemical Society 136: 10956-10964

Buckland RJ, Watt DL, Chittoor B, Nilsson AK, Kunkel TA, Chabes A (2014) Increased and Imbalanced dNTP Pools Symmetrically Promote Both Leading and Lagging Strand Replication Infidelity. PLoS genetics 10: 8

Cava F, de Pedro MA (2014) Peptidoglycan plasticity in bacteria: emerging variability of the murein sacculus and their associated biological functions. Current Opinion in Microbiology 18: 46-53

Charpentier E (2014) Programmable RNA-guided Cas9 endonuclease: a novel tool for genome engineering. Transgenic Research 23: 188-189

Charpentier E, Marraffini LA (2014) Harnessing CRISPR-Cas9 immunity for genetic engineering. Curr Opin Microbiol 19: 114-119

Charpentier E, Marraffini LA (2014) Editorial overview: Novel technologies in microbiology: Recent advances in techniques in microbiology. Curr Opin Microbiol 19: viii-x

Chylinski K, Makarova KS, Charpentier E, Koonin EV (2014) Classification and evolution of type II CRISPR-Cas systems. Nucleic Acids Research 42: 6091-6105

Coenye T, Van Dijck P, Bjarnsholt T, Forsberg Å (2014) Microbial biofilms - the coming of age of a research field. Pathogens and Disease 70: 203-204

Dang HT, Chorell E, Uvell H, Pinkner JS, Hultgren SJ, Almqvist F (2014) Syntheses and biological evaluation of 2-amino-3-acyl-tetrahydrobenzothiophene derivatives; antibacterial agents with antivirulence activity. Organic & Biomolecular Chemistry 12: 1942-1956

Davis RA, Beattie KD, Xu M, Yang X, Yin S, Holla H, Healy PC, Sykes M, Shelper T, Avery VM, Elofsson M, Sundin C, Quinn RJ (2014) Solving the Supply of Resveratrol Tetramers from Papua New Guinean Rainforest Anisoptera Species That Inhibit Bacterial Type Ill Secretion Systems. Journal of Natural Products 77: 2633-2640

De Pascalis R, Chou AY, Ryden P, Kennett NJ, Sjöstedt A, Elkins KL (2014) Models Derived from In Vitro Analyses of Spleen, Liver, and Lung Leukocyte Functions Predict Vaccine Efficacy against the Francisella tularensis Live Vaccine Strain (LVS). Mbio 5 (2): e00936-13

Desmarais SM, Cava F, de Pedro MA, Huang KC (2014) Isolation and Preparation of Bacterial Cell Walls for Compositional Analysis by Ultra Performance Liquid Chromatography. J Vis Exp: 7

Dias RP, da Hora GCA, Ramstedt M, Soares TA (2014) Outer Membrane Remodeling: The Structural Dynamics and Electrostatics of Rough Lipopolysaccharide Chemotypes. J Chem Theory Comput 10: 2488-2497

Domkin V, Chabes A (2014) Phosphines are ribonucleotide reductase reductants that act via C-terminal cysteines similar to thioredoxins and glutaredoxins. Scientific Reports 4: 7

Dörr T, Lam H, Alvarez L, Cava F, Davis BM, Waldor MK (2014) A Novel Peptidoglycan Binding Protein Crucial for PBP1A-Mediated Cell Wall Biogenesis in Vibrio cholerae. PLoS genetics 10: 14

Dörr T, Moll A, Chao MC, Cava F, Lam H, Davis BM, Waldor MK (2014) Differential Requirement for PBP1a and PBP1b in In Vivo and In Vitro Fitness of Vibrio cholerae. Infection and Immunity 82: 2115-2124

Doudna JA, Charpentier E (2014) The new frontier of genome engineering with CRISPR-Cas9. Science 346: 1077-+

Doudna JA, Charpentier E (2014) Genome editing. The new frontier of genome engineering with CRISPR-Cas9. Science 346: 1258096

Edwin A, Grundström C, Wai SN, Öhman A, Stier G, Sauer-Eriksson AE (2014) Domain isolation, expression, purification and proteolytic activity of the metalloprotease PrtV from Vibrio cholerae. Protein Expression and Purification 96: 39-47

Ehlers P, Johansson AC, Silander I, Foltynowicz A, Axner O (2014) Use of etalon-immune distances to reduce the influence of background signals in frequency-modulation spectroscopy and noise-immune cavity-enhanced optical heterodyne molecular spectroscopy. Journal of the Optical Society of America B-Optical Physics 31: 2938-2945

Ehlers P, Silander I, Wang J, Foltynowicz A, Axner O (2014) Fiber-laser-based noise-immune cavity-enhanced optical heterodyne molecular spectrometry incorporating an optical circulator. Optics Letters 39: 279-282

Ehlers P, Wang J, Silander I, Axner O (2014) Doppler broadened NICE-OHMS beyond the triplet formalism: assessment of optimum modulation index. Journal of the Optical Society of America B-Optical Physics 31: 1499-1507

Elbir H, Larsson P, Normark J, Upreti M, Korenberg E, Larsson C, Bergström S (2014) Genome Sequence of the Asiatic Species Borrelia persica. Genome announcements 2

Elbir H, Larsson P, Upreti M, Normark J, Bergström S (2014) Genome Sequence of the Relapsing Fever Borreliosis Species Borrelia hispanica. Genome Announc 2

Elluri S, Enow C, Vdovikova S, Rompikuntal PK, Dongre M, Carlsson S, Pal A, Uhlin BE, Wai SN (2014) Outer membrane vesicles mediate transport of biologically active Vibrio cholerae cytolysin (VCC) from V. cholerae strains. PLoS One 9: e106731

Engdahl C, Larsson P, Naslund J, Bravo M, Evander M, Lundström JO, Ahlm C, Bucht G (2014) Identification of Swedish mosquitoes based on molecular barcoding of the COI gene and SNP analysis. Mol Ecol Resour 14: 478-488

Enow COA, Oscarsson J, Zlatkov N, Westermark M, Duperthuy M, Wai SN, Uhlin BE (2014) Elevated recombinant clyA gene expression in the uropathogenic Escherichia coli strain 536, a clue to explain pathoadaptive mutations in a subset of extraintestinal E. coli strains. Bmc Microbiology 14: 216

Erttmann SF, Gekara NO, Fällman M (2014) Bacteria Induce Prolonged PMN Survival via a Phosphatidylcholine-Specific Phospholipase C- and Protein Kinase C-Dependent Mechanism. Plos One 9: 14

Espaillat A, Carrasco-Lopez C, Bernardo-Garcia N, Pietrosemoli N, Otero LH, Alvarez L, de Pedro MA, Pazos F, Davis BM, Waldor MK, Hermoso JA, Cava F (2014) Structural basis for the broad specificity of a new family of amino-acid racemases. Acta Crystallographica Section D-Biological Crystallography 70: 79-90

Fahlgren A, Avican K, Westermark L, Nordfelth R, Fällman M (2014) Colonization of cecum is important for development of persistent infection by Yersinia pseudotuberculosis. Infect Immun 82: 3471-3482

Fleury C, Su YC, Hallstrom T, Sandblad L, Zipfel PF, Riesbeck K (2014) Identification of a Haemophilus influenzae Factor H-Binding Lipoprotein Involved in Serum Resistance. Journal of Immunology 192: 5913-5923

Fonfara I, Le Rhun A, Chylinski K, Makarova KS, Lecrivain A-L, Bzdrenga J, Koonin EV, Charpentier E (2014) Phylogeny of Cas9 determines functional exchangeability of dual-RNA and Cas9 among orthologous type II CRISPR-Cas systems. Nucleic Acids Research 42: 2577-2590

Greene SE, Pinkner JS, Chorell E, Dodson KW, Shaffer CL, Conover MS, Livny J, Hadjifrangiskou M, Almqvist F, Hultgren SJ (2014) Pilicide ec240 Disrupts Virulence Circuits in Uropathogenic Escherichia coli. Mbio 5: 14

Gripenland J, Andersson C, Johansson J (2014) Exploring the chicken embryo as a possible model for studying Listeria monocytogenes pathogenicity. Front Cell Infect Microbiol 4: 170

Hakobyan S, Boily JF, Ramstedt M (2014) Proton and gallium(III) binding properties of a biologically active salicylidene acylhydrazide. Journal of Inorganic Biochemistry 138: 9-15

Hall M, Nylander A, Jenkinson HF, Persson K (2014) Structure of the C-terminal domain of AspA (antigen I/II-family) protein from Streptococcus pyogenes. Febs Open Bio 4: 283-289

Hanski L, Genina N, Uvell H, Malinovskaja K, Gylfe Å, Laaksonen T, Kolakovic R, Mäkilä E, Salonen J, Hirvonen J, Elofsson M, Sandler N, Vuorela PM (2014) Inhibitory activity of the isoflavone biochanin A on intracellular bacteria of genus Chlamydia and initial development of a buccal formulation. PLoS One 9: e115115

Härtlova A, Link M, Balounova J, Benesova M, Resch U, Straskova A, Sobol M, Philimonenko A, Hozak P, Krocova Z, Gekara N, Filipp D, Stulik J (2014) Quantitative Proteomics Analysis of Macrophage-Derived Lipid Rafts Reveals Induction of Autophagy Pathway at the Early Time of Francisella tularensis LVS Infection. Journal of Proteome Research 13: 796-804

Hassan OA, Ahlm C, Evander M (2014) A need for One Health approach - lessons learned from outbreaks of Rift Valley fever in Saudi Arabia and Sudan. Infect Ecol Epidemiol 4: 1

Hogg M, Osterman P, Bylund GO, Ganai RA, Lundström E-B, Sauer-Eriksson AE, Johansson E (2014) Structural basis for processive DNA synthesis by yeast DNA polymerase epsilon. Nature Structural & Molecular Biology 21: 49-+

Horvath D, Lisurek M, Rupp B, Kuhne R, Specker E, von Kries J, Rognan D, Andersson CD, Almqvist F, Elofsson M, Enqvist PA, Gustavsson AL, Remez N, Mestres J, Marcou G, Varnek A, Hibert M, Quintana J, Frank R (2014) Design of a General-Purpose European Compound Screening Library for EU-OPENSCREEN. Chemmedchem 9: 2309-2326

Jinek M, Jiang F, Taylor DW, Sternberg SH, Kaya E, Ma E, Anders C, Hauer M, Zhou K, Lin S, Kaplan M, Iavarone AT, Charpentier E, Nogales E, Doudna JA (2014) Structures of Cas9 endonucleases reveal RNA-mediated conformational activation. Science 343: 1247997

Johansson A, Larkeryd A, Widerstrom M, Mortberg S, Myrtannas K, Ohrman C, Birdsell D, Keim P, Wagner DM, Forsman M, Larsson P (2014) An Outbreak of Respiratory Tularemia Caused by Diverse Clones of Francisella tularensis. Clinical Infectious Diseases 59: 1546-1553

Khalil H, Hornfeldt B, Evander M, Magnusson M, Olsson G, Ecke F (2014) Dynamics and Drivers of Hantavirus Prevalence in Rodent Populations. Vector-Borne Zoonotic Dis 14: 537-551

Khalil H, Olsson G, Ecke F, Evander M, Hjertqvist M, Magnusson M, Lofvenius MO, Hörnfeldt B (2014) The Importance of Bank Vole Density and Rainy Winters in Predicting Nephropathia Epidemica Incidence in Northern Sweden. Plos One 9: 7

Krishnamoorthy M, Hakobyan S, Ramstedt M, Gautrot JE (2014) Surface-Initiated Polymer Brushes in the Biomedical Field: Applications in Membrane Science, Biosensing, Cell Culture, Regenerative Medicine and Antibacterial Coatings. Chem Rev 114: 10976-11026

Kuzmenko A, Atkinson GC, Levitskii S, Zenkin N, Tenson T, Hauryliuk V, Kamenski P (2014) Mitochondrial translation initiation machinery: Conservation and diversification. Biochimie 100: 132-140

Larsson M, Caraballo R, Ericsson M, Lookene A, Enquist P-A, Elofsson M, Nilsson SK, Olivecrona G (2014) Identification of a small molecule that stabilizes lipoprotein lipase in vitro and lowers triglycerides in vivo. Biochemical and Biophysical Research Communications 450: 1063-1069

Latvala S, Makela SM, Miettinen M, Charpentier E, Julkunen I (2014) Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages. Clinical and Experimental Immunology 178: 320-333

Li X, Yang Q, Dierckens K, Milton DL, Defoirdt T (2014) RpoS and Indole Signaling Control the Virulence of Vibrio anguillarum towards Gnotobiotic Sea Bass (Dicentrarchus labrax) Larvae. Plos One 9: e111801

Li Y, Li L, Huang L, Francis MS, Hu Y, Chen S (2014) Yersinia Ysc-Yop type III secretion feedback inhibition is relieved through YscV-dependent recognition and secretion of LcrQ. Molecular Microbiology 91: 494-507

Lin CY, Wu MY, Gay S, Marjavaara L, Lai MS, Hsiao WC, Hung SH, Tseng HY, Wright DE, Wang CY, Hsu GSW, Devys D, Chabes A, Kao CF (2014) H2B Mono-ubiquitylation Facilitates Fork Stalling and Recovery during Replication Stress by Coordinating Rad53 Activation and Chromatin Assembly. PLoS genetics 10: 17

Lindgren AEG, Larsson A, Linusson A, Elofsson M (2014) Statistical molecular design: a tool to follow up hits from small-molecule screening. Methods in molecular biology (Clifton, NJ) 1056: 169-88

Lindgren M, Tancred L, Golovliov I, Conlan W, Twine SM, Sjöstedt A (2014) Identification of mechanisms for attenuation of the FSC043 mutant of Francisella tularensis SCHU S4. Infect Immun 82: 3622-3635

Lu P, Zhang Y, Hu Y, Francis MS, Chen S (2014) A cis-encoded sRNA controls the expression of fabH2 in Yersinia. Febs Letters 588: 1961-1966

Mahdavi J, Pirinccioglu N, Oldfield NJ, Carlsohn E, Stoof J, Aslam A, Self T, Cawthraw SA, Petrovska L, Colborne N, Sihlbom C, Borén T, Wooldridge KG, Ala'Aldeen DAA (2014) A novel O-linked glycan modulates Campylobacter jejuni major outer membrane protein-mediated adhesion to human histo-blood group antigens and chicken colonization. Open Biology 4: 130202

Marwaha S, Uvell H, Salin O, Lindgren AEG, Silver J, Elofsson M, Gylfe A (2014) N-Acylated Derivatives of Sulfamethoxazole and Sulfafurazole Inhibit Intracellular Growth of Chlamydia trachomatis. Antimicrobial Agents and Chemotherapy 58: 2968-2971

Messing J, Niehues M, Shevtsova A, Borén T, Hensel A (2014) Antiadhesive Properties of Arabinogalactan Protein from Ribes nigrum Seeds against Bacterial Adhesion of Helicobacter pylori. Molecules 19: 3696-3717

Messing J, Thoele C, Niehues M, Shevtsova A, Glocker E, Borén T, Hensel A (2014) Antiadhesive Properties of Abelmoschus esculentus (Okra) Immature Fruit Extract against Helicobacter pylori Adhesion. Plos One 9: e84836

Moll A, Dorr T, Alvarez L, Chao MC, Davis BM, Cava F, Waldor MK (2014) Cell Separation in Vibrio cholerae Is Mediated by a Single Amidase Whose Action Is Modulated by Two Nonredundant Activators. Journal of Bacteriology 196: 3937-3948

Nasstrom E, Thieu NTV, Dongol S, Karkey A, Vinh PV, Thanh TH, Johansson A, Arjyal A, Thwaites G, Dolecek C, Basnyat B, Baker S, Antti H (2014) Salmonella Typhi and Salmonella Paratyphi A elaborate distinct systemic metabolite signatures during enteric fever. Elife 3

Normark J, Nelson M, Engström P, Andersson M, Björk R, Moritz T, Fahlgren A, Bergström S (2014) Maladjusted Host Immune Responses Induce Experimental Cerebral Malaria-Like Pathology in a Murine Borrelia and Plasmodium Co-Infection Model. Plos One 9: 11

Olofsson A, Skalman LN, Obi I, Lundmark R, Arnqvist A (2014) Uptake of Helicobacter pylori Vesicles Is Facilitated by Clathrin-Dependent and Clathrin-Independent Endocytic Pathways. Mbio 5: e00979-14

Överby A, Nilsson E (2014) Det tidiga immunförsvaret nyckel i kampen mot TBE-virus. Neurologi i Sverige 2: 68-74

Parkinson AJ, Evengard B, Semenza JC, Ogden N, Borresen ML, Berner J, Brubaker M, Sjöstedt A, Evander M, Hondula DM, Menne B, Pshenichnaya N, Gounder P, Larose T, Revich B, Hueffer K, Albihn A (2014) Climate change and infectious diseases in the Arctic: establishment of a circumpolar working group. International journal of circumpolar health 73: 25163

Parreira P, Shi Q, Magalhaes A, Reis CA, Bugaytsova J, Borén T, Leckband D, Martins MCL (2014) Atomic force microscopy measurements reveal multiple bonds between Helicobacter pylori blood group antigen binding adhesin and Lewis b ligand. Journal of the Royal Society Interface 11: 20141040

Pettersson L, Thunberg T, Rocklöv J, Klingström J, Evander M, Ahlm C (2014) Viral load and humoral immune response in association with disease severity in Puumala hantavirus-infected patients-implications for treatment. Clin Microbiol Infect 20: 235-241

Ramstedt M, Leone L, Persson P, Shchukarev A (2014) Cell Wall Composition of Bacillus subtilis Changes as a Function of pH and Zn2+ Exposure: Insights from Cryo-XPS Measurements. Langmuir 30: 4367-4374

Röhm M, Grimm MJ, D'Auria AC, Almyroudis NG, Segal BH, Urban CF (2014) NADPH Oxidase Promotes Neutrophil Extracellular Trap Formation in Pulmonary Aspergillosis. Infection and Immunity 82: 1766-1777

Römling U, Kjelleberg S, Normark S, Nyman L, Uhlin BE, Akerlund B (2014) Microbial biofilm formation: a need to act. Journal of Internal Medicine 276: 98-110

Rubinstein L, Ungar L, Harari Y, Babin V, Ben-Aroya S, Merenyi G, Marjavaara L, Chabes A, Kupiec M (2014) Telomere length kinetics assay (TELKA) sorts the telomere length maintenance (tlm) mutants into functional groups. Nucleic Acids Research 42: 6314-6325

Rzhepishevska O, Hakobyan S, Ekstrand-Hammarstrom B, Nygren Y, Karlsson T, Bucht A, Elofsson M, Boily JF, Ramstedt M (2014) The gallium(III)-salicylidene acylhydrazide complex shows synergistic anti-biofilm effect and inhibits toxin production by Pseudomonas aeruginosa. Journal of Inorganic Biochemistry 138: 1-8

Sandholm K, Henningsson AJ, Save S, Bergström S, Forsberg P, Jonsson N, Ernerudh J, Ekdahl KN (2014) Early Cytokine Release in Response to Live Borrelia burgdorferi Sensu Lato Spirochetes Is Largely Complement Independent. Plos One 9: 9

Shah C, Hegde BG, Morén B, Behrmann E, Mielke T, Moenke G, Spahn CM, Lundmark R, Daumke O, Langen R (2014) Structural insights into membrane interaction and caveolar targeting of dynamin-like EHD2. Structure 22: 409-420

Song T, Sabharwal D, Gurung JM, Cheng AT, Sjöström AE, Yildiz FH, Uhlin BE, Wai SN (2014) Vibrio cholerae Utilizes Direct sRNA Regulation in Expression of a Biofilm Matrix Protein. Plos One 9: e101280

Sothiselvam S, Liu B, Han W, Ramu H, Klepacki D, Atkinson GC, Brauer A, Remm M, Tenson T, Schulten K, Vazquez-Laslop N, Mankin AS (2014) Macrolide antibiotics allosterically predispose the ribosome for translation arrest. Proceedings of the National Academy of Sciences of the United States of America 111: 9804-9809

Starosta AL, Lassak J, Peil L, Atkinson GC, Virumae K, Tenson T, Remme J, Jung K, Wilson DN (2014) Translational stalling at polyproline stretches is modulated by the sequence context upstream of the stall site. Nucleic Acids Research 42: 10711-10719

Starosta AL, Lassak J, Peil L, Atkinson GC, Woolstenhulme CJ, Virumae K, Buskirk A, Tenson T, Remme J, Jung K, Wilson DN (2014) A Conserved Proline Triplet in Val-tRNA Synthetase and the Origin of Elongation Factor P. Cell Reports 9: 476-483

Strand M, Carlsson M, Uvell H, Islam K, Edlund K, Cullman I, Altermark B, Mei YF, Elofsson M, Willassen NP, Wadell G, Almqvist F (2014) Isolation and Characterization of Anti-Adenoviral Secondary Metabolites from Marine Actinobacteria. Marine Drugs 12: 799-821

Stylianou M, Kulesskiy E, Lopes JP, Granlund M, Wennerberg K, Urban CF (2014) Antifungal Application of Nonantifungal Drugs. Antimicrobial Agents and Chemotherapy 58: 1055-1062

Subedi S, Moonens K, Romao E, Lo A, Vandenbussche G, Bugaytsova J, Muyldermans S, Borén T, Remaut H (2014) Expression, purification and X-ray crystallographic analysis of the Helicobacter pylori blood group antigen-binding adhesin BabA. Acta Crystallographica Section F-Structural Biology Communications 70: 1631-1635

Sun K, Broms J, Lavander M, Gurram BK, Enquist P-A, Andersson CD, Elofsson M, Sjostedt A (2014) Screening for Inhibition of Vibrio cholerae VipA-VipB Interaction Identifies Small-Molecule Compounds Active against Type VI Secretion. Antimicrobial Agents and Chemotherapy 58: 4123-4130

Sundqvist M, Granholm S, Naseer U, Ryden P, Brolund A, Sundsfjord A, Kahlmeter G, Johansson A (2014) Within-Population Distribution of Trimethoprim Resistance in Escherichia coli before and after a Community-Wide Intervention on Trimethoprim Use. Antimicrobial Agents and Chemotherapy 58: 7492-7500

