The aim of the course is to give the student a solid fundament in analytical chemistry, focusing mainly on classical but still widely used wet chemical methods, combined with an overview of the instrumental techniques used in contemporary chemical analysis to prepare for further studies. Following an intro¬duction to analytical chemistry from a historical and philosophical viewpoint, the fundamentals of the analytical process are discussed with focus on isolation, detection, quantitation and identification of solutes. The importance of docu¬mentation is stressed, in particular workflows for establisment of reliable analytical protocols, proper logging and evaluation of experiments, etc. The sampling process is given a central role, specifically addressing ways to ascertain representativity, homogeneity and integrity for samples taken from matrixes of different physical states. Proper sample size and estimation/propagation of errors are discussed, as are calibration and standards, along with sources of interference and ways of handling these in analytical measurements. Statistical treatment of experimental errors is taught, with focus on ways of quality assuring measurements. Among the classical methods treated in the course are gravimetry, combustion methods, and titrations (acid-base, redox, complexometric, and non-aqueous). Fundamentals of electrochemical methods are dealt with, focusing on potentiometry (ion selective electrodes including pH), coulometry/ampero¬metry, and voltammetry. Included are also fundamentals and applications of atomic and molecular spectrometry, an introduction to chromatographic and electrophoretic separation techniques, and radiochemical methods. Tuition is given as lectures, problem solving classes, and tutorials. Laboratory exercises follow the curriculum and include setting up and running some classical analysis methods according to standard procedures, as well as training in basic electrochemical, spectrophotometric and chromatographic methods.
The course will be given in english if foreign students participate.