Thay B, Damm A, Kufer TA, Wai SN, Oscarsson J (2014) Aggregatibacter actinomycetemcomitans Outer Membrane Vesicles Are Internalized in Human Host Cells and Trigger NOD1- and NOD2-Dependent NF-kappa B Activation. Infection and Immunity 82: 4034-4046

Toriola AT, Tolockiene E, Schock H, Surcel H-M, Zeleniuch-Jacquotte A, Wadell G, Toniolo P, Lundin E, Grankvist K, Lukanova A (2014) Free beta- human chorionic gonadotropin, total human chorionic gonadotropin and maternal risk of breast cancer. Future Oncology 10: 377-384

Upadhyay AS, Vonderstein K, Pichlmair A, Stehling O, Bennett KL, Dobler G, Guo J-T, Superti-Furga G, Lill R, Överby AK, Weber F (2014) Viperin is an iron-sulfur protein that inhibits genome synthesis of tick-borne encephalitis virus via radical SAM domain activity. Cellular Microbiology 16: 834-848

Wang J, Ehlers P, Silander I, Axner O (2014) On the accuracy of the assessment of molecular concentration and spectroscopic parameters by frequency modulation spectrometry and NICE-OHMS. Journal of Quantitative Spectroscopy & Radiative Transfer 136: 28-44

Weber E, Finsterbusch K, Lindquist R, Nair S, Lienenklaus S, Gekara NO, Janik D, Weiss S, Kalinke U, Överby AK, Kroeger A (2014) Type I Interferon Protects Mice from Fatal Neurotropic Infection with Langat Virus by Systemic and Local Antiviral Responses. Journal of Virology 88: 12202-12212

Weise CF, Login FH, Ho O, Grobner G, Wolf-Watz H, Wolf-Watz M (2014) Negatively charged lipid membranes promote a disorder-order transition in the Yersinia YscU protein. Biophys J 107: 1950-1961

Westberg J, Axner O (2014) Lineshape asymmetries in Faraday modulation spectroscopy. Applied Physics B-Lasers and Optics 116: 467-476

Westberg J, Wang JY, Axner O (2014) Methodology for fast curve fitting to modulated Voigt dispersion lineshape functions. Journal of Quantitative Spectroscopy & Radiative Transfer 133: 244-250

Westermark L, Fahlgren A, Fällman M (2014) Yersinia pseudotuberculosis Efficiently Escapes Polymorphonuclear Neutrophils during Early Infection. Infection and Immunity 82: 1181-1191

Wieser A, Storz E, Liegl G, Peter A, Pritsch M, Shock J, Wai SN, Schubert S (2014) Efficient quantification and characterization of bacterial outer membrane derived nano-particles with flow cytometric analysis. International Journal of Medical Microbiology 304: 1032-1037

Yamamoto S, Mitobe J, Ishikawa T, Wai SN, Ohnishi M, Watanabe H, Izumiya H (2014) Regulation of natural competence by the orphan two-component system sensor kinase ChiS involves a non-canonical transmembrane regulator in Vibrio cholerae. Molecular Microbiology 91: 326-347

Yang F, Korban SS, Pusey PL, Elofsson M, Sundin GW, Zhao Y (2014) Small-molecule inhibitors suppress the expression of both type III secretion and amylovoran biosynthesis genes in Erwinia amylovora. Molecular Plant Pathology 15: 44-57

Yoshida K, Bacal J, Desmarais D, Padioleau I, Tsaponina O, Chabes A, Pantesco V, Dubois E, Parrinello H, Skrzypczak M, Ginalski K, Lengronne A, Pasero P (2014) The Histone Deacetylases Sir2 and Rpd3 Act on Ribosomal DNA to Control the Replication Program in Budding Yeast. Molecular Cell 54: 691-697

Yu CH, Gan HY, Han JH, Zhou ZX, Jia SD, Chabes A, Farrugia G, Ordog T, Zhang ZG (2014) Strand-Specific Analysis Shows Protein Binding at Replication Forks and PCNA Unloading from Lagging Strands when Forks Stall. Molecular Cell 56: 551-563

Zocher G, Mistry N, Frank M, Haehnlein-Schick I, Ekström J-O, Arnberg N, Stehle T (2014) A Sialic Acid Binding Site in a Human Picornavirus. Plos Pathogens 10: e1004401

Publikationer 2013

Almyroudis NG, Grimm MJ, Davidson BA, Roehm M, Urban CF, Segal BH (2013) NETosis and NADPH oxidase: at the intersection of host defense, inflammation, and injury. Frontiers in Immunology 4: 45

Amer AA, Costa TR, Farag SI, Avican U, Forsberg Å, Francis MS (2013) Genetically engineered frameshifted YopN-TyeA chimeras influence type III secretion system function in Yersinia pseudotuberculosis. PLoS One 8: e77767

Andersson CD, Forsgren N, Akfur C, Allgardsson A, Berg L, Engdahl C, Qian WX, Ekstrom F, Linusson A (2013) Divergent Structure-Activity Relationships of Structurally Similar Acetylcholinesterase Inhibitors. J Med Chem 56: 7615-7624

Andersson EK, Bengtsson C, Evans ML, Chorell E, Sellstedt M, Lindgren AEG, Hufnagel DA, Bhattacharya M, Tessier PM, Wittung-Stafshede P, Almqvist F, Chapman MR (2013) Modulation of Curli Assembly and Pellicle Biofilm Formation by Chemical and Protein Chaperones. Chemistry & Biology 20: 1245-1254

Antti H, Fahlgren A, Näsström E, Kouremenos K, Sunden-Cullberg J, Guo Y, Moritz T, Wolf-Watz H, Johansson A, Fällman M (2013) Metabolic Profiling for Detection of Staphylococcus aureus Infection and Antibiotic Resistance. PLoS One 8: e56971

Arnberg N (2013) Adenovirus E3 protein modulates leukocyte functions. Proceedings of the National Academy of Sciences of the United States of America 110: 19976-19977

Artursson E, Andersson PO, Akfur C, Linusson A, Borjegren S, Ekström F (2013) Catalytic-site conformational equilibrium in nerve-agent adducts of acetylcholinesterase: Possible implications for the HI-6 antidote substrate specificity. Biochem Pharmacol 85: 1389-1397

Barcena-Uribarri I, Thein M, Maier E, Bonde M, Bergström S, Benz R (2013) Use of Nonelectrolytes Reveals the Channel Size and Oligomeric Constitution of the Borrelia burgdorferi P66 Porin. Plos One 8: 11

Bengtsson C, Nelander H, Almqvist F (2013) Asymmetric Synthesis of 2,4,5-Trisubstituted (2)-Thiazolines. Chemistry-a European Journal 19: 9916-9922

Bröms JE, Ishikawa T, Wai SN, Sjöstedt A (2013) A functional VipA-VipB interaction is required for the type VI secretion system activity of Vibrio cholerae O1 strain A1552. BMC Microbiol 13: 96

Byström J, Thomson SJ, Johansson J, Edin ML, Zeldin DC, Gilroy DW, Smith AM, Bishop-Bailey D (2013) Inducible CYP2J2 and Its Product 11,12-EET Promotes Bacterial Phagocytosis: A Role for CYP2J2 Deficiency in the Pathogenesis of Crohn's Disease? Plos One 8: e75107

Cava F, Kuru E, Brun YV, de Pedro MA (2013) Modes of cell wall growth differentiation in rod-shaped bacteria. Current Opinion in Microbiology 16: 731-737

Charpentier E, Doudna JA (2013) Biotechnology: Rewriting a genome. Nature 495: 50-51

Chung JCS, Rzhepishevska O, Ramstedt M, Welch M (2013) Type III secretion system expression in oxygen-limited Pseudomonas aeruginosa cultures is stimulated by isocitrate lyase activity. Open Biology 3: 11

Chylinski K, Le Rhun A, Charpentier E (2013) The tracrRNA and Cas9 families of type II CRISPR-Cas immunity systems. RNA Biol 10: 726-737

Cortese K, Howes MT, Lundmark R, Tagliatti E, Bagnato P, Petrelli A, Bono M, McMahon HT, Parton RG, Tacchetti C (2013) The HSP90 inhibitor geldanamycin perturbs endosomal structure and drives recycling ErbB2 and transferrin to modified MVBs/lysosomal compartments. Mol Biol Cell 24: 129-144

Costa TRD, Amer AAA, Farag SI, Wolf-Watz H, Fällman M, Fahlgren A, Edgren T, Francis MS (2013) Type III secretion translocon assemblies that attenuate Yersinia virulence. Cellular Microbiology 15: 1088-1110

Desmarais SM, De Pedro MA, Cava F, Huang KC (2013) Peptidoglycan at its peaks: how chromatographic analyses can reveal bacterial cell wall structure and assembly. Molecular Microbiology 89: 1-13

Doerr T, Cava F, Lam H, Davis BM, Waldor MK (2013) Substrate specificity of an elongation-specific peptidoglycan endopeptidase and its implications for cell wall architecture and growth of Vibrio cholerae. Molecular Microbiology 89: 949-962

Duperthuy M, Sjöström AE, Sabharwal D, Damghani F, Uhlin BE, Wai SN (2013) Role of the Vibrio cholerae Matrix Protein Bap1 in Cross-Resistance to Antimicrobial Peptides. Plos Pathogens 9: e1003620

Edwin A, Rompikuntal P, Björn E, Stier G, Wai SN, Sauer-Eriksson AE (2013) Calcium binding by the PKD1 domain regulates interdomain flexibility in Vibrio cholerae metalloprotease PrtV. Febs Open Bio 3: 263-270

Engstrom P, Nguyen BD, Normark J, Nilsson I, Bastidas RJ, Gylfe A, Elofsson M, Fields KA, Valdivia RH, Wolf-Watz H, Bergström S (2013) Mutations in hemG Mediate Resistance to Salicylidene Acylhydrazides, Demonstrating a Novel Link between Protoporphyrinogen Oxidase (HemG) and Chlamydia trachomatis Infectivity. Journal of Bacteriology 195: 4221-4230

Ermert D, Niemiec MJ, Rohm M, Glenthoj A, Borregaard N, Urban CF (2013) Candida albicans escapes from mouse neutrophils. Journal of Leukocyte Biology 94: 223-236

Francis MS (2013) The pathogenic Yersiniae-advances in the understanding of physiology and virulence. Frontiers in Cellular and Infection Microbiology 3: 51

Fuchino K, Bagchi S, Cantlay S, Sandblad L, Wu D, Bergman J, Kamali-Moghaddam M, Flardh K, Ausmees N (2013) Dynamic gradients of an intermediate filament-like cytoskeleton are recruited by a polarity landmark during apical growth. Proceedings of the National Academy of Sciences of the United States of America 110: E1889-E1897

Fuhrmann J, Mierzwa B, Trentini DB, Spiess S, Lehner A, Charpentier E, Clausen T (2013) Structural basis for recognizing phosphoarginine and evolving residue-specific protein phosphatases in gram-positive bacteria. Cell Rep 3: 1832-1839

Golovliov I, Twine SM, Shen H, Sjöstedt A, Conlan W (2013) A Delta clpB Mutant of Francisella tularensis Subspecies holarctica Strain, FSC200, Is a More Effective Live Vaccine than F. tularensis LVS in a Mouse Respiratory Challenge Model of Tularemia. Plos One 8: e78671

Greber UF, Arnberg N, Wadell G, Benko M, Kremer EJ (2013) Adenoviruses - from pathogens to therapeutics: a report on the 10th International Adenovirus Meeting. Cellular Microbiology 15: 16-23

Grimm MJ, Vethanayagam RR, Almyroudis NG, Dennis CG, Khan AN, D'Auria AC, Singel KL, Davidson BA, Knight PR, Blackwell TS, Hohl TM, Mansour MK, Vyas JM, Rohm M, Urban CF, Kelkka T, Holmdahl R, Segal BH (2013) Monocyte- and macrophage-targeted NADPH oxidase mediates antifungal host defense and regulation of acute inflammation in mice. J Immunol 190: 4175-4184

Gross J, Passmore I, Chung JS, Rzhepishevska O, Ramstedt M, Welch M (2013) Universal soldier: Pseudomonas aeruginosa — an opportunistic generalist. Front Biol 8: 387-394

Gupta A, Sharma S, Reichenbach P, Marjavaara L, Nilsson AK, Lingner J, Chabes A, Rothstein R, Chang M (2013) Telomere Length Homeostasis Responds to Changes in Intracellular dNTP Pools. Genetics 193(4):1095-105

Hedberg ME, Israelsson A, Moore ERB, Svensson-Stadler L, Wai SN, Pietz G, Sandström O, Hernell O, Hammarstrom M-L, Hammarstrom S (2013) Prevotella jejuni sp nov., isolated from the small intestine of a child with coeliac disease. International Journal of Systematic and Evolutionary Microbiology 63: 4218-4223

Hernandez J, Johansson A, Stedt J, Bengtsson S, Porczak A, Granholm S, Gonzalez-Acuna D, Olsen B, Bonnedahl J, Drobni M (2013) Characterization and Comparison of Extended-Spectrum beta-Lactamase (ESBL) Resistance Genotypes and Population Structure of Escherichia coli Isolated from Franklin's Gulls (Leucophaeus pipixcan) and Humans in Chile. Plos One ;8(9):e76150

Hoch NC, Chen ESW, Buckland R, Wang SC, Fazio A, Hammet A, Pellicioli A, Chabes A, Tsai MD, Heierhorst J (2013) Molecular Basis of the Essential S Phase Function of the Rad53 Checkpoint Kinase. Molecular and Cellular Biology 33: 3202-3213

Horvath I, Sellstedt M, Weise C, Nordvall LM, Prasad GK, Olofsson A, Larsson G, Almqvist F, Wittung-Stafshede P (2013) Modulation of alpha-synuclein fibrillization by ring-fused 2-pyridones: Templation and inhibition involve oligomers with different structure. Archives of Biochemistry and Biophysics 532: 84-90

Hosseinzadeh A, Urban CF (2013) Novel insight into neutrophil immune responses by dry mass determination of Candida albicans morphotypes. PLoS One 8: e77993

Hussain M, Banchelin TSL, Andersson H, Olsson R, Almqvist F (2013) Enantioselective Synthesis of Substituted Piperidines by Addition of Aryl Grignard Reagents to Pyridine N-Oxides. Organic Letters 15: 54-57

Ito Y, Vela JL, Matsumura F, Hoshino H, Tyznik A, Lee H, Girardi E, Zajonc DM, Liddington R, Kobayashi M, Bao XF, Bugaytsova J, Borén T, Jin RS, Zong YN, Seeberger PH, Nakayama J, Kronenberg M, Fukuda M (2013) Helicobacter pylori Cholesteryl alpha-Glucosides Contribute to Its Pathogenicity and Immune Response by Natural Killer T Cells. Plos One 8: 12

Karlsson E, Svensson K, Lindgren P, Bystrom M, Sjodin A, Forsman M, Johansson A (2013) The phylogeographic pattern of Francisella tularensis in Sweden indicates a Scandinavian origin of Eurosiberian tularaemia. Environmental Microbiology 15: 634-645

Krishnan KS, Bengtsson C, Good JAD, Mirkhanov S, Chorell E, Johansson LBA, Almqvist F (2013) Synthesis of Fluorescent Ring-Fused 2-Pyridone Peptidomimetics. Journal of Organic Chemistry 78: 12207-12213

Lampe EO, Zingmark C, Hemnann L, Brudal E, Rishovd AL, Bröms J, Hagedorn M, Griffiths GW, Sjöstedt A, Winther-Larsen HC (2013) A study of virulence factors in the fish pathogen F. noatunensis ssp noatunensis. Fish Shellfish Immun 34: 1716-1716

Larsson M, Mishra BK, Tysklind M, Linusson A, Andersson PL (2013) On the use of electronic descriptors for QSAR modelling of PCDDs, PCDFs and dioxin-like PCBs() pound. Sar and Qsar in Environmental Research 24: 727-745

Lindgren AEG, Karlberg T, Ekblad T, Spjut S, Thorsell AG, Andersson CD, Nhan TT, Hellsten V, Weigelt J, Linusson A, Schuler H, Elofsson M (2013) Chemical Probes to Study ADP-Ribosylation: Synthesis and Biochemical Evaluation of Inhibitors of the Human ADP-Ribosyltransferase ARTD3/PARP3. J Med Chem 56: 9556-9568

Lindgren AEG, Karlberg T, Thorsell AG, Hesse M, Spjut S, Ekblad T, Andersson CD, Pinto AF, Weigelt J, Hottiger MO, Linusson A, Elofsson M, Schuler H (2013) PARP Inhibitor with Selectivity Toward ADP-Ribosyltransferase ARTD3/PARP3. Acs Chemical Biology 8: 1698-1703

Lindgren M, Bröms JE, Meyer L, Golovliov I, Sjöstedt A (2013) The Francisella tularensis LVS DeltapdpC mutant exhibits a unique phenotype during intracellular infection. BMC Microbiol 13: 20

Lindgren M, Eneslätt K, Broms JE, Sjöstedt A (2013) Importance of PdpC, IglC, IglI, and IglG for Modulation of a Host Cell Death Pathway Induced by Francisella tularensis. Infection and Immunity 81: 2076-2084

Lundström JO SM, Hesson JC, Blomgren E, Lindström A, Wahlqvist P, Halling A, Hagelin A, Ahlm C, Evander M, Broman T, Forsman M, Persson Vinnersten TZ. (2013) The geographic distribution of mosquito species in Sweden. Journal of the European Mosquito Control Association 31: 21-35

Mahdavi J, Royer P-J, Sjolinder HS, Azimi S, Self T, Stoof J, Wheldon LM, Brannström K, Wilson R, Moreton J, Moir JWB, Sihlbom C, Borén T, Jonsson A-B, Soultanas P, Ala'Aldeen DAA (2013) Pro-inflammatory cytokines can act as intracellular modulators of commensal bacterial virulence. Open Biology 3: 130048

Mellin JR, Tiensuu T, Becavin C, Gouin E, Johansson J, Cossart P (2013) A riboswitch-regulated antisense RNA in Listeria monocytogenes. Proc Natl Acad Sci U S A 110: 13132-13137

Mohamed N, Nilsson E, Johansson P, Klingstrom J, Evander M, Ahlm C, Bucht G (2013) Development and evaluation of a broad reacting SYBR-green based quantitative real-time PCR for the detection of different hantaviruses. J Clin Virol 56: 280-285

Mortezaei N, Singh B, Bullitt E, Uhlin BE, Andersson M (2013) P-fimbriae in the presence of anti-PapA antibodies: new insight of antibodies action against pathogens. Sci Rep 3: 3393

Norregaard K, Andersson M, Sneppen K, Nielsen PE, Brown S, Oddershede LB (2013) DNA supercoiling enhances cooperativity and efficiency of an epigenetic switch. Proceedings of the National Academy of Sciences of the United States of America 110: 17386-17391

Nylander A, Svensater G, Senadheera DB, Cvitkovitch DG, Davies JR, Persson K (2013) Structural and Functional Analysis of the N-terminal Domain of the Streptococcus gordonii Adhesin Sgo0707. Plos One 8: 12

Obi IR, Francis MS (2013) Demarcating SurA Activities Required for Outer Membrane Targeting of Yersinia pseudotuberculosis Adhesins. Infection and Immunity 81: 2296-2308

Palm-Espling ME, Andersson CD, Bjorn E, Linusson A, Wittung-Stafshede P (2013) Determinants for Simultaneous Binding of Copper and Platinum to Human Chaperone Atox1: Hitchhiking not Hijacking. Plos One 8: 12

Parreira P, Magalhaes A, Reis CA, Borén T, Leckband D, Martins MCL (2013) Bioengineered surfaces promote specific protein-glycan mediated binding of the gastric pathogen Helicobacter pylori. Acta Biomaterialia 9: 8885-8893

Poulsen HO, Johansson A, Granholm S, Kahlmeter G, Sundqvist M (2013) High genetic diversity of nitrofurantoin- or mecillinam-resistant Escherichia coli indicates low propensity for clonal spread. Journal of Antimicrobial Chemotherapy 68: 1974-1977

Roehm M, Lindemann E, Hiller E, Ermert D, Lemuth K, Trkulja D, Sogukpinar O, Brunner H, Rupp S, Urban CF, Sohn K (2013) A family of secreted pathogenesis-related proteins in Candida albicans. Molecular Microbiology 87: 132-151

Russell AB, LeRoux M, Hathazi K, Agnello DM, Ishikawa T, Wiggins PA, Wai SN, Mougous JD (2013) Diverse type VI secretion phospholipases are functionally plastic antibacterial effectors. Nature 496: 508-512

Ryden P, Twine S, Shen H, Harris G, Chen W, Sjöstedt A, Conlan W (2013) Correlates of protection following vaccination of mice with gene deletion mutants of Francisella tularensis subspecies tularensis strain, SCHU S4 that elicit varying degrees of immunity to systemic and respiratory challenge with wild-type bacteria. Molecular Immunology 54: 58-67

Rzhepishevska O, Hakobyan S, Ruhal R, Gautrot J, Barbero D, Ramstedt M (2013) The surface charge of anti-bacterial coatings alters motility and biofilm architecture. Biomaterials Science 1: 589-602

Salzer J, Hallmans G, Nystrom M, Stenlund H, Wadell G, Sundström P (2013) Smoking as a risk factor for multiple sclerosis. Multiple Sclerosis Journal 19: 1022-1027

Salzer J, Hallmans G, Nyström M, Stenlund H, Wadell G, Sundström P (2013) Vitamin A and systemic inflammation as protective factors in multiple sclerosis. Multiple Sclerosis Journal 19: 1046-1051

Salzer J, Nystrom M, Hallmans G, Stenlund H, Wadell G, Sundström P (2013) Epstein-Barr virus antibodies and vitamin D in prospective multiple sclerosis biobank samples. Multiple Sclerosis Journal 19: 1587-1591

Sellstedt M, Dang HT, Prasad GK, Sauer U, Almqvist F (2013) Four-Component Assembly of Natural-Product-Like Ring-Fused Isoquinuclidines. European Journal of Organic Chemistry 2013: 7476-7479

Seper A, Hosseinzadeh A, Gorkiewicz G, Lichtenegger S, Roier S, Leitner DR, Rohm M, Grutsch A, Reidl J, Urban CF, Schild S (2013) Vibrio cholerae Evades Neutrophil Extracellular Traps by the Activity of Two Extracellular Nucleases. Plos Pathogens 9: e1003614

Siegrist MS, Whiteside S, Jewett JC, Aditham A, Cava F, Bertozzi CR (2013) D-Amino Acid Chemical Reporters Reveal Peptidoglycan Dynamics of an Intracellular Pathogen. Acs Chemical Biology 8: 500-505

Silander I, Zelan M, Axner O, Arrhen F, Pendrill L, Foltynowicz A (2013) Optical measurement of the gas number density in a Fabry-Perot cavity. Measurement Science and Technology 24: 5

Tan KY, Lin H, Ramstedt M, Watt FM, Huck WTS, Gautrot JE (2013) Decoupling geometrical and chemical cues directing epidermal stem cell fate on polymer brush-based cell micro-patterns. Integr Biol 5: 899-910

Thay B, Wai SN, Oscarsson J (2013) Staphylococcus aureus alpha-Toxin-Dependent Induction of Host Cell Death by Membrane-Derived Vesicles. Plos One 8: e54661

Thorslund SE, Ermert D, Fahlgren A, Erttmann SF, Nilsson K, Hosseinzadeh A, Urban CF, Fällman M (2013) Role of YopK in Yersinia pseudotuberculosis Resistance against Polymorphonuclear Leukocyte Defense. Infection and Immunity 81: 11-22

Tiensuu T, Andersson C, Ryden P, Johansson J (2013) Cycles of light and dark co-ordinate reversible colony differentiation in Listeria monocytogenes. Molecular Microbiology 87: 909-924

Tsaponina O, Chabes A (2013) Pre-activation of the genome integrity checkpoint increases DNA damage tolerance. Nucleic Acids Research 41: 10371-10378

Tukenmez H, Chen C, Tsaponina O, Chabes A, Byström A (2013) Elongator complex enhances Rnr1 induction in response to DNA damage by promoting Ixr1 expression. Yeast 30: 106-106

Upadhyay AS, Vonderstein K, Pichlmair A, Stehling O, Guo J-T, Lill R, Weber F, Överby AK (2013) Viperin vs. tick-borne encephalitis virus: Mechanisms of a potent antiviral protein. Cytokine 63: 305-305

Vonkavaara M, Pavel STI, Holzl K, Nordfelth R, Sjöstedt A, Stoven S (2013) Francisella Is Sensitive to Insect Antimicrobial Peptides. Journal of Innate Immunity 5: 50-59

Wasserstrom S, Grantcharova N, Ubhayasekera W, Ausmees N, Sandblad L, Flardh K (2013) Non-sporulating ftsZ mutants in Streptomyces coelicolor reveal amino acid residues critical for FtsZ polymerization dynamics. Microbiol-Sgm 159: 890-901

Weber E, Finsterbusch K, Lindquist R, Kröger A, Överby A (2013) Type I interferon protects against lethal Langat virus infection. Cytokine 63: 308-308

Williams JS, Smith DJ, Marjavaara L, Lujan SA, Chabes A, Kunkel TA (2013) Topoisomerase 1-Mediated Removal of Ribonucleotides from Nascent Leading-Strand DNA. Molecular Cell 49: 1010-1015

Zakrisson J, Wiklund K, Axner O, Andersson M (2013) The Shaft of the Type 1 Fimbriae Regulates an External Force to Match the FimH Catch Bond. Biophysical Journal 104: 2137-2148

Zetterström CE, Hasselgren J, Salin O, Davis RA, Quinn RJ, Sundin C, Elofsson M (2013) The Resveratrol Tetramer (-)- Hopeaphenol Inhibits Type III Secretion in the Gram-Negative Pathogens Yersinia pseudotuberculosis and Pseudomonas aeruginosa. Plos One 8(12): e81969

Publikationer 2012

Achouiti A, Vogl T, Urban CF, Röhm M, Hommes TJ, van Zoelen MA, Florquin S, Roth J, van 't Veer C, de Vos AF, van der Poll T (2012) Myeloid-related protein-14 contributes to protective immunity in gram-negative pneumonia derived sepsis. PLoS Pathog 8: e1002987

Ahlinder J, Ohrman C, Svensson K, Lindgren P, Johansson A, Forsman M, Larsson P, Sjodin A (2012) Increased knowledge of Francisella genus diversity highlights the benefits of optimised DNA-based assays. BMC Microbiology 12:220

Andersson CD, Karlberg T, Ekblad T, Lindgren AEG, Thorsell AG, Spjut S, Uciechowska U, Niemiec MS, Wittung-Stafshede P, Weigelt J, Elofsson M, Schuler H, Linusson A (2012) Discovery of Ligands for ADP-Ribosyltransferases via Docking-Based Virtual Screening. J Med Chem 55: 7706-7718

Andersson M, Bjornham O, Svantesson M, Badandah A, Uhlin BE, Bullitt E (2012) A Structural Basis for Sustained Bacterial Adhesion: Biomechanical Properties of CFA/I Pili. Journal of Molecular Biology 415: 918-928

Arnberg N (2012) Adenovirus receptors: implications for targeting of viral vectors. Trends in Pharmacological Sciences 33: 442-448

Balonova L, Mann BF, Cerveny L, Alley WR, Chovancova E, Forslund AL, Salomonsson EN, Forsberg Å, Damborsky J, Novotny MV, Hernychova L, Stulik J (2012) Characterization of Protein Glycosylation in Francisella tularensis subsp holarctica. Molecular & Cellular Proteomics 11: M111.05016.

Barzegar HR, Nitze F, Sharifi T, Ramstedt M, Tai CW, Malolepszy A, Stobinski L, Wagberg T (2012) Simple Dip-Coating Process for the Synthesis of Small Diameter Single-Walled Carbon Nanotubes-Effect of Catalyst Composition and Catalyst Particle Size on Chirality and Diameter. J Phys Chem C 116: 12232-12239

Bengtsson C, Lindgren AEG, Uvell H, Almqvist F (2012) Design, synthesis and evaluation of triazole functionalized ring-fused 2-pyridones as antibacterial agents. European Journal of Medicinal Chemistry 54: 637-646

Berg L, Niemiec MS, Qian WX, Andersson CD, Wittung-Stafshede P, Ekström F, Linusson A (2012) Similar but Different: Thermodynamic and Structural Characterization of a Pair of Enantiomers Binding to Acetylcholinesterase. Angew Chem-Int Edit 51: 12716-12720

Bjarnsholt T, Hoiby N, Donelli G, Imbert C, Forsberg Å (2012) Understanding biofilms--are we there yet? FEMS Immunol Med Microbiol 65: 125-126

Böhme K, Steinmann R, Kortmann J, Seekircher S, Heroven AK, Berger E, Pisano F, Thiermann T, Wolf-Watz H, Narberhaus F, Dersch P (2012) Concerted actions of a thermo-labile regulator and a unique intergenic RNA thermosensor control Yersinia virulence. PLoS Pathog 8: e1002518

Bröms JE, Meyer L, Lavander M, Larsson P, Sjöstedt A (2012) DotU and VgrG, core components of type VI secretion systems, are essential for Francisella LVS pathogenicity. PLoS One 7: e34639

Bröms JE, Meyer L, Sun K, Lavander M, Sjöstedt A (2012) Unique substrates secreted by the type VI secretion system of Francisella tularensis during intramacrophage infection. PLoS One 7: e50473

Chorell E, Pinkner JS, Bengtsson C, Banchelin TSL, Edvinsson S, Linusson A, Hultgren SJ, Almqvist F (2012) Mapping pilicide anti-virulence effect in Escherichia coli, a comprehensive structure-activity study. Bioorganic & Medicinal Chemistry 20: 3128-3142

Chorell E, Pinkner JS, Bengtsson C, Edvinsson S, Cusumano CK, Rosenbaum E, Johansson LBA, Hultgren SJ, Almqvist F (2012) Design and Synthesis of Fluorescent Pilicides and Curlicides: Bioactive Tools to Study Bacterial Virulence Mechanisms. Chemistry-a European Journal 18: 4522-4532

Collin B, Rehnstam-Holm AS, Lindmark B, Pal A, Wai SN, Hernroth B (2012) The origin of Vibrio cholerae influences uptake and persistence in the blue mussel Mytilus edulis Journal of Shellfish Research 31: 87-92

Costa TRD, Amer AAA, Fällman M, Fahlgren A, Francis MS (2012) Coiled-coils in the YopD translocator family: A predicted structure unique to the YopD N-terminus contributes to full virulence of Yersinia pseudotuberculosis. Infection Genetics and Evolution 12: 1729-1742

Davidson MB, Katou Y, Keszthelyi A, Sing TL, Xia T, Ou JW, Vaisica JA, Thevakumaran N, Marjavaara L, Myers CL, Chabes A, Shirahige K, Brown GW (2012) Endogenous DNA replication stress results in expansion of dNTP pools and a mutator phenotype. Embo Journal 31: 895-907

Dicks MDJ, Spencer AJ, Edwards NJ, Wadell G, Bojang K, Gilbert SC, Hill AVS, Cottingham MG (2012) A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity. Plos One 7: e40385

Edgren T, Forsberg Å, Rosqvist R, Wolf-Watz H (2012) Type III secretion in Yersinia: injectisome or not? PLoS Pathog 8: e1002669

Ehlers P, Silander I, Wang J, Axner O (2012) Fiber-laser-based noise-immune cavity-enhanced optical heterodyne molecular spectrometry instrumentation for Doppler-broadened detection in the 10(-12) cm(-1) Hz(-1/2) region. Journal of the Optical Society of America B-Optical Physics 29: 1305-1315

Elbir H, Gimenez G, Robert C, Bergström S, Cutler S, Raoult D, Drancourt M (2012) Complete Genome Sequence of Borrelia crocidurae. Journal of Bacteriology 194: 3723-3724

Eneslatt K, Normark M, Bjork R, Rietz C, Zingmark C, Wolfraim LA, Stoven S, Sjostedt A (2012) Signatures of T Cells as Correlates of Immunity to Francisella tularensis. Plos One 7: e32367

Enquist PA, Gylfe A, Hagglund U, Lindstom P, Norberg-Scherman H, Sundin C, Elofsson M (2012) Derivatives of 8-hydroxyquinoline-antibacterial agents that target intra- and extracellular Gram-negative pathogens. Bioorganic & Medicinal Chemistry Letters 22: 3550-3553

Eriksson J, Grundström C, Sauer-Eriksson AE, Sauer UH, Wolf-Watz H, Elofsson M (2012) Small molecule screening for inhibitors of the YopH phosphatase of Yersinia pseudotuberculosis. Adv Exp Med Biol 954: 357-363

Fineran PC, Charpentier E (2012) Memory of viral infections by CRISPR-Cas adaptive immune systems: acquisition of new information. Virology 434: 202-209

Forthal DN, Phan TB, Slepenkin AV, Landucci G, Chu H, Elofsson M, Peterson E (2012) In vitro anti-HIV-1 activity of salicylidene acylhydrazide compounds. International journal of antimicrobial agents 40: 354-360

Frost S, Ho O, Login FH, Weise CF, Wolf-Watz H, Wolf-Watz M (2012) Autoproteolysis and intramolecular dissociation of Yersinia YscU precedes secretion of its C-terminal polypeptide YscU(CC). PLoS One 7: e49349

Gabrielsen M, Beckham KSH, Feher VA, Zetterstrom CE, Wang D, Muller S, Elofsson M, Amaro RE, Byron O, Roe AJ (2012) Structural Characterisation of Tpx from Yersinia pseudotuberculosis Reveals Insights into the Binding of Salicylidene Acylhydrazide Compounds. Plos One 7: e32217

Garcia-Aljaro C, Melado-Rovira S, Milton DL, Blanch AR (2012) Quorum-sensing regulates biofilm formation in Vibrio scophthalmi. Bmc Microbiology 12: 287

Gyuranecz M, Birdsell DN, Splettstoesser W, Seibold E, Beckstrom-Sternberg SM, Makrai L, Fodor L, Fabbi M, Vicari N, Johansson A, Busch JD, Vogler AJ, Keim P, Wagner DM (2012) Phylogeography of Francisella tularensis subsp holarctica, Europe. Emerging Infectious Diseases 18: 290-293

Hammer ND, McGuffie BA, Zhou YZ, Badtke MP, Reinke AA, Brannstrom K, Gestwicki JE, Olofsson A, Almqvist F, Chapman MR (2012) The C-Terminal Repeating Units of CsgB Direct Bacterial Functional Amyloid Nucleation. Journal of Molecular Biology 422: 376-389

Hedberg ME, Moore ERB, Svensson-Stadler L, Horstedt P, Baranoy V, Hernell O, Wai SN, Hammarstrom S, Hammarstrom ML (2012). Lachnoanaerobaculum gen. nov., a new genus in the Lachnospiraceae: characterization of Lachnoanaerobaculum umeaense gen. nov., sp nov., isolated from the human small intestine, and Lachnoanaerobaculum orale sp nov., isolated from saliva, and reclassification of Eubacterium saburreum (Prevot 1966) Holdeman and Moore 1970 as Lachnoanaerobaculum saburreum comb. nov. International Journal of Systematic and Evolutionary Microbiology 62: 2685-2690

Hillgren JM, Öberg CT, Elofsson M (2012) Syntheses of pseudoceramines A-D and a new synthesis of spermatinamine, bromotyrosine natural products from marine sponges. Organic & Biomolecular Chemistry 10: 1246-1254

Hogg M, Sauer-Eriksson AE, Johansson E (2012) Promiscuous DNA synthesis by human DNA polymerase theta. Nucleic Acids Research 40: 2611-2622

Honn M, Lindgren H, Sjöstedt A (2012) The role of MglA for adaptation to oxidative stress of Francisella tularensis LVS. BMC Microbiology 12: 14

Horvath I, Weise CF, Andersson EK, Chorell E, Sellstedt M, Bengtsson C, Olofsson A, Hultgren SJ, Chapman M, Wolf-Watz M, Almqvist F, Wittung-Stafshede P (2012) Mechanisms of Protein Oligomerization: Inhibitor of Functional Amyloids Templates alpha-Synuclein Fibrillation. Journal of the American Chemical Society 134: 3439-3444

Hosseinzadeh A, Messer PK, Urban CF (2012) Stable Redox-Cycling Nitroxide Tempol Inhibits NET Formation. Front Immunol 3: 391

Ishikawa T, Sabharwal D, Bröms J, Milton DL, Sjostedt A, Uhlin BE, Wai SN (2012) Pathoadaptive Conditional Regulation of the Type VI Secretion System in Vibrio cholerae O1 Strains. Infection and Immunity 80: 575-584

Ito Y, Vela JL, Matsumura F, Hoshino H, Tyznik A, Lee H, Girardi E, Zajonc DM, Kobayashi M, Bao X, Borén T, Jin R, Seeberger PH, Nakayama J, Kronenberg M, Fukuda M (2012) Helicobacter pylori cholesteryl alpha-glucosides are critical for bacterial growthand activation of invariant NKT cells. Glycobiology 22: 1635-1636

Jinek M, Chylinski K, Fonfara I, Hauer M, Doudna JA, Charpentier E (2012) A Programmable Dual-RNA-Guided DNA Endonuclease in Adaptive Bacterial Immunity. Science 337: 816-821

Klinth JE, Castelain M, Uhlin BE, Axner O (2012) The Influence of pH on the Specific Adhesion of P Piliated Escherichia coli. Plos One 7: 8

Klinth JE, Pinkner JS, Hultgren SJ, Almqvist F, Uhlin BE, Axner O (2012) Impairment of the biomechanical compliance of P pili: a novel means of inhibiting uropathogenic bacterial infections? European Biophysics Journal with Biophysics Letters 41: 285-295

Landstrom J, Persson K, Rademacher C, Lundborg M, Wakarchuk W, Peters T, Widmalm G (2012) Small molecules containing hetero-bicyclic ring systems compete with UDP-Glc for binding to WaaG glycosyltransferase. Glycoconjugate J 29: 491-502

Le Rhun A, Charpentier E (2012) Small RNAs in streptococci. RNA Biology 9: 414-426

Lindell K, Fahlgren A, Hjerde E, Willassen NP, Fällman M, Milton DL (2012) Lipopolysaccharide O-antigen prevents phagocytosis of Vibrio anguillarum by rainbow trout (Oncorhynchus mykiss) skin epithelial cells. PLoS One 7: e37678

Liu J, Thanikkal EJ, Obi IR, Francis MS (2012) Elevated CpxR similar to P levels repress the Ysc-Yop type III secretion system of Yersinia pseudotuberculosis. Research in Microbiology 163: 518-530

Loh E, Memarpour F, Vaitkevicius K, Kallipolitis BH, Johansson J, Sonden B (2012) An unstructured 5'-coding region of the prfA mRNA is required for efficient translation. Nucleic Acids Research 40: 1818-1827

Meinzer U, Barreau F, Esmiol-Welterlin S, Jung C, Villard C, Leger T, Ben-Mkaddem S, Berrebi D, Dussaillant M, Alnabhani Z, Roy M, Bonacorsi S, Wolf-Watz H, Perroy J, Ollendorff V, Hugot JP (2012) Yersinia pseudotuberculosis effector YopJ subverts the Nod2/RICK/TAK1 pathway and activates caspase-1 to induce intestinal barrier dysfunction. Cell Host Microbe 11: 337-51

Moren B, Shah C, Howes MT, Schieber NL, McMahon HT, Parton RG, Daumke O, Lundmark R (2012) EHD2 regulates caveolar dynamics via ATP-driven targeting and oligomerization. Molecular Biology of the Cell 23: 1316-1329

Nakao R, Ramstedt M, Wai SN, Uhlin BE (2012) Enhanced biofilm formation by Escherichia coli LPS mutants defective in Hep biosynthesis. PLoS One 7: e51241

Napier BA, Meyer L, Bina JE, Miller MA, Sjöstedt A, Weiss DS (2012) Link between intraphagosomal biotin and rapid phagosomal escape in Francisella. Proceedings of the National Academy of Sciences of the United States of America 109: 18084-18089

Netterling S, Vaitkevicius K, Nord S, Johansson J (2012) A Listeria monocytogenes RNA helicase essential for growth and ribosomal maturation at low temperatures Uses Its C terminus for appropriate interaction with the ribosome. J Bacteriol 194: 4377-4385

Neu U, Hengel H, Blaum BS, Schowalter RM, Macejak D, Gilbert M, Wakarchuk WW, Imamura A, Ando H, Kiso M, Arnberg N, Garcea RL, Peters T, Buck CB, Stehle T (2012) Structures of Merkel Cell Polyomavirus VP1 Complexes Define a Sialic Acid Binding Site Required for Infection. Plos Pathogens 8: e1002738

Öberg CT, Strand M, Andersson EK, Edlund K, Nam Phuong Nguyen T, Mei Y-F, Wadell G, Elofsson M (2012) Synthesis, Biological Evaluation, and Structure-Activity Relationships of 2 2-(Benzoylamino)benzoylamino benzoic Acid Analogues as Inhibitors of Adenovirus Replication. J Med Chem 55: 3170-3181

Paracuellos P, Öhman A, Sauer-Eriksson AE, Uhlin BE (2012) Expression and purification of SfaX(II), a protein involved in regulating adhesion and motility genes in extraintestinal pathogenic Escherichia coli. Protein Expression and Purification 86: 127-134

Persson K, Esberg A, Claesson R, Stromberg N (2012) The Pilin Protein FimP from Actinomyces oris: Crystal Structure and Sequence Analyses. Plos One 7: 10

Pohjala L, Uvell H, Hakala E, Gylfe A, Elofsson M, Vuorela P (2012) The isoflavone biochanin a inhibits the growth of the intracellular bacteria Chiamydia trachomatis and Chlamydia pneumoniae. Planta Medica 78: 1102-1102

Poli J, Tsaponina O, Crabbe L, Keszthelyi A, Pantesco V, Chabes A, Lengronne A, Pasero P (2012) dNTP pools determine fork progression and origin usage under replication stress. Embo Journal 31: 883-894

Revill J, Carnevali MD, Forsberg Å, Holmstrom A, Rath J, Shinwari ZK, Mancini GM (2012) Lessons learned from implementing education on dual-use in Austria, Italy, Pakistan and Sweden. Med Confl Surviv 28: 31-44

Rompikuntal PK, Thay B, Khan MK, Alanko J, Penttinen A-M, Asikainen S, Wai SN, Oscarsson J (2012) Perinuclear Localization of Internalized Outer Membrane Vesicles Carrying Active Cytolethal Distending Toxin from Aggregatibacter actinomycetemcomitans. Infection and Immunity 80: 31-42

Ryden P, Bjork R, Schafer ML, Lundstrom JO, Petersen B, Lindblom A, Forsman M, Sjöstedt A, Johansson A (2012) Outbreaks of Tularemia in a Boreal Forest Region Depends on Mosquito Prevalence. Journal of Infectious Diseases 205: 297-304

Salzer J, Hallmans G, Nystrom M, Stenlund H, Wadell G, Sundstrom P (2012) Vitamin D as a protective factor in multiple sclerosis. Neurology 79: 2140-2145

Sanchez A, Sharma S, Rozenzhak S, Roguev A, Krogan NJ, Chabes A, Russell P (2012) Replication Fork Collapse and Genome Instability in a Deoxycytidylate Deaminase Mutant. Molecular and Cellular Biology 32: 4445-4454

Sandholm K, Henningsson AJ, Bergström S, Ernerudh J, Ekdahl KN (2012) Complement activation and phagocytosis in vitro of two strains of Borrelia burgdorferi S.L. Immunobiology 217: 1153-1153

Sellstedt M, Prasad GK, Krishnan KS, Almqvist F (2012) Directed diversity-oriented synthesis. Ring-fused 5-to 10-membered rings from a common peptidomimetic 2-pyridone precursor. Tetrahedron Letters 53: 6022-6024

Silander I, Ehlers P, Wang J, Axner O (2012) Frequency modulation background signals from fiber-based electro optic modulators are caused by crosstalk. Journal of the Optical Society of America B-Optical Physics 29: 916-923

Skogman BH, Hellberg S, Ekerfelt C, Jenmalm MC, Forsberg P, Ludvigsson J, Bergström S, Ernerudh J (2012) Adaptive and Innate Immune Responsiveness to Borrelia burgdorferi sensu lato in Exposed Asymptomatic Children and Children with Previous Clinical Lyme Borreliosis. Clin Dev Immunol 2012: 10

Strand M, Islam K, Edlund K, Öberg CT, Allard A, Bergstrom T, Mei Y-F, Elofsson M, Wadell G (2012) 2- 4,5-Difluoro-2-(2-Fluorobenzoylamino)-Benzoylamino Benzoic Acid, an Antiviral Compound with Activity against Acyclovir-Resistant Isolates of Herpes Simplex Virus Types 1 and 2. Antimicrobial Agents and Chemotherapy 56: 5735-5743

Svensson K, Sjodin A, Bystrom M, Granberg M, Brittnacher MJ, Rohmer L, Jacobs MA, Sims-Day EH, Levy R, Zhou Y, Hayden HS, Lim R, Chang J, Guenthener D, Kang A, Haugen E, Gillett W, Kaul R, Forsman M, Larsson P , Johansson A. (2012) Genome Sequence of Francisella tularensis subspecies holarctica Strain FSC200, Isolated from a Child with Tularemia. Journal of Bacteriology 194: 6965-6966

Thanikkal EJ, Mangu JCK, Francis MS (2012) Interactions of the CpxA sensor kinase and cognate CpxR response regulator from Yersinia pseudotuberculosis. BMC research notes 5: 536-536

Thein M, Bonde M, Bunikis I, Denker K, Sickmann A, Bergström S, Benz R (2012) DipA, a Pore-Forming Protein in the Outer Membrane of Lyme Disease Spirochetes Exhibits Specificity for the Permeation of Dicarboxylates. Plos One 7: 12

Twine S, Shen H, Harris G, Chen W, Sjöstedt A, Ryden P, Conlan W (2012) BALB/c mice, but not C57BL/6 mice immunized with a DeltaclpB mutant of Francisella tularensis subspecies tularensis are protected against respiratory challenge with wild-type bacteria: association of protection with post-vaccination and post-challenge immune responses. Vaccine 30: 3634-45

Twine SM, Vinogradov E, Lindgren H, Sjöstedt A, Conlan JW (2012) Roles for wbtC, wbtI, and kdtA Genes in Lipopolysaccharide Biosynthesis, Protein Glycosylation, Virulence, and Immunogenicity in Francisella tularensis2 Strain SCHU S4. Pathogens 1: 12-29

Ur-Rehman T, Nordfelth R, Blomgren A, Zetterström CE, Elofsson M, Gylfe A (2012) Preliminary Pharmacokinetics of the Bacterial Virulence Inhibitor N '-(3,5-Dibromo-2-HydroxyBenzylidenene)-Nicotinic Acid Hydrazide. In Advances in Yersinia Research, DeAlmeida AMP, Leal NC (eds) pp 349-356.

Ur-Rehman T, Slepenkin A, Chu H, Blomgren A, Dahlgren MK, Zetterström CE, Peterson EM, Elofsson M, Gylfe A (2012) Pre-clinical pharmacokinetics and anti-chlamydial activity of salicylidene acylhydrazide inhibitors of bacterial type III secretion. Journal of Antibiotics 65: 397-404

Urban CF, Reichenbach J, Bianchi M, Niemiec MJ (2012) Neutrophil extracellular traps in opportunistic mycoses. Mycoses 55: 24-24

Valeru SP, Wai SN, Saeed A, Sandstrom G, Abd H (2012) ToxR of Vibrio cholerae affects biofilm, rugosity and survival with Acanthamoeba castellanii. BMC research notes 5: 33-33

Wang J, Ehlers P, Silander I, Axner O (2012) Speed-dependent effects in dispersion mode of detection and in noise-immune cavity-enhanced optical heterodyne molecular spectrometry: experimental demonstration and validation of predicted line shape. Journal of the Optical Society of America B-Optical Physics 29: 2980-2989

Wang JY, Ehlers P, Silander I, Westberg J, Axner O (2012) Speed-dependent Voigt dispersion line-shape function: applicable to techniques measuring dispersion signals. Journal of the Optical Society of America B-Optical Physics 29: 2971-2979

Westberg J, Wang J, Axner O (2012) Fast and non-approximate methodology for calculation of wavelength-modulated Voigt lineshape functions suitable for real-time curve fitting. Journal of Quantitative Spectroscopy & Radiative Transfer 113: 2049-2057

Westermark L, Fahlgren A, Fällman M (2012) Immune response to diphtheria toxin-mediated depletion complicates the use of the CD11c-DTRtg model for studies of bacterial gastrointestinal infections. Microbial Pathogenesis 53: 154-161

Westermark L, Fahlgren A, Fällman M (2012) Immune response to diphtheria toxin-mediated depletion complicates the use of the CD11c-DTRtg model for studies of bacterial gastrointestinal infections. Immunology 137: 271-271

Widerstrom M, Wistrom J, Sjöstedt A, Monsen T (2012) Coagulase-negative staphylococci: update on the molecular epidemiology and clinical presentation, with a focus on Staphylococcus epidermidis and Staphylococcus saprophyticus. European Journal of Clinical Microbiology & Infectious Diseases 31: 7-20

Zakrisson J, Wiklund K, Axner O, Andersson M (2012) Helix-like biopolymers can act as dampers of force for bacteria in flows. European Biophysics Journal with Biophysics Letters 41: 551-560

Zhou Y, Smith D, Leong BJ, Brannstrom K, Almqvist F, Chapman MR (2012) Promiscuous Cross-seeding between Bacterial Amyloids Promotes Interspecies Biofilms. Journal of Biological Chemistry 287: 35092-35103

Akram N, Palovaara J, Forsberg J, Lindh MV, Milton DL, Luo H, Gonzalez JM, Pinhassi J (2013) Regulation of proteorhodopsin gene expression by nutrient limitation in the marine bacterium Vibrio sp AND4. Environmental Microbiology 15: 1400-1415

Publikationer 2011

Akopyan K, Edgren T, Wang-Edgren H, Rosqvist R, Fahlgren A, Wolf-Watz H, Fällman M (2011) Translocation of surface-localized effectors in type III secretion. Proc Natl Acad Sci U S A 108: 1639-1644

Amer AAA, Ahlund MK, Bröms JE, Forsberg Å, Francis MS (2011) Impact of the N-Terminal Secretor Domain on YopD Translocator Function in Yersinia pseudotuberculosis Type III Secretion. Journal of Bacteriology 193: 6683-6700

Andersson H, Olsson R, Almqvist F (2011) Reactions between Grignard reagents and heterocyclic N-oxides: Stereoselective synthesis of substituted pyridines, piperidines, and piperazines. Organic & Biomolecular Chemistry 9: 337-346

Andersson IE, Andersson CD, Batsalova T, Dzhambazov B, Holmdahl R, Kihlberg J, Linusson A (2011) Design of Glycopeptides Used to Investigate Class II MHC Binding and T-Cell Responses Associated with Autoimmune Arthritis. Plos One 6: 14

Andersson IE, Batsalova T, Haag S, Dzhambazov B, Holmdahl R, Kihberg J, Linusson A (2011) (E)-Alkene and Ethylene Isosteres Substantially Alter the Hydrogen-Bonding Network in Class II MHC A(q)/Glycopeptide Complexes and Affect T-Cell Recognition. Journal of the American Chemical Society 133: 14368-14378

Aoki K, Benko M, Davison AJ, Echavarria M, Erdman DD, Harrach B, Kajon AE, Schnurr D, Wadell G (2011) Toward an integrated human adenovirus designation system that utilizes molecular and serological data and serves both clinical and fundamental virology. J Virol 85: 5703-5704

Aplander K, Marttila M, Manner S, Arnberg N, Sterner O, Ellervik U (2011) Molecular Wipes: Application to Epidemic Keratoconjuctivitis. J Med Chem 54: 6670-6675

Axner O, Andersson M, Bjoernham O, Castelain M, Klinth J, Koutris E, Schedin S (2011) Assessing Bacterial Adhesion on an Individual Adhesin and Single Pili Level Using Optical Tweezers. Bacterial Adhesion: Chemistry, Biology and Physics 715: 301-313

Basmarke-Wehelie R, Sjolinder H, Jurkowski W, Elofsson A, Arnqvist A, Engstrand L, Hagner M, Wallin E, Guan N, Kuranasekera H, Aro H, Jonsson AB (2011) The Complement Regulator CD46 Is Bactericidal to Helicobacter pylori and Blocks Urease Activity. Gastroenterology 141: 918-928

Bengtsson C, Almqvist F (2011) A Selective Intramolecular 5-exo-dig or 6-endo-dig Cyclization en Route to 2-Furanone or 2-Pyrone Containing Tricyclic Scaffolds. Journal of Organic Chemistry 76: 9817-9825

Berg L, Andersson CD, Artursson E, Hornberg A, Tunemalm AK, Linusson A, Ekstrom F (2011) Targeting Acetylcholinesterase: Identification of Chemical Leads by High Throughput Screening, Structure Determination and Molecular Modeling. Plos One 6: 12

Bianchi M, Niemiec MJ, Siler U, Urban CF, Reichenbach J (2011) Redundant ability of phagocytes to kill Aspergillus species Reply. Journal of Allergy and Clinical Immunology 128: 687-688

Bianchi M, Niemiec MJ, Siler U, Urban CF, Reichenbach J (2011). Restoration of anti-Aspergillus defense by neutrophil extracellular traps in human chronic granulomatous disease after gene therapy is calprotectin-dependent. J Allergy Clin Immunol 127: 1243-1252 e7

Bielig H, Rompikuntal PK, Dongre M, Zurek B, Lindmark B, Ramstedt M, Wai SN, Kufer TA (2011) NOD-Like Receptor Activation by Outer Membrane Vesicles from Vibrio cholerae Non-O1 Non-O139 Strains Is Modulated by the Quorum-Sensing Regulator HapR. Infection and Immunity 79: 1418-1427

Björkström NK, Lindgren T, Stoltz M, Fauriat C, Braun M, Evander M, Michaelsson J, Malmberg KJ, Klingström J, Ahlm C, Ljunggren HG (2011) Rapid expansion and long-term persistence of elevated NK cell numbers in humans infected with hantavirus. J Exp Med 208: 13-21

Broman T, Thelaus J, Andersson AC, Backman S, Wikström P, Larsson E, Granberg M, Karlsson L, Back E, Eliasson H, Mattsson R, Sjöstedt A, Forsman M (2011) Molecular Detection of Persistent Francisella tularensis Subspecies holarctica in Natural Waters. Int J Microbiol 2011

Bröms JE, Lavander M, Meyer L, Sjöstedt A (2011) IglG and IglI of the Francisella pathogenicity island are important virulence determinants of Francisella tularensis LVS. Infect Immun 79: 3683-3696

Bunikis I, Kutschan-Bunikis S, Bonde M, Bergström S (2011) Multiplex PCR as a tool for validating plasmid content of Borrelia burgdorferi. J Microbiol Methods 86: 243-247

Castelain M, Ehlers S, Klinth J, Lindberg S, Andersson M, Uhlin BE, Axner O (2011) Fast uncoiling kinetics of F1C pili expressed by uropathogenic Escherichia coli are revealed on a single pilus level using force-measuring optical tweezers. Eur Biophys J 40: 305-316

Comstedt P, Jakobsson T, Bergström S (2011) Global ecology and epidemiology of Borrelia garinii spirochetes. Infection ecology & epidemiology 1

Dahlström LA, Andersson K, Luostarinen T, Thoresen S, Ogmundsdottir H, Tryggvadottir L, Wiklund F, Skare GB, Eklund C, Sjolin K, Jellum E, Koskela P, Wadell G, Lehtinen M, Dillner J (2011) Prospective Seroepidemiologic Study of Human Papillomavirus and Other Risk Factors in Cervical Cancer. Cancer Epidemiology Biomarkers & Prevention 20: 2541-2550

Deem A, Keszthelyi A, Blackgrove T, Vayl A, Coffey B, Mathur R, Chabes A, Malkova A (2011) Break-Induced Replication Is Highly Inaccurate. Plos Biology 9: 14

Deltcheva E, Chylinski K, Sharma CM, Gonzales K, Chao Y, Pirzada ZA, Eckert MR, Vogel J, Charpentier E (2011) CRISPR RNA maturation by trans-encoded small RNA and host factor RNase III. Nature 471: 602-607

Doherty GJ, Ahlund MK, Howes MT, Moren B, Parton RG, McMahon HT, Lundmark R (2011) The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading. Mol Biol Cell 22: 4380-4389

Dongre M, Uhlin BE, Wai SN (2011) Bacterial nanotubes for intimate sharing. Front Microbiol 2: 108

Egge-Jacobsen W, Salomonsson EN, Aas FE, Forslund AL, Winther-Larsen HC, Maier J, Macellaro A, Kuoppa K, Oyston PCF, Titball RW, Thomas RM, Forsberg Å, Prior JL, Koomey M (2011) O-Linked Glycosylation of the PilA Pilin Protein of Francisella tularensis: Identification of the Endogenous Protein-Targeting Oligosaccharyltransferase and Characterization of the Native Oligosaccharide. Journal of Bacteriology 193: 5487-5497

Eneslatt K, Rietz C, Ryden P, Stoven S, House RV, Wolfraim LA, Tarnvik A, Sjöstedt A (2011) Persistence of cell-mediated immunity three decades after vaccination with the live vaccine strain of Francisella tularensis. European Journal of Immunology 41: 974-980

Eriksson C, Kokkonen H, Johansson M, Hallmans G, Wadell G, Rantapaa-Dahlqvist S (2011) Autoantibodies predate the onset of systemic lupus erythematosus in northern Sweden. Arthritis Research & Therapy 13:R30: R30

Farto R, Milton DL, Bermudez MB, Nieto TP (2011) Colonization of turbot tissues by virulent and avirulent Aeromonas salmonicida subsp salmonicida strains during infection. Diseases of Aquatic Organisms 95: 167-173

Fei YY, Schmidt A, Bylund G, Johansson DX, Henriksson S, Lebrilla C, Solnick JV, Borén T, Zhu XD (2011) Use of Real-Time, Label-Free Analysis in Revealing Low-Affinity Binding to Blood Group Antigens by Helicobacter pylori. Analytical Chemistry 83: 6336-6341

Foltynowicz A, Silander I, Axner O (2011) Reduction of background signals in fiber-based NICE-OHMS. Journal of the Optical Society of America B-Optical Physics 28: 2797-2805

Fulton KM, Zhao X, Petit MD, Kilmury SLN, Wolfraim LA, House RV, Sjöstedt A, Twine SM (2011) Immunoproteomic analysis of the human antibody response to natural tularemia infection with Type A or Type B strains or LVS vaccination. International Journal of Medical Microbiology 301: 591-601

Hainzl T, Huang SH, Merilainen G, Brännström K, Sauer-Eriksson AE (2011) Structural basis of signal-sequence recognition by the signal recognition particle. Nature Structural & Molecular Biology 18: 389-391

Hassan OA, Ahlm C, Evander M (2011) Rift Valley Fever. A Need for a One Health Approach to Curb. Case Study from Sudan. EcoHealth 7: S138-S138

Hassan OA, Ahlm C, Sang R, Evander M (2011) The 2007 Rift Valley Fever Outbreak in Sudan. Plos Neglect Trop Dis 5: 7

Huang SH, Hainzl T, Grundström C, Forsman C, Samuelsson G, Sauer-Eriksson AE (2011) Structural Studies of beta-Carbonic Anhydrase from the Green Alga Coccomyxa: Inhibitor Complexes with Anions and Acetazolamide. Plos One 6: e28458

Ishijima N, Suzuki M, Ashida H, Ichikawa Y, Kanegae Y, Saito I, Borén T, Haas R, Sasakawa C, Mimuro H (2011) BabA-mediated Adherence Is a Potentiator of the Helicobacter pylori Type IV Secretion System Activity. Journal of Biological Chemistry 286: 25256-25264

Ito Y, Vela JL, Matsumura F, Hoshino H, Lee H, Kobayashi M, Bao X, Borén T, Jin R, Seeberger PH, Nakayama J, Kronenberg M, Fukuda M (2011) Immunological Functions of Cholesteryl alpha-glucosides in Helicobacter pylori-associated Inflammation. Glycobiology 21: 1485-1486

Johansson E, Speck C, Chabes A (2011) A top-down view on DNA replication and recombination from 9,000 feet above sea level. Genome Biol 12: 304

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Kluczynski P, Lundqvist S, Westberg J, Axner O (2011) Faraday rotation spectrometer with sub-second response time for detection of nitric oxide using a cw DFB quantum cascade laser at 5.33 mu m. Applied Physics B-Lasers and Optics 103: 451-459

Kokkonen H, Mullazehi M, Berglin E, Hallmans G, Wadell G, Ronnelid J, Rantapaa-Dahlqvist S (2011) Antibodies of IgG, IgA and IgM isotypes against cyclic citrullinated peptide precede the development of rheumatoid arthritis. Arthritis Research & Therapy 13:R13: R13

Kumar D, Abdulovic AL, Viberg J, Nilsson AK, Kunkel TA, Chabes A (2011) Mechanisms of mutagenesis in vivo due to imbalanced dNTP pools. Nucleic Acids Research 39: 1360-1371

Kumru OS, Bunikis I, Sorokina I, Bergström S, Zuckert WR (2011) Specificity and Role of the Borrelia burgdorferi CtpA Protease in Outer Membrane Protein Processing. Journal of Bacteriology 193: 5759-5765

Lathdavong L, Shao J, Kluczynski P, Lundqvist S, Axner O (2011) Methodology for detection of carbon monoxide in hot, humid media by telecommunication distributed feedback laser-based tunable diode laser absorption spectrometry. Applied Optics 50: 2531-2550

Lenman A, Muller S, Nygren MI, Frangsmyr L, Stehle T, Arnberg N (2011) Coagulation Factor IX Mediates Serotype-Specific Binding of Species A Adenoviruses to Host Cells. Journal of Virology 85: 13420-13431

Lindgren H, Honn M, Salomonsson E, Kuoppa K, Forsberg Å, Sjöstedt A (2011) Iron Content Differs between Francisella tularensis Subspecies tularensis and Subspecies holarctica Strains and Correlates to Their Susceptibility to H2O2-Induced Killing. Infection and Immunity 79: 1218-1224

Lindgren T, Ahlm C, Mohamed N, Evander M, Ljunggren HG, Björkström NK (2011) Longitudinal Analysis of the Human T Cell Response during Acute Hantavirus Infection. Journal of Virology 85: 10252-10260

Lindström A, Edvinsson L, Johansson A, Andersson CD, Andersson IE, Raubacher F, Linusson A (2011) Postprocessing of Docked Protein-Ligand Complexes Using Implicit Solvation Models. Journal of Chemical Information and Modeling 51: 267-282

Liu JF, Obi IR, Thanikkal EJ, Kieselbach T, Francis MS (2011) Phosphorylated CpxR Restricts Production of the RovA Global Regulator in Yersinia pseudotuberculosis. Plos One 6: e23314

Luostarinen T, Dahlström LA, Andersson K, Ogmundsdottir H, Jellum E, Koskela P, Wadell G, Lehtinen M, Dillner J (2011) Human Papillomavirus, other sexually transmitted infections and risk of cervical cancer. A Nordic joint study. Journal of Epidemiology and Community Health 65: A266-A266

Lyszkiewicz M, Zietara N, Rohde M, Gekara NO, Jablonska J, Dittmar KE, Weiss S (2011) SIGN-R1(+)MHC II+ cells of the splenic marginal zone-a novel type of resident dendritic cells. Journal of Leukocyte Biology 89: 607-615

Makarova KS, Haft DH, Barrangou R, Brouns SJ, Charpentier E, Horvath P, Moineau S, Mojica FJ, Wolf YI, Yakunin AF, van der Oost J, Koonin EV (2011) Evolution and classification of the CRISPR-Cas systems. Nat Rev Microbiol 9: 467-477

Mansjo M, Johansson J (2011) The Riboflavin analog roseoflavin targets an FMN-riboswitch and blocks Listeria monocytogenes growth, but also stimulates virulence gene-expression and infection. RNA Biology 8: 674-680

Marcinowska R, Trygg J, Wolf-Watz H, Mortiz T, Surowiec I (2011) Optimization of a sample preparation method for the metabolomic analysis of clinically relevant bacteria. J Microbiol Methods 87: 24-31

Meinzer U, Barreau F, Jung C, Esmiol-Welterlin S, Berrebi D, Dussaillant M, Bonacorsi S, Wolf-Watz H, Perroy J, Ollendorff V, Hugot JP (2011) Yersinia Pseudotuberculosis Effector Yopj Subverts TAK1 and NOD2 Functions to Elicit Intestinal Barrier Dysfunction. Gastroenterology 140: S634-S634

Mistry N, Inoue H, Jamshidi F, Storm RJ, Oberste MS, Arnberg N (2011) Coxsackievirus A24 Variant Uses Sialic Acid-Containing O-Linked Glycoconjugates as Cellular Receptors on Human Ocular Cells. Journal of Virology 85: 11283-11290

Moore ME, Borén T, Solnick JV (2011) Life at the margins: modulation of attachment proteins in Helicobacter pylori. Gut microbes 2: 42-6

Näslund J, Kerner A, Drobni P, Bucht G, Evander M, Ahlm C (2011) Detection of Puumala and Rift Valley Fever virus by quantitative RT-PCR and virus viability tests in samples of blood dried and stored on filter paper. J Virol Methods 178: 186-190

Nilsson EC, Storm RJ, Bauer J, Johansson SMC, Lookene A, Ångström J, Hedenström M, Eriksson TL, Fängsmyr L, Rinaldi S, Willison HJ, Domellöf FP, Stehle T, Arnberg N (2011) The GD1a glycan is a cellular receptor for adenoviruses causing epidemic keratoconjunctivitis. Nature Medicine 17: 105-U279

Nylander A, Forsgren N, Persson K (2011) Structure of the C-terminal domain of the surface antigen SpaP from the caries pathogen Streptococcus mutans. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 67: 23-26

Obi IR, Nordfelth R, Francis MS (2011) Varying dependency of periplasmic peptidylprolyl cis-trans isomerases in promoting Yersinia pseudotuberculosis stress tolerance and pathogenicity. Biochemical Journal 439: 321-332

Ohno T, Vallström A, Rugge M, Ota H, Graham DY, Arnqvist A, Yamaoka Y (2011) Effects of Blood Group Antigen-Binding Adhesin Expression during Helicobacter pylori Infection of Mongolian Gerbils. Journal of Infectious Diseases 203: 726-735

Olofsson K, Loizou C, Evander M, Mincheva-Nilsson L, Laurell G (2011) [A study of laryngeal papilloma in northern Sweden. Two cases of oncogenic HPV among 26 patients]. Lakartidningen 108: 1187-1189

Överby AK, Weber F (2011) Hiding from intracellular pattern recognition receptors, a passive strategy of flavivirus immune evasion. Virulence 2: 238-240

Persson K (2011) Crystallization of the fimbrial protein FimP from Actinomyces oris and of a triple Ile-to-Met mutant engineered to facilitate selenomethionine labelling. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 67: 1207-1210

Persson K (2011) Structure of the sortase AcSrtC-1 from Actinomyces oris. Acta Crystallographica Section D-Biological Crystallography 67: 212-217

Pettersson L, Rasmuson J, Andersson C, Ahlm C, Evander M (2011) Hantavirus-Specific IgA in Saliva and Viral Antigen in the Parotid Gland in Patients With Hemorrhagic Fever With Renal Syndrome. J Med Virol 83: 864-870

Ramstedt M, Nakao R, Wai SN, Uhlin BE, Boily JF (2011) Monitoring surface chemical changes in the bacterial cell wall: multivariate analysis of cryo-x-ray photoelectron spectroscopy data. J Biol Chem 286: 12389-12396

Rasmuson J, Andersson C, Norrman E, Haney M, Evander M, Ahlm C (2011) Time to revise the paradigm of hantavirus syndromes? Hantavirus pulmonary syndrome caused by European hantavirus. European Journal of Clinical Microbiology & Infectious Diseases 30: 685-690

Rossmann MP, Luo WJ, Tsaponina O, Chabes A, Stillman B (2011) A Common Telomeric Gene Silencing Assay Is Affected by Nucleotide Metabolism. Molecular Cell 42: 127-136

Rzhepishevska O, Ekstrand-Hammarstrom B, Popp M, Bjorn E, Bucht A, Sjöstedt A, Antti H, Ramstedt M (2011) The Antibacterial Activity of Ga3+ Is Influenced by Ligand Complexation as Well as the Bacterial Carbon Source. Antimicrobial Agents and Chemotherapy 55: 5568-5580

Sachl R, Rosenbaum E, Sellstedt M, Almqvist F, Johansson LBA (2011) Locations and Reorientations of Multi-Ring-Fused 2-Pyridones in Ganglioside G(M1) Micelles. Langmuir 27: 1662-1667

Salomonsson EN, Forslund AL, Forsberg Å (2011) Type IV Pili in Francisella - A virulence trait in an intracellular pathogen. Front Microbiol 2: 29

Sellstedt M, Almqvist F (2011) A Three-Component Reaction Forming Naphthyridones - Synthesis of Lophocladine Analogs. Organic Letters 13: 5278-5281

Sjöstedt A (2011) Special topic on Francisella tularensis and tularemia. Frontiers in Microbiology 2: 86

Sjöström S, Hjalmars U, Juto P, Wadell G, Hallmans G, Tjonneland A, Halkjaer J, Manjer J, Almquist M, Melin BS (2011) Human immunoglobulin G levels of viruses and associated glioma risk. Cancer Causes & Control 22: 1259-1266

Sjowall J, Fryland L, Nordberg M, Sjogren F, Garpmo U, Jansson C, Carlsson SA, Bergström S, Ernerudh J, Nyman D, Forsberg P, Ekerfelt C (2011) Decreased Th1-Type Inflammatory Cytokine Expression in the Skin Is Associated with Persisting Symptoms after Treatment of Erythema Migrans. Plos One 6

Slepenkin A, Chu H, Elofsson M, Keyser P, Peterson EM (2011) Protection of Mice From a Chlamydia trachomatis Vaginal Infection Using a Salicylidene Acylhydrazide, a Potential Microbicide. Journal of Infectious Diseases 204: 1313-1320

Spjut S, Qian WX, Bauer J, Storm R, Frangsmyr L, Stehle T, Arnberg N, Elofsson M (2011) A Potent Trivalent Sialic Acid Inhibitor of Adenovirus Type 37 Infection of Human Corneal Cells. Angew Chem-Int Edit 50: 6519-6521

Stone JE, Kumar D, Binz SK, Inase A, Iwai S, Chabes A, Burgers PM, Kunkel TA (2011) Lesion bypass by S-cerevisiae Pol zeta alone. DNA Repair 10: 826-834

Tancred L, Telepnev MV, Golovliov I, Andersson B, Andersson H, Lindgren H, Sjöstedt A (2011) Administration of a nitric oxide donor inhibits mglA expression by intracellular Francisella tularensis and counteracts phagosomal escape and subversion of TNF-alpha secretion. Journal of Medical Microbiology 60: 1570-1583

Thorslund SE, Edgren T, Pettersson J, Nordfelth R, Sellin ME, Ivanova E, Francis MS, Isaksson EL, Wolf-Watz H, Fällman M (2011) The RACK1 Signaling Scaffold Protein Selectively Interacts with Yersinia pseudotuberculosis Virulence Function. Plos One 6: e16784

Tsaponina O, Barsoum E, Astrom SU, Chabes A (2011) Ixr1 Is Required for the Expression of the Ribonucleotide Reductase Rnr1 and Maintenance of dNTP Pools. PLoS genetics 7: e1002061

Verbruggen P, Ruf M, Blakqori G, Överby AK, Heidemann M, Eick D, Weber F (2011) Interferon Antagonist NSs of La Crosse Virus Triggers a DNA Damage Response-like Degradation of Transcribing RNA Polymerase II. Journal of Biological Chemistry 286: 3681-3692

Vethanayagam RR, Almyroudis NG, Grimm MJ, Lewandowski DC, Pham CT, Blackwell TS, Petraitiene R, Petraitis V, Walsh TJ, Urban CF, Segal BH (2011) Role of NADPH oxidase versus neutrophil proteases in antimicrobial host defense. PLoS One 6: e28149

Wang D, Zetterstrom CE, Gabrielsen M, Beckham KSH, Tree JJ, Macdonald SE, Byron O, Mitchell TJ, Gally DL, Herzyk P, Mahajan A, Uvell H, Burchmore R, Smith BO, Elofsson M, Roe AJ (2011) Identification of Bacterial Target Proteins for the Salicylidene Acylhydrazide Class of Virulence-blocking Compounds. Journal of Biological Chemistry 286: 29922-29931

Wang J, Ehlers P, Silander I, Axner O (2011) Dicke narrowing in the dispersion mode of detection and in noise-immune cavity-enhanced optical heterodyne molecular spectroscopy-theory and experimental verification. Journal of the Optical Society of America B-Optical Physics 28: 2390-2401

Weber B, Lindell K, El Qaidi S, Hjerde E, Willassen N-P, Milton DL (2011) The phosphotransferase VanU represses expression of four qrr genes antagonizing VanO-mediated quorum-sensing regulation in Vibrio anguillarum. Microbiol-Sgm 157: 3324-3339

Westberg J, Kluczynski P, Lundqvist S, Axner O (2011) Analytical expression for the nth Fourier coefficient of a modulated Lorentzian dispersion lineshape function. Journal of Quantitative Spectroscopy & Radiative Transfer 112: 1443-1449

Yin S, Davis RA, Shelper T, Sykes ML, Avery VM, Elofsson M, Sundin C, Quinn RJ (2011) Pseudoceramines A-D, new antibacterial bromotyrosine alkaloids from the marine sponge Pseudoceratina sp. Organic & Biomolecular Chemistry 9: 6755-6760

Publikationer 2010

Andersson CD, Chen BY, Linusson A (2010) Mapping of ligand-binding cavities in proteins. Proteins 78: 1408-1422

Andersson CD, Chen BY, Linusson A (2010) Multivariate assessment of virtual screening experiments. J Chemometr 24: 757-767

Andersson EK, Mei YF, Wadell G (2010) Adenovirus interactions with CD46 on transgenic mouse erythrocytes. Virology 402: 20-25

Andersson EK, Strand M, Edlund K, Lindman K, Enquist PA, Spjut S, Allard A, Elofsson M, Mei YF, Wadell G (2010) Small-Molecule Screening Using a Whole-Cell Viral Replication Reporter Gene Assay Identifies 2-{ 2-(Benzoylamino)Benzoyl Amino}-Benzoic Acid as a Novel Antiadenoviral Compound. Antimicrobial Agents and Chemotherapy 54: 3871-3877

Andersson H, Banchelin TS, Das S, Olsson R, Almqvist F (2010) Efficient, mild and completely regioselective synthesis of substituted pyridines. Chemical Communications 46: 3384-3386

Andersson H, Banchelin TSL, Das S, Gustafsson M, Olsson R, Almqvist F (2010) Complete Regioselective Addition of Grignard Reagents to Pyrazine N-Oxides, Toward an Efficient Enantioselective Synthesis of Substituted Piperazines. Organic Letters 12: 284-286

Andersson H, Das S, Gustafsson M, Olsson R, Almqvist F (2010) Synthesis of substituted 4-pyridones and 4-aminopyridinium salts via a one-pot pyridine synthesis. Tetrahedron Letters 51: 4218-4220

Andersson IE, Batsalova T, Dzhambazov B, Edvinsson L, Holmdahl R, Kihlberg J, Linusson A (2010) Oxazole-modified glycopeptides that target arthritis-associated class II MHC A(q) and DR4 proteins. Organic & Biomolecular Chemistry 8: 2931-2940

Axner O, Bjornham O, Castelain M, Koutris E, Schedin S, Fallman E, Andersson M (2010) Unraveling the Secrets of Bacterial Adhesion Organelles Using Single-Molecule Force Spectroscopy. In Single Molecule Spectroscopy in Chemistry, Physics and Biology, Graslund A, Rigler R, Widengren J (eds) pp 337-362.

Barcena-Uribarri I, Thein M, Sacher A, Bunikis I, Bonde M, Bergström S, Benz R (2010) P66 porins are present in both Lyme disease and relapsing fever spirochetes: a comparison of the biophysical properties of P66 porins from six Borrelia species. Biochim Biophys Acta 1798: 1197-1203

Bengtsson C, Almqvist F (2010) Regioselective Halogenations and Subsequent Suzuki-Miyaura Coupling onto Bicyclic 2-Pyridones. Journal of Organic Chemistry 75: 972-975

Bergström S, Zückert WR (2010) Structure, function and biogenesis of the Borrelia cell envelope. In Borrelia, Molecular Biology, Host Interactions and Pathogenesis Eds DS Samuels and JD Radolf, pp 139-166. Norfolk, UK: Caister Academic Press

Bjornham O, Axner O (2010) Catch-Bond Behavior of Bacteria Binding by Slip Bonds. Biophysical Journal 99: 1331-1341

Brady LJ, Maddocks SE, Larson MR, Forsgren N, Persson K, Deivanayagam CC, Jenkinson HF (2010) The changing faces of Streptococcus antigen I/II polypeptide family adhesins. Molecular Microbiology 77: 276-286

Bröms JE, Sjöstedt A, Lavander M (2010) The role of the Francisella tularensis pathogenicity island in type VI secretion, intracellular survival, and modulation of host cell signaling. Front Microbiol 1: 136

Chen T, Lundin E, Grankvist K, Zeleniuch-Jacquotte A, Wulff M, Afanasyeva Y, Schock H, Johansson R, Lenner P, Hallmans G, Wadell G, Toniolo P, Lukanova A (2010) Maternal hormones during early pregnancy: a cross-sectional study. Cancer Causes & Control 21: 719-727

Chen TH, Lukanova A, Grankvist K, Zeleniuch-Jacquotte A, Wulff M, Johansson R, Schock H, Lenner P, Hallmans G, Wadell G, Toniolo P, Lundin E (2010) IGF-I during primiparous pregnancy and maternal risk of breast cancer. Breast Cancer Research and Treatment 121: 169-175

Chorell E, Edvinsson S, Almqvist F (2010) Improved procedure for the enantioselective synthesis of dihydrooxazolo and dihydrothiazolo ring-fused 2-pyridones. Tetrahedron Letters 51: 2461-2463

Chorell E, Pinkner JS, Phan G, Edvinsson S, Buelens F, Remaut H, Waksman G, Hultgren SJ, Almqvist F (2010) Design and Synthesis of C-2 Substituted Thiazolo and Dihydrothiazolo Ring-Fused 2-Pyridones: Pilicides with Increased Antivirulence Activity. J Med Chem 53: 5690-5695

Chu H, Slepenkin A, Elofsson M, Keyser P, de la Maza LM, Peterson EM (2010) Candidate vaginal microbicides with activity against Chlamydia trachomatis and Neisseria gonorrhoeae. International journal of antimicrobial agents 36: 145-150

Conlan JW, Shen H, Golovliov I, Zingmark C, Oyston PC, Chen W, House RV, Sjöstedt A (2010) Differential ability of novel attenuated targeted deletion mutants of Francisella tularensis subspecies tularensis strain SCHU S4 to protect mice against aerosol challenge with virulent bacteria: effects of host background and route of immunization. Vaccine 28: 1824-1831

Costa TR, Edqvist PJ, Bröms JE, Ahlund MK, Forsberg Å, Francis MS (2010) YopD self-assembly and binding to LcrV facilitate type III secretion activity by Yersinia pseudotuberculosis. J Biol Chem 285: 25269-25284

Cupelli K, Muller S, Persson BD, Jost M, Arnberg N, Stehle T (2010) Structure of Adenovirus Type 21 Knob in Complex with CD46 Reveals Key Differences in Receptor Contacts among Species B Adenoviruses. Journal of Virology 84: 3189-3200

Dahlgren MK, Öberg CT, Wallin EA, Janson PG, Elofsson M (2010) Synthesis of 2-(2-Aminopyrimidine)-2,2-difluoroethanols as Potential Bioisosters of Salicylidene Acylhydrazides. Molecules 15: 4423-4438

Dahlgren MK, Zetterstrom CE, Gylfe A, Linusson A, Elofsson M (2010) Statistical molecular design of a focused salicylidene acylhydrazide library and multivariate QSAR of inhibition of type III secretion in the Gram-negative bacterium Yersinia. Bioorganic & Medicinal Chemistry 18: 2686-2703

Debruyne L, Broman T, Bergström S, Olsen B, On SLW, Vandamme P (2010) Campylobacter volucris sp nov., isolated from black-headed gulls (Larus ridibundus). International Journal of Systematic and Evolutionary Microbiology 60: 1870-1875

Elfving K, Olsen B, Bergström S, Waldenström J, Lundkvist A, Sjöstedt A, Mejlon H, Nilsson K (2010) Dissemination of spotted fever rickettsia agents in Europe by migrating birds. PLoS One 5: e8572

Engström P, Bailey L, Onskog T, Bergström S, Johansson J (2010) A comparative study of RNA and DNA as internal gene expression controls early in the developmental cycle of Chlamydia pneumoniae. FEMS Immunol Med Microbiol 58: 244-253

Fasullo M, Tsaponina O, Sun MZ, Chabes A (2010) Elevated dNTP levels suppress hyper-recombination in Saccharomyces cerevisiae S-phase checkpoint mutants. Nucleic Acids Research 38: 1195-1203

Foltynowicz A, Wang JY, Ehlers P, Axner O (2010) Distributed-feedback-laser-based NICE-OHMS in the pressure-broadened regime. Optics Express 18: 18580-18591

Forsgren N, Lamont RJ, Persson K (2010) Two Intramolecular Isopeptide Bonds are Identified in the Crystal Structure of the Streptococcus gordonii SspB C-terminal Domain. Journal of Molecular Biology 397: 740-751

Forslund AL, Salomonsson EN, Golovliov I, Kuoppa K, Michell S, Titball R, Oyston P, Noppa L, Sjöstedt A, Forsberg Å (2010) The type IV pilin, PilA, is required for full virulence of Francisella tularensis subspecies tularensis. BMC Microbiol 10: 227

Gabrielsen M, Zetterstrom CE, Wang D, Beckham KSH, Elofsson M, Isaacs NW, Roe AJ (2010) Expression, purification, crystallization and initial X-ray diffraction analysis of thiol peroxidase from Yersinia pseudotuberculosis. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 66: 1606-1609

Gautrot J, Huck W, Welch M, Ramstedt M (2010) Protein-Resistant NTA-Functionalized Polymer Brushes for Selective and Stable Immobilization of Histidine-Tagged Proteins. Acs Applied Materials & Interfaces 2: 193-202

Gekara NO, Zietara N, Geffers R, Weiss S (2010) Listeria monocytogenes Induces T Cell Receptor Unresponsiveness through Pore-Forming Toxin Listeriolysin O. Journal of Infectious Diseases 202: 1698-1707

Gomez-Consarnau L, Akram N, Lindell K, Pedersen A, Neutze R, Milton DL, Gonzalez JM, Pinhassi J (2010) Proteorhodopsin Phototrophy Promotes Survival of Marine Bacteria during Starvation. Plos Biology 8: 10

Gripenland J, Netterling S, Loh E, Tiensuu T, Toledo-Arana A, Johansson J (2010) RNAs: regulators of bacterial virulence. Nat Rev Microbiol 8: 857-866

Hillgren JM, Dahlgren MK, To TM, Elofsson M (2010) Synthesis of 4-(2-Hydroxyphenyl)thiazol-2-yl methanones as Potential Bioisosteres of Salicylidene Acylhydrazides. Molecules 15: 6019-6034

Howes MT, Kirkham M, Riches J, Cortese K, Walser PJ, Simpson F, Hill MM, Jones A, Lundmark R, Lindsay MR, Hernandez-Deviez DJ, Hadzic G, McCluskey A, Bashir R, Liu L, Pilch P, McMahon H, Robinson PJ, Hancock JF, Mayor S et al. (2010) Clathrin-independent carriers form a high capacity endocytic sorting system at the leading edge of migrating cells. J Cell Biol 190: 675-91

Hultdin UW, Lindberg S, Grundström C, Allgardsson A, Huang SH, Stier G, Öhman A, Uhlin BE, Sauer-Eriksson AE (2010) Purification, crystallization and preliminary data analysis of FocB, a transcription factor regulating fimbrial adhesin expression in uropathogenic Escherichia coli. Acta Crystallographica Section F-Structural Biology and Crystallization Communications 66: 337-341

Hultdin UW, Lindberg S, Grundstrom C, Huang SH, Uhlin BE, Sauer-Eriksson AE (2010) Structure of FocB - a member of a family of transcription factors regulating fimbrial adhesin expression in uropathogenic Escherichia coli. Febs Journal 277: 3368-3381

Keszthelyi A, Chabes A (2010) Altered ribonucleotide reductase (RNR) activity in yeast superoxide dismutase 1 (SOD1) deletion mutant. Febs Journal 277: 183-183

Kumar D, Abdulovic AL, Viberg J, Nilsson AK, Kunkel TA, Chabes A (2010) dNTP pool imbalances: Mechanism of mutagenesis and effects on cell cycle. Febs Journal 277: 187-187

Kumar D, Viberg J, Nilsson AK, Chabes A (2010) Highly mutagenic and severely imbalanced dNTP pools can escape detection by the S-phase checkpoint. Nucleic Acids Research 38: 3975-3983

Lathdavong L, Westberg J, Shao J, Dion CM, Kluczynski P, Lundqvist S, Axner O (2010) Faraday modulation spectrometry of nitric oxide addressing its electronic X-2 Pi - A(2)Sigma(+) band: I. theory. Applied Optics 49: 5597-5613

Lundmark R, Carlsson SR (2010) Driving membrane curvature in clathrin-dependent and clathrin-independent endocytosis. Semin Cell Dev Biol 21: 363-370

Lundqvist J, Larsson C, Nelson M, Andersson M, Bergström S, Persson C (2010) Concomitant infection decreases the malaria burden but escalates relapsing fever borreliosis. Infect Immun 78: 1924-1930

Magalhaes A, Gomes J, Ismail MN, Haslam SM, Mendes N, Osorio H, David L, Lependu J, Haas R, Dell A, Borén T, Reis CA (2010) Fut2-Null Mice Display An Altered Gastric Mucosa Glycosylation Profile and Modified Helicobacter pylori Adhesion. Glycobiology 20: 1460-1461

Martin S, Terry H, Bridgeman A, Harris C, Blair E, Arnberg N, Hanke T, Easton A, Burgert HG (2010) Potential of a New Subgroup D Adenovirus Vector for Vaccination. Human Gene Therapy 21: 497-498

McElhinny SAN, Kumar D, Clark AB, Watt DL, Watts BE, Lundström EB, Johansson E, Chabes A, Kunkel TA (2010) Genome instability due to ribonucleotide incorporation into DNA. Nat Chem Biol 6: 774-781

McElhinny SAN, Watts BE, Kumar D, Watt DL, Lundström EB, Burgers PMJ, Johansson E, Chabes A, Kunkel TA (2010) Abundant ribonucleotide incorporation into DNA by yeast replicative polymerases. Proceedings of the National Academy of Sciences of the United States of America 107: 4949-4954

Müller CM, Schneider G, Dobrindt U, Emody L, Hacker J, Uhlin BE (2010) Differential effects and interactions of endogenous and horizontally acquired H-NS-like proteins in pathogenic Escherichia coli. Molecular Microbiology 75: 280-293

Olofsson A, Vallstrom A, Petzold K, Tegtmeyer N, Schleucher J, Carlsson S, Haas R, Backert S, Wai SN, Gröbner G, Arnqvist A (2010) Biochemical and functional characterization of Helicobacter pylori vesicles. Molecular Microbiology 77: 1539-1555

Park HS, Östberg Y, Johansson J, Wagner EGH, Uhlin BE (2010) Novel role for a bacterial nucleoid protein in translation of mRNAs with suboptimal ribosome-binding sites. Genes & Development 24: 1345-1350

Ramstedt M, Franklyn P (2010) Difficulties in determining valence for Ag-0 nanoparticles using XPS - characterization of nanoparticles inside poly (3-sulphopropyl methacrylate) brushes. Surf Interface Anal 42: 855-858

Romby P, Charpentier E (2010) An overview of RNAs with regulatory functions in Gram-positive bacteria. Cell Mol Life Sci 67: 217-237

Rosenbaum E, Sellstedt M, Almqvist F, Johansson LBA (2010) Unusual Light Spectroscopic Properties of a 2-Pyridone-Based Multi-Ring-Fused Fluorescent Scaffold. J Fluoresc 20: 1249-1253

Schmidt FM, Ma W, Foltynowicz A, Axner O (2010) Highly sensitive dispersion spectroscopy by probing the free spectral range of an optical cavity using dual-frequency modulation. Applied Physics B-Lasers and Optics 101: 497-509

Sellstedt M, Nyberg A, Rosenbaum E, Engström P, Wickström M, Gullbo J, Bergström S, Johansson LBA, Almqvist F (2010) Synthesis and Characterization of a Multi Ring-Fused 2-Pyridone-Based Fluorescent Scaffold. European Journal of Organic Chemistry: 6171-6178

Shao J, Lathdavong L, Westberg J, Kluczynski P, Lundqvist S, Axner O (2010) Faraday modulation spectrometry of nitric oxide addressing its electronic X-2 Pi - A(2)Sigma(+) band: II. experiment. Applied Optics 49: 5614-5625

Shen H, Harris G, Chen W, Sjöstedt A, Ryden P, Conlan W (2010) Molecular immune responses to aerosol challenge with Francisella tularensis in mice inoculated with live vaccine candidates of varying efficacy. PLoS One 5: e13349

Song TY, Sabharwal D, Wai SN (2010) VrrA Mediates Hfq-Dependent Regulation of OmpT Synthesis in Vibrio cholerae. Journal of Molecular Biology 400: 682-688

Spjut S, Qian WX, Elofsson M (2010) Synthesis and Application of a 2- (4-Fluorophenyl)-sulfonyl ethoxy Carbonyl (Fsec) Protected Glycosyl Donor in Carbohydrate Chemistry. Molecules 15: 5708-5720

Styer CM, Hansen LM, Cooke CL, Gundersen AM, Choi SS, Berg DE, Benghezal M, Marshall BJ, Peek RM, Borén T, Solnick JV (2010) Expression of the BabA Adhesin during Experimental Infection with Helicobacter pylori. Infection and Immunity 78: 1593-1600

Syngkon A, Elluri S, Koley H, Rompikuntal PK, Saha DR, Chakrabarti MK, Bhadra RK, Wai SN, Pal A (2010) Studies on a novel serine protease of a DeltahapADeltaprtV Vibrio cholerae O1 strain and its role in hemorrhagic response in the rabbit ileal loop model. PLoS One 5(9): e13122.

Toledo A, Anda P, Escudero R, Larsson C, Bergström S, Benach JL (2010) Phylogenetic Analysis of a Virulent Borrelia Species Isolated from Patients with Relapsing Fever. Journal of Clinical Microbiology 48: 2484-2489

Tsaponina O, Chabes A (2010) HMG-box protein lxr1 is required for DNA-damage-induced expression of ribonucleotide reductase Rnr1. Febs Journal 277: 167-168

Weber B, Chen C, Milton DL (2010) Colonization of fish skin is vital for Vibrio anguillarum to cause disease. Environ Microbiol Rep 2: 133-139

Westberg J, Lathdavong L, Dion CM, Shao J, Kluczynski P, Lundqvist S, Axner O (2010) Quantitative description of Faraday modulation spectrometry in terms of the integrated linestrength and 1st Fourier coefficients of the modulated lineshape function. Journal of Quantitative Spectroscopy & Radiative Transfer 111: 2415-2433

Wilhelmsson P, Fryland L, Börjesson S, Nordgren J, Bergström S, Ernerudh J, Forsberg P, Lindgren PE (2010) Prevalence and diversity of Borrelia species in ticks that have bitten humans in Sweden. J Clin Microbiol 48: 4169-4176

Wolf-Watz H (2010) Yersinia blocks innate immunity via the TypeIII secretion system; a possible drug target for novel therapy? Febs Journal 277: 34-35

Yasmin L, Veesenmeyer JL, Diaz MH, Francis MS, Ottmann C, Palmer RH, Hauser AR, Hallberg B (2010) Electrostatic interactions play a minor role in the binding of ExoS to 14-3-3 proteins. Biochemical Journal 427: 217-224

Publikationer 2009

Aldick T, Bielaszewska M, Uhlin BE, Humpf HU, Wai SN, Karch H (2009) Vesicular stabilization and activity augmentation of enterohaemorrhagic Escherichia coli haemolysin. Mol Microbiol 71: 1496-508

Andersson H, Gustafsson M, Boström D, Olsson R, Almqvist F (2009) The Regio- and Stereoselective Synthesis of trans-2,3-Dihydropyridine N-oxides and Piperidines. Angew Chem-Int Edit 48: 3288-3291

Arnberg N (2009) Adenovirus receptors: implications for tropism, treatment and targeting. Reviews in Medical Virology 19: 165-178

Basu B, Das S, Das P, Mandal B, Banerjee D, Almqvist F (2009) Palladium Supported on a Polyionic Resin as an Efficient, Ligand-Free, and Recyclable Catalyst for Heck, Suzuki-Miyaura, and Sonogashira Reactions. Synthesis-Stuttgart: 1137-1146

Bjornfot AC, Lavander M, Forsberg Å, Wolf-Watz H (2009) Autoproteolysis of YscU of Yersinia pseudotuberculosis Is Important for Regulation of Expression and Secretion of Yop Proteins. Journal of Bacteriology 191: 4259-4267

Bjornham O, Axner O (2009) Multipili attachment of bacteria with helixlike pili exposed to stress. Journal of Chemical Physics 130: 235102

Björnham O, Bugaytsova J, Borén T, Schedin S (2009) Dynamic force spectroscopy of the Helicobacter pylori BabA-Lewis b binding. Biophys Chem 143: 102-105

Bröms J, Lavander M, Sjöstedt A (2009) A conserved alpha-helix essential for a type VI secretion-like system of Francisella tularensis. J Bacteriol 191: 2431-2446

Castelain M, Koutris E, Andersson M, Wiklund K, Bjornham O, Schedin S, Axner O (2009) Characterization of the Biomechanical Properties of T4 Pili Expressed by Streptococcus pneumoniae-A Comparison between Helix-like and Open Coil-like Pili. Chemphyschem 10: 1533-1540

Castelain M, Sjöström A, Fällman E, Uhlin B, Andersson M (2009) Unfolding and refolding properties of S pili on extraintestinal pathogenic Escherichia coli. Eur Biophys J 39: 1105-1115

Cegelski L, Pinkner JS, Hammer ND, Cusumano CK, Hung CS, Chorell E, Aberg V, Walker JN, Seed PC, Almqvist F, Chapman MR, Hultgren SJ (2009) Small-molecule inhibitors target Escherichia coli amyloid biogenesis and biofilm formation. Nat Chem Biol 5: 913-919

Champion MD, Zeng Q, Nix EB, Nano FE, Keim P, Kodira CD, Borowsky M, Young S, Koehrsen M, Engels R, Pearson M, Howarth C, Larson L, White J, Alvarado L, Forsman M, Bearden SW, Sjöstedt A, Titball R, Michell SL et al. (2009) Comparative genomic characterization of Francisella tularensis strains belonging to low and high virulence subspecies. PLoS Pathog 5: e1000459

Comstedt P, Asokliene L, Eliasson I, Olsen B, Wallensten A, Bunikis J, Bergström S (2009) Complex population structure of Lyme borreliosis group spirochete Borrelia garinii in subarctic Eurasia. PLoS One 4: e5841

Eriksson HM, Persson K, Zhang SG, Wieslander A (2009) High-yield expression and purification of a monotopic membrane glycosyltransferase. Protein Expression and Purification 66: 143-148

Fagerberg D, Ångström J, Halim A, Hultberg A, Rakhimova L, Hammarström L, Borén T, Teneberg S (2009) Novel Leb-like Helicobacter pylori-binding glycosphingolipid created by the expression of human alpha-1,3/4-fucosyltransferase in FVB/N mouse stomach. Glycobiology 19: 182-191

Fahlgren A, Westermark L, Akopyan K, Fällman M (2009) Cell type-specific effects of Yersinia pseudotuberculosis virulence effectors. Cell Microbiol 11: 1750-1767

Foltynowicz A, Ma WG, Schmidt FM, Axner O (2009) Wavelength-modulated noise-immune cavity-enhanced optical heterodyne molecular spectroscopy signal line shapes in the Doppler limit. Journal of the Optical Society of America B-Optical Physics 26: 1384-1394

Forsgren N, Lamont RJ, Persson K (2009) Crystal structure of the variable domain of the Streptococcus gordonii surface protein SspB. Protein Science 18: 1896-1905

Forsgren N, Lamont RJ, Persson K (2009) A crystallizable form of the Streptococcus gordonii surface antigen SspB C-domain obtained by limited proteolysis. Acta Crystallographica Section F-Structural Biology Communications 65: 712-714

Fuhrmann J, Schmidt A, Spiess S, Lehner A, Turgay K, Mechtler K, Charpentier E, Clausen T (2009) McsB is a protein arginine kinase that phosphorylates and inhibits the heat-shock regulator CtsR. Science 324: 1323-1327

Guo B, Teneberg S, Mınch R, Terunuma D, Hatano K, Matsuoka K, Angström J, Borén T, Bergström S (2009) Relapsing fever Borrelia binds to neolacto glycans and mediates rosetting of human erythrocytes. Proc Natl Acad Sci U S A 106: 19280-19285

Hill J, Leary S, Smither S, Best A, Pettersson J, Forsberg Å, Lingard B, Lipka A, Brown KA, Williamson ED, Titball RW (2009) N255 is a key residue for recognition by a monoclonal antibody which protects against Yersinia pestis infection. Vaccine 27: 7073-7079

Holl K, Lundin E, Surcel HM, Grankvist K, Koskela P, Dillner J, Hallmans G, Wadell G, Olafsdottir GH, Ogmundsdottir HM, Pukkala E, Lehtinen M, Stattin P, Lukanova A (2009) Endogenous steroid hormone levels in early pregnancy and risk of testicular cancer in the offspring: A nested case-referent study. International Journal of Cancer 124: 2923-2928

Isaksson E, Aili M, Fahlgren A, Carlsson S, Rosqvist R, Wolf-Watz H (2009) The membrane localization domain is required for intracellular localization and autoregulation of YopE in Yersinia pseudotuberculosis. Infect Immun 77: 4740-4749

Ishikawa T, Rompikuntal PK, Lindmark B, Milton DL, Wai SN (2009) Quorum Sensing Regulation of the Two hcp Alleles in Vibrio cholerae O1 Strains. Plos One 4: 9

Jaenson TG, Eisen L, Comstedt P, Mejlon HA, Lindgren E, Bergström S, Olsen B (2009) Risk indicators for the tick Ixodes ricinus and Borrelia burgdorferi sensu lato in Sweden. Med Vet Entomol 23: 226-237

Johansson J (2009) RNA thermosensors in bacterial pathogens. Contrib Microbiol 16: 150-160

Johansson S, Nilsson E, Qian WX, Guilligay D, Crepin T, Cusack S, Arnberg N, Elofsson M (2009) Design, Synthesis, and Evaluation of N-Acyl Modified Sialic Acids as Inhibitors of Adenoviruses Causing Epidemic Keratoconjunctivitis. J Med Chem 52: 3666-3678

Jonsson M, Lenman A, Frängsmyr L, Nyberg C, Abdullahi M, Arnberg N (2009) Coagulation factors IX and X enhance binding and infection of adenovirus types 5 and 31 in human epithelial cells. J Virol 83: 3816-3825

Kadzhaev K, Zingmark C, Golovliov I, Bolanowski M, Shen H, Conlan W, Sjöstedt A (2009) Identification of genes contributing to the virulence of Francisella tularensis SCHU S4 in a mouse intradermal infection model. PLoS One 4: e5463

Kapadnis P, Hall E, Ramstedt M, Galloway W, Welch M, Spring D (2009) Towards quorum-quenching catalytic antibodies. Chemical Communications: 538-540

Kapeu AS, Luostarinen T, Jellum E, Dillner J, Hakama M, Koskela P, Lenner P, Love A, Mahlamaki E, Thoresen S, Tryggvadottir L, Wadell G, Youngman L, Lehtinen M (2009) Is Smoking an Independent Risk Factor for Invasive Cervical Cancer? A Nested Case-Control Study Within Nordic Biobanks. American Journal of Epidemiology 169: 480-488

Larsson C, Andersson M, Bergström S (2009) Current issues in relapsing fever. Curr Opin Infect Dis 22: 443-449

Larsson C, Lundqvist J, van Rooijen N, Bergström S (2009) A novel animal model of Borrelia recurrentis louse-borne relapsing fever borreliosis using immunodeficient mice. PLoS Negl Trop Dis 3: e522

Lindgren H, Honn M, Golovlev I, Kadzhaev K, Conlan W, Sjöstedt A (2009) The 58-kilodalton major virulence factor of Francisella tularensis is required for efficient utilization of iron. Infect Immun 77: 4429-4436

Lindmark B, Rompikuntal PK, Vaitkevicius K, Song T, Mizunoe Y, Uhlin BE, Guerry P, Wai SN (2009) Outer membrane vesicle-mediated release of cytolethal distending toxin (CDT) from Campylobacter jejuni. BMC Microbiol 9: 220

Loh E, Dussurget O, Gripenland J, Vaitkevicius K, Tiensuu T, Mandin P, Repoila F, Buchrieser C, Cossart P, Johansson J (2009) A trans-Acting Riboswitch Controls Expression of the Virulence Regulator PrfA in Listeria monocytogenes. Cell 139: 770-779

Lundberg E, Olofsson A, Westermark GT, Sauer-Eriksson AE (2009) Stability and fibril formation properties of human and fish transthyretin, and of the Escherichia coli transthyretin-related protein. Febs Journal 276: 1999-2011

Magalhaes A, Gomes J, David L, Haas R, Borén T, Reis C (2009) FUT2-Null Mice Show Impaired BabA-Mediated Adhesion of H. pylori to Gastric Mucosa. Helicobacter 14: 371-371

Magalhaes A, Gomes J, Ismail MN, Haslam SM, Mendes N, Osorio H, David L, Le Pendu J, Haas R, Dell A, Borén T, Reis CA (2009) Fut2-null mice display an altered glycosylation profile and impaired BabA-mediated Helicobacter pylori adhesion to gastric mucosa. Glycobiology 19: 1525-1536

Meibom KL, Forslund AL, Kuoppa K, Alkhuder K, Dubail I, Dupuis M, Forsberg Å, Charbit A (2009) Hfq, a novel pleiotropic regulator of virulence-associated genes in Francisella tularensis. Infect Immun 77: 1866-1880

Müller C, Åberg A, Straseviçiene J, Emody L, Uhlin B, Balsalobre C (2009) Type 1 fimbriae, a colonization factor of uropathogenic Escherichia coli, are controlled by the metabolic sensor CRP-cAMP. PLoS Pathog 5: e1000303

Najdenski H, Golkocheva-Markova E, Kussovski V, Vesselinova A, Garbom S, Wolf-Watz H (2009) Attenuation and preserved immunogenic potential of Yersinia pseudotuberculosis mutant strains evidenced in oral pig model. Zoonoses Public Health 56: 157-168

Naucler P, Ryd W, Tornberg S, Strand A, Wadell G, Elfgren K, Radberg T, Strander B, Forslund O, Hansson BG, Hagmar B, Johansson B, Rylander E, Dillner J (2009) Efficacy of HPV DNA Testing With Cytology Triage and/or Repeat HPV DNA Testing in Primary Cervical Cancer Screening. Journal of the National Cancer Institute 101: 88-99

Odenbreit S, Swoboda K, Barwig I, Ruhl S, Borén T, Koletzko S, Haas R (2009) Outer membrane protein expression profile in Helicobacter pylori clinical isolates. Infect Immun 77: 3782-3790

Olofsson A, Lindhagen-Persson M, Vestling M, Sauer-Eriksson AE, Öhman A (2009) Quenched hydrogen/deuterium exchange NMR characterization of amyloid-beta peptide aggregates formed in the presence of Cu2+ or Zn2+. Febs Journal 276: 4051-4060

Olofsson A, Sauer-Eriksson AE, Öhman A (2009) Amyloid fibril dynamics revealed by combined hydrogen/deuterium exchange and nuclear magnetic resonance. Analytical Biochemistry 385: 374-376

Ou GW, Hedberg M, Horstedt P, Baranov V, Forsberg G, Drobni M, Sandstrom O, Wai SN, Johansson I, Hammarström ML, Hernell O, Hammarström S (2009) Proximal Small Intestinal Microbiota and Identification of Rod-Shaped Bacteria Associated With Childhood Celiac Disease. American Journal of Gastroenterology 104: 3058-3067

Ou GW, Rompikuntal PK, Bitar A, Lindmark B, Vaitkevicius K, Wai SN, Hammarström ML (2009) Vibrio cholerae Cytolysin Causes an Inflammatory Response in Human Intestinal Epithelial Cells That Is Modulated by the PrtV Protease. Plos One 4: e7806

Ovchinnikova O, Gylfe A, Bailey L, Nordström A, Rudling M, Jung C, Bergström S, Waldenstrom A, Hansson GK, Nordström P (2009) Osteoprotegerin promotes fibrous cap formation in atherosclerotic lesions of ApoE-deficient mice--brief report. Arterioscler Thromb Vasc Biol 29: 1478-1480

Persson BD, Muller S, Reiter DM, Schmitt BBT, Marttila M, Sumowski CV, Schweizer S, Scheu U, Ochsenfeld C, Arnberg N, Stehle T (2009) An Arginine Switch in the Species B Adenovirus Knob Determines High-Affinity Engagement of Cellular Receptor CD46. Journal of Virology 83: 673-686

Petzold K, Olofsson A, Arnqvist A, Gröbner G, Schleucher J (2009) Semiconstant-Time P,H-COSY NMR: Analysis of Complex Mixtures of Phospholipids Originating from Helicobacter pylori. Journal of the American Chemical Society 131(40): 14150-14151

Pudelko M, Qian WX, Elofsson M (2009) Synthesis and application of N- 1-(4-(4-fluorophenyl)-2,6-dioxocyclohexylidene)ethyl (Fde)-protected amino acids for optimization of solid-phase peptide synthesis using gel-phase F-19 NMR spectroscopy. Journal of Peptide Science 15: 264-271

Ramstedt M, Ekstrand-Hammarstrom B, Shchukarev A, Bucht A, Osterlund L, Welch M, Huck W (2009) Bacterial and mammalian cell response to poly(3-sulfopropyl methacrylate) brushes loaded with silver halide salts. Biomaterials 30: 1524-1531

Rebetz J, Na M, Su C, Holmqvist B, Edqvist A, Nyberg C, Widegren B, Salford LG, Sjogren HO, Arnberg N, Qian Q, Fan X (2009) Fiber mediated receptor masking in non-infected bystander cells restricts adenovirus cell killing effect but promotes adenovirus host co-existence. PLoS One 4: e8484

Russmann H, Panthel K, Kohn B, Jellbauer S, Winter S, Garbom S, Wolf-Watz H, Hoffmann S, Grauling-Halama S, Geginat G (2009) Alternative endogenous protein processing via an autophagy-dependent pathway compensates for Yersinia-mediated inhibition of endosomal MHC II antigen presentation. International Journal of Medical Microbiology 299: 35-35

Rydén P, Sjöstedt A, Johansson A (2009) Effects of climate change on tularaemia disease activity in Sweden. Glob Health Action 2

Salomonsson E, Forsberg Å, Roos N, Holz C, Maier B, Koomey M, Winther-Larsen HC (2009) Functional analyses of pilin-like proteins from Francisella tularensis: complementation of type IV pilus phenotypes in Neisseria gonorrhoeae. Microbiology 155: 2546-2559

Salomonsson E, Kuoppa K, Forslund A, Zingmark C, Golovliov I, Sjöstedt A, Noppa L, Forsberg Å (2009) Reintroduction of two deleted virulence loci restores full virulence to the live vaccine strain of Francisella tularensis. Infect Immun 77: 3424-3431

Sellstedt M, Almqvist F (2009) A Novel Heterocyclic Scaffold Formed by Ring Expansion of a Cyclic Sulfone to Sulfonamides. Organic Letters 11: 5470-5472

Shao J, Lathdavong L, Kluczynski P, Lundqvist S, Axner O (2009) Methodology for temperature measurements in water vapor using wavelength-modulation tunable diode laser absorption spectrometry in the telecom C-band. Applied Physics B-Lasers and Optics 97: 727-748

Sjöström A, Balsalobre C, Emödy L, Westerlund-Wikström B, Hacker J, Uhlin B (2009) The SfaXII protein from newborn meningitis E. coli is involved in regulation of motility and type 1 fimbriae expression. Microb Pathog 46: 243-252

Sjöstrom AE, Sonden B, Müller C, Rydstrom A, Dobrindt U, Wai SN, Uhlin BE (2009) Analysis of the sfaX(II) locus in the Escherichia coli meningitis isolate IHE3034 reveals two novel regulatory genes within the promoter-distal region of the main S fimbrial operon. Microbial Pathogenesis 46: 150-158

Song TY, Wai SN (2009) A novel sRNA that modulates virulence and environmental fitness of Vibrio cholerae. Rna Biology 6: 254-258

Spjut S, Pudelko M, Hartmann M, Elofsson M (2009) Carbamate Linker Strategy in Solid-Phase Synthesis of Amino-Functionalized Glycoconjugates for Attachment to Solid Surfaces and Investigation of Protein-Carbohydrate Interactions. European Journal of Organic Chemistry: 349-357

Steptoe A, Gylfe A, Shamaei-Tousi A, Bergström S, Henderson B (2009) Pathogen burden and cortisol profiles over the day. Epidemiol Infect 137: 1816-1824

Straskova A, Pavkova I, Link M, Forslund AL, Kuoppa K, Noppa L, Kroca M, Fucikova A, Klimentova J, Krocova Z, Forsberg Å, Stulik J (2009) Proteome analysis of an attenuated Francisella tularensis dsbA mutant: identification of potential DsbA substrate proteins. J Proteome Res 8: 5336-5346

Sundin C, Elofsson M, Wolf-Watz H, Rosell S (2009) [Virulence blocking antibiotics. Anti-bacterial agents with completely new action mechanisms]. Lakartidningen 106: 2543-2545

Talyzina NM, Ingvarsson PK, Zhu J, Wai SN, Andersson A (2009) Molecular diversification in the quorum-sensing system of Vibrio cholerae: Role of natural selection in the emergence of pandemic strains. Appl Environ Microbiol 75: 3808-3812

Toledo-Arana A, Dussurget O, Nikitas G, Sesto N, Guet-Revillet H, Balestrino D, Loh E, Gripenland J, Tiensuu T, Vaitkevicius K, Barthelemy M, Vergassola M, Nahori MA, Soubigou G, Regnault B, Coppee JY, Lecuit M, Johansson J, Cossart P (2009) The Listeria transcriptional landscape from saprophytism to virulence. Nature 459: 950-956

Tree JJ, Wang D, McInally C, Mahajan A, Layton A, Houghton I, Elofsson M, Stevens MP, Gally DL, Roe AJ (2009) Characterization of the Effects of Salicylidene Acylhydrazide Compounds on Type III Secretion in Escherichia coli O157:H7. Infection and Immunity 77: 4209-4220

Trmcic-Cvitas J, Hasan E, Ramstedt M, Li X, Cooper MA, Abell C, Huck WTS, Gautrot JE (2009) Biofunctionalized Protein Resistant Oligo(ethylene glycol)-Derived Polymer Brushes as Selective Immobilization and Sensing Platforms. Biomacromolecules 10: 2885-2894

Tuomisto J, Holl K, Rantakokko P, Koskela P, Hallmans G, Wadell G, Stattin P, Dillner J, Ogmundsdottir HM, Vartiainen T, Lehtinen M, Pukkala E (2009) Maternal smoking during pregnancy and testicular cancer in the sons: A nested case-control study and a meta-analysis. European Journal of Cancer 45: 1640-1648

Urban CF, Ermert D, Schmid M, Abu-Abed U, Goosmann C, Nacken W, Brinkmann V, Jungblut PR, Zychlinsky A (2009) Neutrophil extracellular traps contain calprotectin, a cytosolic protein complex involved in host defense against Candida albicans. Plos Pathogens 5: e1000649

Valeru SP, Rompikuntal PK, Ishikawa T, Vaitkevicius K, Sjöling A, Dolganov N, Zhu J, Schoolnik G, Wai SN (2009) Role of melanin pigment in expression of Vibrio cholerae virulence factors. Infect Immun 77: 935-42

van Poll M, Khodabakhsh S, Brewer P, Shard A, Ramstedt M, Huck W (2009) Surface modification of PDMS via self-organization of vinyl-terminated small molecules. Soft Matter 5: 2286-2293

Walz A, Odenbreit S, Stuhler K, Wattenberg A, Meyer HE, Mahdavi J, Borén T, Ruhl S (2009) Identification of glycoprotein receptors within the human salivary proteome for the lectin-like BabA and SabA adhesins of Helicobacter pylori by fluorescence-based 2-D bacterial overlay. Proteomics 9: 1582-1592

Weber B, Hasic M, Chen C, Wai SN, Milton DL (2009) Type VI secretion modulates quorum sensing and stress response in Vibrio anguillarum. Environmental Microbiology 11: 3018-3028

Widhe M, Ekerfelt C, Jarefors S, Skogman BH, Peterson EM, Bergström S, Forsberg P, Ernerudh J (2009) T-cell epitope mapping of the Borrelia garinii outer surface protein A in lyme neuroborreliosis. Scandinavian journal of immunology 70: 141-148

Publikationer 2008

Aili M, Isaksson EL, Carlsson SE, Wolf-Watz H, Rosqvist R, Francis MS (2008) Regulation of Yersinia Yop-effector delivery by translocated YopE. Int J Med Microbiol 298: 183-92

Andersson H, Gustafsson M, Olsson R, Almqvist F (2008) Selective synthesis of 2-substituted pyridine N-oxides via directed ortho-metallation using Grignard reagents. Tetrahedron Letters 49: 6901-6903

Andersson M, Axner O, Almqvist F, Uhlin BE, Fällman E (2008) Physical properties of biopolymers assessed by optical tweezers: Analysis of folding and refolding of bacterial pili. Chemphyschem 9: 221-235

Axner O, Ma WG, Foltynowicz A (2008) Sub-Doppler dispersion and noise-immune cavity-enhanced optical heterodyne molecular spectroscopy revised. Journal of the Optical Society of America B-Optical Physics 25: 1166-1177

Azevedo M, Eriksson S, Mendes N, Serpa J, Figueiredo C, Resende LP, Ruvoen-Clouet N, Haas R, Borén T, Le Pendu J, David L (2008) Infection by Helicobacter pylori expressing the BabA adhesin is influenced by the secretor phenotype. Journal of Pathology 215: 308-316

Bailey L, Engström P, Nordström A, Bergström S, Waldenström A, Nordström P (2008) Chlamydia pneumoniae infection results in generalized bone loss in mice. Microbes and Infection 10: 1175-1181

Berg V, Das P, Chorell E, Hedenstrom M, Pinkner JS, Hultgren SJ, Almqvist F (2008) Carboxylic acid isosteres improve the activity of ring-fused 2-pyridones that inhibit pilus biogenesis in E. coli. Bioorg Med Chem Lett 18: 3536-3540

Björnham O, Axner O, Andersson M (2008) Modeling of the elongation and retraction of Escherichia coli P pili under strain by Monte Carlo simulations. European Biophysics Journal with Biophysics Letters 37: 381-391

Bönquist L, Lindgren H, Golovliov I, Guina T, Sjöstedt A (2008) MglA and Igl proteins contribute to the modulation of Francisella tularensis live vaccine strain-containing phagosomes in murine macrophages. Infect Immun 76: 3502-3510

Bruce MG, Deeks SL, Zulz T, Bruden D, Navarro C, Lovgren M, Jette L, Kristinsson K, Sigmundsdottir G, Jensen KB, Lovoll O, Nuorti JP, Herva E, Nystedt A, Sjöstedt A, Koch A, Hennessy TW, Parkinson AJ (2008) International Circumpolar Surveillance System for invasive pneumococcal disease, 1999-2005. Emerg Infect Dis 14: 25-33

Bunikis I, Denker K, Östberg Y, Andersen C, Benz R, Bergström S (2008) An RND-type efflux system in Borrelia burgdorferi is involved in virulence and resistance to antimicrobial compounds. PLoS Pathog 4: e1000009

Conlan JW, Zhao X, Harris G, Shen H, Bolanowski M, Rietz C, Sjöstedt A, Chen W (2008) Molecular immunology of experimental primary tularemia in mice infected by respiratory or intradermal routes with type A Francisella tularensis. Mol Immunol 45: 2962-2969

Demuth A, Aharonowitz Y, Bachmann TT, Blum-Oehler G, Buchrieser C, Covacci A, Dobrindt U, Emody L, van der Ende A, Ewbank J, Fernandez LA, Frosch M, Garcia-del Portillo F, Gilmore MS, Glaser P, Goebel W, Hasnain SE, Heesemann J, Islam K, Korhonen Maiden M, Meyer TF, Montecucco, C, Oswald E, Parkhill J,Pucciarelli MG, Ron E, Svanborg C, Uhlin BE, Wai SN, Wehland J, Hacker J (2008). Pathogenomics: An updated European Research Agenda. Infection Genetics and Evolution 8: 386-393

Eliasson H, Olcen P, Sjöstedt A, Jurstrand M, Back E, Andersson S (2008) Kinetics of the immune response associated with tularemia: comparison of an enzyme-linked immunosorbent assay, a tube agglutination test, and a novel whole-blood lymphocyte stimulation test. Clin Vaccine Immunol 15: 1238-1243

Fernebro J, Blomberg C, Morfeldt E, Wolf-Watz H, Normark S, Normark BH (2008) The influence of in vitro fitness defects on pneumococcal ability to colonize and to cause invasive disease. BMC Microbiol 8: 65

Foltynowicz A, Ma WG, Axner O (2008) Characterization of fiber-laser-based sub-Doppler NICE-OHMS for quantitative trace gas detection. Optics Express 16: 14689-14702

Foltynowicz A, Ma WG, Schmidt FM, Axner O (2008) Doppler-broadened noise-immune cavity-enhanced optical heterodyne molecular spectrometry signals from optically saturated transitions under low pressure conditions. Journal of the Optical Society of America B-Optical Physics 25: 1156-1165

Foltynowicz A, Schmidt FM, Ma W, Axner O (2008) Noise-immune cavity-enhanced optical heterodyne molecular spectroscopy: Current status and future potential. Applied Physics B-Lasers and Optics 92: 313-326

Galka F, Wai SN, Kusch H, Engelmann S, Hecker M, Schmeck B, Hippenstiel S, Uhlin BE, Steinert M (2008) Proteomic characterization of the whole secretome of Legionella pneumophila and functional analysis of outer membrane vesicles. Infection and Immunity 76: 1825-1836

Holl K, Surcel HM, Koskela P, Dillner J, Hallmans G, Wadell G, Kaasila M, Olafsdottir GH, Ogmundsdottir HM, Pukkala E, Stattin P, Lehtinen M (2008) Maternal Epstein-Barr virus and cytomegalovirus infections and risk of testicular cancer in the offspring: a nested case-control study. Apmis 116: 816-822

Karched M, Ihalin R, Eneslatt K, Zhong DY, Oscarsson J, Wai SN, Chen C, Asikainen SE (2008) Vesicle-independent extracellular release of a proinflammatory outer membrane lipoprotein in free-soluble form. Bmc Microbiology 8: 18

Kelk P, Claesson R, Chen C, Sjöstedt A, Johansson A (2008) IL-1beta secretion induced by Aggregatibacter (Actinobacillus) actinomycetemcomitans is mainly caused by the leukotoxin. Int J Med Microbiol 298: 529-541

Keyser P, Elofsson M, Rosell S, Wolf-Watz H (2008) Virulence blockers as alternatives to antibiotics: type III secretion inhibitors against Gram-negative bacteria. J Intern Med 264: 17-29

Kumlin U, Olofsson S, Dimock K, Arnberg N (2008) Sialic acid tissue distribution and influenza virus tropism. Influenza Other Respi Viruses 2: 147-154

Larsson C, Bergström S (2008) A novel and simple method for laboratory diagnosis of relapsing Fever borreliosis. Open Microbiol J 2: 10-12

Larsson C, Lundqvist J, Bergström S (2008) Residual brain infection in murine relapsing fever borreliosis can be successfully treated with ceftriaxone. Microb Pathog 44: 262-264

Lindberg S, Xia Y, Sondén B, Göransson M, Hacker J, Uhlin BE (2008) Regulatory Interactions among adhesin gene systems of uropathogenic Escherichia coli. Infect Immun 76: 771-780

Lindén S, Mahdavi J, Semino-Mora C, Olsen C, Carlstedt I, Borén T, Dubois A (2008) Role of ABO secretor status in mucosal innate immunity and H. pylori infection. PLoS Pathog 4: e2

Lofling J, Diswall M, Eriksson S, Borén T, Breimer ME, Holgersson J (2008) Studies of Lewis antigens and H. pylori adhesion in CHO cell lines engineered to express Lewis b determinants. Glycobiology 18: 494-501

Lukanova A, Andersson R, Wulff M, Zeleniuch-Jacquotte A, Grankvist K, Dossus L, Afanasyeva Y, Johansson R, Arslan AA, Lenner P, Wadell G, Hallmans G, Toniolo P, Lundin E (2008) Human Chorionic Gonadotropin and Alpha-Fetoprotein Concentrations in Pregnancy and Maternal Risk of Breast Cancer: A Nested Case-Control Study. American Journal of Epidemiology 168: 1284-1291

Ma WG, Foltynowicz A, Axner O (2008) Theoretical description of Doppler-broadened noise-immune cavity-enhanced optical heterodyne molecular spectroscopy under optically saturated conditions. Journal of the Optical Society of America B-Optical Physics 25: 1144-1155

Meibom KL, Dubail I, Dupuis M, Barel M, Lenco J, Stulik J, Golovliov I, Sjöstedt A, Charbit A (2008) The heat-shock protein ClpB of Francisella tularensis is involved in stress tolerance and is required for multiplication in target organs of infected mice. Mol Microbiol 67: 1384-13401

Meinzer U, Esmiol-Welterlin S, Barreau F, Berrebi D, Dussaillant M, Bonacorsi S, Chareyre F, Niwa-Kawakita M, Alberti C, Sterkers G, Lesuffleur T, Peuchmaur M, Karin M, Eckmann L, Giovannini M, Ollendorff V, Wolf-Watz H, Hugot JP (2008) CARD15/NOD2 mediates susceptibility to Yersinia pseudotuberculosis. Gastroenterology 134: A651-A651

Meinzer U, Esmiol-Welterlin S, Barreau F, Berrebi D, Dussaillant M, Bonacorsi S, Chareyre F, Niwa-Kawakita M, Alberti C, Sterkers G, Villard C, Lesuffleur T, Peuchmaur M, Karin M, Eckmann L, Giovannini M, Ollendorff V, Wolf-Watz H, Hugot JP (2008) Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice. PLoS One 3: e2769

Morgado I, Melo EP, Lundberg E, Estrela NL, Sauer-Eriksson AE, Power DM (2008) Hormone affinity and fibril formation of piscine transthyretin: The role of the N-terminal. Molecular and Cellular Endocrinology 295: 48-58

Nilsson EC, Jamshidi F, Johansson SMC, Oberste MS, Arnberg N (2008) Sialic acid is a cellular receptor for coxsackievirus A24 variant, an emerging virus with pandemic potential. Journal of Virology 82: 3061-3068

Ovchinnikova O, Gylfe A, Bailey L, Bergström S, Rudling M, Waldenstrom A, Hansson GK, Nordstrom P (2008) Osteoprotegerin promotes fibrous cap formation in atherosclerotic lesions of apoe deficient mice. Scandinavian journal of immunology 68: 199-200

Pemberton N, Pinkner JS, Edvinsson S, Hultgren SJ, Almqvist F (2008) Synthesis and evaluation of dihydroimidazolo and dihydrooxazolo ring-fused 2-pyridones - targeting pilus biogenesis in uropathogenic bacteria. Tetrahedron 64: 9368-9376

Sabouri N, Viberg J, Goyal DK, Johansson E, Chabes A (2008) Evidence for lesion bypass by yeast replicative DNA polymerases during DNA damage. Nucleic Acids Research 36: 5660-5667

Selimi DA, Peng Q, Charkowski AO, Yang C, Elofsson M (2008) Identification of a type three secretion inhibitor shared by Dickeya dadantii and Yersinia pseudotuberculosis. Phytopathology 98: S143-S143

Sellstedt M, Almqvist F (2008) Synthesis of a novel tricyclic peptidomimetic scaffold. Organic Letters 10: 4005-4007

Song T, Mika F, Lindmark B, Liu Z, Schild S, Bishop A, Zhu J, Camilli A, Johansson J, Vogel J, Wai SN (2008) A new Vibrio cholerae sRNA modulates colonization and affects release of outer membrane vesicles. Mol Microbiol 70: 100-111

Tano K, von Essen R, Eriksson PO, Sjöstedt A (2008) Alloiococcus otitidis--otitis media pathogen or normal bacterial flora? APMIS 116: 785-90

Thein M, Bunikis I, Denker K, Larsson C, Cutler S, Drancourt M, Schwan TG, Mentele R, Lottspeich F, Bergström S, Benz R (2008) Oms38 Is the First Identified Pore-Forming Protein in the Outer Membrane of Relapsing Fever Spirochetes. Journal of Bacteriology 190: 7035-7042

Tuomisto J, Holl K, Rantakokko P, Koskela P, Hallmans G, Wadell G, Stattin P, Dillner J, Ogmundsdottir HM, Vartiainen T, Lehtinen M, Pukkala E (2008) Maternal smoking during pregnancy, and testicular cancer in the offspring. Toxicology Letters 180: S163-S163

Vaitkevicius K, Rompikuntal PK, Lindmark B, Vaitkevicius R, Song TY, Wai SN (2008) The metalloprotease PrtV from Vibrio cholerae. Febs Journal 275: 3167-3177

Vonkavaara M, Telepnev M, Rydén P, Sjöstedt A, Stöven S (2008) Drosophila melanogaster as a model for elucidating the pathogenicity of Francisella tularensis. Cell Microbiol 10: 1327-1338

Walz A, Odenbreit S, Stuhler K, Meyer HE, Wattenberg A, Mahdavi J, Borén T, Ruhl S (2008) Glycoprotein Receptors within the Human Salivary Proteome for the Lectin-like BabA and SabA Adhesins of Helicobacter pylori. Glycobiology 18: 1003-1003

Weber B, Croxatto A, Chen C, Milton DL (2008) RpoS induces expression of the Vibrio anguillarum quorum-sensing regulator VanT. Microbiol-Sgm 154: 767-780

Publikationer 2007

Andersson, H., Almqvist, F., and Olsson, R. (2007). Synthesis of 2-substituted pyridines via a regiospecific alkylation, alkynylation, and arylation of pyridine N-oxides. Org Lett 9, 1335-1337.

Andersson, M., Nordstrand, A., Shamaei-Tousi, A., Jansson, A., Bergström, S., and Guo, B. (2007). In situ immune response in brain and kidney during early relapsing fever borreliosis. J Neuroimmunol 183, 26-32.

Bailey, L., Gylfe, A., Sundin, C., Muschiol, S., Elofsson, M., Nordström, P., Henriques-Normark, B., Lugert, R., Waldenström, A., Wolf-Watz, H., et al. (2007). Small molecule inhibitors of type III secretion in Yersinia block the Chlamydia pneumoniae infection cycle. FEBS Lett 581, 587-595.

Bröms, J., Francis, M., and Forsberg, A. (2007). Diminished LcrV secretion attenuates Yersinia pseudotuberculosis virulence. J Bacteriol 189, 8417-8429.

Carlsson, K., Liu, J., Edqvist, P., and Francis, M. (2007). Extracytoplasmic-stress-responsive pathways modulate type III secretion in Yersinia pseudotuberculosis. Infect Immun 75, 3913-3924.

Carlsson, K., Liu, J., Edqvist, P., and Francis, M. (2007). Influence of the Cpx extracytoplasmic-stress-responsive pathway on Yersinia sp.-eukaryotic cell contact. Infect Immun 75, 4386-4399.

Chorell, E., Das, P., and Almqvist, F. (2007). Diverse functionalization of thiazolo ring-fused 2-pyridones. J Org Chem 72, 4917-4924.

Croxatto, A., Lauritz, J., Chen, C., and Milton, D. (2007). Vibrio anguillarum colonization of rainbow trout integument requires a DNA locus involved in exopolysaccharide transport and biosynthesis. Environ Microbiol 9, 370-382.

Dahlgren, M., Kauppi, A., Olsson, I., Linusson, A., and Elofsson, M. (2007). Design, synthesis, and multivariate quantitative structure-activity relationship of salicylanilides--potent inhibitors of type III secretion in Yersinia. J Med Chem 50, 6177-6188.

Edqvist, P., Aili, M., Liu, J., and Francis, M. (2007). Minimal YopB and YopD translocator secretion by Yersinia is sufficient for Yop-effector delivery into target cells. Microbes Infect 9, 224-233.

Fijolek, A., Hofer, A., and Thelander, L. (2007). Expression, purification, characterization, and in vivo targeting of trypanosome CTP synthetase for treatment of African sleeping sickness. J Biol Chem 282, 11858-11865.

Forsberg, A., and Guina, T. (2007). Type II secretion and type IV pili of Francisella. Ann N Y Acad Sci 1105, 187-201.

Garbom, S., Olofsson, M., Björnfot, A., Srivastava, M., Robinson, V., Oyston, P., Titball, R., and Wolf-Watz, H. (2007). Phenotypic characterization of a virulence-associated protein, VagH, of Yersinia pseudotuberculosis reveals a tight link between VagH and the type III secretion system. Microbiology 153, 1464-1473.

Hainzl, T., Huang, S., and Sauer-Eriksson, A. (2007). Interaction of signal-recognition particle 54 GTPase domain and signal-recognition particle RNA in the free signal-recognition particle. Proc Natl Acad Sci U S A 104, 14911-14916.

Johansson, C., Jonsson, M., Marttila, M., Persson, D., Fan, X., Skog, J., Frängsmyr, L., Wadell, G., and Arnberg, N. (2007). Adenoviruses use lactoferrin as a bridge for CAR-independent binding to and infection of epithelial cells. J Virol 81, 954-963.

Johansson, S., Nilsson, E., Elofsson, M., Ahlskog, N., Kihlberg, J., and Arnberg, N. (2007). Multivalent sialic acid conjugates inhibit adenovirus type 37 from binding to and infecting human corneal epithelial cells. Antiviral Res 73, 92-100.

Karlsson, A., and Sauer-Eriksson, A. (2007). Heating of proteins as a means of improving crystallization: a successful case study on a highly amyloidogenic triple mutant of human transthyretin. Acta Crystallogr Sect F Struct Biol Cryst Commun 63, 695-700.

Kauppi, A., Andersson, C., Norberg, H., Sundin, C., Linusson, A., and Elofsson, M. (2007). Inhibitors of type III secretion in Yersinia: design, synthesis and multivariate QSAR of 2-arylsulfonylamino-benzanilides. Bioorg Med Chem 15, 6994-7011.

Klein, M., Andersson, M., Axner, O., and Fällman, E. (2007). Dual-trap technique for reduction of low-frequency noise in force measuring optical tweezers. Appl Opt 46, 405-412.

Larsson, C., Comstedt, P., Olsen, B., and Bergström, S. (2007). First record of Lyme disease Borrelia in the Arctic. Vector Borne Zoonotic Dis 7, 453-456.

Lavander, M., Ericsson, S., Bröms, J., and Forsberg, A. (2007). Twin arginine translocation in Yersinia. Adv Exp Med Biol 603, 258-267.

Lindgren, H., Shen, H., Zingmark, C., Golovliov, I., Conlan, W., and Sjöstedt, A. (2007). Resistance of Francisella tularensis strains against reactive nitrogen and oxygen species with special reference to the role of KatG. Infect Immun 75, 1303-1309.

Nordstrand, A., Bunikis, I., Larsson, C., Tsogbe, K., Schwan, T., Nilsson, M., and Bergström, S. (2007). Tickborne relapsing fever diagnosis obscured by malaria, Togo. Emerg Infect Dis 13, 117-123.

Olofsson, A., Borowik, T., Gröbner, G., and Sauer-Eriksson, A. (2007). Negatively charged phospholipid membranes induce amyloid formation of medin via an alpha-helical intermediate. J Mol Biol 374, 186-194.

Ottmann, C., Yasmin, L., Weyand, M., Veesenmeyer, J.L., Diaz, M.H., Palmer, R.H., Francis, M.S., Hauser, A.R., Wittinghofer, A., and Hallberg, B. (2007). Phosphorylation-independent interaction between 14-3-3 and exoenzyme S: from structure to pathogenesis. EMBO J 26, 902-913.

Pinne, M., Thein, M., Denker, K., Benz, R., Coburn, J., and Bergström, S. (2007). Elimination of channel-forming activity by insertional inactivation of the p66 gene in Borrelia burgdorferi. FEMS Microbiol Lett 266, 241-249.

Pudelko, M., Kihlberg, J., and Elofsson, M. (2007). Application of gel-phase 19F NMR spectroscopy for optimization of solid-phase synthesis of a hydrophobic peptide from the signal sequence of the mucin MUC1. J Pept Sci 13, 354-361.

Sjöstedt, A. (2007). Tularemia: history, epidemiology, pathogen physiology, and clinical manifestations. Ann N Y Acad Sci 1105, 1-29.

Skog, J., Edlund, K., Bergenheim, A., and Wadell, G. (2007). Adenoviruses 16 and CV23 efficiently transduce human low-passage brain tumor and cancer stem cells. Mol Ther 15, 2140-2145.

Szalewska-Palasz, A., Johansson, L., Bernardo, L., Skärfstad, E., Stec, E., Brännström, K., and Shingler, V. (2007). Properties of RNA polymerase bypass mutants: implications for the role of ppGpp and its co-factor DksA in controlling transcription dependent on sigma54. J Biol Chem 282, 18046-18056.

Wallner, F., Spjut, S., Boström, D., and Elofsson, M. (2007). Synthesis and evaluation of 2-(2-fluoro-4-hydroxymethyl-5-methoxy-phenoxy)acetic acid as a linker in solid-phase synthesis monitored by gel-phase (19)F NMR spectroscopy. Org Biomol Chem 5, 2464-2471.

Östberg, Y., Berg, S., Comstedt, P., Wieslander, A., and Bergström, S. (2007). Functional analysis of a lipid galactosyltransferase synthesizing the major envelope lipid in the Lyme disease spirochete Borrelia burgdorferi. FEMS Microbiol Lett 272, 22-29

Åberg, V., Fällman, E., Axner, O., Uhlin, B., Hultgren, S., and Almqvist, F. (2007). Pilicides regulate pili expression in E. coli without affecting the functional properties of the pilus rod. Mol Biosyst 3, 214-218 (Highlighted in Chemical Biology (2007), 2, B18)

Åberg, V., and Almqvist, F. (2007). Pilicides-small molecules targeting bacterial virulence. Org Biomol Chem 5, 1827-1834.

Publikationer 2006

Aberg, A., Shingler, V., and Balsalobre, C. (2006). (p)ppGpp regulates type 1 fimbriation of Escherichia coli by modulating the expression of the site-specific recombinase FimB. Mol Microbiol 60, 1520-1533.

Aili, M., Isaksson, E., Hallberg, B., Wolf-Watz, H., and Rosqvist, R. (2006). Functional analysis of the YopE GTPase-activating protein (GAP) activity of Yersinia pseudotuberculosis. Cell Microbiol 8, 1020-1033.

Andersson, H., Hartmanová, B., Bäck, E., Eliasson, H., Landfors, M., Näslund, L., Rydén, P., and Sjöstedt, A. (2006). Transcriptional profiling of the peripheral blood response during tularemia. Genes Immun 7, 503-513.

Andersson, H., Hartmanová, B., Rydén, P., Noppa, L., Näslund, L., and Sjöstedt, A. (2006). A microarray analysis of the murine macrophage response to infection with Francisella tularensis LVS. J Med Microbiol 55, 1023-1033.

Andersson, M., Fällman, E., Uhlin, B., and Axner, O. (2006). Dynamic force spectroscopy of E. coli P pili. Biophys J 91, 2717-2725.

Andersson, M., Fällman, E., Uhlin, B., and Axner, O. (2006). A sticky chain model of the elongation and unfolding of Escherichia coli P pili under stress. Biophys J 90, 1521-1534.

Aspholm, M., Kalia, A., Ruhl, S., Schedin, S., Arnqvist, A., Lindén, S., Sjöström, R., Gerhard, M., Semino-Mora, C., Dubois, A., et al. (2006). Helicobacter pylori adhesion to carbohydrates. Methods Enzymol 417, 293-339.

Aspholm, M., Olfat, F., Nordén, J., Sondén, B., Lundberg, C., Sjöström, R., Altraja, S., Odenbreit, S., Haas, R., Wadström, T., et al. (2006). SabA is the H. pylori hemagglutinin and is polymorphic in binding to sialylated glycans. PLoS Pathog 2, e110.

Axner, O., Schmidt, F., Foltynowicz, A., Gustafsson, J., Omenetto, N., and Winefordner, J. (2006). Absorption spectrometry by narrowband light in optically saturated and optically pumped collision and Doppler broadened gaseous media under arbitrary optical thickness conditions. Appl Spectrosc 60, 1217-1240.

Balsalobre, C., Johansson, J., and Uhlin, B. (2006). Cyclic AMP-dependent osmoregulation of crp gene expression in Escherichia coli. J Bacteriol 188, 5935-5944.

Balsalobre, C., Silván, J., Berglund, S., Mizunoe, Y., Uhlin, B., and Wai, S. (2006). Release of the type I secreted alpha-haemolysin via outer membrane vesicles from Escherichia coli. Mol Microbiol 59, 99-112.

Berglin, E., Johansson, T., Sundin, U., Jidell, E., Wadell, G., Hallmans, G., and Rantapää-Dahlqvist, S. (2006). Radiological outcome in rheumatoid arthritis is predicted by presence of antibodies against cyclic citrullinated peptide before and at disease onset, and by IgA-RF at disease onset. Ann Rheum Dis 65, 453-458.

Bernardo, L., Johansson, L., Solera, D., Skärfstad, E., and Shingler, V. (2006). The guanosine tetraphosphate (ppGpp) alarmone, DksA and promoter affinity for RNA polymerase in regulation of sigma-dependent transcription. Mol Microbiol 60, 749-764.

Bröms, J., Edqvist, P., Forsberg, A., and Francis, M. (2006). Tetratricopeptide repeats are essential for PcrH chaperone function in Pseudomonas aeruginosa type III secretion. FEMS Microbiol Lett 256, 57-66.

Buchholtz, C., Nielsen, K., Milton, D., Larsen, J., and Gram, L. (2006). Profiling of acylated homoserine lactones of Vibrio anguillarum in vitro and in vivo: Influence of growth conditions and serotype. Syst Appl Microbiol 29, 433-445.

Comstedt, P., Bergström, S., Olsen, B., Garpmo, U., Marjavaara, L., Mejlon, H., Barbour, A., and Bunikis, J. (2006). Migratory passerine birds as reservoirs of Lyme borreliosis in Europe. Emerg Infect Dis 12, 1087-1095.

del Peso-Santos, T., Bartolomé-Martín, D., Fernández, C., Alonso, S., García, J., Díaz, E., Shingler, V., and Perera, J. (2006). Coregulation by phenylacetyl-coenzyme A-responsive PaaX integrates control of the upper and lower pathways for catabolism of styrene by Pseudomonas sp. strain Y2. J Bacteriol 188, 4812-4821.

Drobni, M., Olsson, I., Eriksson, C., Almqvist, F., and Strömberg, N. (2006). Multivariate design and evaluation of a set of RGRPQ-derived innate immunity peptides. J Biol Chem 281, 15164-15171.

Edqvist, P., Bröms, J., Betts, H., Forsberg, A., Pallen, M., and Francis, M. (2006). Tetratricopeptide repeats in the type III secretion chaperone, LcrH: their role in substrate binding and secretion. Mol Microbiol 59, 31-44.

Galán, J., and Wolf-Watz, H. (2006). Protein delivery into eukaryotic cells by type III secretion machines. Nature 444, 567-573.

Gustafsson, D., Segerman, A., Lindman, K., Mei, Y., and Wadell, G. (2006). The Arg279Gln [corrected] substitution in the adenovirus type 11p (Ad11p) fiber knob abolishes EDTA-resistant binding to A549 and CHO-CD46 cells, converting the phenotype to that of Ad7p. J Virol 80, 1897-1905.

Holmfeldt, P., Brännström, K., Stenmark, S., and Gullberg, M. (2006). Aneugenic activity of Op18/stathmin is potentiated by the somatic Q18-->e mutation in leukemic cells. Mol Biol Cell 17, 2921-2930.

Kouokam, J., Wai, S., Fällman, M., Dobrindt, U., Hacker, J., and Uhlin, B. (2006). Active cytotoxic necrotizing factor 1 associated with outer membrane vesicles from uropathogenic Escherichia coli. Infect Immun 74, 2022-2030.

Kouokam JC, W.S. (2006). Outer membrane vesicle-mediated export of a pore-forming cytotoxin from Escherichia coli. . Toxin Reviews 25, 31-46.

Larsson, C., Andersson, M., Guo, B., Nordstrand, A., Hagerstrand, I., Carlsson, S., and Bergstrom, S. (2006). Complications of pregnancy and transplacental transmission of relapsing-fever borreliosis. J Infect Dis 194, 1367-1374.

Larsson, C., Andersson, M., Pelkonen, J., Guo, B., Nordstrand, A., and Bergström, S. (2006). Persistent brain infection and disease reactivation in relapsing fever borreliosis. Microbes Infect 8, 2213-2219.

Lindström, A., Pettersson, F., Almqvist, F., Berglund, A., Kihlberg, J., and Linusson, A. (2006). Hierarchical PLS modeling for predicting the binding of a comprehensive set of structurally diverse protein-ligand complexes. J Chem Inf Model 46, 1154-1167.

Loh, E., Gripenland, J., and Johansson, J. (2006). Control of Listeria monocytogenes virulence by 5'-untranslated RNA. Trends Microbiol 14, 294-298.

Lundberg, E., Bäckström, S., Sauer, U., and Sauer-Eriksson, A. (2006). The transthyretin-related protein: structural investigation of a novel protein family. J Struct Biol 155, 445-457.

Milton, D. (2006). Quorum sensing in vibrios: complexity for diversification. Int J Med Microbiol 296, 61-71.

Muschiol, S., Bailey, L., Gylfe, A., Sundin, C., Hultenby, K., Bergström, S., Elofsson, M., Wolf-Watz, H., Normark, S., and Henriques Normark, B. (2006). A small-molecule inhibitor of type III secretion inhibits different stages of the infectious cycle of Chlamydia trachomatis. Proc Natl Acad Sci U S A 103, 14566-14571.

Müller, C., Dobrindt, U., Nagy, G., Emödy, L., Uhlin, B., and Hacker, J. (2006). Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli. J Bacteriol 188, 5428-5438.

Paul-Satyaseela, M., Karched, M., Bian, Z., Ihalin, R., Borén, T., Arnqvist, A., Chen, C., and Asikainen, S. (2006). Immunoproteomics of Actinobacillus actinomycetemcomitans outer-membrane proteins reveal a highly immunoreactive peptidoglycan-associated lipoprotein. J Med Microbiol 55, 931-942.

Pemberton, N., Jakobsson, L., and Almqvist, F. (2006). Synthesis of multi ring-fused 2-pyridones via an acyl-ketene imine cyclocondensation. Org Lett 8, 935-938.

Pemberton, N., Pinkner, J.S., Edvinsson, S., Hultgren, S.J., and Almqvist, F. (2008). Synthesis and evaluation of dihydroimidazolo and dihydrooxazolo ring-fused 2-pyridones - targeting pilus biogenesis in uropathogenic bacteria. Tetrahedron 64, 9368-9376.

Petersson, C., Forsberg, M., Aspholm, M., Olfat, F., Forslund, T., Borén, T., and Magnusson, K. (2006). Helicobacter pylori SabA adhesin evokes a strong inflammatory response in human neutrophils which is down-regulated by the neutrophil-activating protein. Med Microbiol Immunol 195, 195-206.

Pinkner, J., Remaut, H., Buelens, F., Miller, E., Aberg, V., Pemberton, N., Hedenström, M., Larsson, A., Seed, P., Waksman, G., et al. (2006). Rationally designed small compounds inhibit pilus biogenesis in uropathogenic bacteria. Proc Natl Acad Sci U S A 103, 17897-17902.

Pinne, M., Denker, K., Nilsson, E., Benz, R., and Bergström, S. (2006). The BBA01 protein, a member of paralog family 48 from Borrelia burgdorferi, is potentially interchangeable with the channel-forming protein P13. J Bacteriol 188, 4207-4217.

Rydén, P., Andersson, H., Landfors, M., Näslund, L., Hartmanová, B., Noppa, L., and Sjöstedt, A. (2006). Evaluation of microarray data normalization procedures using spike-in experiments. BMC Bioinformatics 7, 300.

Segerman, A., Lindman, K., Mei, Y., Allard, A., and Wadell, G. (2006). Adenovirus types 11p and 35 attach to and infect primary lymphocytes and monocytes, but hexon expression in T-cells requires prior activation. Virology 349, 96-111.

Tedeschi, R., Bidoli, E., Agren, A., Hallmans, G., Wadell, G., De Paoli, P., and Dillner, J. (2006). Epidemiology of Kaposi's Sarcoma herpesvirus (HHV8) in Västerbotten County, Sweden. J Med Virol 78, 372-378.

Vaitkevicius, K., Lindmark, B., Ou, G., Song, T., Toma, C., Iwanaga, M., Zhu, J., Andersson, A., Hammarström, M., Tuck, S., et al. (2006). A Vibrio cholerae protease needed for killing of Caenorhabditis elegans has a role in protection from natural predator grazing. Proc Natl Acad Sci U S A 103, 9280-9285.

Wiley, D., Nordfeldth, R., Rosenzweig, J., DaFonseca, C., Gustin, R., Wolf-Watz, H., and Schesser, K. (2006). The Ser/Thr kinase activity of the Yersinia protein kinase A (YpkA) is necessary for full virulence in the mouse, mollifying phagocytes, and disrupting the eukaryotic cytoskeleton. Microb Pathog 40, 234-243.

Åkesson, P., Moritz, L., Truedsson, M., Christensson, B., and von Pawel-Rammingen, U. (2006). IdeS, a highly specific immunoglobulin G (IgG)-cleaving enzyme from Streptococcus pyogenes, is inhibited by specific IgG antibodies generated during infection. Infect Immun 74, 497-503.

Yasmin, L., Jansson, A., Panahandeh, T., Palmer, R., Francis, M., and Hallberg, B. (2006). Delineation of exoenzyme S residues that mediate the interaction with 14-3-3 and its biological activity. FEBS J 273, 638-646.

Åberg, V., Sellstedt, M., Hedenström, M., Pinkner, J., Hultgren, S., and Almqvist, F. (2006). Design, synthesis and evaluation of peptidomimetics based on substituted bicyclic 2-pyridones-targeting virulence of uropathogenic E. coli. Bioorg Med Chem 14, 7563-7581.

Publikationer 2005

Björnham, O., Fällman, E., Axner, O., Ohlsson, J., Nilsson, U.J., Boren, T., and Schedin, S. (2005). Measurements of the binding force between the Helicobacter pylori adhesin BabA and the Lewis b blood group antigen using optical tweezers. J Biomed Opt 10, 44024.

Bröms, J.E., Edqvist, P.J., Carlsson, K.E., Forsberg, A., and Francis, M.S. (2005). Mapping of a YscY binding domain within the LcrH chaperone that is required for regulation of Yersinia type III secretion. J Bacteriol 187, 7738-7752.

Fällman, E., Schedin, S., Jass, J., Uhlin, B.E., and Axner, O. (2005). The unfolding of the P pili quaternary structure by stretching is reversible, not plastic. EMBO Rep 6, 52-56.

Fällman, M., and Gustavsson, A. (2005). Cellular mechanisms of bacterial internalization counteracted by Yersinia. Int Rev Cytol 246, 135-188.

Hainzl, T., Huang, S., and Sauer-Eriksson, A.E. (2005). Structural insights into SRP RNA: an induced fit mechanism for SRP assembly. RNA 11, 1043-1050.

Hedenström, M., Emtenäs, H., Pemberton, N., Åberg, V., Hultgren, S.J., Pinkner, J.S., Tegman, V., Almqvist, F., Sethson, I., and Kihlberg, J. (2005). NMR studies of interactions between periplasmic chaperones from uropathogenic E. coli and pilicides that interfere with chaperone function and pilus assembly. Org Biomol Chem 3, 4193-4200.

Hörnberg, A., Hultdin, U.W., Olofsson, A., and Sauer-Eriksson, A.E. (2005). The effect of iodide and chloride on transthyretin structure and stability. Biochemistry 44, 9290-9299.

Johansson, S.M., Arnberg, N., Elofsson, M., Wadell, G., and Kihlberg, J. (2005). Multivalent HSA conjugates of 3'-sialyllactose are potent inhibitors of adenoviral cell attachment and infection. Chembiochem 6, 358-364.

Karlsson, A., Olofsson, A., Eneqvist, T., and Sauer-Eriksson, A.E. (2005). Cys114-linked dimers of transthyretin are compatible with amyloid formation. Biochemistry 44, 13063-13070.

Larsson, A., Johansson, S.M., Pinkner, J.S., Hultgren, S.J., Almqvist, F., Kihlberg, J., and Linusson, A. (2005). Multivariate design, synthesis, and biological evaluation of peptide inhibitors of FimC/FimH protein-protein interactions in uropathogenic Escherichia coli. J Med Chem 48, 935-945.

Larsson, P., Oyston, P.C., Chain, P., Chu, M.C., Duffield, M., Fuxelius, H.H., Garcia, E., Halltorp, G., Johansson, D., Isherwood, K.E., et al. (2005). The complete genome sequence of Francisella tularensis, the causative agent of tularemia. Nat Genet 37, 153-159.

Lindgren, H., Stenman, L., Tarnvik, A., and Sjöstedt, A. (2005). The contribution of reactive nitrogen and oxygen species to the killing of Francisella tularensis LVS by murine macrophages. Microbes Infect 7, 467-475.

Mogemark, L., McGee, K., Yuan, M., Deleuil, F., and Fällman, M. (2005). Disruption of target cell adhesion structures by the Yersinia effector YopH requires interaction with the substrate domain of p130Cas. Eur J Cell Biol 84, 477-489.

Nordfelth, R., Kauppi, A.M., Norberg, H.A., Wolf-Watz, H., and Elofsson, M. (2005). Small-molecule inhibitors specifically targeting type III secretion. Infect Immun 73, 3104-3114.

Olfat, F.O., Zheng, Q., Oleastro, M., Voland, P., Boren, T., Karttunen, R., Engstrand, L., Rad, R., Prinz, C., and Gerhard, M. (2005). Correlation of the Helicobacter pylori adherence factor BabA with duodenal ulcer disease in four European countries. FEMS Immunol Med Microbiol 44, 151-156.

Pemberton, N., Emtenäs, H., Bostrom, D., Domaille, P.J., Greenberg, W.A., Levin, M.D., Zhu, Z., and Almqvist, F. (2005). Cycloaddition of delta2-thiazolines and acyl ketenes under acidic conditions results in bicyclic 1,3-oxazinones and not 6-acylpenams as earlier reported. Org Lett 7, 1019-1021.

Telepnev, M., Golovliov, I., and Sjöstedt, A. (2005). Francisella tularensis LVS initially activates but subsequently down-regulates intracellular signaling and cytokine secretion in mouse monocytic and human peripheral blood mononuclear cells. Microb Pathog 38, 239-247.

Twine, S., Byström, M., Chen, W., Forsman, M., Golovliov, I., Johansson, A., Kelly, J., Lindgren, H., Svensson, K., Zingmark, C., et al. (2005). A mutant of Francisella tularensis strain SCHU S4 lacking the ability to express a 58-kilodalton protein is attenuated for virulence and is an effective live vaccine. Infect Immun 73, 8345-8352.

Wallner, F.K., Norberg, H.A., Johansson, A.I., Mogemark, M., and Elofsson, M. (2005). Solid-phase synthesis of serine-based glycosphingolipid analogues for preparation of glycoconjugate arrays. Org Biomol Chem 3, 309-315.

Yuan, M., Deleuil, F., and Fallman, M. (2005). Interaction between the Yersinia tyrosine phosphatase YopH and its macrophage substrate, Fyn-binding protein, Fyb. J Mol Microbiol Biotechnol 9, 214-223.

Yuan, M., Mogemark, L., and Fallman, M. (2005). Fyn binding protein, Fyb, interacts with mammalian actin binding protein, mAbp1. FEBS Lett 579, 2339-2347.

Åberg, V., Hedenstrom, M., Pinkner, J.S., Hultgren, S.J., and Almqvist, F. (2005). C-Terminal properties are important for ring-fused 2-pyridones that interfere with the chaperone function in uropathogenic E. coli. Org Biomol Chem 3, 3886-3892.

Åberg, V., Norman, F., Chorell, E., Westermark, A., Olofsson, A., Sauer-Eriksson, A.E., and Almqvist, F. (2005). Microwave-assisted decarboxylation of bicyclic 2-pyridone scaffolds and identification of Abeta-peptide aggregation inhibitors. Org Biomol Chem 3, 2817-2823.